Insights from the Twittersphere: a cross-sectional study of public perceptions, usage patterns, and geographical differences of tweets discussing cocaine
DiscussionThe findings underscore the significance of cocaine as a current social and political issue, with a predominant focus on political and social denunciation in the majority of tweets. Notably, the study reveals a concentration of tweets from the United States and South American countries, reflecting the high prevalence of cocaine-related disorders and overdose cases in these regions. Alarmingly, the study highlights the trivialization of cocaine consumption on Twitter, accompanied by a misleading promotion of its health benefits, emphasizing the urgent need for targeted interventions and antidrug content on social ...
Source: Frontiers in Psychiatry - March 19, 2024 Category: Psychiatry Source Type: research
“Wanna cry this out real quick?”: an examination of secondary traumatic stress risk and resilience among post-overdose outreach staff in Massachusetts
Post-overdose outreach programs engage overdose survivors and their families soon after an overdose event. Staff implementing these programs are routinely exposed to others ’ trauma, which makes them vulnerable... (Source: Harm Reduction Journal)
Source: Harm Reduction Journal - March 19, 2024 Category: Drugs & Pharmacology Authors: Samantha F. Schoenberger, Emily R. Cummins, Jennifer J. Carroll, Shapei Yan, Audrey Lambert, Sarah M. Bagley, Ziming Xuan, Traci C. Green, Franklin Cook, Amy M. Yule, Alexander Y. Walley and Scott W. Formica Tags: Research Source Type: research
Rapid Identification of Suspected Drug Overdose Deaths by Death Investigators, New Jersey, 2020
We examined the performance of a single-item mandatory radio button implemented into a statewide medical examiner database to identify suspected drug overdose deaths in near-real time.MATERIALS AND METHODS: The New Jersey Office of the Chief State Medical Examiner operates a statewide mandated case management data system to document deaths that fall under the jurisdiction of a medical examiner office. In 2018, the New Jersey Office of the Chief State Medical Examiner implemented a radio button into the case management data system that requires investigators to report whether a death is a suspected drug overdose death. We e...
Source: Public Health Reports - March 18, 2024 Category: International Medicine & Public Health Authors: Karli R Hochstatter Marlon Williams Shanna Latham David Fenton Andrew L Falzon Source Type: research
Leveraging neuroscience education to address stigma related to opioid use disorder in the community: a pilot study
Opioid use disorder (OUD) and overdose deaths are a public health crisis. One contributing factor is stigma towards people who use opioids. We developed and conducted a public-facing, half-day educational event designed to challenge misperceptions about OUD from a contemporary neuroscience perspective. Participants engaged with three different resources on the neurobiology of addiction, and, at the end of the event, they rated its effectiveness. We also collected and compared pre- and post-event composite OUD stigma scales. Participants rated our approach and the overall event as highly effective. Additionally, OUD stigma ...
Source: Frontiers in Psychiatry - March 18, 2024 Category: Psychiatry Source Type: research
Strategies to improve delivery of equitable and evidence-informed care for pregnant and birthing people with a substance use disorder in acute care settings: A scoping review protocol
by Carla King, Gregory Laynor, Jennifer McNeely, Adetayo Fawole, Matthew Lee, Mishka Terplan, Sugy Choi
This protocol outlines a proposed scoping review to characterize evidence on implementation and quality improvement (QI) strategies that aim to improve equitable, evidence-informed care delivery for pregnant and birthing people with substance use disorder (SUD) in acute care. Untreated SUD during pregnancy is associated with an increased risk of overdose and severe maternal morbidity. Acute care settings are one important place to deliver equitable, evidence-informed clinical care. While clinical practice guidelines for...
Source: PLoS One - March 18, 2024 Category: Biomedical Science Authors: Carla King Source Type: research
Association Between Self-Reported Opioid Use and Behavioral/Social Health Characteristics —Arizona, 2020
DiscussionOpioid misuse was found to be associated with poor mental and physical health, increased RTBs, and history of at least two ACEs among Arizona adults in this study. These findings stress the importance of opportunities for targeted prevention in both Arizona adults and youth, including screening for ACEs and RTBs, in early stages of life. (Source: International Journal of Mental Health and Addiction)
Source: International Journal of Mental Health and Addiction - March 18, 2024 Category: Addiction Source Type: research
Magnesium hydride protects against acetaminophen-induced acute kidney injury by inhibiting TXNIP/NLRP3/nf- κb pathway
Ren Fail. 2024 Dec;46(1):2330629. doi: 10.1080/0886022X.2024.2330629. Epub 2024 Mar 17.ABSTRACTAcetaminophen (APAP)-induced acute kidney injury (APAP-AKI) has turned into one of reasons for clinic obtained renal insufficiency. Magnesium hydride (MgH2), as a solid-state hydrogen source, might be potentially applied in clinical practice. The current study aimed to investigate the protective effect of MgH2 against APAP-AKI. The results showed that MgH2 improved renal function and histological injury in mice of APAP-AKI. MgH2 also had protective effects on APAP-induced cytotoxicity in HK-2 cells. In addition, the increased lev...
Source: Renal Failure - March 17, 2024 Category: Urology & Nephrology Authors: Yachen Si Lulu Liu Yinyin Zhang Hongxia Li Tingting Zhao Su Liu Xuejun Sun Jin Cheng Hongtao Lu Source Type: research
Magnesium hydride protects against acetaminophen-induced acute kidney injury by inhibiting TXNIP/NLRP3/nf- κb pathway
Ren Fail. 2024 Dec;46(1):2330629. doi: 10.1080/0886022X.2024.2330629. Epub 2024 Mar 17.ABSTRACTAcetaminophen (APAP)-induced acute kidney injury (APAP-AKI) has turned into one of reasons for clinic obtained renal insufficiency. Magnesium hydride (MgH2), as a solid-state hydrogen source, might be potentially applied in clinical practice. The current study aimed to investigate the protective effect of MgH2 against APAP-AKI. The results showed that MgH2 improved renal function and histological injury in mice of APAP-AKI. MgH2 also had protective effects on APAP-induced cytotoxicity in HK-2 cells. In addition, the increased lev...
Source: Renal Failure - March 17, 2024 Category: Urology & Nephrology Authors: Yachen Si Lulu Liu Yinyin Zhang Hongxia Li Tingting Zhao Su Liu Xuejun Sun Jin Cheng Hongtao Lu Source Type: research
