Emerging zoonotic diseases in Southeast Asia in the period 2011-2022: a systematic literature review
Vet Q. 2024 Dec;44(1):1-15. doi: 10.1080/01652176.2023.2300965. Epub 2024 Jan 16.ABSTRACTAs COVID-19 has shown, pandemics and outbreaks of emerging infections such as Zika, Nipah, monkeypox and antimicrobial-resistant pathogens, especially emerging zoonotic diseases, continue to occur and may even be increasing in Southeast Asia. In addition, these infections often result from environmental changes and human behaviour. Overall, public health surveillance to identify gaps in the literature and early warning signs are essential in this region. A systematic review investigated the prevalence of emerging zoonotic diseases over...
Source: Veterinary Quarterly - January 17, 2024 Category: Veterinary Research Authors: Thanh Trung Nguyen Thi Ngan Mai Sinh Dang-Xuan Hung Nguyen-Viet Fred Unger Hu Suk Lee Source Type: research

Outcome and Sequelae of Infectious Encephalitis
J Clin Neurol. 2024 Jan;20(1):23-36. doi: 10.3988/jcn.2023.0240.ABSTRACTAcute infectious encephalitis is a widely studied clinical syndrome. Although identified almost 100 years ago, its immediate and delayed consequences are still neglected despite their high frequency and possible severity. We reviewed the available data on sequelae and persisting symptoms following infectious encephalitis with the aim of characterizing the clinical picture of these patients at months to years after hospitalization. We searched PubMed for case series involving sequelae after infectious encephalitis. We carried out a narrative review of t...
Source: Journal of Clinical Neurology - January 5, 2024 Category: Neurology Authors: Kathryn A Kvam Jean-Paul Stahl Felicia C Chow Ariane Soldatos Pierre Tattevin James Sejvar Alexandra Mailles Source Type: research

Outcome and Sequelae of Infectious Encephalitis
J Clin Neurol. 2024 Jan;20(1):23-36. doi: 10.3988/jcn.2023.0240.ABSTRACTAcute infectious encephalitis is a widely studied clinical syndrome. Although identified almost 100 years ago, its immediate and delayed consequences are still neglected despite their high frequency and possible severity. We reviewed the available data on sequelae and persisting symptoms following infectious encephalitis with the aim of characterizing the clinical picture of these patients at months to years after hospitalization. We searched PubMed for case series involving sequelae after infectious encephalitis. We carried out a narrative review of t...
Source: Herpes - January 5, 2024 Category: Infectious Diseases Authors: Kathryn A Kvam Jean-Paul Stahl Felicia C Chow Ariane Soldatos Pierre Tattevin James Sejvar Alexandra Mailles Source Type: research

Outcome and Sequelae of Infectious Encephalitis
J Clin Neurol. 2024 Jan;20(1):23-36. doi: 10.3988/jcn.2023.0240.ABSTRACTAcute infectious encephalitis is a widely studied clinical syndrome. Although identified almost 100 years ago, its immediate and delayed consequences are still neglected despite their high frequency and possible severity. We reviewed the available data on sequelae and persisting symptoms following infectious encephalitis with the aim of characterizing the clinical picture of these patients at months to years after hospitalization. We searched PubMed for case series involving sequelae after infectious encephalitis. We carried out a narrative review of t...
Source: Journal of Clinical Neurology - January 5, 2024 Category: Neurology Authors: Kathryn A Kvam Jean-Paul Stahl Felicia C Chow Ariane Soldatos Pierre Tattevin James Sejvar Alexandra Mailles Source Type: research

Outcome and Sequelae of Infectious Encephalitis
J Clin Neurol. 2024 Jan;20(1):23-36. doi: 10.3988/jcn.2023.0240.ABSTRACTAcute infectious encephalitis is a widely studied clinical syndrome. Although identified almost 100 years ago, its immediate and delayed consequences are still neglected despite their high frequency and possible severity. We reviewed the available data on sequelae and persisting symptoms following infectious encephalitis with the aim of characterizing the clinical picture of these patients at months to years after hospitalization. We searched PubMed for case series involving sequelae after infectious encephalitis. We carried out a narrative review of t...
Source: Herpes - January 5, 2024 Category: Infectious Diseases Authors: Kathryn A Kvam Jean-Paul Stahl Felicia C Chow Ariane Soldatos Pierre Tattevin James Sejvar Alexandra Mailles Source Type: research

Outcome and Sequelae of Infectious Encephalitis
J Clin Neurol. 2024 Jan;20(1):23-36. doi: 10.3988/jcn.2023.0240.ABSTRACTAcute infectious encephalitis is a widely studied clinical syndrome. Although identified almost 100 years ago, its immediate and delayed consequences are still neglected despite their high frequency and possible severity. We reviewed the available data on sequelae and persisting symptoms following infectious encephalitis with the aim of characterizing the clinical picture of these patients at months to years after hospitalization. We searched PubMed for case series involving sequelae after infectious encephalitis. We carried out a narrative review of t...
Source: Journal of Clinical Neurology - January 5, 2024 Category: Neurology Authors: Kathryn A Kvam Jean-Paul Stahl Felicia C Chow Ariane Soldatos Pierre Tattevin James Sejvar Alexandra Mailles Source Type: research

Outcome and Sequelae of Infectious Encephalitis
J Clin Neurol. 2024 Jan;20(1):23-36. doi: 10.3988/jcn.2023.0240.ABSTRACTAcute infectious encephalitis is a widely studied clinical syndrome. Although identified almost 100 years ago, its immediate and delayed consequences are still neglected despite their high frequency and possible severity. We reviewed the available data on sequelae and persisting symptoms following infectious encephalitis with the aim of characterizing the clinical picture of these patients at months to years after hospitalization. We searched PubMed for case series involving sequelae after infectious encephalitis. We carried out a narrative review of t...
Source: Herpes - January 5, 2024 Category: Infectious Diseases Authors: Kathryn A Kvam Jean-Paul Stahl Felicia C Chow Ariane Soldatos Pierre Tattevin James Sejvar Alexandra Mailles Source Type: research

Outcome and Sequelae of Infectious Encephalitis
J Clin Neurol. 2024 Jan;20(1):23-36. doi: 10.3988/jcn.2023.0240.ABSTRACTAcute infectious encephalitis is a widely studied clinical syndrome. Although identified almost 100 years ago, its immediate and delayed consequences are still neglected despite their high frequency and possible severity. We reviewed the available data on sequelae and persisting symptoms following infectious encephalitis with the aim of characterizing the clinical picture of these patients at months to years after hospitalization. We searched PubMed for case series involving sequelae after infectious encephalitis. We carried out a narrative review of t...
Source: Journal of Clinical Neurology - January 5, 2024 Category: Neurology Authors: Kathryn A Kvam Jean-Paul Stahl Felicia C Chow Ariane Soldatos Pierre Tattevin James Sejvar Alexandra Mailles Source Type: research

Construction of a recombinant vaccine expressing Nipah virus glycoprotein using the replicative and highly attenuated vaccinia virus strain LC16m8
In this study, we generated recombinant vaccinia viruses expressing the NiV glycoprotein (G) or fusion (F) protein using the LC16m8 strain, and examined their antigenicity and ability to induce immunity. Neutralizing antibodies against NiV were successfully induced in hamsters inoculated with LC16m8 expressing NiV G or F, and the antibody titers were higher than those induced by other vaccinia virus vectors previously reported to prevent lethal NiV infection. These findings indicate that the LC16m8-based vaccine format has superior features as a proliferative vaccine compared with other poxvirus-based vaccines. Moreover, t...
Source: PLoS Neglected Tropical Diseases - December 15, 2023 Category: Tropical Medicine Authors: Shumpei Watanabe Source Type: research

Viruses, Vol. 15, Pages 2407: Recently Emerged Novel Henipa-like Viruses: Shining a Spotlight on the Shrew
rds Henipaviruses are zoonotic viruses, including some highly pathogenic and capable of serious disease and high fatality rates in both animals and humans. Hendra virus and Nipah virus are the most notable henipaviruses, resulting in significant outbreaks across South Asia, South-East Asia, and Australia. Pteropid fruit bats have been identified as key zoonotic reservoirs; however, the increased discovery of henipaviruses outside the geographic distribution of Pteropid fruit bats and the detection of novel henipa-like viruses in other species such as the shrew, rat, and opossum suggest that Pteropid bats are not the so...
Source: Viruses - December 11, 2023 Category: Virology Authors: Sarah Caruso Sarah J. Edwards Tags: Review Source Type: research

EPH101 Assessing the Relative Benefits Associated With Developing Vaccines for Nipah Virus Infection and Rift Valley Fever From Local, National, and Global Perspectives
Vaccination is a vital component of public health policy though there are many diseases for which vaccines are not available. Global health-care organizations with limited resources must make difficult choices over which vaccines to develop and where to deploy them. Here we provide a comparison between Nipah Virus Infection (NPI) and Rift Valley Fever (RVF), two diseases that have been prioritized by the WHO for R&D in public health emergency contexts. (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: R. Gani, A. Pinsent, R. Chapman Source Type: research

Rebuilding for Tomorrow ’s Outbreak: The State of Special Pathogen Preparedness in the USA in the Wake of COVID-19
AbstractPurpose of ReviewSpecial pathogens require unique planning care capabilities within healthcare facilities and can pose significant public health threats. Outbreaks have continued to emerge through the COVID-19 pandemic and serve as reminders of the need to have tiered levels of readiness and resources supporting all healthcare settings.Recent FindingsRecent outbreaks of Marburg virus, Sudan virus, Lassa virus, and Nipah virus are examples of low-incidence pathogens that carry disproportionally high potential consequences for healthcare worker safety and public health. While the COVID-19 pandemic has increased aware...
Source: Current Infectious Disease Reports - December 1, 2023 Category: Infectious Diseases Source Type: research

Pangenomic and immunoinformatics based analysis of Nipah virus revealed CD4+ and CD8+ T-Cell epitopes as potential vaccine candidates
Conclusion: Our vaccinomics and system-level investigation could help to trigger the host immune system to prevent NiV infection. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - November 14, 2023 Category: Drugs & Pharmacology Source Type: research