Fight Aging! Newsletter, December 25th 2023
This study generates a comprehensive single-cell transcriptomic atlas of human atherosclerosis including 118,578 high-quality cells from atherosclerotic coronary and carotid arteries. By performing systematic benchmarking of integration methods, we mitigated data overcorrection while separating major cell lineages. Notably, we define cell subtypes that have not been previously identified from individual human atherosclerosis scRNA-seq studies. Besides characterizing granular cell-type diversity and communication, we leverage this atlas to provide insights into smooth muscle cell (SMC) modulation. We integrate genome...
Source: Fight Aging! - December 24, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Nectandrin B Extends Life in Flies
In this study, we present evidence that Nectandrin B (NecB), a bioactive lignan compound isolated from nutmeg, significantly extended the lifespan of the fruit fly Drosophila melanogaster by as much as 42.6% compared to the control group. NecB also improved age-related symptoms including locomotive deterioration, body weight gain, eye degeneration, and neurodegeneration in aging D. melanogaster. This result represents the most substantial improvement in lifespan observed in animal experiments to date, suggesting that NecB may hold promise as a potential therapeutic agent for promoting longevity and addressing age-related d...
Source: Fight Aging! - December 22, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The Power of Spirit – Join the Event
This post is an invitation for you on multiple levels. First, there’s the human-level invitation, which you’ll get by reading the words here. I’m hosting a live event on Zoom this weekend called The Power of Spirit, and I invite you to join us for it. It will be 3 hours each day, 10:00 AM to 1:00 PM Pacific Time on October 7 and 8, 2023. The second level of this invitation is the spirit level. I’m writing this invitation while feeling very tuned in (thanks in part to a minidose of magic mushrooms this morning). As I’m writing, I can also feel some of the energy of the upcoming event flowing...
Source: Steve Pavlina's Personal Development Blog - October 6, 2023 Category: Psychiatry & Psychology Authors: Steve Pavlina Tags: Abundance Announcements Creating Reality Emotions Lifestyle Relationships Source Type: blogs

Mothing addiction and the meaning of mothing
I acquired yet another moth trap to go alongside my old second-hand, home-made Robinson with the 40W actinic UV fluorescent U-tube, the portable 20W UV fluorescent Heath, the LepiLED, and, of course, the pheromone trap for the Emperor moth and the clearwings. The day-flying Yellow-legged Clearwing moth has evolved to resemble a wasp in order to avoid predation I crammed it with the usual stock of roosting options for the moths, a load of empty cardboard egg cartons and lit up. Skinner moth trap It was 11 Celsius last night, a degree cooler than a recent lighting-up session, but the new trap brought a fairly good haul, 28 m...
Source: David Bradley Sciencebase - Songs, Snaps, Science - June 6, 2023 Category: Science Authors: David Bradley Tags: Lepidoptera Source Type: blogs

What ’ s in a name when it comes to moths?
TL:DR – It was learning some of the common names for the macro moths that helped piqued my interest in being an amateur lepidopterist and citizen science moth-er. There are around 1800 moth species seen in the UK. A large proportion of these are the so-called micro moths (which isn’t about size, but rather their position in evolutionary history) and they are usually referred to by their scientific name rather than a common name although some do have colloquial names too. But, almost all of the macro moths have an intriguing common name. Here are some of my favourites The Clifden Nonpareil (Catocala fraxini) &#...
Source: David Bradley Sciencebase - Songs, Snaps, Science - April 15, 2023 Category: Science Authors: David Bradley Tags: Lepidoptera Source Type: blogs

Goug ères
Gougères. The perfect appetizer for the holidays. So impressive, so fancy, so French. And yet, they are so easy to make. Even better, they can be made ahead and frozen, then simply reheated in the oven when your guests arrive, as they are best served warm. Gougere are simply a savory cream puff. I first learned to make cream puffs in college, when I spent my summers in the dessert kitchen of a sleep away camp in New Hampshire. My boss, whose late husband had been a French-trained chef, brought his recipes into the camp kitchen and ran the place like it was the French Laundry. She taught me how NOT to put the knives...
Source: The Blog That Ate Manhattan - December 18, 2022 Category: Primary Care Authors: Margaret Polaneczky, MD Tags: Appetizers Recipes best cream puff easy gougere Gougeres make ahead Make-ahead Source Type: blogs

Maccheroni alla bolognese
Before there was Stanley Tucci’s Searching for Italy, there was Regional Italian Cuisine, a cookbook tour of Italy’s regions through its foods and recipes. While Stanley’s show is a light aperitivo, this book is the ten course meal, with recipes for dishes that will make you feel like you’re one of the Famiglia. Each chapter of Regional Italian Cuisine focuses on a different region of Italy, summarizing in sequential, gorgeous two-page spreads of perfectly balanced text and photos its climate, crops, food specialties, regional events and sights to see. It then follows with short, well-written ...
Source: The Blog That Ate Manhattan - October 13, 2022 Category: Primary Care Authors: Margaret Polaneczky, MD Tags: Pasta Rice & Potatoes Bolognese Bolognese sauce Emilia-Romagna italian Italy Italy regional cuisine Meat sauce Ragu recipe Regional Italian Cuisine Source Type: blogs

… of all the Leps I ’ ve photographed
My Mothematics Gallery can be found on my Imaging Storm photography site along with other invertebrates, flora and fauna, etc. I’ve written about several of the species I’ve seen for various outlets, but haven’t yet got around to adding all of the links to this list #bearwith Moths Aethes francilana/beatricella (Walsingham, 1898/Fabricius, 1794) Agapeta hamana (Linnaeus, 1758) Agonopterix heracliana-ciliella agg NFM 2020 Agonopterix purpurea (Haworth, 1811) NFM 2021 (MYO lure) Angle Shades (Phlogophora meticulosa, Linnaeus, 1758) Arches, Buff (Habrosyne pyritoides, Hufnagel, 1766) Arches, Dark (Apamea m...
Source: David Bradley Sciencebase - Songs, Snaps, Science - August 10, 2021 Category: Science Authors: David Bradley Tags: Lepidoptera Source Type: blogs

21 spices for healthy holiday foods
The holiday season is one of the hardest times of the year to resist salty, fatty, sugary foods. Who doesn’t want to enjoy the special dishes and treats that evoke memories and meaning — especially during the pandemic? Physical distancing and canceled gatherings may make you feel that indulging is a way to pull some joy out of the season. But stay strong. While it’s okay to have an occasional bite or two of marbled roast beef, buttery mashed potatoes, or chocolate pie, gorging on them frequently can lead to weight gain, and increased blood pressure, blood sugar, and “bad” LDL cholesterol. Instead, skip the butter...
Source: Harvard Health Blog - December 4, 2020 Category: Consumer Health News Authors: Heidi Godman Tags: Health Healthy Eating Heart Health Inflammation Nutrition Source Type: blogs

Defusing the “Benadryl challenge”: Discussing danger with teens
Let’s start with the bottom line: Parents of teens need to help them understand that just because they have been “challenged” to do something doesn’t mean it’s a good idea. But as simple as that sounds to us, it’s tough for many teens to grasp. The latest challenge in the news is the “Benadryl challenge” that appeared on TikTok, a popular social media video platform. The idea was to take a whole lot of Benadryl (diphenhydramine, a common antihistamine) in order to cause a high, with hallucinations. While it’s true that diphenhydramine can make you high and make you hallucinate, when you take too much ...
Source: Harvard Health Blog - November 2, 2020 Category: Consumer Health News Authors: Claire McCarthy, MD Tags: Adolescent health Behavioral Health Children's Health Parenting Source Type: blogs

The new garden moths of 2020
With Covid-19 lockdown hitting some people very hard, it seems churlish to complain about its effects on me. It felt hard – no pub visits with friends, no limited time outdoors and so not much chance for nature photography and long walks with the dog, no rehearsing with C5 The Band nor the bigMouth choir, no panto to plan for etc, like I say, relatively easy, but still hard. Dark Crimson Underwing As such, I was really hoping for an exciting moth year to keep me sane, and I have had some crackers, but numbers and diversity seem to have been low…all I’ve really seen for the last couple of weeks are quite a...
Source: David Bradley Sciencebase - Songs, Snaps, Science - September 14, 2020 Category: Science Authors: David Bradley Tags: Lepidoptera Sciencebase Source Type: blogs

The garden moths of 2020
With Covid-19 lockdown hitting some people very hard, it seems churlish to complain about its effects on me. It felt hard – no pub visits with friends, no limited time outdoors and so not much chance for nature photography and long walks with the dog, no rehearsing with C5 The Band nor the bigMouth choir, no panto to plan for etc, like I say, relatively easy, but still hard. Dark Crimson Underwing As such, I was really hoping for an exciting moth year to keep me sane, and I have had some crackers, but numbers and diversity seem to have been low…all I’ve really seen for the last couple of weeks are quite a...
Source: David Bradley Sciencebase - Songs, Snaps, Science - September 14, 2020 Category: Science Authors: David Bradley Tags: Lepidoptera Sciencebase Source Type: blogs

How to identify British Moths
Sean Foote is a marvel. Over on Twitter he responds to tagged tweets from people who have photographed a UK moth or two and would like to know what species of moth they have. I’ve used his services on numerous occasions often to confirm an identification, but more often when I simply didn’t have a clue as a relative n00B moth-er. It’s an entirely free service although users can “buy him a coffee” here as a mark of appreciation. He keeps records, as you would, and publishes details of the most requested identifications, he’s also got a nice Top 100 with tips on how to identify some of the...
Source: David Bradley Sciencebase - Songs, Snaps, Science - July 23, 2020 Category: Science Authors: David Bradley Tags: Lepidoptera Source Type: blogs

How my dog helps motivate me to manage my high cholesterol
This post is sponsored by Kowa Pharmaceuticals America, Inc. Personal opinions and thoughts are my own. As a wellness author and speaker, people often ask me questions about cholesterol and heart disease.  In partnership with Take Cholesterol to Heart, I’m answering some of the most common questions. Want to learn more? Be sure to visit Take Cholesterol to Heart for more information on managing your cholesterol levels. Q: I know that exercise is an important piece of a cholesterol management plan, but I find it hard to get motivated. Do you have any advice? A: Yes! As the video below shows, partnering with an enthusias...
Source: Embrace Your Heart Wellness Initiative - October 29, 2019 Category: Cardiology Authors: Eliz Greene Tags: Exercise Tips Heart Disease Risk Factors Heart Health cholesterol Take Cholesterol To Heart Source Type: blogs

Lepidoptera first showing 2019
First appearances in 2019 of various moth species to the scientific trap. Some of these were new for the year (NFY) as I’d seen them in 2018. Some were NFM, new for me. 15 Sep Clepsis consimilana 15 Sep Beautiful Hook-tip 13 Sep Brown-spot Pinion 13 Sep Barred Sallow 10 Sep Common Marble 7 Sep Centre-barred Sallow 4 Sep Feathered Gothic 4 Sep Eudonia angustea 3 Sep Yellow-line Quaker 25 Aug Frosted Orange 25 Aug Jersey Tiger 7 Aug Straw Underwing 6 Aug White-spotted Pinion 5 Aug The Lychnis 5 Aug Rosy Rustic 5 Aug Wax Moth 4 Aug Twin-spotted Wainscot 4 Aug Pale Prominent 4 Aug Flounced Rustic 4 Aug Red Underwing 30 J...
Source: David Bradley Sciencebase - Songs, Snaps, Science - September 16, 2019 Category: Science Authors: David Bradley Tags: Sciencebase Source Type: blogs