Bonus Features – February 12, 2023 – Epic tops Best in KLAS for 13th straight year, 89% of healthcare finance leaders remain confident in 2023, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News The Biden Administration announced the latest initiatives in the reignited Cancer Moonshot program. One initiative of interest to the healthcare IT community is CancerX, a public-private innovation partnership to develop to...
Source: EMR and HIPAA - February 12, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT AdvancedMD Alloantibody Exchange Beacon Health System Best in KLAS Biden Biofourmis Brooke Bowers Cancer Moonshot CareCloud CHG Healthcare CIvitas Clean Air CMS Complete Care David Feinberg DexCare DrFirst Source Type: blogs

Microglial Autophagy in the Context of Neurodegenerative Conditions
Changes in the function and activity of microglia in the brain, innate immune cells analogous to the macrophages present in the rest of the body, are known to be involved in the onset and progression of neurodegenerative conditions. Aging and neurodegeneration are associated with a growing presence of both senescent microglia and activated microglia Both of these states producing inflammatory signaling, contributing to the chronic, unresolved inflammation of brain tissue that is also characteristic of later life. Autophagy is the name given to a collection of cellular maintenance processes responsible for recycling ...
Source: Fight Aging! - February 10, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Voice-Activated Sample Prep for Safer Handling
Researchers at Kyung Hee University in South Korea have developed a voice-activated DNA sample pre-treatment device to assist clinicians dealing with outbreaks of infectious disease to stay safer. Dealing with highly infectious patient samples puts clinicians and lab technicians at risk. Minimizing sample handling and exposure is important in reducing the risk of transmission, and a system that can perform some of these steps automatically, without a clinician even having to interact with it physically can facilitate this. Another application is to allow biomedical scientists with a disability that might preclude them from...
Source: Medgadget - February 9, 2023 Category: Medical Devices Authors: Conn Hastings Tags: etc. Genetics Pathology Public Health Source Type: blogs

Reviewing the Development of Senotherapeutics
Today's open access paper is a very readable tour of the present state of research and development of therapies targeting senescent cells, whether to destroy them or alter their function in favorable ways. In both cases the primary goal is to reduce the senescence-associated secretory phenotype (SASP), the pro-growth, pro-inflammatory signaling that contributes to degenerative aging as the number of senescent cells rises over the course of later life. It is hoped that clearance of senescent cells will produce a sizable positive impact for late life health, reducing chronic inflammation, slowing the onset of near all age-re...
Source: Fight Aging! - February 7, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Fight Aging! Newsletter, February 6th 2023
In conclusion, our study reveals that aging enhances atherosclerosis via increased inflammation of visceral fat. Our study suggests that future therapies targeting the visceral fat may reduce atherosclerosis diseaseburden in the expanding older population. Is the Gut a Significant Source of Amyloid-β in Alzheimer's Disease? https://www.fightaging.org/archives/2023/02/is-the-gut-a-significant-source-of-amyloid-%ce%b2-in-alzheimers-disease/ The early stages of Alzheimer's disease are characterized by rising levels of amyloid-β in the brain and the formation of misfolded amyloid aggregates. It is present...
Source: Fight Aging! - February 5, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Weekly Roundup – February 4, 2023
Welcome to our Healthcare IT Today Weekly Roundup. Each week, we’ll be providing a look back at the articles we posted and why they’re important to the healthcare IT community. We hope this gives you a chance to catch up on anything you may have missed during the week. Is a Healthcare Chatbot Explosion on The Way? Given the sudden surge in interest in ChatGPT, Anne Zieger addressed the question on everyone’s mind. Her take: Though chatbots face challenging headwinds – including limited exposure to medical terminology and, critically, a lack of empathy – healthcare should be open to any tools that keep...
Source: EMR and HIPAA - February 4, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Healthcare IT Today Weekly Roundup Source Type: blogs

With access to my records, I took my business elsewhere
By EPATIENT DAVE DEBRONKART Not our usual headshot but it is Dave! I had a skin cancer diagnosed in November. It’s my third, and I researched the last one heavily, so I knew what I wanted (Mohs on the nose). But the hospital that did the diagnosis insisted I wait and have a consult visit in January, and *then* they’d let me schedule the procedure, probably in March. I said I know what treatment I want – can’t I schedule the surgery now? They said, “That’s not how we do it.” So I went home and called around. Beth Israel Deaconess Medical Center said if I could get th...
Source: The Health Care Blog - February 4, 2023 Category: Consumer Health News Authors: matthew holt Tags: The Business of Health Care BIDMC ePatient Dave patient records TEFCA Source Type: blogs

Arguing Semantics in the Matter of Normal Aging
Researchers here complain about the term "normal aging", suggesting that it is misleading. There is certainly no shortage of problematic language in the description of aging. "Healthy aging" is a contradiction in terms that is widely used to justify a focus on marginal therapies that cannot even in principle achieve rejuvenation, for example. Does it help progress for language to be aligned with goals? Likely, though perhaps only in the longer term. It is clear that a good portion of the research community is already interested in treating aging as a medical condition, regardless of the language used - but more widespread ...
Source: Fight Aging! - February 3, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Is the Gut a Significant Source of Amyloid- β in Alzheimer's Disease?
The early stages of Alzheimer's disease are characterized by rising levels of amyloid-β in the brain and the formation of misfolded amyloid aggregates. It is presently thought that this is a necessary precursor for the more harmful later stages of the condition, in which chronic inflammation and tau aggregation cause widespread cell death in the brain. It has been noted that amyloid-β exists outside the brain, and there is evidence for levels of amyloid-β in the vasculature to be in dynamic equilibrium with amyloid-β in the brain. Clearing amyloid-β from the bloodstream has shown some promise as an approach to reduce ...
Source: Fight Aging! - February 2, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Deciphex Secures €3.9m Funding to Boost Digital Pathology and AI Services
The company is seeing a ten-fold increase in demand quarterly and this strategic investment will allow them to grow their capacity, increase headcount, further improve services and expand to new markets Deciphex, a leading provider of pathology software and services, announced today a further €3.9m in funding bringing its full Series B round tally to €14.4m. The additional investment, led by Seroba Life Sciences and existing Deciphex investors, will allow Deciphex to continue developing its innovative products and services, to expand its presence in the UK, Canada, the Middle East and the US, and to strengthen its posi...
Source: EMR and HIPAA - February 2, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Chronic Issues Deciphex Diagnexia digital pathology Digital Pathology Funding Donal O’Shea Health IT Funding Health IT Fundings Health IT Investment Jennifer McMahon Optimal Patient Care Patholyt Source Type: blogs

Primary PCI and its silent encounter with “ myocardial neutrophilia ”
Myocardial infarction,  a gross pathological entity renamed now as STEMI for clinical purposes, is the most famous medical emergency that triggers a series of calls. Right from 911/First medical contact, the ER, that ends up in CCU or a 24/7 cath lab. The heart, can’t wait for all these external responses when it is challenged with a vascular accident. The moment ATO occurs, two things happen. The endogenous fibrinolytic led by native tissue PA (Tpa) tries to get rid of the thrombotic plug by all its means. It succeeds in 15%. We call it spontaneous lysis or aborted MI. Many lives are lost in the remaining before th...
Source: Dr.S.Venkatesan MD - February 1, 2023 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized myocardial neutrophilia Source Type: blogs

Fight Aging! Newsletter, January 30th 2023
In conclusion, deletion of p16Ink4a cells did not negatively impact beta-cell mass and blood glucose under basal and HFD conditions and proliferation was restored in a subset of HFD mice opening further therapeutic targets in the treatment of diabetes. Communication Between Blood and Brain in Aging and Rejuvenation https://www.fightaging.org/archives/2023/01/communication-between-blood-and-brain-in-aging-and-rejuvenation/ As noted here, joining the circulatory systems of an old and young mouse results in some degree of rejuvenation in the old mouse. Where brain function is improved, researchers are inte...
Source: Fight Aging! - January 29, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Dueling OMI: does this 30 year old with chest pain have any signs of occlusion or reperfusion?
Written by Jesse McLaren, with edits from Smith A 30 year old with a history of diabetes presented with two days of intermittent chest pain and diaphoresis, which recurred two hours prior to presentation. Below is ECG #1 at triage. Are there any signs of occlusion or reperfusion?There ’s normal sinus rhythm, normal conduction, normal axis, normal R wave progression and normal voltages. There’s mild inferior ST elevation in III that doesn’t meet STEMI criteria, but it’s associated with ST depression in aVL and V2 that makes itdiagnostic of infero-posterior Occlusion MI (from either RCA or circumflex) – accomp...
Source: Dr. Smith's ECG Blog - January 29, 2023 Category: Cardiology Authors: Jesse McLaren Source Type: blogs

Senotherapeutics Will Reduce the Side-Effects of Cancer Radiotherapy
Treatment with radiation to kill cancerous cells results in an increased burden of senescent cells, both in and around the tumor. This is a fair trade-off; a senescent cancerous cell may be harmful in and of itself, but it is a good deal less harmful in the long run than an active cancer cell. Unfortunately senescent cells produce pro-growth, pro-inflammatory signaling that is disruptive of tissue function, raises the risk of suffering a range of age-related conditions, and increases the risk of both reoccurrence of the treated cancer and the development of later unrelated cancers. Thus given the work taking place o...
Source: Fight Aging! - January 24, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Discussing the Hallmarks of Aging in the Context of Alzheimer's Disease
This article will focus on the primary aging hallmarks as these are interconnected with other aging characteristics and are at the base of the hierarchical order of aging features, and have been shown to be related to AD. It is an attempt to improve our understanding of the pathological mechanisms of AD to find potential therapeutic approaches and diagnostic tools. Link: https://doi.org/10.7150/thno.79535 (Source: Fight Aging!)
Source: Fight Aging! - January 24, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs