NeuroBreak: Opioid Scripts Down at the VA; Paxil on Trial
(MedPage Today) -- News and commentary from the world of neurology and neuroscience (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - March 14, 2017 Category: Geriatrics Source Type: news
Lupin launches generic anti-depression drug in US
The company "announced the launch of generic paxil CR extended release tablets, 12.5 mg, 25 mg and 37.5 mg, having received an approval from the USFDA earlier (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - March 7, 2017 Category: Pharmaceuticals Source Type: news
Paxil (Paroxetine Hydrochloride) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 25, 2016 Category: Drugs & Pharmacology Source Type: news
Paxil-CR (Paroxetine Hydrochloride) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 25, 2016 Category: Drugs & Pharmacology Source Type: news
Brisdelle (Paroxetine Capsules 7.5 mg) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 25, 2016 Category: Drugs & Pharmacology Source Type: news
Pexeva (Paroxetine Mesylate) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 15, 2016 Category: Drugs & Pharmacology Source Type: news
3 Drugs with the Most Severe Side Effects
Image Source
Drugs have been known to have some sort of side effects on patients. Most of them are not often discussed in the health tabloids. While other drugs have side effects that are very nominal when compared to the benefits the patient derives from their usage, others have side effects that can impact the lives of their users forever.
The most common side effects people experience from drug usage are gastrointestinal related issues which include constipation, nausea, and vomiting. Some other drugs can leave you feeling tired and dizzy for a short period of time. Combining these drugs with simple aspirin will usuall...
Source: Healthy Living - The Huffington Post - August 19, 2016 Category: Consumer Health News Source Type: news
Comparative risk of hip fractures in elderly nursing home patients with depression using paroxetine and other selective serotonin reuptake inhibitors - Bali V, Chatterjee S, Johnson ML, Chen H, Carnahan RM, Aparasu RR.
AIM: To evaluate comparative safety of paroxetine and other selective serotonin reuptake inhibitors (SSRIs) for the risk of hip fractures. Patients & methods: A propensity score-matched retrospective cohort study was conducted using 2007-2010 Minimum Data ... (Source: SafetyLit)
Source: SafetyLit - July 28, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news
Study Defends Antidepressant Use In Pregnancy Despite Birth Defect Risks
While SSRI antidepressants are arguably still the most consumed drug class in the US, sales peaked in 2008 and have declined by four percent every year since, according to Research and Markets.
There are many reasons for declining SSRI sales from unwanted side effects like weight gain and sexual dysfunction to "Prozac Poop-out" in which patients develop tolerance and the pills quit working.
Still, a major reason for declining sales are SSRI's strong links to suicide and birth defects.
In 2004, the FDA added "Black Box" warnings to SRRIs, highlighting suicide risks and the need for close monitoring of children and adoles...
Source: Healthy Living - The Huffington Post - July 26, 2016 Category: Consumer Health News Source Type: news
Both paroxetine and impramine appear to be ineffective in adolescents with major depression, furthermore doubts have risen about their safety
Adolescents suffering from major depression often receive treatment with antidepressants.
However the evidence for the efficacy of both newer antidepressants and tricyclic antidepressants in major depression in adolescence is very limited. Systematic reviews1 found a statistically significant difference in efficacy in favour of antidepressants versus placebo, which was not clinically relevant. However, they concluded that the large majority of studies on this topic shows serious methodological flaws, selecting patients ...
Source: Current Awareness Service for Health (CASH) - July 12, 2016 Category: Consumer Health News Source Type: news
paroxetine (Brisdelle)
Title: paroxetine (Brisdelle)Category: MedicationsCreated: 2/24/2015 12:00:00 AMLast Editorial Review: 7/8/2016 12:00:00 AM (Source: MedicineNet Menopause General)
Source: MedicineNet Menopause General - July 8, 2016 Category: Primary Care Source Type: news
Fentanyl can cause serotonin syndrome
3.5 out of 5 stars
Serotonin Syndrome Induced by Fentanyl in a Child: Case Report. Robles LA. Clin Neuropharmacol 2015 Sept-Oct;38:206-8.
Abstract
When many clinicians think of serotonin syndrome (SS), they consider the usual suspects:
Selective Serotonin Uptake Inhibitors (SSRIs)
Citalopram
Fluoxetine
Sertraline
Escitalopram
Paroxetine
Serotonin-Norepinephrine Reuptake Inhibitors
Venlafaxine
Duloxetine
Antidepressants
Trazodone
Buspirone
Clomipramine
Aside from these common culprits, there are other commonly used drugs whose clear association with serotonin syndrome is less-often realized:
Fentanyl
Methadon...
Source: The Poison Review - July 8, 2016 Category: Toxicology Authors: Leon Gussow Tags: Medical fentanyl opioid serotonin syndrome Source Type: news
Depression blood test could lead to personalised treatments
Conclusion
This study shows how a new blood test in development can help identify people with depression who are most and least likely to benefit from antidepressants.
While promising, the test is far from perfect. For example, it missed 39-43% of non-responders, meaning these people would continue to receive standard antidepressant treatment that is unlikely to work for them.
A large proportion of patients (22-38%) also fell into the "intermediate" group who were neither responders nor non-responders, so the test wasn't too useful here.
This means there is a significant proportion of people with depression ...
Source: NHS News Feed - June 7, 2016 Category: Consumer Health News Tags: Mental health Medication Source Type: news
Researchers visualize brain's serotonin pump, provide blueprint for new, more effective SSRIs
Researchers have uncovered remarkably detailed 3-D views of one of the most important transporters in the brain -- the serotonin transporter. Their study provides fresh insight into how citalopram and paroxetine, two of the most widely prescribed selective serotonin reuptake inhibitors, or SSRIs, interact with and inhibit serotonin transport. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 6, 2016 Category: Science Source Type: news
Researchers visualize brain's serotonin pump, provide blueprint for new, more effective SSRIs
(Oregon Health & Science University) Researchers at Oregon Health & Science University's Vollum Institute have uncovered remarkably detailed 3-D views of one of the most important transporters in the brain -- the serotonin transporter. Their study, published online today in the journal Nature, provides fresh insight into how citalopram and paroxetine, two of the most widely prescribed selective serotonin reuptake inhibitors, or SSRIs, interact with and inhibit serotonin transport. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 6, 2016 Category: Biology Source Type: news