National Institute for Health Research (NIHR) Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Correction to: Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses
Edward J. Needham, Alexander L. Ren, Richard J. Digby, Emma J. Norton, Soraya Ebrahimi, Joanne G. Outtrim, Doris A. Chatfield, Anne E. Manktelow, Maya M. Leibowitz, Virginia F. J. Newcombe, Rainer Doffinger, Gabriela Barcenas-Morales, Claudia Fonseca, Michael J. Taussig, Rowan M. Burnstein, Romit J. Samanta, Cordelia Dunai, Nyarie Sithole, Nicholas J. Ashton, Henrik Zetterberg, Magnus Gissl én, Arvid Edén, Emelie Marklund, Peter J. M. Openshaw, Jake Dunning, Michael J. Griffiths, Jonathan Cavanagh, Gerome Breen, Sarosh R. Irani, Anne Elmer, Nathalie Kingston, Charlotte Summers, John R. Bradley, Leonie S. Taams, Benedict ...
Source: Brain - November 6, 2023 Category: Neurology Source Type: research

PROphylaxis for vulnerable paTiEnts at risk of COVID-19 infecTion (PROTECT-V) - Sotrovimab arm
DiscussionEffective prophylactic interventions against SARS-CoV-2 will protect vulnerable patients with suboptimal vaccine responses and improve their quality of life. The PROTECT-V platform is jointly funded from charitable (LifeArc, Kidney Research UK, Addenbrooke’s Charitable Trust), government (NIHR), and industry (GSK/Vir for the sotrovimab arm) sources and focuses on patient groups often excluded from clinical trials but remain vulnerable to SARS-CoV-2 infection despite successful vaccination. It is planned to recruit a minimum of 1760 participants to the sotrovimab arm. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Crowley, L., Chen-Xu, M., Dowling, F., Qian, W., Adhikari, R., Griffiths, D., Bruce, E., Han, J., Smith, R., Dosanjh, D. Tags: Respiratory infections and bronchiectasis Source Type: research

Rehabilitation outcomes for an exercise based multi-morbid rehabilitation programme - a survey of healthcare professionals
Conclusion: A collection of outcome have been identified to assess feasibility of the PERFORM intervention.PERFORM is funded by an NIHR Programme Grant (202020). (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Singh, S. J., Smith, S., Mair, F., Evans, R., Daw, P., Greaves, C., Simpson, S., Taylor, R. Tags: Rehabilitation and chronic care Source Type: research

An overview of systematic reviews of exercise-based interventions for people with long-term conditions
Conclusion: LTC identified with clear indications for exercise-based interventions will inform the population for inclusion in the NIHR funded Personalised Exercise Rehabilitation FOR people with Multiple LTC (PERFORM) research programme; aiming to develop and evaluate a rehabilitation intervention for people living with multiple LTC. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Gardiner, L., Dibben, G. O., Young, H. M. L., Singh, S., Taylor, R. S., Collaborative Group, P. Tags: Rehabilitation and chronic care Source Type: research

The Relationship Between Motor Competence Physical Activity Cardiorespiratory Fitness and BMI in UK Adolescents
. (Source: Research Quarterly for Exercise and Sport)
Source: Research Quarterly for Exercise and Sport - October 24, 2023 Category: Sports Medicine Authors: Benjamin David WeedonPatrick EsserJohnny CollettHooshang IzadiShawn JoshiAndy MeaneyAnne DelextratSteve KempHelen Dawesa Oxford Brookes Universityb Drexel Universityc Oxfordshire Sports Partnershipd University of Exetere NIHR Exeter Biomedical Research Ce Source Type: research

Understanding what affects psychological morbidity in informal carers when providing care at home for patients at the end of life: a systematic qualitative evidence synthesis
CONCLUSIONS AND FUTURE WORK: A wide range of both internal and contextual factors may lead to psychological morbidity when caring for someone at the end of life. Future work within practice therefore requires a broad-based rather than narrow approach to sustaining and improving carer mental health. Future work within research requires collaboration between researchers and stakeholders within policy, commissioning, practice and carer organisations to develop solutions and assess their effectiveness. Further, researchers need to develop better models for factors affecting carer mental health and their interaction, to build a...
Source: Cancer Control - October 16, 2023 Category: Cancer & Oncology Authors: Kerin Bayliss Tracey Shield Alison Wearden Jackie Flynn Christine Rowland Penny Bee Morag Farquhar Danielle Harris Alexander Hodkinson Maria Panagioti Margaret Booth David Cotterill Lesley Goodburn Cedric Knipe Gunn Grande Source Type: research

Genetic screening for pathogenic variants in type 2 diabetes of the Arab Gulf population: A systematic review and meta-analysis
ConclusionFor a better understanding of the molecular etiology of T2DM, finding SNPs, and establishing a meaningful genotype-phenotype connection for complicated diabetic disorders, the cumulative relevance of identified pathogenic SNPs in Arab Gulf was shown. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - October 11, 2023 Category: Endocrinology Source Type: research

Effects of reduced-risk nicotine-delivery products on smoking prevalence and cigarette sales: an observational study
CONCLUSIONS: We detected some indications that alternative nicotine products are competing with cigarettes rather than promoting smoking and that regulations that allow their sales are associated with a reduction rather than an increase of smoking, but the findings are inconclusive because of insufficient data points and issues with the assumptions of the pre-specified statistical analyses.FUTURE WORK: As further prevalence and sales data emerge the analyses will become more informative. Accessing sales figures in particular is the current research priority.STUDY REGISTRATION: The project is registered on Open Science Fram...
Source: Cancer Control - October 5, 2023 Category: Cancer & Oncology Authors: Francesca Pesola Anna Phillips-Waller Emma Beard Lion Shahab David Sweanor Martin Jarvis Peter Hajek Source Type: research

Using the making Visible the ImpaCT Of Research (VICTOR) questionnaire to evaluate the benefits of a fellowship programme for nurses, midwives and allied health professionals
CONCLUSION: There were some challenges with the fellowship programme, but all recipients found it to be a positive experience and undertook significant scholarly activity.IMPLICATIONS FOR PRACTICE: A contractual agreement must be established to foster committed partnerships between higher education institutions (HEIs) and the NHS. HEIs and the NHS should conduct frank discussions of the challenges encountered in fellowship programmes. Positive initiatives and outcomes in tertiary education and clinical settings should be shared to improve fellows' experiences and enhance partnerships between HEIs and the NHS. Job descripti...
Source: Nurse Researcher - October 5, 2023 Category: Nursing Authors: Carolyn Spring Julie Hogg Judith Holliday Jo Cooke Rachel M Taylor Source Type: research