Pattern of tympanic membrane perforation in a tertiary hospital in Nigeria
Conclusion: Tympanic membrane perforation arises mainly from middle ear infections and traumatic causes. At presentation, size and location of perforation vary which depend on duration of infection or the traumatic causes. (Source: Nigerian Journal of Clinical Practice)
Source: Nigerian Journal of Clinical Practice - August 2, 2018 Category: Rural Health Authors: WA Adegbiji GT Olajide OA Olajuyin F Olatoke CC Nwawolo Source Type: research

Idiopathic, Infectious and Reactive Lesions of the Ear and Temporal Bone
AbstractA number of infectious, inflammatory and idiopathic lesions develop within otologic tissues that may share similar clinical and/or microscopic features. This review first provides a working classification for otitis externa, and then otitis media and includes two recently described entities, eosinophilic otitis media and otitis media with ANCA-associated vasculitis. Next, the microscopic findings of a spectrum of otopathologic conditions are described, including post-inflammatory conditions such as tympanosclerosis and aural polyps, an overview of animate aural foreign body as well as iatrogenic aural foreign body ...
Source: Head and Neck Pathology - August 1, 2018 Category: Pathology Source Type: research

Chronic otitis media with effusion in chronic sinusitis with polyps.
Abstract The relationship between otitis media with effusion (OME) and chronic rhinosinusitis with nasal polyposis (CRSwNP) remains unclear. We conducted a cross-sectional study of 80 consecutively presenting patients-42 males and 38 females, aged 15 to 76 years (median: 48)-who were diagnosed with CRSwNP. Our aim was to ascertain the prevalence of OME in CRSwNP patients, to determine whether the severity of CRSwNP affected OME, and to identify risk factors for OME in CRSwNP patients. The severity of CRSwNP was assessed on the basis of nasal symptoms, endoscopic nasal examinations, and Lund-Mackay staging scores. ...
Source: Ear, Nose and Throat Journal - August 1, 2018 Category: ENT & OMF Authors: Daval M, Picard H, Bequignon E, Bedbeder P, Coste A, Ayache D, Escabasse V Tags: Ear Nose Throat J Source Type: research

Serotypes & penicillin susceptibility of Streptococcus pneumoniae isolated from children admitted to a tertiary teaching hospital in Malaysia.
This study was undertaken to determine the serotype diversity and penicillin susceptibility of S. pneumoniae isolated from paediatric patients in a tertiary teaching hospital in Malaysia. Methods: A total of 125 clinical isolates collected from January 2013 to May 2015 were serotyped using seven sequential multiplex polymerase chain reactions. The susceptibility of these isolates to penicillin was also investigated. Results: Serotypes detected among the isolates were serotypes 3, 6A/B, 6C, 11/A/D/F, 15A/F, 19A, 19F, 23A, 23F, 34. Serotypes 19F and 6A/B were the most prevalent serotypes detected. Most of the S. pn...
Source: Indian J Med Res - August 1, 2018 Category: Research Authors: Subramaniam P, Jabar KA, Kee BP, Chong CW, Nathan AM, de Bruyne J, Thavagnanam S, Chua KH, Md Yusof MY, Teh CSJ Tags: Indian J Med Res Source Type: research

Otitis Media with Effusion in Nasal Polyposis and Outcomes Following Surgery: a Longitudinal Observational Study
Clinical Otolaryngology,Volume 0, Issue ja, -Not available-. (Source: Clinical Otolaryngology)
Source: Clinical Otolaryngology - July 30, 2018 Category: ENT & OMF Authors: Q. Lisan , F. Rubin , P. Bonfils , A. Villeneuve Source Type: research

The efficacy of hesperidin for treatment of acute otitis media
In this experimental study, the effect of hesperidin on the treatment of acute otitis media (AOM) was investigated in an AOM-induced rat model. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - July 30, 2018 Category: ENT & OMF Authors: Erdem Atalay Cetinkaya, Osman Ciftci, Saadet Alan, M. Nam ık Oztanır, Nese Basak Source Type: research

Pneumococcal vaccines
Streptococccus pneumoniae is a major cause of disease and death globally with the highest incidence occurring in children less than 5 and older adults and in low income countries. Development of pneumococcal conjugate vaccination (PCV), against the most common disease-causing serotypes, has been an important advancement in prevention of disease with documented effectiveness for invasive pneumococcal disease, pneumonia and otitis media in countries incorporating the vaccine in their national immunization programs. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - July 27, 2018 Category: Infectious Diseases Authors: G. Rodgers Tags: Type: Invited Presentation Source Type: research

Investigation of biofilm formation in adenoids and middle ear in children with chronic otitis media
Background: Presence of biofilm (BF) chronic otitis media (COM) has been demonstrated in experimental studies of chinchillas and also of tympanostomy tubes in children with refractory otorrhea postimpanostomy. To investigate the presence of BF in the middle ear (ME) of children with COM to which tympanostomy tubes were to be placed (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - July 27, 2018 Category: Infectious Diseases Authors: A. Farinati, A. Garcia Segui, A. Fernandez Nu ñez, E. Mansilla Tags: UMP. 144 Source Type: research

The importance of petrous apex and peri-carotid pneumatisation in subtotal petrosectomy and blind sac closure: a radiological study.
CONCLUSION: The degree of separation of middle-ear air cells from the Eustachian tube or nasopharynx, and the relevant anatomy, are reviewed. This knowledge helps to optimise the outcome of subtotal petrosectomy and blind sac closure. The frequency and process of pneumatisation of the petrous apex, and its connections with the middle ear, have been radiologically confirmed. PMID: 30033885 [PubMed - as supplied by publisher] (Source: Journal of Laryngology and Otology)
Source: Journal of Laryngology and Otology - July 25, 2018 Category: ENT & OMF Tags: J Laryngol Otol Source Type: research

Otologic Findings Based on no Complaints in a Pediatric Examination
Conclusion Any complications and sequelae that may develop due to any pathologies and predominantly infections can be prevented by an early diagnosis, which can be made by means of a simple examination, performed merely with an otoscope. Pediatricians and general practitioners should be in close contact with otorhinolaryngologists regarding the pathologies they identify. [...] Thieme Revinter Publicações Ltda Rio de Janeiro, BrazilArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: International Archives of Otorhinolaryngology)
Source: International Archives of Otorhinolaryngology - July 25, 2018 Category: ENT & OMF Authors: Demir, Emine Topal, Sevgi Atsal, Gorkem Erdil, Mehmet Coskun, Zerrin Ozergin Dursun, Engin Tags: Original Research Source Type: research

Ciprofloxacin Otic Suspension (Otiprio) for Acute Otitis Externa
Date: August 13, 2018 Issue #:  1553Summary:  The FDA has approved a 6% otic suspension formulation of the fluoroquinolone antibiotic ciprofloxacin (Otiprio– Otonomy) for single-dose treatment of acute otitis externa (swimmer's ear) caused byPseudomonas aeruginosa orStaphylococcus aureus in patients≥6 months old.Otiprio was approved earlier for prophylaxis in children with bilateral otitis media with effusion who are undergoing tympanostomy tube placement. (Source: The Medical Letter)
Source: The Medical Letter - July 24, 2018 Category: Drugs & Pharmacology Authors: admin Tags: Ciprodex Ciprofloxacin Dexamethasone Fluoroquinolones Hydrocortisone Neomycin Ocuflox Otiprio Otitis media Pseudomonas aeruginosa Stapylococcus aureus Source Type: research

Enzymatic Hydrolysis of Pneumococcal Capsular Polysaccharide Renders the Bacterium Vulnerable to Host Defense [Cellular Microbiology: Pathogen-Host Cell Molecular Interactions]
This study aimed to evaluate the protective role of a glycoside hydrolase, Pn3Pase, targeting the CPS of type 3 S. pneumoniae, which is one of the most virulent serotypes. We have assessed the ability of Pn3Pase to degrade the capsule on a live type 3 strain. Through in vitro assays, we observed that Pn3Pase treatment increases the bacterium's susceptibility to phagocytosis by macrophages and complement-mediated killing by neutrophils. We have demonstrated that in vivo Pn3Pase treatment reduces nasopharyngeal colonization and protects mice from sepsis caused by type 3 S. pneumoniae. Due to the increasing shifts in serotype...
Source: Infection and Immunity - July 23, 2018 Category: Infectious Diseases Authors: Middleton, D. R., Paschall, A. V., Duke, J. A., Avci, F. Y. Tags: Cellular Microbiology: Pathogen-Host Cell Molecular Interactions Source Type: research

The First Case of Chronic Otitis Media due to Kerstersia gyiorum in Korea.
Authors: Kim JH, Lee E, Lee Y PMID: 30027707 [PubMed - in process] (Source: Annals of Laboratory Medicine)
Source: Annals of Laboratory Medicine - July 23, 2018 Category: Laboratory Medicine Tags: Ann Lab Med Source Type: research

Evaluating the ototoxicity of an anti-MRSA peptide KR-12-a2
ConclusionIn our experiment, topically applied KR-12-a2 solution did not cause hearing loss or cochlear damage in guinea pigs. The KR-12-a2 solution can be used as ototopical drops for treating methicillin-resistant staphylococcus aureus otorrhea; however, further evaluations, such as the definition of optimal concentration and combination, are necessary.ResumoIntroduçãoO Staphylococcus aureus resistente à meticilina é um problema emergente não só para a otite média supurativa crônica, mas também para casos de otorreia crônica em crianças com tubo d...
Source: Brazilian Journal of Otorhinolaryngology - July 18, 2018 Category: ENT & OMF Source Type: research

Water protection after tympanostomy (Shepard) tubes does not decrease otorrhea incidence – retrospective cohort study
ConclusionWe found that recommending water protection did not have beneficial effect on the incidence of otorrhea after myringotomy with tubes on chronic otitis media with effusion. However, such measures did not appear to have a negative impact on quality of life. This is a populational observational study with few cases (143 cases); these final statements would be better stated by a very large populational study with another large control group.ResumoIntroduçãoA miringotomia para inserção de tubo de ventilação é a cirurgia otológica mais comum. Otorreia é uma...
Source: Brazilian Journal of Otorhinolaryngology - July 18, 2018 Category: ENT & OMF Source Type: research

Therapeutic approach to pediatric acute mastoiditis – an update
ConclusionsThe main points of the management protocol are: initiate a broad-spectrum intravenous antibiotic treatment; mastoidectomy should be performed if the infection fails to be controlled after 48 h of administering intravenous antibiotic therapy. We believe that early mastoidectomy prevents serious complications, and our initial observation is that by performing broad mastoidectomy with posterior attic and facial recess exposure, recurrence of acute mastoiditis can be prevented.ResumoIntroduçãoA mastoidite aguda continua sendo a complicação mais comum da otite média aguda. Pode...
Source: Brazilian Journal of Otorhinolaryngology - July 18, 2018 Category: ENT & OMF Source Type: research

Prevalence of middle ear abnormalities from otitis media in relation with pneumococcal vaccine use in the Inuit population of Nunavik, province of Quebec, Canada.
CONCLUSIONS: Pneumococcal conjugate vaccination was associated with a decreased frequency of middle ear abnormalities although no effect was seen for major abnormalities which may be trigger by OM with early onset. Clinicaltrials.gov registration number: NCT01694329. PMID: 30026032 [PubMed - as supplied by publisher] (Source: Vaccine)
Source: Vaccine - July 16, 2018 Category: Allergy & Immunology Authors: Le Meur JB, Ayukawa H, Proulx JF, De Wals P Tags: Vaccine Source Type: research

Implementation and results of a surgical training programme for chronic suppurative otitis media in Cambodia.
CONCLUSION: The training programme has demonstrated success, as measured by surgeon confidence and operative outcomes. This approach can be emulated in other settings to help combat the global burden of chronic suppurative otitis media. PMID: 29998817 [PubMed - as supplied by publisher] (Source: Journal of Laryngology and Otology)
Source: Journal of Laryngology and Otology - July 13, 2018 Category: ENT & OMF Tags: J Laryngol Otol Source Type: research

Role of Electronystagmography in Diagnosis of Secondary BPPV in Elderly Patients with Vertigo: A Retrospective Study
This study was undertaken to study occurrence of secondary BPPV utilizing various parameters of ENG. The study group comprised of 131 patients from the neuro-otology proforma data base at ENT centre and vertigo clinic from January 2015 to December 2017. Inclusion criterion was male and female aged 51  years and above presenting with dizziness, imbalance, rotational vertigo, unsteadiness as the chief complaint. Exclusion criterion was BPPV relieved after Epley’s maneuver, Otitis externa, acute Otitis media, Suppurative Otitis media, pre existing neurological condition and history of ear surger y. Neuro-otology Da...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - July 13, 2018 Category: ENT & OMF Source Type: research

Novel Design and Validation of a Micro Instrument in an Ear Grommet Insertion Device
An automated surgical device, the ventilator tube applicator (VTA), enables a grommet insertion surgery for patients with otitis media with effusion (OME) to be completed in a short time automatically and precisely, eliminating the use of general anesthesia (GA) typically required in such procedure. However, its current design limits the usefulness of the device as it is restricted by the properties of the tympanic membrane (TM), such as angle, thickness, and strength. Therefore, a novel design was conceptualized and the insertion control algorithm was improved to overcome the current challenges of the VTA. This innovative...
Source: Journal of Medical Devices, Transactions of the ASME - July 13, 2018 Category: Medical Devices Source Type: research

Individualized Learning Plan (ILP) Is an Effective Tool in Assessing Achievement of Otology-related Subcompetency Milestones
Conclusion: The ILP is an effective tool in measuring residents’ achievement of otology-related milestones, and could possibly be used to supplement or replace faculty assessment. The ILP provides valuable information on barriers to achieving milestones and informs trainees on how to set attainable goals as they pertain to patient care and medical knowledge in otology. (Source: Otology and Neurotology)
Source: Otology and Neurotology - July 11, 2018 Category: ENT & OMF Tags: Research Methodology Source Type: research

Retrospective Analysis of Hearing-Impaired Adult Patients Treated With an Active Transcutaneous Bone Conduction Implant
Conclusion: The tBCI clearly improves speech intelligibility in patients with conductive or mixed hearing loss, showing stable results up to 1 year post-implantation. (Source: Otology and Neurotology)
Source: Otology and Neurotology - July 11, 2018 Category: ENT & OMF Tags: Prosthetic Devices Source Type: research

Intracochlear Pressures in Simulated Otitis Media With Effusion: A Temporal Bone Study
Conclusion: Simulating effusion leads to a frequency-dependent reduction in intracochlear sound pressure levels consistent with audiological presentation and prior reports. Results reveal that intracochlear pressure measurements (PSV and PST) decrease less than expected, and less than the decrease in PDiff. The observed decrease in umbo velocity is greater than in the differential intracochlear pressures, suggesting that umbo velocity overestimates the induced conductive hearing loss. These results suggest that an alternate sound conduction pathway transmits sound to the inner ear during effusion. (Source: Otology and Neurotology)
Source: Otology and Neurotology - July 11, 2018 Category: ENT & OMF Tags: Basic Science Source Type: research

Povidone iodine soaked gelfoam for the treatment of recalcitrant otomycosis – Our experiences at a tertiary care teaching hospital of eastern India
ConclusionUse of the povidone iodine soaked gelfoam at the external auditory canal in recalcitrant otomycosis is an effective and well-tolerated treatment. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - July 11, 2018 Category: Biology Source Type: research

Expression and purification of pneumococcal surface protein a of clade 4 in Escherichia coli using hydroxylapatite and ion-exchange column chromatography
In this study, we describe a simple method to produce PspA of clade 4 from an Escherichia coli expression system using hydroxylapatite and ion-exchange chromatography. Using this method, we successfully expressed soluble PspA4 in 10 L of autoinducing culture medium, with a wet-cell yield of 19 g/L and a final PspA4 concentration of 22.8 mg/L. Additionally, we improved PspA4 purity from 17% to 70% in a single step through the use of hydroxylapatite, resulting in acquisition of recombinant PspA4 (>95% purity) at a final yield of 43% from the starting cell-lysis solution. We subsequently verified the secondary struct...
Source: Protein Expression and Purification - July 11, 2018 Category: Biochemistry Source Type: research

Group A streptococcus acute otitis media progressing to neuroinvasive disease in adults
We describe two such cases from a single institution in Rhode Island in 2017. The clinical presentation, neuroimaging and management are reviewed. The mechanism of intracranial spread may have involved dehiscence of the bony tegmen of the roof of the middle ear cavity. (Source: IDCases)
Source: IDCases - July 10, 2018 Category: Infectious Diseases Source Type: research

A case of cleft lip and palate associated with unilateral choanal atresia
Publication date: Available online 2 July 2018Source: Journal of Oral and Maxillofacial Surgery, Medicine, and PathologyAuthor(s): Yuko Fujihara, Shu Kikuta, Madoka Sugiyama, Keigo Kubota, Makiko Ishibashi, Masaki Igarashi, Hideto Saijo, Kazuto HoshiAbstractChoanal atresia is a congenital anomaly of narrowing or obliteration at posterior nasal aperture, blocking the posterior nasal cavity from the nasopharynx. The incidence of choanal atresia is one in 5,000–8,000 births. It can be bilateral or unilateral, and unilateral choanal atresia is rarely associated with other malformations compared with bilateral choanal atr...
Source: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology - July 10, 2018 Category: ENT & OMF Source Type: research

Animal models of acute otitis media – A review with practical implications for laboratory research
Publication date: June 2018Source: European Annals of Otorhinolaryngology, Head and Neck Diseases, Volume 135, Issue 3Author(s): N.H. Davidoss, Y.K. Varsak, P.L. Santa MariaAbstractConsiderable animal research has focused on developing new strategies for the prevention and treatment of acute otitis media (AOM). Several experimental models of AOM have thus been developed. A PubMed search of the English literature was conducted from 1975 to July 2016 using the search terms “animal model” and “otitis media” from which 91 published studies were included for analysis, yielding 123 animal models. The rat,...
Source: European Annals of Otorhinolaryngology, Head and Neck Diseases - July 10, 2018 Category: ENT & OMF Source Type: research

How to avoid the inappropriate use of antibiotics in upper respiratory tract infections? A position statement from an expert panel
ConclusionsPeriodic revisions on guidelines and recommendations for treatment of the main acute infections are necessary to orient rationale and appropriate use of antibiotics. Continuous medical education and changes in physicians’ and patients’ behavior are required to modify the paradigm that all upper respiratory infection needs antibiotic therapy, minimizing the consequences of its inadequate and inappropriate use.ResumoIntroduçãoA resistência bacteriana a antibióticos nos processos infecciosos é um fato crescente nos últimos anos, especialmente devido ao seu uso in...
Source: Brazilian Journal of Otorhinolaryngology - July 10, 2018 Category: ENT & OMF Source Type: research

Comparison between clinical and audiological results of tympanoplasty with modified sandwich technique and underlay technique
ConclusionDouble layered graft with drum-malleus as a ‘meat’ of sandwich maintains a perfect balance between sufficient stability and adequate acoustic sensitivity.ResumoIntroduçãoO reparo cirúrgico da membrana timpânica, denominado timpanoplastia tipo 1, é uma modalidade de tratamento já bem estabelecida. As técnicas overlay ou underlay de timpanoplastia são comuns. A timpanoplastia pela técnica “sanduíche” é a técnica de enxerto de membrana timpânica overlay e underlay combinadas.ObjetivoDescrever e avaliar a ...
Source: Brazilian Journal of Otorhinolaryngology - July 10, 2018 Category: ENT & OMF Source Type: research

Role of preoperative air-bone gap in tinnitus outcome after tympanoplasty for chronic otitis media with tinnitus
Publication date: March–April 2018Source: Brazilian Journal of Otorhinolaryngology, Volume 84, Issue 2Author(s): Hong Chan Kim, Chul Ho Jang, Young Yoon Kim, Jong Yuap Seong, Sung Hoon Kang, Yong Beom ChoAbstractIntroductionPrevious reports indicated that middle ear surgery might partially improve tinnitus after surgery. However, until now, no influencing factor has been determined for tinnitus outcome after middle ear surgery.ObjectiveThe purpose of this study was to investigate the association between preoperative air-bone gap and tinnitus outcome after tympanoplasty type I.MethodsSeventy-five patients with tinnitu...
Source: Brazilian Journal of Otorhinolaryngology - July 10, 2018 Category: ENT & OMF Source Type: research

Functional and Anatomical Outcome of Inside Out Technique For Cholesteatoma Surgery
Publication date: July–August 2018Source: American Journal of Otolaryngology, Volume 39, Issue 4Author(s): Priyanka Chamoli, Chandra Veer Singh, Sheetal Radia, Anand K. ShahAbstractBackgroundTo study the efficacy of inside-out technique in completely eradicating the cholesteatoma from middle ear and mastoid, preservation of hearing & and quality of life post mastoidectomy with regards to recurrent discharge, wax, granulations.Material and methodsNon-randomized, prospective, observational study performed at the Department of ENT in our hospital. In the study we included 100 patients presenting with chronic suppura...
Source: American Journal of Otolaryngology - July 10, 2018 Category: Endocrinology Source Type: research

Effects of combination of balloon Eustachian tuboplasty with methylprednisolone irrigation on treatment of chronic otitis media with effusion in adults
This study was to investigate the pathological changes of Eustachian tube mucosa and optimized treatment.Materials and methodsRetrospective study of four groups: I: tympanic paracentesis, II: balloon Eustachian tuboplasty (BET), III: BET plus tympanic paracentesis, IV: BET and tympanic paracentesis with methylprednisolone irrigation. Biopsy of Eustachian tube mucosa was obtained preoperative and 1 month post. Recurrence ratio and Eustachian tube scores (ETS) were used to evaluate the effect of treatments.ResultsAll patients showed narrowed with edematous and thickened Eustachian tube mucosa. At 1 month post-treatment, ...
Source: American Journal of Otolaryngology - July 10, 2018 Category: Endocrinology Source Type: research

Characteristics of laryngopharyngeal reflux in patients with chronic otitis media
ConclusionsMost patients with chronic otitis media had LPR simultaneously. The LPR in these patients manifested mainly by a positive RFS under a laryngoscope and not by symptoms of the larynx and pharynx. This suggests that LPR may be an important factor in the pathogenesis of COM and anti-reflux treatment may play a significant role in the management of chronic otitis media. (Source: American Journal of Otolaryngology)
Source: American Journal of Otolaryngology - July 10, 2018 Category: Endocrinology Source Type: research

The association between otogenic lateral sinus thrombosis and thrombophilia – A long-term follow-up
ConclusionsPediatric OLST secondary to acute otitis media and mastoiditis may reflect an underlying thrombophilia. Laboratory work-up for thrombophilia should be performed, and anticoagulant treatment may be warranted in managing these patients. (Source: American Journal of Otolaryngology)
Source: American Journal of Otolaryngology - July 10, 2018 Category: Endocrinology Source Type: research

Bioglass reconstruction of posterior meatal wall after canal wall down mastoidectomy
ConclusionSurgical reconstruction of the PMW using BAG that operatively fashioned immediately after CWD mastoidectomy appears to be reliable without considerable complications giving smooth appearance of the PMW and improving the hearing. (Source: American Journal of Otolaryngology)
Source: American Journal of Otolaryngology - July 10, 2018 Category: Endocrinology Source Type: research

Response to comment: Eustachian tube diameter: Is it associated with chronic otitis media development?
Publication date: May–June 2018Source: American Journal of Otolaryngology, Volume 39, Issue 3Author(s): Ceki Paltura, Tuba Selçuk Can, Behice Kaniye Yılmaz, Mehmet Emre Dinç, Ömer Necati Develioğlu, Mehmet Külekçi (Source: American Journal of Otolaryngology)
Source: American Journal of Otolaryngology - July 10, 2018 Category: Endocrinology Source Type: research

Anatomical anomalies of the Eustachian tube and chronic otitis media
Publication date: May–June 2018Source: American Journal of Otolaryngology, Volume 39, Issue 3Author(s): Zhengcai Lou, Zihan Lou (Source: American Journal of Otolaryngology)
Source: American Journal of Otolaryngology - July 10, 2018 Category: Endocrinology Source Type: research

An evidence based protocol for managing neonatal middle ear effusions in babies who fail newborn hearing screening
ConclusionsAn effective initial management plan for children with suspected middle ear pathology and failed NBHS is diagnostic operative microscopy with placement of a ventilation tube in the presence of a MEE along with either intra-operative ABR or close follow-up ABR. This allows for the identification and treatment of babies with a conductive component due to OME, accurate diagnosing of an underlying SNHL component and for prompt aural rehabilitation. (Source: American Journal of Otolaryngology)
Source: American Journal of Otolaryngology - July 10, 2018 Category: Endocrinology Source Type: research

The short- and long-term adverse effects of FGF-2 on tympanic membrane perforations.
This study suggests that the topical application of fibroblast growth factor-2 to human traumatic tympanic membranes is safe. Otorrhoea was the most common short-term side-effect; other less common side-effects included otitis media with effusion and reperforation. No serious long-term side-effects were found. PMID: 29984804 [PubMed - in process] (Source: Acta Otorhinolaryngologica Italica)
Source: Acta Otorhinolaryngologica Italica - July 10, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Pituitary size alteration and adverse effects of radiation therapy performed in 9 dogs with pituitary-dependent hypercortisolism
In conclusion, RT is effective to reduce pituitary size and the mass effect, but does not appear to affect blood hormone concentrations, necessitating additional medical treatment against hypercortisolism. Periodic MRI imaging post-RT enables early detection of adverse effects of RT. (Source: Research in Veterinary Science)
Source: Research in Veterinary Science - July 10, 2018 Category: Veterinary Research Source Type: research

Acute otitis media caused by Streptococcus pneumoniae serotype 19A ST320 clone: epidemiological and clinical characteristics
Publication date: June 2018Source: Journal of Microbiology, Immunology and Infection, Volume 51, Issue 3Author(s): Hsin Chi, Nan-Chang Chiu, Fu-Yuan Huang, Chyong-Hsin Hsu, Kuo-sheng Lee, Li-Min Huang, Yu-Chia HsiehAbstractBackgroundStreptococcus pneumoniae serotype 19A ST320, a highly multiresistant and virulent clone, has emerged as a common pathogen causing acute otitis media (AOM) in children.MethodsPatients aged 0–18 years with AOM who presented at Mackay Memorial Hospital, Taipei, Taiwan were prospectively enrolled between December 1, 2009, and November 30, 2012. For each patient, a specimen of middle-ear fluid...
Source: Journal of Microbiology, Immunology and Infection - July 10, 2018 Category: Microbiology Source Type: research

Otitis media – Definition, Pathogenese, Klinik, Diagnose und Therapie
Laryngo-Rhino-Otol 2018; 97: 497-508 DOI: 10.1055/s-0044-101327Unter dem Begriff Otitis media werden die akute Otitis media, die rezidivierende akute Otitis media, die Otitis media mit Erguss, die chronische Otitis media mesotympanalis und die chronische Otitis media epitympanalis, das Cholesteatom, zusammengefasst. Es handelt sich um vielfältige Krankheitsbilder, die teils ineinander übergehen können und eine individuell angepasste, zielgerichtete Therapie erfordern. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  | &nbs...
Source: Laryngo- Rhino- Otologie - July 9, 2018 Category: ENT & OMF Authors: Leichtle, A. Hoffmann, T.K. Wigand, M.C. Tags: CME-Fortbildung Source Type: research

Advantages of Breastfeeding During Acute Infections: What The Evidence Says
AbstractPurpose of ReviewBreastfeeding has been studied for its multiple benefits to both, the infant and the mother. This review aims to expose the benefits of breastfeeding during acute infections, the main cause of morbidity in infants.Recent FindingsBreastfeeding has the ability to modify the infant ’s microbiome, and consequently its immune system. It also protects against viral infections mainly due to oligosaccharides. The longer the duration of breastfeeding, the greater the benefits (benefits have been observed up to 4 years after).SummaryIt has been shown that breastfeeding provides greater benefits wh...
Source: Current Tropical Medicine Reports - July 7, 2018 Category: Tropical Medicine Source Type: research

A case of cleft lip and palate associated with unilateral choanal atresia
Publication date: Available online 2 July 2018Source: Journal of Oral and Maxillofacial Surgery, Medicine, and PathologyAuthor(s): Yuko Fujihara, Shu Kikuta, Madoka Sugiyama, Keigo Kubota, Makiko Ishibashi, Masaki Igarashi, Hideto Saijo, Kazuto HoshiAbstractChoanal atresia is a congenital anomaly of narrowing or obliteration at posterior nasal aperture, blocking the posterior nasal cavity from the nasopharynx. The incidence of choanal atresia is one in 5,000–8,000 births. It can be bilateral or unilateral, and unilateral choanal atresia is rarely associated with other malformations compared with bilateral choanal atr...
Source: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology - July 6, 2018 Category: ENT & OMF Source Type: research

How to avoid the inappropriate use of antibiotics in upper respiratory tract infections? A position statement from an expert panel
ConclusionsPeriodic revisions on guidelines and recommendations for treatment of the main acute infections are necessary to orient rationale and appropriate use of antibiotics. Continuous medical education and changes in physicians’ and patients’ behavior are required to modify the paradigm that all upper respiratory infection needs antibiotic therapy, minimizing the consequences of its inadequate and inappropriate use.ResumoIntroduçãoA resistência bacteriana a antibióticos nos processos infecciosos é um fato crescente nos últimos anos, especialmente devido ao seu uso in...
Source: Brazilian Journal of Otorhinolaryngology - July 6, 2018 Category: ENT & OMF Source Type: research

Comparison between clinical and audiological results of tympanoplasty with modified sandwich technique and underlay technique
ConclusionDouble layered graft with drum-malleus as a ‘meat’ of sandwich maintains a perfect balance between sufficient stability and adequate acoustic sensitivity.ResumoIntroduçãoO reparo cirúrgico da membrana timpânica, denominado timpanoplastia tipo 1, é uma modalidade de tratamento já bem estabelecida. As técnicas overlay ou underlay de timpanoplastia são comuns. A timpanoplastia pela técnica “sanduíche” é a técnica de enxerto de membrana timpânica overlay e underlay combinadas.ObjetivoDescrever e avaliar a ...
Source: Brazilian Journal of Otorhinolaryngology - July 6, 2018 Category: ENT & OMF Source Type: research

Role of preoperative air-bone gap in tinnitus outcome after tympanoplasty for chronic otitis media with tinnitus
Publication date: March–April 2018Source: Brazilian Journal of Otorhinolaryngology, Volume 84, Issue 2Author(s): Hong Chan Kim, Chul Ho Jang, Young Yoon Kim, Jong Yuap Seong, Sung Hoon Kang, Yong Beom ChoAbstractIntroductionPrevious reports indicated that middle ear surgery might partially improve tinnitus after surgery. However, until now, no influencing factor has been determined for tinnitus outcome after middle ear surgery.ObjectiveThe purpose of this study was to investigate the association between preoperative air-bone gap and tinnitus outcome after tympanoplasty type I.MethodsSeventy-five patients with tinnitu...
Source: Brazilian Journal of Otorhinolaryngology - July 6, 2018 Category: ENT & OMF Source Type: research

Sutureless Tragal Cartilage Island Tympanoplasty: Our Experience
AbstractTo evaluate graft take up and hearing improvement using the technique of tragal cartilage island in COM-mucosal type. Prospective study. A total of 258 type 1 tympanoplasty surgeries were done using tragal cartilage island graft from December 2013, to December 2015; in Jubilee Mission Medical College and Research Institute with a follow up of 1  year. Inclusion criteria—all the patients undergoing type 1 tympanoplasty for chronic otitis media (mucosal type, inactive) with an intact ossicular chain by the senior author. The youngest patient was 6 years old and the oldest was 64 years. This patte...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - July 6, 2018 Category: ENT & OMF Source Type: research

Povidone iodine soaked gelfoam for the treatment of recalcitrant otomycosis – Our experiences at a tertiary care teaching hospital of eastern India
ConclusionUse of the povidone iodine soaked gelfoam at the external auditory canal in recalcitrant otomycosis is an effective and well-tolerated treatment. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - July 6, 2018 Category: Biology Source Type: research