Evaluation of plasma canine C-reactive protein concentrations in dogs with otitis media, healthy dogs and dogs with chronic otitis externa
CONCLUSION AND CLINICAL RELEVANCE: Plasma CRP concentration is not reliable as a discriminatory tool in cases of otitis, although there is a trend for elevation in cases with more severe disease. However, a larger study may provide a statistically more reliable correlation between the severity of OM and CRP concentrations.PMID:38379189 | DOI:10.1111/vde.13241 (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - February 21, 2024 Category: Veterinary Research Authors: E Buendia P A Germain Source Type: research
Evaluation of plasma canine C-reactive protein concentrations in dogs with otitis media, healthy dogs and dogs with chronic otitis externa
CONCLUSION AND CLINICAL RELEVANCE: Plasma CRP concentration is not reliable as a discriminatory tool in cases of otitis, although there is a trend for elevation in cases with more severe disease. However, a larger study may provide a statistically more reliable correlation between the severity of OM and CRP concentrations.PMID:38379189 | DOI:10.1111/vde.13241 (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - February 21, 2024 Category: Veterinary Research Authors: E Buendia P A Germain Source Type: research
Association of cesarean section and infectious outcomes among infants at 1 year of age: Logistic regression analysis using data of 104,065 records from the Japan Environment and Children ’s Study
ConclusionsThis nationwide cohort study did not find an association between cesarean delivery and CNSI, OM, URTI, LRTI, GI, and UTI. However, further studies are needed to evaluate the role of cesarean delivery in the development of infectious diseases. (Source: PLoS One)
Source: PLoS One - February 21, 2024 Category: Biomedical Science Authors: Hajime Maeda Source Type: research
Ear and hearing health in children
Hearing loss is common in childhood. The most common causes of hearing loss varies by age. In childhood this is most frequently due to Otitis Media with Effusion (OME, also known as ‘glue ear’) or Chronic Suppurative Otitis Media (CSOM)). In adolescence hearing loss can result from exposure to loud noise from environmental causes or personal listening devices. Hearing loss has a significant impact upon the ability to learn, socialize and work. Effective early interventions exist and make a difference to speech, access to education, socialization and employment opportunities. (Source: Paediatrics and Child Health)
Source: Paediatrics and Child Health - February 20, 2024 Category: Pediatrics Authors: Tamsin Holland Brown, Shelly Chadha Tags: Occasional review Source Type: research
Leigh syndrome with developmental regression and ataxia due to a novel splicing variant in the PMPCB gene
We report the first splice site variant in thePMPCB gene in a 39-year old individual who experienced developmental regression and ataxia following otitis media in childhood. A minigene assay confirms this variant results in aberrant splicing and skipping of exon 12. (Source: Journal of Human Genetics)
Source: Journal of Human Genetics - February 19, 2024 Category: Genetics & Stem Cells Source Type: research
Successful Antiviral Treatment for Chronic Adenoiditis Caused by Herpes Virus in a Pediatric Patient: A Case Report
CONCLUSIONS Direct visualization of the postnasal space, with a transoral mirror or 120-degree endoscope, prior to adenoidectomy can aid diagnosis. Adenoiditis may be caused by a wide range of organisms, including herpes virus. Active mucopurulent discharge should raise concern for infection by bacteria, fungi, or virus. Previous research on viral infection of the adenoids have been in asymptomatic patients with presumed latent infection and undergoing elective adenoidectomy. To our knowledge, this is the first paper to report on successful treatment with antiviral medication alone.PMID:38366584 | DOI:10.12659/AJCR.942418 (Source: Herpes)
Source: Herpes - February 17, 2024 Category: Infectious Diseases Authors: Leon Kong Francoise Jean-Louis Duncan L Lamont Source Type: research
Successful Antiviral Treatment for Chronic Adenoiditis Caused by Herpes Virus in a Pediatric Patient: A Case Report
CONCLUSIONS Direct visualization of the postnasal space, with a transoral mirror or 120-degree endoscope, prior to adenoidectomy can aid diagnosis. Adenoiditis may be caused by a wide range of organisms, including herpes virus. Active mucopurulent discharge should raise concern for infection by bacteria, fungi, or virus. Previous research on viral infection of the adenoids have been in asymptomatic patients with presumed latent infection and undergoing elective adenoidectomy. To our knowledge, this is the first paper to report on successful treatment with antiviral medication alone.PMID:38366584 | DOI:10.12659/AJCR.942418 (Source: Herpes)
Source: Herpes - February 17, 2024 Category: Infectious Diseases Authors: Leon Kong Francoise Jean-Louis Duncan L Lamont Source Type: research
Protective Characteristics of Human Breast Milk on Early Childhood Otitis Media: A Narrative Review
Breastfeeding Medicine,Volume 19, Issue 2, Page 73-80, February 2024. (Source: Breastfeeding Medicine)
Source: Breastfeeding Medicine - February 16, 2024 Category: Perinatology & Neonatology Authors: Yarden Tenenbaum Weiss Sharon Ovnat Tamir Omer Globus Tal Marom Source Type: research
Role of Topical Estrogen in Outcomes of Myringoplasty: Does it Really Affect the Results of Graft Success and Hearing Thresholds?
This study was carried out from January 2021 to December 2022 in the Department of Otorhinolaryngology, of a tertiary teaching hospital in North India. Patients were assessed by history, examination, otoscopy, Audiometry, and oto-endoscopy. A total of 88 patients were taken out of which 44 patients underwent myringoplasty in which topical estrogen (estradiol valerate solution) was used, and the remaining 44 patients were taken as controls. Patients were then assessed post-operatively based on Audiometry results and graft uptake status. In the estrogen group successful Graft uptake was in seen 40 (90.9%) patients and failed...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - February 15, 2024 Category: ENT & OMF Source Type: research
Biofilm-mediated infections by multidrug-resistant microbes: a comprehensive exploration and forward perspectives
Arch Microbiol. 2024 Feb 14;206(3):101. doi: 10.1007/s00203-023-03826-z.ABSTRACTA biofilm is a collection of microorganisms organized in a matrix of extracellular polymeric material. Biofilms consist of microbial cells that attach to both surfaces and each other, whether they are living or non-living. These microbial biofilms can lead to hospital-acquired infections and are generally detrimental. They possess the ability to resist the human immune system and antibiotics. The National Institute of Health (NIH) states that biofilm formation is associated with 65% of all microbial illnesses and 80% of chronic illnesses. Addit...
Source: Archives of Microbiology - February 14, 2024 Category: Microbiology Authors: Mai M Zafer Gamal A Mohamed Sabrin R M Ibrahim Soumya Ghosh Charn é Bornman Mahmoud A Elfaky Source Type: research
Immunization with a whole cell vaccine reduces pneumococcal nasopharyngeal density and shedding, and middle ear infection in mice
Vaccine. 2024 Feb 12:S0264-410X(24)00131-2. doi: 10.1016/j.vaccine.2024.01.104. Online ahead of print.ABSTRACTPneumococcal Conjugate Vaccines (PCVs) have substantially reduced the burden of disease caused by Streptococcus pneumoniae (the pneumococcus). However, protection is limited to vaccine serotypes, and when administered to children who are colonized with pneumococci at the time of vaccination, immune responses to the vaccine are blunted. Here, we investigate the potential of a killed whole cell pneumococcal vaccine (WCV) to reduce existing pneumococcal carriage and mucosal disease when given therapeutically to infant...
Source: Vaccine - February 13, 2024 Category: Allergy & Immunology Authors: Jayne Manning Sam Manna Eileen M Dunne Viktoria Bongcaron Casey L Pell Natalie L Patterson Sacha D Kuil Poshmaal Dhar David Goldblatt E Kim Mulholland Paul V Licciardi Roy M Robins-Browne Richard Malley Odilia Wijburg Catherine Satzke Source Type: research
Squamous Cell Carcinoma of the Middle Ear —A Common Tumor at an Uncommon Site
We present a rare case of squamous cell carcinoma of the middle ear which clinically presented as chronic suppurative otitis media.Therefore, clinicians should have a high index of suspicion for clinically refractive cases of otorrhea, otalgia, excess bleeding, and non-responsiveness to treatment. All polyps and granulation tissue in EAC and middle ear should be submitted for histopathological examination especially in cases refractory to treatment. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - February 8, 2024 Category: Cancer & Oncology Source Type: research
Speech, Language, Hearing, and Otopathology Results From the International Smith-Magenis Syndrome Patient Registry
CONCLUSIONS: Significant delays and impairment in speech-language were common, but the majority of those with SMS communicated using speech by age 6 years. Age was a significant factor for some aspects of hearing loss and communication. Neither hearing loss nor otitis media exacerbated language impairment. These results confirm and extend previous findings about the nature of speech, language, hearing, and otopathology in those with SMS.PMID:38324273 | DOI:10.1044/2023_JSLHR-23-00179 (Source: Journal of speech, language, and hearing research : JSLHR)
Source: Journal of speech, language, and hearing research : JSLHR - February 7, 2024 Category: Speech-Language Pathology Authors: Christine Brennan Mara Louise Smith Rachael R Baiduc Liam O'Connor Source Type: research
Hearing Improvement in Tympanoplasty, with and Without Canalplasty
This study included 60 patients with chronic mucosal otitis media with narrow external auditory canal, with moderate to large central perforation, presenting to our institution from September 2019 to August 2021. Group A consisted of 30 patients, who underwent tympanoplasty with canalplasty and Group B consisted of 30 patients, who underwent tympanoplasty without canalplasty. Both the groups were followed up for 3 months, compared and analysed for hearing improvement and graft uptake. The results of our study indicated that Group A achieved 93.3% graft uptake rates compared to group B which achieved 80%. In Group A gain ...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - February 6, 2024 Category: ENT & OMF Source Type: research
Association of iron deficiency with chronic suppurative otitis media in adults
CONCLUSIONS: In adult patients, the incidence of iron deficiency was higher in CSOM patients than in controls. Iron deficiency may be considered a potential risk factor for chronic suppurative otitis media, and serum iron parameters should be evaluated in these CSOM patients and further studies should be conducted to better understand the potential link between iron deficiency and CSOM.PMID:38315117 | DOI:10.1080/00016489.2024.2310013 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - February 5, 2024 Category: ENT & OMF Authors: Jingwen Cao Zixuan Yang Wei Liu Sijing Chen Gaoya Qu Cuiping Zhong Source Type: research
