Gait Disturbance … of Red Herrings, Oranges, and Lemons - A Case of Missed Vitamin C Deficiency and Lessons Learnt
Acta Medica (Hradec Kralove). 2023;66(3):122-127. doi: 10.14712/18059694.2024.5.ABSTRACTVitamin C deficiency resulting in scurvy, is considered to be a rare nutritional disorder in developed countries, thus leading to underdiagnosis with exposure to unnecessary investigations and delay in appropriate treatment. The wide myriad of clinical signs and symptoms with which vitamin C deficiency can present (including haematological, musculoskeletal and vague constitutional symptoms that overlap with other common medical conditions), also contributes to this diagnostic challenge. Despite scurvy being habitually thought to be pres...
Source: Acta Medica: Hradec Kralove - March 21, 2024 Category: General Medicine Authors: Nadine Anne De Battista Marie Claire Zammit Sandro Galea Soler Stephen Attard Source Type: research

Investigating the effect of hesperetin on estrogen receptor alpha (ER α) expression, phosphorylation and activity in MCF-7 cells
CONCLUSION: Based on the results of this study, it can be concluded that hesperetin has a significant effect on ERα expression, phosphorylation and activity.PMID:38462023 | DOI:10.1016/j.gene.2024.148357 (Source: Gene)
Source: Gene - March 10, 2024 Category: Genetics & Stem Cells Authors: Ramin Vosooghi Alireza Motavalizadehkakhky Atena Mansouri Jamshid Mehrzad Masood Homayouni Source Type: research

Investigating the effect of hesperetin on estrogen receptor alpha (ER α) expression, phosphorylation and activity in MCF-7 cells
CONCLUSION: Based on the results of this study, it can be concluded that hesperetin has a significant effect on ERα expression, phosphorylation and activity.PMID:38462023 | DOI:10.1016/j.gene.2024.148357 (Source: Gene)
Source: Gene - March 10, 2024 Category: Genetics & Stem Cells Authors: Ramin Vosooghi Alireza Motavalizadehkakhky Atena Mansouri Jamshid Mehrzad Masood Homayouni Source Type: research

Sensory and Pain Outcomes of Neurotized Skin-grafted Free Gracilis Muscle Flaps for Lower Extremity Reconstruction
This study prospectively analyzes the sensory and neuropathic pain outcomes of neurotized skin-grafted free gracilis muscle flaps for reconstruction of lower extremity defects. (Source: Journal of Plastic, Reconstructive and Aesthetic Surgery)
Source: Journal of Plastic, Reconstructive and Aesthetic Surgery - March 3, 2024 Category: Cosmetic Surgery Authors: Ebai A. Eseme, Katya Remy, Blandine Le Men é, Solange N. Walz, Srinivas Madduri, Carlo M. Oranges, Daniel F. Kalbermatten Source Type: research

Transcriptomics and metabolomics reveal the underlying mechanism of drought treatment on anthocyanin accumulation in postharvest blood orange fruit
Anthocyanins are the most important compounds for nutritional quality and economic values of blood orange. However, there are few reports on the pre-harvest treatment accelerating the accumulation of anthocyan... (Source: BMC Plant Biology)
Source: BMC Plant Biology - March 2, 2024 Category: Biology Authors: Hongbin Liu, Yan Jin, Le Huang, Chouyu Miao, Jiayi Tang, Huimin Zhang, Haojie Yin, Xiaopeng Lu, Na Li, Suming Dai, Alessandra Gentile, Ling Zhang and Ling Sheng Tags: Research Source Type: research

Lunar phobia, turning blue cheese red, and more stories you might have missed this week
What makes blue cheese blue? Does catching a whiff of a potential mate doom male mice to early death? And how did the Golgi apparatus evolve its weird, ribbony shape? Check out the answers below in some of our favorite selections from Science ’s daily newsletter, Science Adviser . What’s new? Blue cheeses that aren’t blue Naturally blue food is hard to find—except on a cheese platter. Roquefort, Gorgonzola, and blue Stilton are prized for their pungent tastes and characteristic blue veins. It turns out that the fungi that give these cheeses their flavors are also...
Source: Science of Aging Knowledge Environment - March 1, 2024 Category: Geriatrics Source Type: research

Naringenin Induces Cellular Apoptosis in Melanoma Cells < em > via < /em > Intracellular ROS Generation
CONCLUSION: Naringenin caused oxidative stress and mitochondrial damage, and activated autophagy in melanoma cells, leading to cell apoptosis. These findings indicate the potential of naringenin as a new therapeutic candidate for melanoma.PMID:38423648 | DOI:10.21873/anticanres.16903 (Source: Cell Research)
Source: Cell Research - February 29, 2024 Category: Cytology Authors: Pincha Devage Sameera Madushan Fernando Ao Xuan Zhen Mei Jing Piao Herath Mudiyanselage Udari Lakmini Herath Kyoung Ah Kang Sang-Pil Yoon Hye-Jin Boo Chang Lim Hyun Jin Won Hyun Source Type: research

Investigation into the role of phenolic compounds in the protection of citrus against Phyllosticta citricarpa
ConclusionNaringin, a major candidate biomarker was able to inhibit the growth of the pathogen at 10 000 ppm. (Source: Metabolomics)
Source: Metabolomics - February 26, 2024 Category: Biology Source Type: research

Development of Simplified Recombinase Polymerase Amplification Assay for Rapid and Robust Detection of Citrus Yellow Vein Clearing Virus
Curr Microbiol. 2024 Feb 22;81(4):103. doi: 10.1007/s00284-024-03614-y.ABSTRACTCitrus is an economically important fruit crop, belongs to family Rutaceae, cultivated commercially in over 130 countries, which holds a leading profitable position in the international market. The most important citrus varieties are mandarins, oranges, lemons, sweet limes, grapefruits and pomelos. Citrus yellow vein clearing virus (CYVCV) is an important graft transmissible plant pathogen known to reduce productivity of citrus fruits due to its predominant association and widespread occurrence. Requirement of fast, reliable, efficient & eco...
Source: Current Microbiology - February 22, 2024 Category: Microbiology Authors: Nitika Gupta Rakesh Kumar Gopi Kishan Susheel Kumar Sharma Nishant Srivastava Ashwini Kumar Virendra Kumar Baranwal Source Type: research

Incidentally Found Lung Cancer Following Lung Transplantation: Apples and Oranges
Ann Thorac Surg. 2024 Feb 16:S0003-4975(24)00118-8. doi: 10.1016/j.athoracsur.2024.02.014. Online ahead of print.NO ABSTRACTPMID:38369177 | DOI:10.1016/j.athoracsur.2024.02.014 (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - February 18, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Arya Pontula Connor S Spies Matthew G Hartwig Source Type: research