MicroRNA-34a Promotes Vascular Cellular Senescence and Consequent Calcification
With the growing interest in the accumulation of senescent cells as an important cause of aging, and more funding flowing into this part of the field, researchers are uncovering numerous direct links between cellular senescence and age-related conditions. Senescent cells cause harm to tissues via their inflammatory secretions, the senescence-associated secretory phenotype (SASP). The SASP is damaging, but there are usually too few senescent cells, even in later life, to have a significant effect on tissue dysfunction through their localized actions. There may be exceptions to that rule, but the evidence to date strongly su...
Source: Fight Aging! - July 9, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Cato and the ACLU Join Forces to Protect Philadelphia ’s Supervised Injection Site
Trevor BurrusThe first major federal drug law, the Harrison Narcotics Act, went into effect in 1915. As the federal drug war moves into its second century, we are still faced with an unprecedented opioid crisis that isgetting worse during the current pandemic. Yet while other countries such asPortugal andSwitzerland are approaching the problem with new, more humane ideas, the federal government is stuck in the prohibitionist mindset of the past, which not only doesn ’t work but makes the problem worse. Safehouse is a nonprofit public ‐​health organization that seeks to mitigate the harms of the opioid crisi...
Source: Cato-at-liberty - July 8, 2020 Category: American Health Authors: Trevor Burrus Source Type: blogs

The “Drug Czar” Says Overdose Deaths Were Already Rising Before Pandemic and Now Are Spiking—The Ultimate Blame Belongs to Prohibition
Jeffrey A. SingerWhite House “drug czar” Jim Carroll toldPolitico earlier this week that an Office of National Drug Control Policy analysis finds an 11.4 percent year ‐​over‐​year increase in opioid‐​related overdose deaths during the first four months of 2020. Kentucky has seen a 25 percent increase in overdose deaths during the first four months of this year, and West Virginia saw a 50 percent increase in deaths since the beginning of the year. The data are incomplete at this point, and not all states have reported in.Mr. Carroll attributed much of the increase in the overdose rate to anxie...
Source: Cato-at-liberty - July 1, 2020 Category: American Health Authors: Jeffrey A. Singer Source Type: blogs

Update: Repetitive negative thinking may increase (or perhaps be caused by) Alzheimer ’s pathology
Time for a new edition of SharpBrains’ e‑newsletter, featuring this month 13 research findings, resources and brain teasers for lifelong brain and mental health. #1. “We found that people who exhibited higher repetitive negative thinking patterns experienced more cognitive decline over a four-year period. They also had specific declines in memory (which is an early sign of Alzheimer’s disease), and had more amyloid and tau deposits in their brain … There’s increasing evidence that chronic stress is both harmful to your body – and your brain. But more research is needed to understand this link.” Repetit...
Source: SharpBrains - June 25, 2020 Category: Neuroscience Authors: SharpBrains Tags: Cognitive Neuroscience Education & Lifelong Learning Health & Wellness Technology Alzheimer’s Disease biofeedback brain health Brain Teasers DSM FDA mental health neurotech­nolo­gy noninvasive neurotechnologies noninvasive ne Source Type: blogs

The Best Way To Treat Alcohol And Drug Addiction (M)
Deaths from overdoses of opioids, methadone, cocaine and heroine are at all-time highs in the US. → Support PsyBlog for just $5 per month. Enables access to articles marked (M) and removes ads. → Explore PsyBlog's ebooks, all written by Dr Jeremy Dean: Accept Yourself: How to feel a profound sense of warmth and self-compassion The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic Spark: 17 Steps That Will Boost Your Motivation For Anything Activate: How To Find Joy Again By Changing What You Do (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - June 23, 2020 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Addiction Alcohol subscribers-only Source Type: blogs

Podcast: Is Addiction a Disease?
  What is the link between addiction and mental illness? Is addiction a choice? In today’s Not Crazy podcast, Gabe and Lisa discuss whether addiction should be classified as a disease and whether or not it should require medical treatment. Gabe also shares his personal story of addiction and how it tied in with his bipolar disorder. What’s your take? Tune in for an in-depth discussion which covers every angle of this often controversial topic. (Transcript Available Below) Please Subscribe to Our Show: And We Love Written Reviews!  About The Not Crazy podcast Hosts Gabe Howard is an award-winning writer ...
Source: World of Psychology - June 23, 2020 Category: Psychiatry & Psychology Authors: Not Crazy Podcast Tags: Addiction General Mental Health and Wellness Not Crazy Podcast Recovery Source Type: blogs

Four immediate priorities to flatten the mental distress curve
This article was originally published on The Conversation. Article in Context: Three ways to protect your mental health during –and after– COVID-19 New report: Empowering 8 Billion Minds via Ethical Development and Adoption of Neurotechnologies Infographic on the Digital Brain Health Market 2012–2020 Five reasons the future of brain enhancement is digital, pervasive and (hopefully) bright Ten neurotechnologies about to transform brain enhancement & health 10 highlights from the 2019 SharpBrains Virtual Summit (Source: SharpBrains)
Source: SharpBrains - June 22, 2020 Category: Neuroscience Authors: SharpBrains Tags: Cognitive Neuroscience Education & Lifelong Learning Health & Wellness anxiety clinical depression cognitive-behavioral-therapy crisis mental distress mental health mental health crisis mental health curve telehealth telehealth the Source Type: blogs

A Teen Scientist Is Helping To Solve Mysterious Drug-Related Deaths
Daphne Liu's work could help doctors learn if a drug overdose was accidental or intentional —so they can help people who have problems with drugs before it’s too late.Read  More » (Source: NIDA Drugs and Health Blog)
Source: NIDA Drugs and Health Blog - June 15, 2020 Category: Addiction Source Type: blogs

A Teen Scientist Is Helping To Solve Mysterious Drug-Related Deaths
Daphne Liu's work could help doctors learn if a drug overdose was accidental or intentional—so they can help people who have problems with drugs before it’s too late. Read More » (Source: NIDA Drugs and Health Blog)
Source: NIDA Drugs and Health Blog - June 15, 2020 Category: Addiction Source Type: blogs

Drug Overdose with a Fascinating Arrhythmia
===================================MY Comment by KEN GRAUER, MD (5/28/2020):===================================Today ’s case features another look at a fascinating arrhythmia that Dr. Smith first posted on June 10, 2011. The patient presented to the ED following a drug overdose with oxcarbazepine. Although details of the case beyond this were not available — we ’ll assume this patient was hemodynamically stable at the time the ECG in Figure-1 was recorded.What is the cardiac rhythm in Figure-1?Is there AV block?HOW would you proceed inassessing this arrhythmia?Conside...
Source: Dr. Smith's ECG Blog - June 12, 2020 Category: Cardiology Authors: ECG Interpretation Source Type: blogs

Psychology Around the Net: June 6, 2020
Do we really want to cancel 2020? Earlier this week, a friend of mine shared an Instagram post with me. It wasn’t the usual cheeky meme about quarantine-inspired day drinking or how dogs are the best things ever. It was a post written by Leslie David, a writer and designer and the co-founder of Strand Social, a digital marketing and design agency based in California. I’m not going to wax poetic on how this was just the message I needed to read. I’m just going to leave it here in case it’s just the message you need, too. What if 2020 isn’t cancelled?⁣ What if 2020 is the year we’ve been wai...
Source: World of Psychology - June 6, 2020 Category: Psychiatry & Psychology Authors: Alicia Sparks Tags: Psychology Around the Net black community coronavirus Gaming military quarantine self-compassion toxic childhood Source Type: blogs

Anxiety, Despair, and the Coronavirus Pandemic
Jeffrey A. SingerPublic health interventions entail non ‐​economic as well as economic trade‐​offs. Some trade ‐​offs can involve other aspects of public health.I havewrittenabout how blanket bans on elective medical procedures combine with the fear already infused in the public to cause crucial delays in necessary health care. This adds to human suffering from causes other than the COVID-19 virus. Many people with chronic conditions, particularlychronic pain patients, are disproportionately affected by reduced access to routine care. Then there ’s the dramatic drop ‐​of...
Source: Cato-at-liberty - May 30, 2020 Category: American Health Authors: Jeffrey A. Singer Source Type: blogs

Dangers of Overdosing During Coronavirus Quarantine
During this coronavirus pandemic, there are many risks posed to people who have an addiction....The postDangers of Overdosing During Coronavirus Quarantine appeared first onCliffside Malibu. (Source: Cliffside Malibu)
Source: Cliffside Malibu - May 22, 2020 Category: Addiction Authors: Jaclyn Uloth Tags: Addiction Addiction Recovery addiction treatment aftercare coronavirus covid-19 covid19 drug overdose Source Type: blogs

And now for some good news on health
When it comes to health concerns, the COVID-19 pandemic is top of mind for most people right now. And that’s for good reason. But there is some very good non-COVID health news that may not be getting the attention it deserves. According to the CDC, the rates of six of the top 10 causes of death in this country, which account for about three-quarters of all deaths, have been declining. That’s remarkable. And these improvements are occurring despite an aging population and an obesity epidemic that affects several health conditions. Six positive health trends Let’s look at the trends in these conditions and their rank ...
Source: Harvard Health Blog - May 15, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Cancer Health Health trends Heart Health Source Type: blogs