Hematogenous Renal Cell Carcinoma Metastasis in the Postoperative Temporal Bone
We report a case of RCC metastasis to the postoperative temporal bone in the middle of molecular targeted therapy. A 60-year-old man presented left facial palsy with severe retro-auricular pain and he also underwent left middle ear surgery for cholesteatoma more than 30 years before and had been aware of discontinuous otorrhea; therefore, initially we speculated that facial palsy was derived from recurrent cholesteatoma or Ramsay-Hunt syndrome. Exploratory tympanotomy revealed RCC metastasis and postoperative MR indicated hematogenous metastasis. To the best of our knowledge, no report was obtained on temporal bone metasta...
Source: Case Reports in Oncology - February 24, 2017 Category: Cancer & Oncology Source Type: research

Endoscopic tympanoplasty in the treatment of chronic otitis media: our experience.
CONCLUSION: The endoscopy ensures good surgical exposure of hidden areas, frequently sites of residual cholesteatoma. Also, the minimally invasive endoscopic approach is more respectful of anatomy and functionality of the middle ear, restoring and preserving mastoid mucosa, with faster healing time. OBJECTIVES: To investigate the benefits that the systematic use of endoscopy in middle ear surgery has made. STUDY DESIGN: Retrospective cohort studies. METHOD: Two groups of patients were surgically treated for inflammatory diseases of the middle ear. The first group refers to the Pre-Endoscopic period, the seco...
Source: Acta Oto-Laryngologica - February 23, 2017 Category: ENT & OMF Authors: Panetti G, Cavaliere M, Panetti M, Marino A, Iemma M Tags: Acta Otolaryngol Source Type: research

Emergence of Multidrug-Resistant Pneumococcal Serotype 35B among Children in the United States [Bacteriology]
Streptococcus pneumoniae serotype 35B is a nonvaccine serotype associated with high rates of penicillin nonsusceptibility. An increase in the proportion of multidrug-resistant (MDR) 35B isolates has recently been reported. The genetic events contributing to the emergence of MDR serotype 35B are unknown. The sequence type (ST) composition of 78 serotype 35B isolates obtained from pediatric patients with invasive pneumococcal disease from 1994 to 2014 and 48 isolates from pediatric patients with otitis media (noninvasive) from 2011 to 2014 was characterized by multilocus sequence typing (MLST). The most common STs were ST558...
Source: Journal of Clinical Microbiology - February 22, 2017 Category: Microbiology Authors: Olarte, L., Kaplan, S. L., Barson, W. J., Romero, J. R., Lin, P. L., Tan, T. Q., Hoffman, J. A., Bradley, J. S., Givner, L. B., Mason, E. O., Hulten, K. G. Tags: Bacteriology Source Type: research

Pneumolysin induces cellular senescence by increasing ROS production and activation of MAPK/NF- κB signal pathway in glial cells.
Pneumolysin induces cellular senescence by increasing ROS production and activation of MAPK/NF-κB signal pathway in glial cells. Toxicon. 2017 Feb 19;: Authors: Kwon IS, Kim J, Rhee DK, Kim BO, Pyo S Abstract Senescence is an irreversible proliferation arrest that is induced by various stress stimuli including genotoxin. Pneumolysin (PLY) is a pathogenicity factor unique to Streptococcus pneumoniae that is important in pneumococcal-induced diseases such as otitis media, meningitis and pneumonia. However, the cell fate response to the toxin is mechanistically unclear. We investigated the effect o...
Source: Toxicon - February 19, 2017 Category: Toxicology Authors: Kwon IS, Kim J, Rhee DK, Kim BO, Pyo S Tags: Toxicon Source Type: research

Audiological findings in children with mucopolysaccharidoses type i-iv.
CONCLUSIONS: Children with MPS have a high risk of hearing loss. A significant percentage of transmissive HL progressing to mixed or sensorineural HL was observed. This was more common in typesI and II. Periodic follow up of these patients is mandatory because of hearing impairment and consequences for their development and quality of life. PMID: 28223066 [PubMed - as supplied by publisher] (Source: Acta Otorrinolaringologica Espanola)
Source: Acta Otorrinolaringologica Espanola - February 18, 2017 Category: ENT & OMF Authors: Vargas-Gamarra MF, de Paula-Vernetta C, Vitoria Miñana I, Ibañez-Alcañiz I, Cavallé-Garrido L, Alamar-Velazquez A Tags: Acta Otorrinolaringol Esp Source Type: research

Shortened Antimicrobial Treatment for Acute Otitis Media in Young Children
This study compared outcomes of standard duration versus short course antibiotics for AOM. (Source: The Journal of Emergency Medicine)
Source: The Journal of Emergency Medicine - February 17, 2017 Category: Emergency Medicine Authors: Benjamin Li Tags: Abstract Source Type: research

QUESTION 1: What is the risk of a repeat reaction to amoxicillin or a cephalosporin in children with a history of a non-immediate reaction to amoxicillin?
Scenario You are looking after a previously well 4-year-old girl who presents with right ear pain and fever. You diagnose her with otitis media and are about to prescribe her amoxicillin when her parents show you a photo of an urticarial rash that she developed 6 hours after a previous dose of amoxicillin. When counselling the parents you wonder what the risk is of a repeat reaction to (i) amoxicillin or (ii) a cephalosporin? Structured clinical question In a child with a history of a non-immediate reaction (NIR) to amoxicillin (patient) that is rechallenged with the same drug or an oral cephalosporin (intervention), ...
Source: Archives of Disease in Childhood - February 17, 2017 Category: Pediatrics Authors: Grinlington, L., Cranswick, N., Gwee, A. Tags: ADC Archimedes Source Type: research

Quality of life of young patients with recurrent respiratory papillomatosis.
Authors: Montaño-Velázquez BB, Nolasco-Renero J, Parada-Bañuelos JE, Garcia-Vázquez F, Flores-Medina S, García-Romero CS, Jáuregui-Renaud K Abstract OBJECTIVE: To assess quality of life of children and teenagers with recurrent respiratory papillomatosis, according to the evidence of infection by human papillomavirus types 6 and 11, compared with healthy volunteers and patients with chronic otitis media. METHOD: Participants and their parents completed the Pediatric Quality of Life Inventory 4.0. RESULTS: Patients with recurrent respiratory papillomatosis and their p...
Source: Journal of Laryngology and Otology - February 16, 2017 Category: ENT & OMF Tags: J Laryngol Otol Source Type: research

Hearing-Related Health Among Adult American Indians From a Pacific Northwest Tribe
Conclusions Increasing age and significant noise exposure were associated with hearing loss in this tribe. Tinnitus was associated with significant noise exposure and history of otitis media, even after age adjustment. Public health efforts are needed to improve hearing-related health in this tribe through messages about noise exposure and use of hearing protection. (Source: American Journal of Preventive Medicine)
Source: American Journal of Preventive Medicine - February 16, 2017 Category: Global & Universal Source Type: research

Acute Otitis Media During Infancy: Parent-reported Incidence and Modifiable Risk Factors
Conclusions: First-year day care attendance is a major risk factor for AOM symptom episodes among infants in the community. This adjusted effect estimate is higher than previously reported and is age-dependent. AOM prevention strategies in day care facilities should therefore focus in particular on the youngest age groups. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - February 15, 2017 Category: Infectious Diseases Tags: Original Studies Source Type: research

Etiology of Acute Otitis Media in Children Less Than 5 Years of Age: A Pooled Analysis of 10 Similarly Designed Observational Studies
Conclusions: Spn and Hflu remain the leading otopathogens in all populations examined. While associated with overlapping symptoms and severity, they exhibit some differences in their likelihood to cause disease in specific subpopulations. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - February 15, 2017 Category: Infectious Diseases Tags: Original Studies Source Type: research

Impact of Pneumococcal Conjugate Vaccines on Selected Head and Neck Infections in Hospitalized Israeli Children
Conclusion: We observed a reduction in pHNIs incidence after PCV program implementation. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - February 15, 2017 Category: Infectious Diseases Tags: Vaccine Reports Source Type: research

Chronological changes in microbial profiles in external and middle ear diseases: a 20-year study in Korea
AbstractMicrobial infection is one of the most significant causes of ear diseases, but microbial profiles are very diverse according to the diseases and change over time. The purpose of the study was to clarify differences and chronological changes in causative pathogens among infectious ear diseases over the last 20  years, and to identify antibiotic resistance. In total, 1191 isolates were included from patients diagnosed with chronic otitis media without cholesteatoma (COM), cholesteatomatous otitis media (Chole), middle ear effusion (MEE), including acute otitis media and otitis media with effusion, and ext ernal ...
Source: European Archives of Oto-Rhino-Laryngology - February 15, 2017 Category: ENT & OMF Source Type: research

Chronic rhinosinusitis with nasal polyps is associated with chronic otitis media in the elderly
We examined whether CRS was associated with COM in adults who participated in the Korea National Health and Nutrition Examination Survey from 2009 to 2012. A total of 27,492 participants were examined in this cross-sectional epidemiological study. Regression analyses was performed and adjusted for socio-demographics, general health behavior, and other comorbidities. All analyses used complex sampling designs; subgroup analyses were performed according to age, hearing loss, and the presence of cholesteatoma or nasal polyps. The weighted prevalence of COM and CRS was 3.6  ± 0.2 and 6.0 ± 0.2...
Source: European Archives of Oto-Rhino-Laryngology - February 15, 2017 Category: ENT & OMF Source Type: research

Eosinophilic Otitis Media
New England Journal of Medicine,Volume 376, Issue 7, February 2017. (Source: New England Journal of Medicine)
Source: New England Journal of Medicine - February 15, 2017 Category: Internal Medicine Authors: Hugo Lara-S ánchez Luis A. Vallejo Source Type: research

Clinical Manifestations and Genetic Analysis of 17 Patients with Autosomal Dominant Hyper-IgE Syndrome in Mainland China: New Reports and a Literature Review
ConclusionsWe here retrospectively report the largest Chinese cohort of AD-HIES patients with STAT3 mutation. Unique features, when compared to existing literature reports, include (1) later age of diagnosis, (2) significantly higher rate of BCG complications, and (3) lower rate of candidiasis and chronic otitis media. (Source: Journal of Clinical Immunology)
Source: Journal of Clinical Immunology - February 14, 2017 Category: Allergy & Immunology Source Type: research

Role of preoperative air-bone gap in tinnitus outcome after tympanoplasty for chronic otitis media with tinnitus
Publication date: Available online 14 February 2017 Source:Brazilian Journal of Otorhinolaryngology Author(s): Hong Chan Kim, Chul Ho Jang, Young Yoon Kim, Jong Yuap Seong, Sung Hoon Kang, Yong Beom Cho Introduction Previous reports indicated that middle ear surgery might partially improve tinnitus after surgery. However, until now, no influencing factor has been determined for tinnitus outcome after middle ear surgery. Objective The purpose of this study was to investigate the association between preoperative air-bone gap (ABG) and tinnitus outcome after tympanoplasty type I. Methods Seventy-five patients with tinnitus w...
Source: Brazilian Journal of Otorhinolaryngology - February 14, 2017 Category: ENT & OMF Source Type: research

Innovative primary care delivery in rural Alaska: a review of patient encounters seen by community health aides.
CONCLUSIONS: CHA/Ps provide a broad range of primary care in remote Alaskan communities whose residents would otherwise be without consistent medical care. Alaska's CHA/P program could serve as a health-care delivery model for other remote communities with health care access challenges. To access the supplementary material to this article: 'NPIRS Categorical Hierarchy' please see the Supplementary files under Article Tools online. PMID: 28156357 [PubMed - in process] (Source: International Journal of Circumpolar Health)
Source: International Journal of Circumpolar Health - February 8, 2017 Category: Global & Universal Tags: Int J Circumpolar Health Source Type: research

Children in Greenland: disease patterns and contacts to the health care system.
Conclusions In this first study of its kind, the health care contact pattern in Greenlandic children showed a relatively high hospitalisation rate and duration per admission, and a low primary health care contact rate. The overall contact rate and disease pattern resembled those in Denmark, except for tuberculosis screening. Adherence to the vaccination programme was low. These findings may be helpful for the organisation and dimensioning of the Greenlandic health care system for children. PMID: 28156369 [PubMed - in process] (Source: International Journal of Circumpolar Health)
Source: International Journal of Circumpolar Health - February 7, 2017 Category: Global & Universal Tags: Int J Circumpolar Health Source Type: research

To Study the Association of the Size and Site of Tympanic Membrane Perforation with the Degree of Hearing Loss
AbstractChronic suppurative otitis media is a serious health problem worldwide. It has been a general view that the hearing loss increases with the size of the perforation, more so if it is in the postero- inferior quadrant. The present study is an effort to test the validity of above concepts. With Institutional ethical committee clearance, an observational study was carried at SMS medical college, Jaipur. A total of 90 cases were studied. All cases between the age group 15 –50 years with dry tympanic membrane perforations were divided into 3 groups Group I (0–9 mm²), Group II (9–30 m...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - February 7, 2017 Category: ENT & OMF Source Type: research

Can changes in parentally measured acoustic reflectometry levels predict the middle ear status?
Spectral gradient acoustic reflectometry (SG-AR) may be used to detect middle ear effusion. Our aim was to investigate whether increasing SG-AR levels between two SG-AR examinations indicate deterioration from a healthy middle ear to acute otitis media (AOM). (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - February 7, 2017 Category: ENT & OMF Authors: Nora Erkkola-Anttinen, Miia K. Laine, Paula A. T ähtinen, Aino Ruohola Source Type: research

Incidence of Facial Nerve Canal Dehiscence in Primary and Revision Cholesteatoma Surgery
In conclusions we found that there was no difference between primary and revision surgeries regarding the incidence of FCD. Surgeons should consider effective measures to prevent intra-operative facial nerve trauma in COM surgeries. (Source: Indian Journal of Otolaryngology and Head and Neck Surgery)
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - February 6, 2017 Category: ENT & OMF Source Type: research

Adherence to acute otitis media diagnosis and treatment guidelines among Israeli otolaryngologists
The recent Israeli acute otitis media (AOM) guidelines, drafted mainly by pediatricians and family physicians in 2013, addressed diagnostic and therapeutic issues, in order to reduce over-diagnosis and treatment. These guidelines are considered as the 'standard of care' for AOM management. While the adherence rate of pediatricians to previous Israeli AOM guidelines (2004) was reported to be high (>85%), the compliance of otolaryngologists has not been studied. (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - February 6, 2017 Category: ENT & OMF Authors: Tal Marom, Mathan Bobrow, Ephraim Eviatar, Yahav Oron, Sharon Ovnat Tamir Source Type: research

Correction: Risk Factors of Early Otitis Media in the Danish National Birth Cohort
by Asbj ørn Kørvel-Hanquist, Anders Koch, Janni Niclasen, Jesper Dammeyer, Jørgen Lous, Sjurdur Frodi Olsen, Preben Homøe (Source: PLoS One)
Source: PLoS One - February 6, 2017 Category: Biomedical Science Authors: Asbj ørn Kørvel-Hanquist Source Type: research

Purification and Characterization of MicroRNAs within Middle Ear Fluid Exosomes: Implication in Otitis Media Pathophysiology.
CONCLUSION: To our knowledge, this the first report demonstrating the presence of exosomes transporting miRNAs in MEEs. These findings open a broad and novel area of research in OM pathophysiology as driven by miRNA cell communication.Pediatric Research (2017); doi:10.1038/pr.2017.25. PMID: 28157838 [PubMed - as supplied by publisher] (Source: Pediatric Research)
Source: Pediatric Research - February 3, 2017 Category: Pediatrics Authors: Val S, Jeong S, Poley M, Krueger A, Nino G, Brown K, Preciado D Tags: Pediatr Res Source Type: research

Late presentation of egg white and milk protein allergy as rhinitis and otitis media.
PMID: 28165776 [PubMed - in process] (Source: British Journal of Hospital Medicine)
Source: British Journal of Hospital Medicine - February 2, 2017 Category: Internal Medicine Authors: Haywood M, Alade A, Vijendren A, Singh P Tags: Br J Hosp Med (Lond) Source Type: research

Etiology of acute otitis media and serotype distribution of Streptococcus pneumoniae and Haemophilus influenzae in Chilean children
This study estimated the baseline etiology, distribution, and antibiotic susceptibility of bacterial serotypes that causes AOM in children aged (Source: Medicine)
Source: Medicine - February 1, 2017 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Antibiotic prescribing for acute otitis media and acute sinusitis: a cross-sectional analysis of the ReCEnT study exploring the habits of early career doctors in family practice
Conclusion.Early career GPs are not prescribing in an evidence-based manner. The complexity of guidelines for AOM and acute sinusitis may be confusing for prescribers, especially early career doctors struggling with inexperience and diagnostic uncertainty. Educational interventions are necessary to bring prescribing rates closer to quality benchmarks. (Source: Family Practice)
Source: Family Practice - February 1, 2017 Category: Primary Care Source Type: research

Early Childhood Respiratory Infections: How Many Is A Lot?
Investigators from Finland conducted a prospective cohort study to characterize the clinical manifestations, early risk factors, and outcomes of children ≤2 years old with recurrent respiratory infections. Parents of newborns were recruited soon after birth to participate. Enrolled parents were instructed to keep daily diaries of respiratory symptoms of their child until age 2 years; parents also recorded physician visits with diagnoses and treatment, as well as absences of the child from daycare or the parent from work. Demographic information was collected at enrollment and updated at the child’s age of 13, 18, ...
Source: AAP Grand Rounds - February 1, 2017 Category: Pediatrics Authors: Lesser, D. Tags: General Pediatrics Source Type: research

The endothelial nitric oxide synthase (eNOS) polymorphism in otitis media with effusion (OME)
Conclusion To the best of our knowledge, G allele was identified as predisposing to the development of OME and this is the first report indicates the correlation between the eNOS G894T polymorphism and OME in Turkey. (Source: European Annals of Otorhinolaryngology, Head and Neck Diseases)
Source: European Annals of Otorhinolaryngology, Head and Neck Diseases - February 1, 2017 Category: ENT & OMF Source Type: research

Epidemiology of Otitis Media with Spontaneous Perforation of the Tympanic Membrane in Young Children and Association with Bacterial Nasopharyngeal Carriage, Recurrences and Pneumococcal Vaccination in Catalonia, Spain - The Prospective HERMES Study
by Robert Cilveti, Montserrat Olmo, Josefa P érez-Jove, Juan-José Picazo, Josep-Lluis Arimany, Emiliano Mora, Tomás M. Pérez-Porcuna, Ignacio Aguilar, Aurora Alonso, Francesc Molina, María del Amo, Cristina Mendez, on behalf of the HERMES Study Group The Epidemiology of otitis media with spontaneous perforation of the tympanic membrane and associated nasopharyngeal carriage of bacterial otopathogens was analysed in a county in Catalonia (Spain) with pneumococcal conjugate vaccines (PCVs) not included in the immunization programme at study time . A prospective, multicentre study was perfo...
Source: PLoS One - February 1, 2017 Category: Biomedical Science Authors: Robert Cilveti Source Type: research

Clinical effectiveness of the Sanfu herbal patch at acupoints for respiratory diseases including otitis media in children: A pilot before-and-after study
Conclusion The effectiveness of SHP in preventing the common cold in children seems to be encouraging, but not conclusive, because of the methodological limitations of this study. Well-designed randomized controlled trials are necessary to confirm these findings. For other respiratory diseases, further research recruiting participants separately according to each respiratory disease should be conducted to validate the effects of SHP treatment. (Source: European Journal of Integrative Medicine)
Source: European Journal of Integrative Medicine - February 1, 2017 Category: Complementary Medicine Source Type: research

Australian Aboriginal children with otitis media have reduced antibody titres to specific nontypeable Haemophilus influenzae vaccine antigens.
Abstract Indigenous populations experience high rates of otitis media (OM), with increased chronicity and severity compared to that experienced by their non-Indigenous counterparts. Data are lacking on immune responses to otopathogenic bacteria in these high-risk populations. Non-typeable Haemophilus influenzae (NTHi) is the predominant otopathogen in Australia. Currently no vaccines are licensed to target NTHi, however Protein D (PD) from NTHi is included as a carrier protein in the 10-valent pneumococcal conjugate vaccine PHiD10-CV, and other promising protein vaccine candidates exist, including outer membrane p...
Source: Clinical and Vaccine Immunology - February 1, 2017 Category: Allergy & Immunology Authors: Thornton RB, Kirkham LS, Corscadden KJ, Wiertsema SP, Fuery A, Jones BJ, Coates HL, Vijayasekaran S, Zhang G, Keil A, Richmond PC Tags: Clin Vaccine Immunol Source Type: research

Effectiveness of Type I Tympanoplasty in Wet and Dry Ear in Safe Chronic Suppurative Otitis Media
This study was done in ENT OPD at Tertiary Health Care Institute of Central India. It was conducted from November 2012 to October 2014 on 86 patients having Safe Chronic Suppurative Otitis Media. The patients were divided into two groups as Dry ear group and Wet ear group. Dry ear group included patients whose ear was dry for at least 6  weeks prior to the surgery. Wet ear group included patients who had minimal mucoid discharge in the middle ear which on culture and sensitivity showed no microorganisms. Type 1 Tympanoplasty was done in all patients. Results were analyzed statistically. Complete graft uptake was seen ...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - January 31, 2017 Category: ENT & OMF Source Type: research

Otologic and audiologic findings in 22q11.2 deletion syndrome
In conclusion, hearing loss and otitis media are frequently present in patients with 22q11.2 deletion syndrome. Moreover, our results suggest that children with 22q11.2 deletion syndrome remain susceptible for otitis media as they age. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - January 30, 2017 Category: ENT & OMF Source Type: research

Luc ’s abscess masquerading as severe otitis externa
We report a 12-year old boy who presented with severe otitis externa, complicated by a Luc’s abscess. He underwent incision and drainage of the abscess without mastoidectomy, followed by 6-weeks of culture-directed antibiotic therapy, and re covered well. This case suggests that Luc’s abscess may present as severe otitis externa. It also supports the current literature, that the need for a mastoidectomy may be judged on a case by case basis. (Source: International Journal of Pediatric Otorhinolaryngology Extra)
Source: International Journal of Pediatric Otorhinolaryngology Extra - January 27, 2017 Category: ENT & OMF Authors: Gan Yijin Jereme, Tan Kun Kiaang Henry, Koh Huiting Lynn Tags: Case Report Source Type: research

Luc's abscess masquerading as severe otitis externa
We report a 12-year old boy who presented with severe otitis externa, complicated by a Luc's abscess. He underwent incision and drainage of the abscess without mastoidectomy, followed by 6-weeks of culture-directed antibiotic therapy, and recovered well. This case suggests that Luc's abscess may present as severe otitis externa. It also supports the current literature, that the need for a mastoidectomy may be judged on a case by case basis. (Source: International Journal of Pediatric Otorhinolaryngology Extra)
Source: International Journal of Pediatric Otorhinolaryngology Extra - January 27, 2017 Category: ENT & OMF Authors: Gan Yijin Jereme, Tan Kun Kiaang Henry, Koh Huiting Lynn Tags: Case Report Source Type: research

Antibiotic management of children with infectious diseases in Dutch Primary Care
Conclusion.This detailed insight in antibiotic management of childhood infections shows targets for Dutch improvement strategies: (i) prevent antibiotic prescribing for acute upper RTI and bronchitis; (ii) stimulate the use of narrow-spectrum antibiotics; and (iii) reduce the use of macrolides and amoxicillin/clavulanate. Furthermore, this information is helpful to compare antibiotic policy between countries. (Source: Family Practice)
Source: Family Practice - January 24, 2017 Category: Primary Care Source Type: research

Temporomandibular Joint Disorders as a Cause of Aural Fullness.
Conclusion: TMD as a potential cause of aural fullness should be considered in otolaryngology practice. PMID: 28103655 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - January 22, 2017 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Effect of Mastoid Drilling on Hearing of the Contralateral Normal Ear in Mastoidectomy
AbstractTo evaluate hearing of the contralateral normal ear before and after mastoidectomy in a longitudinal manner and to assess whether the hearing loss is transient or permanent and to find out the duration of temporary hearing loss. This was a clinical longitudinal observational study involving 50 patients with unilateral chronic suppurative otitis media requiring mastoidectomy operation over a period of 18  months after satisfying the inclusion criteria. During the part of the mastoidectomy surgery involving drilling of the mastoid bone, noise levels were recorded at multiple points in the surgery using a digital...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - January 21, 2017 Category: ENT & OMF Source Type: research

The effects of ventilation tubes versus no ventilation tubes for recurrent acute otitis media or chronic otitis media with effusion in 9 to 36  month old Greenlandic children, the SIUTIT trial: study protocol for a randomized controlled trial
The prevalence of otitis media in Greenlandic children is one of the highest in the world. International studies have shown that otitis-prone children may benefit from tubulation of the tympanic membrane. Howe... (Source: Trials)
Source: Trials - January 19, 2017 Category: Journals (General) Authors: Malene N øhr Demant, Ramon Gordon Jensen, Janus Christian Jakobsen, Christian Gluud and Preben Homøe Source Type: research

Cholesteatoma Induced Labyrinthine Fistula: Is Aggressiveness in Removing Disease Justified?
AbstractIssues of complete disease clearance and hearing preservation in cholesteatoma induced labyrinthine fistula cases has been discussed and updated in this article. Successful disease clearance and hearing preservation in a case of cholesteatoma induced isolated cochlear promontory fistula encouraged us to retrospectively analyse 13 more cases of cholesteatoma induced labyrinthine fistula who presented in emergency service as complicated chronic suppurtive otitis media. Pre-operatively nine patients experienced vertigo, two had profound sensori neural hearing loss and radiology was suggestive of labyrinthine fistula i...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - January 19, 2017 Category: ENT & OMF Source Type: research

Innovative Use of Tympanometry and Scintigraphy in Preoperative Assessment of the Patients with Chronic Otitis Media
AbstractNormal middle ear volume indicates the well ventilated middle ear and subsequently the normal function of the Eustachian tube. We carried out preoperative assessment of the middle ear volume by tympanometry and scintigraphic evaluation of Eustachian tube patency in patients with unilateral otitis media. We correlated the middle ear volume and Eustachian tube patency in these patients. Prospective. A total of 58 patients with unilateral otitis media were studied. All patients underwent Eustachian tube scintigraphy. We categorized the patients as Group A with patent Eustachian tube and Group B with blocked Eustachian...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - January 19, 2017 Category: ENT & OMF Source Type: research

Cost-effectiveness of 13-valent pneumococcal conjugate vaccination in Mongolia.
CONCLUSION: Introducing PCV13 as part of Mongolia's national programme appears to be highly cost-effective when compared to no vaccination and cost-saving from a societal perspective at vaccine purchase prices offered through Gavi. Notwithstanding uncertainties around some parameters, cost-effectiveness of PCV introduction for Mongolia remains robust over a range of conservative scenarios. Availability of high-quality national data would improve future economic analyses for vaccine introduction. PMID: 28109706 [PubMed - as supplied by publisher] (Source: Vaccine)
Source: Vaccine - January 18, 2017 Category: Allergy & Immunology Authors: Sundaram N, Chen C, Yoong J, Luvsan ME, Fox K, Sarankhuu A, La Vincente S, Jit M Tags: Vaccine Source Type: research

Microbiology of otitis media in Indigenous Australian children: review.
CONCLUSION: Most studies have used culture-based methods and specimens from middle-ear discharge or the nasopharynx. Findings from these studies are consistent with international literature, but reliance on culture may incorrectly characterise the microbiology of this condition. Advances in genomic technologies are now providing microbiologists with the ability to analyse the entire mixed bacterial communities ('microbiomes') of samples obtained from Indigenous children with otitis media. PMID: 28088924 [PubMed - as supplied by publisher] (Source: Journal of Laryngology and Otology)
Source: Journal of Laryngology and Otology - January 17, 2017 Category: ENT & OMF Tags: J Laryngol Otol Source Type: research

Indicators for continuous quality improvement for otitis media in primary health care for Aboriginal and Torres Strait Islander children
Beverly Sibthorpe, Jason Agostino, Harvey Coates, Sharon Weeks, Deborah Lehmann, Marianne Wood, Francis Lannigan, Daniel McAullay (Source: Australian Journal of Primary Health)
Source: Australian Journal of Primary Health - January 16, 2017 Category: Primary Care Authors: Beverly Sibthorpe Jason Agostino Harvey Coates Sharon Weeks Deborah Lehmann Marianne Wood Francis Lannigan Daniel McAullay Source Type: research

Acute Otitis Media in Children.
PMID: 28084706 [PubMed - in process] (Source: American Family Physician)
Source: American Family Physician - January 15, 2017 Category: Primary Care Authors: Venekamp RP, Damoiseaux RA, Schilder AG Tags: Am Fam Physician Source Type: research

Time-course of Serum Pro-inflammatory Cytokines and Chemokines Levels Observed in Granulomatosis with Polyangiitis: A Case Report.
Authors: Kozu Y, Gon Y, Takano Y, Noguchi T, Hayashi S, Kumasawa F, Mizumura K, Maruoka S, Hashimoto S Abstract A 77-year-old man visited our hospital with chief complaints of difficulty in hearing, nasal discharge and fever. The patients was diagnosed with otitis media, and his fever continued at approximately 38°C despite the administration of clarithromycin. After that, dyspnea on exertion developed and chest X-ray examination indicated multiple infiltrative shadows. PR3-ANCA levels were high (238-fold of the normal levels), and granulomatosis with polyangiitis (GPA) was diagnosed on the basis of clinical sy...
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - January 14, 2017 Category: Respiratory Medicine Tags: Sarcoidosis Vasc Diffuse Lung Dis Source Type: research

Early childhood otitis media and later school performance – A prospective cohort study of associations
Otitis media (OM) is a common disease in childhood and hearing loss (HL) is the most common complication. Prolonged HL may lead to language delay and cognitive difficulties. However, the consequences of HL due to OM are not fully understood.The aim of this study was to determine the possible association between number of OM episodes in childhood and self-rated school performance controlling for potential confounders. (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - January 14, 2017 Category: ENT & OMF Authors: Vincent Fougner, Asbj ørn Kørvel-Hanquist, Anders Koch, Jesper Dammeyer, Janni Niclasen, Jørgen Lous, Preben Homøe Source Type: research