European Panel Endorses Generic Version of OseltamivirEuropean Panel Endorses Generic Version of Oseltamivir
Ebilfumin was shown to be bioequivalent to the brand-name product Tamiflu. International Approvals (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 21, 2014 Category: Consumer Health News Tags: Infectious Diseases News Alert Source Type: news

Tamiflu® reduces risk of death by 25% in adults hospitalised with H1N1 pandemic influenza
Adults hospitalised with H1N1 influenza during the 2009-2010 pandemic were 25% less likely to die from the disease if they were given antiviral drugs called neuraminidase inhibitors (NAIs) such as Tamiflu®, according to a large meta-analysis involving more than 29 000 patients from 38 countries, published in The Lancet Respiratory Medicine journal. The findings also indicate that treatment within 2 days of flu symptoms developing halved the risk of death compared with later treatment or no treatment."Many governments have stockpiles of Tamiflu that are close to expiry. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 19, 2014 Category: Consumer Health News Tags: Flu / Cold / SARS Source Type: news

Roche-backed study finds Tamiflu saved lives in flu pandemic
LONDON (Reuters) - Using Roche's medicine Tamiflu saved lives during the H1N1 swine flu pandemic four years ago, according to a new scientific study published on Wednesday. (Source: Reuters: Health)
Source: Reuters: Health - March 19, 2014 Category: Consumer Health News Tags: healthNews Source Type: news

Tamiflu reduced risk of death in H1N1 influenza pandemic
Hospitalised patients who took Tamiflu were 25 % less likely to dieRelated items from OnMedicaSpending watchdog criticises government over TamifluDrug giant agrees to release all Tamiflu trial dataSwine flu jab very effectiveSwine flu deaths cut by blood oxygenationPandemic flu death toll could be 15 times higher (Source: OnMedica Latest News)
Source: OnMedica Latest News - March 19, 2014 Category: UK Health Source Type: news

Tamiflu Saved Lives During Swine Flu Pandemic, Study Confirms
Best to start treatment within 48 hours, experts saySource: HealthDay Related MedlinePlus Pages: H1N1 Flu (Swine Flu), Medicines (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - March 19, 2014 Category: Consumer Health News Source Type: news

Natco Pharma gets USFDA tentative nod for generic Tamiflu
The tentative approval of Oseltamivir Phosphate capsules by the US Food and Drug Administration is for multiple strengths of 30mg, 45 mg and 75 mg. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - March 18, 2014 Category: Pharmaceuticals Source Type: news

Statins have no side effects? This is what our study really found … | Ben Goldacre
This article first appeared on Ben Goldacre's own website, Bad ScienceDrugsPlacebo effectMedical researchHealthBen Goldacretheguardian.com © 2014 Guardian News and Media Limited or its affiliated companies. All rights reserved. | Use of this content is subject to our Terms & Conditions | More Feeds (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - March 14, 2014 Category: Science Authors: Ben Goldacre Tags: theguardian.com Blogposts Placebo effect Health Medical research Society Drugs Science Source Type: news

Genentech Resolves Tamiflu Shortage
Roche/Genentech announced that the shortage of the liquid form of Tamiflu in the US has been resolved. The shortage occurred during the flu season, but lasted less than two weeks. The FDA has already taken the product off its drug shortage list. (Source: Pharmaceutical Online News)
Source: Pharmaceutical Online News - January 21, 2014 Category: Pharmaceuticals Source Type: news

H1N1 Tamiflu Resistance Spreading In Mississippi
The commentary discusses the spread of H274Y H1N1 Tamiflu resistance in Mississippi. (01/17/14 16:00) (Source: Recombinomics)
Source: Recombinomics - January 17, 2014 Category: Infectious Diseases Source Type: news

UPDATED: FDA Current Drug Shortages: Oseltamivir Phosphate (Tamiflu) for Oral Suspension (6mg/mL 60 mL)
(Source: CDC Flu updates)
Source: CDC Flu updates - January 16, 2014 Category: Infectious Diseases Source Type: news

FDA Announces Shortage of Children's Tamiflu
The commentary discusses the FDA’s announcement of a children’s Tamiflu shortage (01/07/14 21:00) (Source: Recombinomics)
Source: Recombinomics - January 11, 2014 Category: Infectious Diseases Source Type: news

Tamiflu Resistance Driving Severe pH1N1 Cases In California?
The commentary discusses the possible role of Tamiflu resistance in severe pH1N1 cases in northern California. (01/05/14 08:00) (Source: Recombinomics)
Source: Recombinomics - January 11, 2014 Category: Infectious Diseases Source Type: news

Tamiflu Shortage Again
WebMD Health News By Rita Rubin Reviewed by Arefa Cassoobhoy, MD, MPH Jan. 8, 2014 — The liquid form of the flu drug Tamiflu is in short supply because of early strong demand. But the shortage is expected to be brief, lasting only through mid-January, according to its manufacturer, Genentech. Doctors typically give the liquid form of the antiviral drug, called Tamiflu OS, to children under age 13 or to people who have trouble swallowing. It is approved for babies as young as 2 weeks old. “There has been strong and early demand for Tamiflu Oral Suspension (OS), and we are experiencing a temporary delay in packag...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 9, 2014 Category: Consumer Health News Authors: mreal197 Tags: WebMD News Source Type: news

Tamiflu Shortage Again
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - January 9, 2014 Category: Journals (General) Source Type: news

Tamiflu Oral Suspension in Short Supply (FREE)
By the Editors The FDA is reporting a temporary shortage of the antiviral Tamiflu's oral … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - January 9, 2014 Category: Primary Care Source Type: news

Liquid Tamiflu Shortage in USLiquid Tamiflu Shortage in US
The liquid formulation of the antiviral drug oseltamivir is in short supply because of early strong demand, according to its manufacturer. WebMD Health News (Source: Medscape Pediatrics Headlines)
Source: Medscape Pediatrics Headlines - January 9, 2014 Category: Pediatrics Tags: Infectious Diseases News Source Type: news

UPDATED: FDA Current Drug Shortages: Oseltamivir Phosphate (Tamiflu) for Oral Suspension (6mg/mL 60 mL)
(Source: CDC Flu updates)
Source: CDC Flu updates - January 7, 2014 Category: Infectious Diseases Source Type: news

Responses to the Public Accounts Committee report: "Access to clinical trial information and the stockpiling of Tamiflu"
The Public Accounts Committee has today called on the Government to ensure that full methods and results from clinical trials of all treatments currently used in the UK are available to doctors and researchers. This echoes the call of the AllTrials campaigni for all clinical trials to be registered and results reported. The AllTrials petition calling on governments, regulators and research bodies to implement measures to achieve this has been signed by over 60,000 people. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 3, 2014 Category: Consumer Health News Tags: Clinical Trials / Drug Trials Source Type: news

Drug companies 'witholding research' from doctors MPs warn
A powerful committee of MPs says firms should release all trial results for new and existing drugs     (Source: Telegraph Health)
Source: Telegraph Health - January 3, 2014 Category: Consumer Health News Tags: PAC clinical trials richard bacon research flu tamiflu public accounts drug companies Source Type: news

Drug companies 'withholding research' from doctors, MPs warn
A powerful committee of MPs says firms should release all trial results for new and existing drugs     (Source: Telegraph Health)
Source: Telegraph Health - January 3, 2014 Category: Consumer Health News Tags: PAC clinical trials richard bacon research flu tamiflu public accounts drug companies Source Type: news

Drug companies 'witholding research' from doctors, MPs warn
A powerful committee of MPs says firms should release all trial results for new and existing drugs     (Source: Telegraph Health)
Source: Telegraph Health - January 3, 2014 Category: Consumer Health News Tags: PAC clinical trials richard bacon research flu tamiflu public accounts drug companies Source Type: news

UK lawmakers criticize govt's stockpiling of Roche drug Tamiflu
LONDON (Reuters) - British lawmakers on Friday criticized government spending of 424 million pounds ($702 million) to stockpile Roche's medicine Tamiflu, saying doubts about the drug's effectiveness suggest it may not be money well spent. (Source: Reuters: Health)
Source: Reuters: Health - January 3, 2014 Category: Consumer Health News Tags: healthNews Source Type: news

Drug firms accused of holding back complete information on clinical trials
MPs voice concern after report into decision to stockpile Tamiflu finds discussions about effectiveness hampered by practice Clinical trial results are being routinely withheld from doctors, undermining their ability to make informed decisions about how to treat patients, an influential parliamentary committee has claimed.MPs have expressed "extreme concern" that drug manufacturers appear to only publish around 50% of completed trial results and warned that the practice has "ramifications for the whole of medicine".Their conclusions have emerged in a public accounts committee report which examined the D...
Source: Guardian Unlimited Science - January 3, 2014 Category: Science Authors: Rajeev Syal Tags: The Guardian Pharmaceuticals industry News Drugs UK news Business Science Source Type: news

H1N1 Tamiflu Resistance Spread In Sapporo Japan
The commentary discusses the clonal expansion of H1N1 H274Y in Sapporo, Japan. (12/29/13 23:45) (Source: Recombinomics)
Source: Recombinomics - December 30, 2013 Category: Infectious Diseases Source Type: news

H1N1 Swine Flu Tamiflu Resistance Spreads To Mississippi
The commentary discusses the spread of H1N1 Tamiflu resistance H274Y from Louisiana to Mississippi. (12/23/13 13:15) (Source: Recombinomics)
Source: Recombinomics - December 23, 2013 Category: Infectious Diseases Source Type: news

H1N1pdm09 Louisiana Tamiflu Resistance Cluster Expands
The commentary discusses the clonal expansion of H274Y in Louisiana. (12/18/13 02:00) (Source: Recombinomics)
Source: Recombinomics - December 19, 2013 Category: Infectious Diseases Source Type: news

Preparing against Tamiflu-resistant influenza viruses
Researchers in Umea and Uppsala have found that residues of the influenza drug Tamiflu in our environment can make the influenza virus in birds resistant. This can have serious consequences in the event of an influenza pandemic. With more than 14 million SEK from the Swedish Research Councils Formas and VR, the research team will now continue their studies with a focus on alternative antiviral drugs.Influenza is a viral respiratory infection that spreads rapidly and cause widespread epidemics. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 11, 2013 Category: Consumer Health News Tags: Bird Flu / Avian Flu Source Type: news

New bird flu H7N9 resists first-line treatments like Tamiflu
Unlike seasonal flu strains, new H7N9 bird flu does not lose any of its spreading potential with drug resistance (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - December 10, 2013 Category: Consumer Health News Source Type: news

Better preparedness against Tamiflu-resistant influenza viruses
(Umea University) Swedish researchers in Umeå and Uppsala have found that residues of the influenza drug Tamiflu in our environment can make the influenza virus in birds resistant. This can have serious consequences in the event of an influenza pandemic. With more than 14 million SEK from the Swedish Research Councils Formas and VR, the research team will now continue their studies with a focus on alternative antiviral drugs. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 9, 2013 Category: Global & Universal Source Type: news

Louisiana H1N1 Tamiflu Resistance Expands to Utah
The commentary discusses the spread of the Tamiflu resistant H1N1pdm09 sequences in Louisiana to Utah. (12/03/13 23:45) (Source: Recombinomics)
Source: Recombinomics - December 4, 2013 Category: Infectious Diseases Source Type: news

H1N1pdm09 Louisiana Tamiflu Resistant Cluster Grows
The commentary discusses the third Tamiflu resistant H1N1pdm09 case in Louisiana. (12/03/13 20:30) (Source: Recombinomics)
Source: Recombinomics - December 4, 2013 Category: Infectious Diseases Source Type: news

CDC Investigates H1N1pdm09 H274Y Cluster
The commentary discusses the CDC investigation of H274Y Tamiflu resistance in Louisiana. (11/25/13 19:30) (Source: Recombinomics)
Source: Recombinomics - November 27, 2013 Category: Infectious Diseases Source Type: news

Kids Hospitalized for Flu Need Antiviral Meds Right Away: Study
Survival odds increase with early administration of drugs such as oseltamivir, researchers say (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - November 27, 2013 Category: Respiratory Medicine Authors: webmaster at doctorslounge.com Tags: Infections, Nursing, Pediatrics, Pharmacy, Pulmonology, News, Source Type: news

Well: Lifesaving Flu Drugs Fall in Use in Children
Prompt use of antiviral medications can save the lives of flu-stricken children — yet the drugs are being used less frequently than they once were, a study finds.     (Source: NYT)
Source: NYT - November 25, 2013 Category: American Health Authors: By CATHERINE SAINT LOUIS Tags: Family Babies and Infants Influenza Preventive Medicine Body Relenza (Drug) Parenting Featured Children and Childhood Tamiflu (Drug) Source Type: news

Kids Hospitalized for Flu Need Antiviral Meds Right Away: Study
Survival odds increase with early administration of drugs such as oseltamivir, researchers say (Source: WebMD Health)
Source: WebMD Health - November 25, 2013 Category: Consumer Health News Source Type: news

Kids Hospitalized for Flu Need Antiviral Meds Right Away
Survival odds increase with early administration of drugs such as oseltamivir, researchers saySource: HealthDay Related MedlinePlus Pages: Children's Health, Flu, Medicines (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - November 25, 2013 Category: Consumer Health News Source Type: news

US H1N1pdm09 Tamiflu Resistance Increases
The commentary discusses the increase in H274Y Tamiflu resistance in the week 46 FluView. (11/22/13 18:30) (Source: Recombinomics)
Source: Recombinomics - November 23, 2013 Category: Infectious Diseases Source Type: news

H1N1pdm09 Louisiana Tamiflu Resistance Cluster
The commentary discusses the H1N1pdm09 Tamiflu resistance (H274Y oseltamivir) in Louisiana. (11/19/13 21:45) (Source: Recombinomics)
Source: Recombinomics - November 23, 2013 Category: Infectious Diseases Source Type: news

Taiwan: first human case of new bird flu virus
The world's first case of a wild avian influenza A H6N1 virus has been confirmed in a 20-year-old Taiwanese woman. Scientists who analyzed the virus found it has a genetic mutation, allowing it to get into human cells and cause infection.Results of their findings were published in a study in The Lancet Respiratory Medicine.The woman entered a hospital in central Taiwan in May 2013 with flu-like symptoms and difficulty breathing. Her doctors say she fully recovered after treatment with oseltamivir (Tamiflu). (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 14, 2013 Category: Consumer Health News Tags: Flu / Cold / SARS Source Type: news

Experts with links to drugs industry 'hyped swine flu'
Conclusion This was a well-conducted study, albeit based on a small sample of articles. The finding that academics with ties to the drugs industry were more likely to make a higher assessment of risk from swine flu, and those promoting the use of antiviral drugs were more likely to have industry links, is worrying. The general issue of academics with undisclosed links to the pharmaceutical industry being interviewed by journalists is of concern. That said, the study does not prove that media coverage either fuelled public anxiety about swine flu or the policy decisions made about drug or vaccine funding. Si...
Source: NHS News Feed - November 12, 2013 Category: Consumer Health News Tags: Medical practice Medication Swine flu Source Type: news

MPs call for more transparent clinical trials
"Drug companies and medical researchers are putting patients' lives in danger by failing to publish unfavourable results from clinical trials, MPs have warned," The Guardian reports. The news follows the recent publication of a report (PDF, 2.3Mb) by the influential House of Commons Science and Technology Committee, which called for greater transparency in clinical trials and the data they produce.   What are clinical trials? There is currently no regulatory definition of exactly what constitutes a clinical trial. The term is generally understood to mean a study that assesses how effective an...
Source: NHS News Feed - September 18, 2013 Category: Consumer Health News Tags: Medication QA articles Source Type: news

Triple-Dose Flu Remedy Hastens H1N1 Viral ClearanceTriple-Dose Flu Remedy Hastens H1N1 Viral Clearance
High-dose oseltamivir helps eradicate H1N1 influenza faster than the standard regimen, a new study suggests. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 17, 2013 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Triple Dose Tamiflu Beats Back H1N1 (CME/CE)
DENVER (MedPage Today) -- Patients critically ill with H1N1 influenza who received a triple dose of oseltamivir had a significantly more rapid viral clearance than those who received normal doses, researchers reported here. (Source: MedPage Today Emergency Medicine)
Source: MedPage Today Emergency Medicine - September 13, 2013 Category: Emergency Medicine Source Type: news

Breaking the Seal on Drug Research
More researchers are insisting on seeing all the data behind all clinical trials for drugs, not just the rosy reports that companies choose to release.     (Source: NYT Health)
Source: NYT Health - June 30, 2013 Category: Consumer Health News Authors: By KATIE THOMAS Tags: Clinical Trials Drugs (Pharmaceuticals) Roche Holding A G RHHBY Other OTC Sanofi SA SNY NYSE Research Doshi, Peter Cochrane Collaboration Medtronic Inc MDT NYSE GlaxoSmithKline PLC GSK NYSE Tamiflu (Drug) Source Type: news

Dueling Reviews for Controversial Flu Drug
A debate is raging over how well the blockbuster drug Tamiflu would work in an influenza pandemic, and another team is gearing up for yet another analysis. (Source: ScienceNOW)
Source: ScienceNOW - June 28, 2013 Category: Science Source Type: news

Emergence of H7N9 R292K Tamiflu Resistance
The commentary discusses emergence of H7N9 R292K Tamiflu (oseltamivir) resistance. (05/28/13 18:30) (Source: Recombinomics)
Source: Recombinomics - June 7, 2013 Category: Infectious Diseases Source Type: news

High Doses of Tamiflu No Help in Severe Flu (CME/CE)
(MedPage Today) -- Treating severe cases of influenza with double doses of oseltamivir (Tamiflu) was no more effective than giving standard doses, a randomized multicenter trial showed. (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - June 4, 2013 Category: Pediatrics Source Type: news

Double antiviral dose 'no benefit' in severe influenza
Research findings are welcome news for clinical management and pandemic preparednessRelated items from OnMedicaSpending watchdog criticises government over TamifluResistance to Tamiflu - 'to be expected' says RocheEvidence on Tamiflu remains unclear say expertsDrug giant agrees to release all Tamiflu trial dataClinical confirmation of H7N9 virus resistance to Tamiflu (Source: OnMedica Latest News)
Source: OnMedica Latest News - June 3, 2013 Category: UK Health Source Type: news

Doubled Oseltamivir Dose No More Effective Against InfluenzaDoubled Oseltamivir Dose No More Effective Against Influenza
Doubling the dose of oseltamivir does not improve outcomes in patients with severe influenza, according to randomized trial results; the finding could help preserve stockpiles in a future pandemic. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 1, 2013 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news