Paget Disease of the Nipple Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Paget's disease of the breast: diagnosis and management
Br J Hosp Med (Lond). 2023 Jan 2;84(1):1-8. doi: 10.12968/hmed.2022.0439. Epub 2023 Jan 24.ABSTRACTPaget's disease of the breast typically affects postmenopausal women and is associated with an underlying malignancy. Skin changes are a common presenting symptom, as well as a lump, nipple discharge, pain and changes to the nipple shape. Imaging options include ultrasound for women under the age of 35 years or mammogram and ultrasound for women over the age of 40 years. The definitive diagnostic investigation is a tissue core biopsy. Cases are discussed by a multidisciplinary team to decide on the optimal management strategy...
Source: British Journal of Hospital Medicine - January 28, 2023 Category: Internal Medicine Authors: Sarah Hudson-Phillips Kofi Cox Puja Patel Wail Al Sarakbi Source Type: research

Nipple-Sparing Mastectomy After Neoadjuvant Chemotherapy: Definitive Results with a Long-Term Follow-Up Evaluation
CONCLUSIONS: The study data definitively confirm that NSM is safe even after NACT, with good cosmetic results and complications comparable with those in the primary surgery setting. Tumor stage and age were the only independent factors for local relapse. Patients with pCR enjoyed optimal locoregional control.PMID:36598627 | DOI:10.1245/s10434-022-13035-5 (Source: Cancer Control)
Source: Cancer Control - January 4, 2023 Category: Cancer & Oncology Authors: Emanuele Zarba Meli Anna De Santis Giuliana Cortese Elena Manna Tiziana Mastropietro Massimo La Pinta Andrea Loreti Floriana Arelli Paola Scavina Mauro Minelli Angela Damiana Andrulli Leopoldo Costarelli Laura Broglia Tatiana Ponzani Lucio Fortunato Source Type: research

Nipple-Sparing Mastectomy After Neoadjuvant Chemotherapy: Definitive Results with a Long-Term Follow-Up Evaluation
CONCLUSIONS: The study data definitively confirm that NSM is safe even after NACT, with good cosmetic results and complications comparable with those in the primary surgery setting. Tumor stage and age were the only independent factors for local relapse. Patients with pCR enjoyed optimal locoregional control.PMID:36598627 | DOI:10.1245/s10434-022-13035-5 (Source: Ann Oncol)
Source: Ann Oncol - January 4, 2023 Category: Cancer & Oncology Authors: Emanuele Zarba Meli Anna De Santis Giuliana Cortese Elena Manna Tiziana Mastropietro Massimo La Pinta Andrea Loreti Floriana Arelli Paola Scavina Mauro Minelli Angela Damiana Andrulli Leopoldo Costarelli Laura Broglia Tatiana Ponzani Lucio Fortunato Source Type: research

Paget ’s disease of the breast: Our 20 years’ experience
ConclusionPD is a rare form of breast cancer and, in half of the cases, is associated with an invasive carcinoma. Separating our sample into three subgroups based on tumor histology, there were no significant differences in terms of LC, DFS, and OS rate in patients treated with different types of surgery. This study presents some limitations due to its retrospective nature and being confined to a single institution. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - November 22, 2022 Category: Cancer & Oncology Source Type: research

Examining racial differences in treatment and survival among patients with Paget ’s disease of the breast
The objective of this study was to evaluate racial differences in treatment (ie, surgery, chemotherapy, and radiation) and survival among patients with Paget ’s disease of the breast in the Surveillance, Epidemiology and End Result program. (Source: Surgery)
Source: Surgery - October 20, 2022 Category: Surgery Authors: Nicci Owusu-Brackett, JC Chen, Yaming Li, James L. Fisher, Oindrila Bhattacharyya, Samilia Obeng-Gyasi Source Type: research