Effects of Maintenance Cabozantinib+BSC Versus BSC in Children and AYA With Osteosarcoma
Conditions: Osteosarcoma; Osteosarcoma in Children; Osteosarcoma in Adolescents and Young Adults Interventions: Drug: Cabozantinib; Other: Best Supportive Care (BSC); Other: Best Supportive Care (BSC) Sponsors: Ipsen Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 2, 2024 Category: Research Source Type: clinical trials

Donor Site Morbidity After Free Vascularized Fibular Graft
Conditions: Osteosarcoma Interventions: Radiation: Xray Sponsors: Assiut University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 22, 2024 Category: Research Source Type: clinical trials

Lisata Therapeutics Announces U.S. FDA Rare Pediatric Disease Designation Granted to LSTA1 for the Treatment of Osteosarcoma
BASKING RIDGE, N.J., March 21, 2024 (GLOBE NEWSWIRE) -- Lisata Therapeutics, Inc. (Nasdaq: LSTA) (“Lisata” or the“Company”), a clinical-stage pharmaceutical company developing innovative therapies for the treatment of... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - March 21, 2024 Category: Pharmaceuticals Source Type: clinical trials

Lisata Therapeutics Announces U.S. FDA Rare Pediatric Disease Designation Granted to LSTA1 for the Treatment of Osteosarcoma
BASKING RIDGE, N.J., March 21, 2024. Lisata Therapeutics, Inc. (“Lisata” or the“Company”), a clinical-stage pharmaceutical company developing innovative therapies for the treatment of advanced solid tumors and other serious... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - March 21, 2024 Category: Pharmaceuticals Source Type: clinical trials

Safety and Feasibility of Intraoperative Visualization With Cytalux in Children
Conditions: Osteosarcoma; Pulmonary Metastasis; Fluorescence; Metastatic Sarcoma; Pediatrics Interventions: Drug: Cytalux Sponsors: Ann& Robert H Lurie Children ' s Hospital of Chicago; On Target Laboratories, LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 31, 2024 Category: Research Source Type: clinical trials

A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs
Conditions: Lung Cancer, Non-small Cell; Lung Cancer Metastatic; Solid Tumor, Adult; Advanced Cancer; Lung Cancer, Small Cell; Metastatic Colorectal Cancer; Metastatic Renal Cell Carcinoma; Metastatic Hepatocellular Carcinoma; Metastatic Sarcoma; Metastatic Osteosarcoma Interventions: Biological: KB707 Sponsors: Krystal Biotech, Inc. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 29, 2024 Category: Research Source Type: clinical trials

Trilaciclib Combined With Chemotherapy for Perioperative Treatment of Osteosarcoma
Conditions: Osteosarcoma Interventions: Drug: Trilaciclib Sponsors: The First Affiliated Hospital of Xinxiang Medical College Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 22, 2024 Category: Research Source Type: clinical trials

Evaluation of Prophylactic Photobiomodulation Therapy in Patients With Osteosarcoma
Conditions: Mucositis Oral Interventions: Other: Preventive photobiomodulation Therapy (PBMT) Sponsors: Instituto Nacional de Cancer, Brazil Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 22, 2024 Category: Research Source Type: clinical trials

A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Advanced Bone and Soft Tissue Tumors
Conditions: Osteosarcoma; Sarcoma; Soft Tissue Sarcoma; Bone Tumor Interventions: Drug: Recombinant oncolytic herpes simplex virus type Ⅰ (R130) Sponsors: Shanghai Yunying Medical Technology; Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 14, 2023 Category: Research Source Type: clinical trials

Oncological and Functional Outcomes in Lower Limb Osteosarcoma Pediatric Patient
Conditions: Osteosarcoma; Pediatric; Lower Limb Injury; Outcome Interventions: Other: Retrospective analysis Sponsors: Changye Zou Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 8, 2023 Category: Research Source Type: clinical trials

Cabozantinib With Ifosfamide in Ewing's Sarcoma and Osteosarcoma
Conditions: Ewing Sarcoma; Osteosarcoma Interventions: Drug: Cabozantinib Sponsors: Children ' s Hospital of Philadelphia; Children ' s Hospital Colorado; Exelixis; Alex ' s Lemonade Stand Foundation Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 5, 2023 Category: Research Source Type: clinical trials

Tucidinostat Plus Apatinib for Advanced Osteosarcoma
Conditions: Osteosarcoma Interventions: Drug: Tucidinostat, Apatinib Sponsors: Wuhan Union Hospital, China Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 9, 2023 Category: Research Source Type: clinical trials

Safety and Efficacy of NK510 to Treat Osteosarcoma and Soft Tissue Sarcoma
Conditions: Osteosarcoma; Soft Tissue Sarcoma Interventions: Drug: NK510; Drug: NK510 Sponsors: Base Therapeutics (Shanghai) Co., Ltd.; Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 6, 2023 Category: Research Source Type: clinical trials

Pulmonary Resectable Osteosarcoma Treated by Metastasectomy and Pre-operative Immunotherapy and Stereotactic Body Radiotherapy (PROMIS): a Prospective Clinical Trial
Conditions: Osteosarcoma Interventions: Combination Product: metastasectomy and pre-operative immunotherapy (gemcitabine and penpulimab ) and stereotactic body radiotherapy Sponsors: Ruijin Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 2, 2023 Category: Research Source Type: clinical trials

Liquid Biopsy in Ewing Sarcoma and Osteosarcoma as a Prognostic And Response Diagnostic: LEOPARD
Conditions: Ewing Sarcoma; Ewing Sarcoma of Bone; Ewing Sarcoma of Soft Tissue; Peripheral Primitive Neuroectodermal Tumor; Peripheral Primitive Neuroectodermal Tumor of Bone; Peripheral Primitive Neuroectodermal Tumor of Soft Tissue; High-grade Osteosarcoma Interventions: Other: FoundationOne Liquid CDx Sponsors: Dana-Farber Cancer Institute; Alex ' s Lemonade Stand Foundation; Conquer Cancer Foundation; Harvard University; Sam Day Foundation Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 5, 2023 Category: Research Source Type: clinical trials