No benefit of double dose Tamiflu for severe influenza
People suffering from severe influenza do not benefit from double doses of the antiviral drug oseltamivir (Tamiflu), according to new research. (Source: Nursing Times Breaking News)
Source: Nursing Times Breaking News - May 31, 2013 Category: Nursing Source Type: news

No Benefit Of Double Dose Antiviral Drug For Severe Influenza
Findings have major implications for stockpiling drugs during pandemics, say experts There are no virological or clinical benefits of giving double doses of the antiviral drug oseltamivir (Tamiflu) to patients admitted to hospital with severe influenza, finds a large study from South East Asia published on bmj.com today. This is the first study to examine the effectiveness of higher doses of oseltamivir in cases of hospitalized severe human influenza (seasonal, pandemic and bird flu strains)... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 31, 2013 Category: Consumer Health News Tags: Flu / Cold / SARS Source Type: news

Double dose of Tamiflu proves no better in severe flu
LONDON (Reuters) - There are no benefits from giving patients with severe flu a double dose of Roche's drug Tamiflu, despite calls by some experts for the use of higher doses in the most serious cases. (Source: Reuters: Health)
Source: Reuters: Health - May 31, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

Double Dose of Tamiflu Proves No Better in Severe Flu
There are no benefits from giving patients with severe flu a double dose of Roche's drug Tamiflu, despite calls by some experts for the use of higher doses in the most serious cases.Source: Reuters Health Related MedlinePlus Pages: Flu, International Health (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - May 30, 2013 Category: Consumer Health News Source Type: news

Double Dose of Tamiflu Proves No Better in Severe Flu
There are no benefits from giving patients with severe flu a double dose of Roche's drug Tamiflu, despite calls by some experts for the use of higher doses in the most serious cases. (Source: RWJF News Digest - Public Health)
Source: RWJF News Digest - Public Health - May 30, 2013 Category: American Health Source Type: news

Double dose of antiviral drug offers no added benefit in severe influenza
(Wellcome Trust) Giving double doses of the antiviral drug oseltamivir, or Tamiflu, offers no clinical or virological advantages over a standard dose for patients admitted to hospital with severe influenza infection, according to a randomized trial published today and funded by the Wellcome Trust, US National Institute of Allergy and Infectious Diseases and the Singapore National Medical Research Council. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - May 30, 2013 Category: Infectious Diseases Source Type: news

Drug Resistance To Tamiflu Confirmed For H7N9 Virus
Resistance to treatment with Tamiflu (oseltamivir) and similar drugs in people who have the H7N9 flu virus has now been confirmed, according to new research published in The Lancet. Described as one of the most detailed virological studies of the H7N9 virus to date, the study was led by Dr Zhenghong Yuang of the Shanghai Public Health Clinical Centre and School of Basic Medical Sciences, Shanghai Medical College of Fudan University, China, and Dr Malik Peiris, of the University of Hong Kong, China... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 29, 2013 Category: Consumer Health News Tags: Flu / Cold / SARS Source Type: news

New China Bird Flu May Be Resistant to Tamiflu
Title: New China Bird Flu May Be Resistant to TamifluCategory: Health NewsCreated: 5/28/2013 12:36:00 PMLast Editorial Review: 5/29/2013 12:00:00 AM (Source: MedicineNet Hepatitis C General)
Source: MedicineNet Hepatitis C General - May 29, 2013 Category: Infectious Diseases Source Type: news

Clinical confirmation of H7N9 virus resistance to Tamiflu
Genetic testing confirms antiviral resistanceRelated items from OnMedicaScientists confirm transmission of influenza A H7N9 from birds to peopleResistance to Tamiflu - 'to be expected' says RocheQuestions remain about effectiveness of Tamiflu, experts warnDrug giant agrees to release all Tamiflu trial dataTamiflu cut illness in swine flu (Source: OnMedica Latest News)
Source: OnMedica Latest News - May 29, 2013 Category: UK Health Source Type: news

Bird-Flu Virus Shows Tamiflu Resistance
The bird-flu strain H7N9 virus that has killed 36 people since the beginning of the year has shown resistance to flu vaccine Tamiflu in a small-scale trial in China, according to research published Tuesday in the Lancet medical journal. (Source: WSJ.com: Health)
Source: WSJ.com: Health - May 29, 2013 Category: Pharmaceuticals Tags: PAID Source Type: news

Drug-resistant strains of H7N9 bird flu discovered
Researchers confirmed three patients had viral strains of H7N9 that could not be treated by Tamiflu and other current therapies (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - May 29, 2013 Category: Consumer Health News Source Type: news

Tamiflu Resistance Found in Some Cases of New Bird FluTamiflu Resistance Found in Some Cases of New Bird Flu
Scientists have established for the first time that a new strain of bird flu which has killed 36 people in China is, in some cases, resistant to pharmaceutical company Roche's widely-used flu drug Tamiflu. Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 28, 2013 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Tamiflu Resistance Confirmed in H7N9 Flu Cases (CME/CE)
(MedPage Today) -- Chinese researchers reported, for the first time, clinical evidence of oseltamivir (Tamiflu) resistance in patients infected with the novel avian H7N9 flu. (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - May 28, 2013 Category: Infectious Diseases Source Type: news

Two die after h7n9 bird flu virus develops drug resistance
The Lancet reports that H7N9 is already showing the ability to mutate to avoid treatment with TamifluScientists have found the first cases of the new bird flu virus proving resistant to treatment with Tamiflu or similar drugs. The virus has so far killed 36 people in China and been confirmed in 95 others.The analysis of the course of the H7N9 bird flu virus and use of antivirals in 14 patients, reported in the Lancet medical journal, found that three severely ill people did not respond to the group of medicines that are the standard weapon against threatened flu pandemics. Two died and the third still needed specialis...
Source: Guardian Unlimited Science - May 28, 2013 Category: Science Authors: James Meikle Tags: Bird flu Asia Pacific World news Health guardian.co.uk Society China Science Source Type: news

Drug resistance in new China bird flu raises concern
LONDON (Reuters) - The new bird flu strain that has killed 36 people in China has proved resistant to Tamiflu for the first time, a development scientists said was "concerning". (Source: Reuters: Health)
Source: Reuters: Health - May 28, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

Drug Resistance in New China Bird Flu Raises Concern
The new bird flu strain that has killed 36 people in China has proved resistant to Tamiflu for the first time, a development scientists said was "concerning". Source: Reuters Health Related MedlinePlus Pages: Antibiotics, Bird Flu (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - May 28, 2013 Category: Consumer Health News Source Type: news

Tamiflu resistance found in some cases of new bird flu
LONDON (Reuters) - Scientists have established for the first time that a new strain of bird flu which has killed 36 people in China is, in some cases, resistant to pharmaceutical company Roche's widely-used flu drug Tamiflu. (Source: Reuters: Health)
Source: Reuters: Health - May 28, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

£74m of Tamiflu thrown away by NHS
Supplies of anti-flu drug had to be thrown away because "shocking incompetence" meant it was unclear if it had been kept refrigerated.     (Source: Telegraph Health)
Source: Telegraph Health - May 21, 2013 Category: Consumer Health News Source Type: news

100 Top-Selling Drugs Report Released 100 Top-Selling Drugs Report Released
Acid blocker esomeprazole and antipsychotic drug aripiprazole remain the top-selling US prescription drugs. Sales climbed for oseltamivir because of a severe influenza season, according to Drugs.com. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 10, 2013 Category: Consumer Health News Tags: Family Medicine/Primary Care News Source Type: news

April's top stories: Roche discloses Tamiflu data, Novartis patent rejected in India
Roche finally reveals its full Tamiflu data to researchers after a three year delay, Norvartis loses cancer patent bid in landmark ruling in India, and $100m brain research project launched in US. Pharmaceutical-technology.com wraps up the key headli… (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - May 1, 2013 Category: Pharmaceuticals Source Type: news

Sewage Study Reveals Half Of Tamiflu Prescriptions Went Unused During 2009 H1N1 Swine Flu Pandemic
A new study concludes that approximately half of the prescriptions of Tamiflu during the 2009-10 influenza pandemic went unused in England. The unused medication represents approximately 600,000 courses of Tamiflu at a cost of around 7.8 million pounds to the UK taxpayer. The novel scientific method used in the study could help measure and improve the effectiveness of future pandemic flu strategies... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 20, 2013 Category: Consumer Health News Tags: Flu / Cold / SARS Source Type: news

Half of Tamiflu prescriptions went unused during 2009 H1N1 swine flu pandemic, UK sewage study
(Centre for Ecology & Hydrology) A new study concludes that approximately half of the prescriptions of Tamiflu during the 2009-10 influenza pandemic went unused in England. The unused medication represents approximately 600,000 courses of Tamiflu at a cost of around £7.8 million to the UK taxpayer. The finding, published online in the open access scientific journal PLOS ONE, comes from the first study of its kind to use sewage water to estimate drug compliance rates. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 17, 2013 Category: Global & Universal Source Type: news

Cancer Drugs, Tamiflu Aid Roche
Swiss drug maker Roche reported a 5% increase in first-quarter sales that was boosted by strong performances by its cancer drugs in the U.S. and emerging markets as well as demand for its Tamiflu influenza treatment. (Source: WSJ.com: Health)
Source: WSJ.com: Health - April 11, 2013 Category: Pharmaceuticals Tags: PAID Source Type: news

Tamiflu and cancer drugs lift Roche above forecasts
LONDON (Reuters) - A spike in U.S. demand for flu drug Tamiflu and strong sales of mainstay cancer medicines lifted first-quarter sales at Roche Holding AG by a bigger-than-expected 5 percent. (Source: Reuters: Health)
Source: Reuters: Health - April 11, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

Roche Group posts strong sales growth in the first quarter
Group sales increase 6% at CER to 11.6 billion Swiss francs; Pharmaceuticals sales rise 7% to 9.2 billion Swiss francs, driven by cancer medicines and Tamiflu; Successful launches of Kadcyla and Perjeta strengthen HER2-positive breast cancer franchise (Source: Roche Media News)
Source: Roche Media News - April 11, 2013 Category: Pharmaceuticals Source Type: news

Roche Group posts strong sales growth in the first quarter
Group sales increase 6% at CER to 11.6 billion Swiss francs; Pharmaceuticals sales rise 7% to 9.2 billion Swiss francs, driven by cancer medicines and Tamiflu; Successful launches of Kadcyla and Perjeta strengthen HER2-positive breast cancer franchise; Diagnostics sales rise 1% to 2.4 billion Swiss francs; strong growth in Professional Diagnostics (+5%), decline in Diabetes Care (-5%); Full-year outlook confirmed (Source: Roche Investor Update)
Source: Roche Investor Update - April 11, 2013 Category: Pharmaceuticals Source Type: news

Roche Agree To Release All Trial Data On Tamiflu Drug
The BMJ can reveal that following over three years of talks with pharmaceutical giant Roche, the Cochrane Collaboration is at last being granted access to "all 74 Roche-sponsored trials" of the influenza drug, Tamiflu (oseltamivir). In an email to the Cochrane researchers on 2 April, Roche said they would provide "each CSR [clinical study report]" over the next few months. The reports will be edited by Roche "to ensure patient confidentiality and to protect legitimate commercial interests"... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 6, 2013 Category: Consumer Health News Tags: Flu / Cold / SARS Source Type: news

Roche Agrees to Release Tamiflu Data
Bowing to years of pressure, Swiss drug maker Roche said it would release clinical trial data for its blockbuster Tamiflu influenza treatment to scientists who question the drug's efficacy. (Source: WSJ.com: Health)
Source: WSJ.com: Health - April 6, 2013 Category: Pharmaceuticals Tags: PAID Source Type: news

After long fight, Roche to release all Tamiflu drug data
LONDON (Reuters) - After a lengthy fight, Swiss drugmaker Roche Holding AG said it had agreed to hand over data from all clinical trials of its best-selling flu drug Tamiflu to a group of outside researchers. (Source: Reuters: Health)
Source: Reuters: Health - April 4, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

Roche to release all Tamiflu data
The drug company Roche has announced that it will give researchers access to all its trial data for the influenza drug Tamiflu, the BMJ reports. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - April 4, 2013 Category: Consumer Health News Source Type: news

Roche releases all trial data on Tamiflu drug
The BMJ can reveal that following over three years of talks with pharmaceutical giant Roche, the Cochrane Collaboration is at last being granted access to “all 74 Roche-sponsored trials” of the influenza drug, Tamiflu (oseltamivir). (Source: Pharmacy Europe)
Source: Pharmacy Europe - April 4, 2013 Category: Drugs & Pharmacology Source Type: news

After Fight, Roche to Release All Tamiflu Drug DataAfter Fight, Roche to Release All Tamiflu Drug Data
After a lengthy fight, Swiss drug maker Roche Holding AG said it had agreed to hand over data from all clinical trials of its best-selling flu drug Tamiflu to a group of outside researchers. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 4, 2013 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Tamiflu Resistant Swine Flu Virus Circulating In The Population
Tamiflu-resistant strains of H1N1pdm09 (2009 pandemic Swine Flu) are being increasingly detected in community patients who never received the drug, suggesting that the resistant strains are spreading, a researcher from the World Health Organization (WHO) in Melbourne Australia, announced at the Annual Scientific Meeting of the Australasian Society for Infectious Diseases (ASID) in Canberra, Australia. Dr... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 19, 2013 Category: Consumer Health News Tags: Flu / Cold / SARS Source Type: news

Swine flu 'growing in resistance' to Tamiflu
Strains of swine flu that are resistant to the drug Tamiflu are spreading, say experts, raising more questions about a government decision to spend £500 million stockpiling it. (Source: Telegraph Health)
Source: Telegraph Health - March 18, 2013 Category: Consumer Health News Tags: h1n1 roche tamiflu resistance swine flu Source Type: news

Roche chief executive dismisses Tamiflu trials doubts
The chief executive of the drugs giant that makes Tamiflu, which some claim could be no more effective than paracetamol, has dismissed concerns from scientists pressing it to release all trials results on the remedy. (Source: Telegraph Health)
Source: Telegraph Health - March 1, 2013 Category: Consumer Health News Tags: roche all trials tamiflu Source Type: news

NHS Choices 'Behind the Headlines' assessment of press reports that a "new antiviral may help in flu fight"
Source: NHS Choices Area: News The 'Behind the Headlines' service from NHS Choices has featured a quality assessment of press reports that a 'flu drug shows promise in overcoming resistance' (BBC news and other; 22nd Feb 2013).   The reports are based on early stage laboratory and animal research, which examined the effectiveness of a possible new antiviral treatment for flu. It was found in the laboratory to be similarly or more effective than zanamivir at stopping the influenza virus from spreading between cells, including strains with demonstrated resistance to oseltamivir and zanamivir. The chemical was also ...
Source: NeLM - News - February 25, 2013 Category: Drugs & Pharmacology Source Type: news

New antiviral may help in flu fight
Conclusion There are currently only two flu drugs authorised for use in the UK. As they become more widely used, flu viruses will inevitably develop resistance to them. This is particularly likely to be a problem for the more widely used Tamiflu. Research exploring new flu drugs that act in different ways could be very useful as flu can be a deadly disease, particularly in vulnerable population groups. This new research demonstrates that a new chemical has the potential to be developed into a flu drug as it was found to be similarly or more effective than Relenza at stopping the spread of the flu virus in the laboratory, i...
Source: NHS News Feed - February 22, 2013 Category: Consumer Health News Tags: Medical practice Medication Source Type: news

Children's Tamiflu Still in Short Supply
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - February 22, 2013 Category: Journals (General) Source Type: news

Kids' Tamiflu Still in Short Supply
With flu season dragging on, supplies of the children’s version of flu drug Tamiflu continue to dwindle nationwide, according to the drug's maker. (Source: WebMD Health)
Source: WebMD Health - February 21, 2013 Category: Consumer Health News Source Type: news

Infant outcomes among pregnant women who used oseltamivir for treatment of influenza during the H1N1 epidemic
Source: American Journal of Obstetrics and Gynecology Area: News According to research reported early online in the American Journal of Obstetrics and Gynecology, use of oseltamivir to treat or prevent H1N1 influenza during pregnancy does not appear to increase the risk of early birth, poor foetal growth or a low Apgar score at birth.   The researchers note that only a few studies have examined the association between maternal use of oseltamivir and pregnancy outcomes. Although the benefit of treatment of pregnant women with antivirals is presumed to outweigh its risks, the limited information available is challe...
Source: NeLM - News - February 4, 2013 Category: Drugs & Pharmacology Source Type: news

Tamiflu's Usefulness Remains Under Question
(Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - January 28, 2013 Category: Primary Care Tags: Medical News Source Type: news

Flu Deaths ‘Unpredictable’
WebMD Medical News By Daniel J. DeNoon Reviewed by Laura J. Martin, MD Aug. 26, 2010 – U.S. deaths from flu range from about 3,000 to about 50,000 per year, the CDC now calculates. The new numbers come from analysis of the last 31 flu seasons by CDC medical officer David Shay, MD, MPH and colleagues. For years, the CDC has been estimating the annual flu toll at about 36,000 flu-related deaths per year. But that average came from the years 1990-1999. The H3N2 type A flu bug dominated eight of those nine flu seasons — and the Shay study finds that H3N2 seasons are nearly three times as deadly as H1N1 type A or t...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 23, 2013 Category: Consumer Health News Authors: mreal197 Tags: WebMD News Source Type: news

FDA: Spot shortages for flu drug Tamiflu
WASHINGTON, Jan. 19 (UPI) -- The elderly, pregnant, and those with asthma, diabetes or heart disease with the flu should get antivirals, but there are some shortages, a U.S. official says. (Source: Health News - UPI.com)
Source: Health News - UPI.com - January 19, 2013 Category: Consumer Health News Source Type: news

CDC Urges Tamiflu Rx to Curb Flu Death RateCDC Urges Tamiflu Rx to Curb Flu Death Rate
CDC Director Thomas Frieden said clinicians are not prescribing the antiviral as readily as they did in the pandemic season of 2009-2010. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 19, 2013 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Flu Stretches Hospitals, Drug Supplies Nationwide
WebMD Medical News By Brenda Goodman, MA Reviewed by Laura J. Martin, MD Jan. 10, 2013 — The early flu season has turned severe in some parts of the country, stretching health care providers and drug supplies. According to the latest numbers from the CDC, there’s now widespread flu activity in 41 states. New York City and 29 states are reporting a high number of cases of flu-like illness. So far this flu season, 2,257 people have been hospitalized with laboratory-confirmed flu. Eighteen children have died. The number of deaths attributed to both pneumonia and the flu is still below epidemic levels. How much wo...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 17, 2013 Category: Consumer Health News Authors: mreal197 Tags: WebMD News Source Type: news

Coughs Can Last About Two Weeks
WebMD Medical News By Denise Mann Reviewed by Laura J. Martin, MD Jan.  14, 2013 — Just how long should that pesky cough last? The answer, according to most doctors, is close to 18 days. Yet many people with a cough get antsy after about five to nine days, a new study shows. “Coughs last for longer than we think they do,” says researcher Mark H. Ebell, MD, a family doctor at the University of Georgia in Athens. “People think it should be over in a little over a week, but the reality is that a cough is more likely to last two weeks.” In the study, researchers asked 500 adults from Georgia...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 17, 2013 Category: Consumer Health News Authors: mreal197 Tags: WebMD News Source Type: news

'Spot' Shortages of Flu Vaccine, Tamiflu Reported, FDA Head Says
Agency is offering tips on how to find the shot or medication at a clinic or pharmacy near you Source: HealthDay Related MedlinePlus Pages: Flu, Immunization (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - January 15, 2013 Category: Consumer Health News Source Type: news

U.S. faces shortages of flu vaccine, Tamiflu treatment
(Reuters) - One of the worst U.S. flu seasons in a decade has created shortages of vaccine and the Tamiflu treatment for children, raising the prospect that people considered at high risk of getting the flu might not get the protection they need. (Source: Reuters: Health)
Source: Reuters: Health - January 11, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

Children’s Flu Medicine in Short Supply
Pharmacies face shortages of liquid Tamiflu because its supplier cannot keep up with demand, officials say. (Source: NYT Health)
Source: NYT Health - January 10, 2013 Category: Consumer Health News Authors: By ANAHAD O’CONNOR Tags: Drugs (Pharmaceuticals) Genentech Inc Influenza CVS Caremark Corporation CVS NYSE Tamiflu (Drug) Source Type: news

FDA Current Drug Shortages: Oseltamivir Phosphate (Tamiflu) for Oral Suspension (6mg/mL 60 mL)
(Initial Posting Date) – 1/10/2013 (Source: CDC Flu updates)
Source: CDC Flu updates - January 10, 2013 Category: Infectious Diseases Source Type: news