Antibody positive autoimmune encephalitis presenting with faciobrachial dystonic seizures-Case Report
63 year old male presented with new onset faciobrachial dystonic seizures. Imaging showed T2 Flair hyperintensity in left hippocampus. Possibility of autoimmune encephalitis was considered and we went for CSF autoantibody study.Result came as positive for LGI 1 (Leucine rich Glioma Inactivated-1) antibody in CSF.We also did a paraneoplastic work up to rule out any underlying malignancy. But was unyielding. Patient was treated with steroid pulse with methylprednisolone for 5 days. Subsequently, he was continued on oral steroids. Patient improved. No further seizure episodes. Patient is being kept on follow...
Source: Sumer's Radiology Site - December 9, 2018 Category: Radiology Authors: Sumer Sethi Source Type: blogs
Tropical Travel Trouble 009 Humongous HIV Extravaganza
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
aka Tropical Travel Trouble 009
The diagnosis of HIV is no longer fatal and the term AIDS is becoming less frequent. In many countries, people with HIV are living longer than those with diabetes. This post will hopefully teach the basics of a complex disease and demystify some of the potential diseases you need to consider in those who are severely immunosuppressed. While trying to be comprehensive this post can not be exhaustive (as you can imagine any patient with a low ...
Source: Life in the Fast Lane - July 7, 2018 Category: Emergency Medicine Authors: Amanda McConnell Tags: Clinical Cases Tropical Medicine AIDS art cryptococcoma cryptococcus HIV HIV1 HIV2 PEP PrEP TB toxoplasma tuberculoma Source Type: blogs
How To Prevent Burnout. Frederick This One.
By MARTIN A. SAMUELS
I posted an essay on The Health Care Blog entitled The Prevention of Physician Burnout: A Nine Step Program. Here is an example of how this works. Recall the wonderful children’s book by Leo Lionni, Frederick. Let me remind you of it.
A family of mice begins to store away food and supplies for the long winter ahead. Most are practical and gather corn, grains, and straw. One of the mice, Frederick, instead collects rays of sun, colors of the rainbow, and words to remember. When winter arrives the family begins to use up their practical supplies. They become irritable and angry and don’t h...
Source: The Health Care Blog - August 25, 2017 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized Burnout Frederick Martin Samuels Source Type: blogs
How To Prevent Burnout: A Case in Point. Frederick This One.
By MARTIN A. SAMUELS
I posted an essay on The Health Care Blog (entitled The Prevention of Physician Burnout: A Nine Step Program. Here is an example of how this works. Recall the wonderful children’s book by Leo Lionni, Frederick. Let me remind you of it.
A family of mice begins to store away food and supplies for the long winter ahead. Most are practical and gather corn, grains, and straw. One of the mice, Frederick, instead collects rays of sun, colors of the rainbow, and words to remember. When winter arrives the family begins to use up their practical supplies. They become irritable and angry and don’t ...
Source: The Health Care Blog - August 25, 2017 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized Source Type: blogs
Autoimmune meningoencephalitis associated with GFAP IgG antibodies.
var gaJsHost = (( " https: " == document.location.protocol) ? " https://ssl. " : " http://www. " ); document.write(unescape( " %3Cscript src= ' " + gaJsHost + " google-analytics.com/ga.js ' type= ' text/javascript ' %3E%3C/script%3E " ));var pageTracker = _gat._getTracker( " UA-3639768-12 " ); pageTracker._initData(); pageTracker._trackPageview();Fung B et al. Autoimmune glial fibrillary acidic protein astrocytopathy: a novel meningoencephalomyelitis. JAMA Neurol 2016; 73: 1297.Mayo labs has 134 cases out of 100,000 evaluated for autoimmune and paraneoplastic ab ' s as part of routine care. Clinical prese...
Source: neurologyminutiae - February 7, 2017 Category: Neurology Source Type: blogs
Paraneoplastic rheumatic syndromes
(Source: Notes from Dr. RW)
Source: Notes from Dr. RW - February 21, 2014 Category: Internists and Doctors of Medicine Tags: oncology rheumatology Source Type: blogs
Gliadin: The Universal Human Poison
Autoimmunity is the process describing an immune response waged against our own organs. The complex collection of mechanisms consisting of T and B lymphocytes, antibodies, and others, meant to provide protection against viruses, bacteria, and other body invaders, is misdirected against proteins of the body’s organs, such as liver, pancreas, thyroid, or brain. Autoimmune conditions now affect 8% of the American population–it is increasingly looking like diseases of autoimmunity are out of control.
Dr Alessio Fasano was recently awarded the Linus Pauling Award, the highest award from the Institute for Functional...
Source: Wheat Belly Blog - October 7, 2013 Category: Cardiology Authors: Dr. Davis Tags: Autoimmunity Gliadin Source Type: blogs
Medical Mispronunciations and Misspelled Words: The Definitive List.
Hearing medical mispronunciations and seeing misspelled words are an under appreciated joy of working in healthcare. Physicians often forget just how alien the language of medicine is to people who don't live it everyday. The best part about being a physician is not helping people recover from critical illness. The best part is not about listening and understanding with compassion and empathy. Nope, the best part about being a physician is hearing patients and other healthcare providers butcher the language of medicine and experiencing great entertainment in the process. Doctors c...
Source: The Happy Hospitalist - October 2, 2013 Category: Internists and Doctors of Medicine Authors: Tamer Mahrous Source Type: blogs
Paraneoplastic antibody screening
Can you teach an old dog new tricks? Apparently this old dog learns slowly, but is capable of learning. Over the past 2 years I have listened to fascinating case presentations that involved paraneoplastic screening.
If you are clueless, I found this website – Paraneoplastic Neurological Disorders
While this is helpful, it may not help most physicians. This is my understanding (and please correct me if I am incorrect)
This bucket contains a variety of neurological disorders:
"Paraneoplastic" means that the neurologic problem is not caused by the cancer itself, but by disturbances th...
Source: DB's Medical Rants - January 25, 2013 Category: Health Medicine and Bioethics Commentators Authors: rcentor Tags: Medical Rants Source Type: blogs
