Impact of tight blood glucose control within normal fasting ranges with insulin titration prescribed by the Leuven algorithm in adult critically ill patients: the TGC-fast randomized controlled trial
DiscussionThe ideal glucose target for critically ill patients remains debated. The trial will inform physicians on the optimal glucose control strategy in adult critically ill patients not receiving early PN.Trial registrationClinicalTrials.gov NCT03665207. Registered on 11 September 2018. (Source: Trials)
Source: Trials - September 19, 2022 Category: Research Source Type: clinical trials

Control of Line Complications with KiteLock (CLiCK) in the critical care unit: study protocol for a multi-center, cluster-randomized, double-blinded, crossover trial investigating the effect of a novel locking fluid on central line complications in the critical care population
DiscussionIf successful, the results of this study can serve as evidence for a shift of standard of care practices to include EDTA locking fluid in routine CVAD locking procedures. Completion of this study has the potential to improve CVAD standard of care to become safer for patients, as well as provides an opportunity to decrease strain on healthcare budgets related to treating preventable CVAD complications. Success and subsequent implementation of this intervention in the ICU may also be extrapolated to other patient populations with heavy CVAD use including hemodialysis, oncology, parenteral nutrition, and pediatric p...
Source: Trials - August 30, 2022 Category: Research Source Type: clinical trials

Does Volume-based Enteral Feeding Improve Nutrient Delivery in Hospitalized Critically Ill Children?
Condition:   Enteral Feeding Interventions:   Procedure: Volume-based EN;   Procedure: Rate-based EN Sponsors:   University of Calgary;   American Society for Parenteral and Enteral Nutrition;   Alberta Health Services Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 18, 2022 Category: Research Source Type: clinical trials