Pagets sykdom i brystvorten
Tidsskr Nor Laegeforen. 2023 Mar 21;143(5). doi: 10.4045/tidsskr.22.0390. Print 2023 Mar 28.ABSTRACTBACKGROUND: Paget's disease of the nipple comprises approximately 1 % of all breast cancers, and presents with unilateral eczematoid changes to the nipple, areola or surrounding skin. Symptoms can be pain, itching or stinging in the area.CASE PRESENTATION: A female patient in her sixties presented to the skin clinic 18 months after initial detection of a rash surrounding her left nipple. Earlier ultrasound and mammography had not indicated pathology. Clinical suspicion and punch biopsies revealed a ductal carcinoma in situ. ...
Source: Tidsskrift for den Norske Laegeforening - March 29, 2023 Category: General Medicine Authors: Claus L ützow-Holm Source Type: research

Pagets sykdom i brystvorten
Tidsskr Nor Laegeforen. 2023 Mar 21;143(5). doi: 10.4045/tidsskr.22.0390. Print 2023 Mar 28.ABSTRACTBACKGROUND: Paget's disease of the nipple comprises approximately 1 % of all breast cancers, and presents with unilateral eczematoid changes to the nipple, areola or surrounding skin. Symptoms can be pain, itching or stinging in the area.CASE PRESENTATION: A female patient in her sixties presented to the skin clinic 18 months after initial detection of a rash surrounding her left nipple. Earlier ultrasound and mammography had not indicated pathology. Clinical suspicion and punch biopsies revealed a ductal carcinoma in situ. ...
Source: Tidsskrift for den Norske Laegeforening - March 29, 2023 Category: General Medicine Authors: Claus L ützow-Holm Source Type: research

Pagets sykdom i brystvorten
Tidsskr Nor Laegeforen. 2023 Mar 21;143(5). doi: 10.4045/tidsskr.22.0390. Print 2023 Mar 28.ABSTRACTBACKGROUND: Paget's disease of the nipple comprises approximately 1 % of all breast cancers, and presents with unilateral eczematoid changes to the nipple, areola or surrounding skin. Symptoms can be pain, itching or stinging in the area.CASE PRESENTATION: A female patient in her sixties presented to the skin clinic 18 months after initial detection of a rash surrounding her left nipple. Earlier ultrasound and mammography had not indicated pathology. Clinical suspicion and punch biopsies revealed a ductal carcinoma in situ. ...
Source: Tidsskrift for den Norske Laegeforening - March 29, 2023 Category: General Medicine Authors: Claus L ützow-Holm Source Type: research

Pagets sykdom i brystvorten
Tidsskr Nor Laegeforen. 2023 Mar 21;143(5). doi: 10.4045/tidsskr.22.0390. Print 2023 Mar 28.ABSTRACTBACKGROUND: Paget's disease of the nipple comprises approximately 1 % of all breast cancers, and presents with unilateral eczematoid changes to the nipple, areola or surrounding skin. Symptoms can be pain, itching or stinging in the area.CASE PRESENTATION: A female patient in her sixties presented to the skin clinic 18 months after initial detection of a rash surrounding her left nipple. Earlier ultrasound and mammography had not indicated pathology. Clinical suspicion and punch biopsies revealed a ductal carcinoma in situ. ...
Source: Tidsskrift for den Norske Laegeforening - March 29, 2023 Category: General Medicine Authors: Claus L ützow-Holm Source Type: research

Pagets sykdom i brystvorten
Tidsskr Nor Laegeforen. 2023 Mar 21;143(5). doi: 10.4045/tidsskr.22.0390. Print 2023 Mar 28.ABSTRACTBACKGROUND: Paget's disease of the nipple comprises approximately 1 % of all breast cancers, and presents with unilateral eczematoid changes to the nipple, areola or surrounding skin. Symptoms can be pain, itching or stinging in the area.CASE PRESENTATION: A female patient in her sixties presented to the skin clinic 18 months after initial detection of a rash surrounding her left nipple. Earlier ultrasound and mammography had not indicated pathology. Clinical suspicion and punch biopsies revealed a ductal carcinoma in situ. ...
Source: Tidsskrift for den Norske Laegeforening - March 29, 2023 Category: General Medicine Authors: Claus L ützow-Holm Source Type: research

Pagets sykdom i brystvorten
Tidsskr Nor Laegeforen. 2023 Mar 21;143(5). doi: 10.4045/tidsskr.22.0390. Print 2023 Mar 28.ABSTRACTBACKGROUND: Paget's disease of the nipple comprises approximately 1 % of all breast cancers, and presents with unilateral eczematoid changes to the nipple, areola or surrounding skin. Symptoms can be pain, itching or stinging in the area.CASE PRESENTATION: A female patient in her sixties presented to the skin clinic 18 months after initial detection of a rash surrounding her left nipple. Earlier ultrasound and mammography had not indicated pathology. Clinical suspicion and punch biopsies revealed a ductal carcinoma in situ. ...
Source: Tidsskrift for den Norske Laegeforening - March 29, 2023 Category: General Medicine Authors: Claus L ützow-Holm Source Type: research

Pagets sykdom i brystvorten
Tidsskr Nor Laegeforen. 2023 Mar 21;143(5). doi: 10.4045/tidsskr.22.0390. Print 2023 Mar 28.ABSTRACTBACKGROUND: Paget's disease of the nipple comprises approximately 1 % of all breast cancers, and presents with unilateral eczematoid changes to the nipple, areola or surrounding skin. Symptoms can be pain, itching or stinging in the area.CASE PRESENTATION: A female patient in her sixties presented to the skin clinic 18 months after initial detection of a rash surrounding her left nipple. Earlier ultrasound and mammography had not indicated pathology. Clinical suspicion and punch biopsies revealed a ductal carcinoma in situ. ...
Source: Tidsskrift for den Norske Laegeforening - March 29, 2023 Category: General Medicine Authors: Claus L ützow-Holm Source Type: research

Local recurrence of breast cancer histologically resembling Paget disease presumably due to needle tract seeding: a case report
AbstractSeeding of cancer cells along the needle tract during core needle biopsy is a well-known phenomenon, with a reported frequency of between 22 and 50% [Hoorntje et al. in Eur J Surg Oncol 30:520 –525, 2004;Liebens et al. in Maturitas 62:113–123, 2009;Diaz et al. in AJR Am J Roentgenol 173:1303–1313, 1999;]. Local recurrence due to needle tract seeding is rare because the immune system eliminates the cancer cells in most cases. In addition, most local recurrences due to needle tract se eding occur as invasive carcinoma after diagnosis of invasive ductal carcinoma of the breast or mucinous carcinoma, and needle t...
Source: International Cancer Conference Journal - February 20, 2023 Category: Cancer & Oncology Source Type: research

Breast MRI: Clinical Indications, Recommendations, and Future Applications in Breast Cancer Diagnosis
This article aims to provide an updated overview of the indications for diagnostic breast magnetic resonance imaging (MRI), discusses the available and novel imaging exams proposed for breast cancer detection, and discusses considerations when performing breast MRI in the clinical setting.Recent FindingsBreast MRI is superior in identifying lesions in women with a very high risk of breast cancer or average risk with dense breasts. Moreover, the application of breast MRI has benefits in numerous other clinical cases as well; e.g., the assessment of the extent of disease, evaluation of response to neoadjuvant therapy (NAT), ...
Source: Current Oncology Reports - February 7, 2023 Category: Cancer & Oncology Source Type: research

Clinically guided core biopsy and cutaneous punch biopsy in the evaluation of breast lesions: a necessary test or an obsolete skill?
ConclusionClinical core and cutaneous punch biopsies remain a valuable tool in the diagnosis of breast cancer particularly in the management of clinically suspicious radiographically occult malignancies. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - February 1, 2023 Category: General Medicine Source Type: research

Paget's disease of the breast: diagnosis and management
Br J Hosp Med (Lond). 2023 Jan 2;84(1):1-8. doi: 10.12968/hmed.2022.0439. Epub 2023 Jan 24.ABSTRACTPaget's disease of the breast typically affects postmenopausal women and is associated with an underlying malignancy. Skin changes are a common presenting symptom, as well as a lump, nipple discharge, pain and changes to the nipple shape. Imaging options include ultrasound for women under the age of 35 years or mammogram and ultrasound for women over the age of 40 years. The definitive diagnostic investigation is a tissue core biopsy. Cases are discussed by a multidisciplinary team to decide on the optimal management strategy...
Source: British Journal of Hospital Medicine - January 28, 2023 Category: Internal Medicine Authors: Sarah Hudson-Phillips Kofi Cox Puja Patel Wail Al Sarakbi Source Type: research

Paget's disease of the breast: diagnosis and management
Br J Hosp Med (Lond). 2023 Jan 2;84(1):1-8. doi: 10.12968/hmed.2022.0439. Epub 2023 Jan 24.ABSTRACTPaget's disease of the breast typically affects postmenopausal women and is associated with an underlying malignancy. Skin changes are a common presenting symptom, as well as a lump, nipple discharge, pain and changes to the nipple shape. Imaging options include ultrasound for women under the age of 35 years or mammogram and ultrasound for women over the age of 40 years. The definitive diagnostic investigation is a tissue core biopsy. Cases are discussed by a multidisciplinary team to decide on the optimal management strategy...
Source: British Journal of Hospital Medicine - January 28, 2023 Category: Internal Medicine Authors: Sarah Hudson-Phillips Kofi Cox Puja Patel Wail Al Sarakbi Source Type: research

Paget's disease of the breast: diagnosis and management
Br J Hosp Med (Lond). 2023 Jan 2;84(1):1-8. doi: 10.12968/hmed.2022.0439. Epub 2023 Jan 24.ABSTRACTPaget's disease of the breast typically affects postmenopausal women and is associated with an underlying malignancy. Skin changes are a common presenting symptom, as well as a lump, nipple discharge, pain and changes to the nipple shape. Imaging options include ultrasound for women under the age of 35 years or mammogram and ultrasound for women over the age of 40 years. The definitive diagnostic investigation is a tissue core biopsy. Cases are discussed by a multidisciplinary team to decide on the optimal management strategy...
Source: British Journal of Hospital Medicine - January 28, 2023 Category: Internal Medicine Authors: Sarah Hudson-Phillips Kofi Cox Puja Patel Wail Al Sarakbi Source Type: research

Paget's disease of the breast: diagnosis and management
Br J Hosp Med (Lond). 2023 Jan 2;84(1):1-8. doi: 10.12968/hmed.2022.0439. Epub 2023 Jan 24.ABSTRACTPaget's disease of the breast typically affects postmenopausal women and is associated with an underlying malignancy. Skin changes are a common presenting symptom, as well as a lump, nipple discharge, pain and changes to the nipple shape. Imaging options include ultrasound for women under the age of 35 years or mammogram and ultrasound for women over the age of 40 years. The definitive diagnostic investigation is a tissue core biopsy. Cases are discussed by a multidisciplinary team to decide on the optimal management strategy...
Source: British Journal of Hospital Medicine - January 28, 2023 Category: Internal Medicine Authors: Sarah Hudson-Phillips Kofi Cox Puja Patel Wail Al Sarakbi Source Type: research

Paget's disease of the breast: diagnosis and management
Br J Hosp Med (Lond). 2023 Jan 2;84(1):1-8. doi: 10.12968/hmed.2022.0439. Epub 2023 Jan 24.ABSTRACTPaget's disease of the breast typically affects postmenopausal women and is associated with an underlying malignancy. Skin changes are a common presenting symptom, as well as a lump, nipple discharge, pain and changes to the nipple shape. Imaging options include ultrasound for women under the age of 35 years or mammogram and ultrasound for women over the age of 40 years. The definitive diagnostic investigation is a tissue core biopsy. Cases are discussed by a multidisciplinary team to decide on the optimal management strategy...
Source: British Journal of Hospital Medicine - January 28, 2023 Category: Internal Medicine Authors: Sarah Hudson-Phillips Kofi Cox Puja Patel Wail Al Sarakbi Source Type: research