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Researching long COVID: addressing a new global health challenge, NIHR
Long COVID is a new disease with many unanswered questions. This uncertainty creates huge challenges for patients and clinicians. To date, more than £ 50 million of government funding has been invested in long COVID research projects. The bulk of this ( £ 39.2 million) has been awarded to 19 projects commissioned through two specific calls. The calls were led by the NIHR, the first jointly with UKRI. Projects examine the underlying mechanisms of long COVID, investigate symptoms such as ' brain fog ' and breathlessness, and test possible treatments. They explore whether NHS services, such as long COVID clinics, meet peop...
Source: Current Awareness Service for Health (CASH) - May 12, 2022 Category: Consumer Health News Source Type: news

People hospitalised with severe COVID-19 show cognitive decline similar to 20 years of ageing, NIHR
New research funded by NIHR shows that patients who were hospitalised with severe COVID have lasting cognitive problems several months after their acute illness. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 10, 2022 Category: Consumer Health News Source Type: news

Cognitive impairment from severe COVID-19 equivalent to 20 years of ageing, study finds
Cognitive impairment as a result of severe COVID-19 is similar to that sustained between 50 and 70 years of age and is the equivalent to losing 10 IQ points, say a team of scientists from the University of Cambridge and Imperial College London. The findings, published in the journal eClinicalMedicine, emerge from the NIHR COVID-19 BioResource. (Source: World Pharma News)
Source: World Pharma News - May 3, 2022 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Frail older people and those living in deprived areas remain at risk from COVID-19, even after vaccination, NIHR Evidence
Vaccination against COVID-19 is highly successful at reducing severe illness and death in the population, but people still get infected after vaccination. New research also shows that frail older people, and those who live in deprived areas, are more at risk of infection after vaccination than other groups. The researchers urge family and friends to remain cautious around these vulnerable groups of people. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - April 29, 2022 Category: Consumer Health News Source Type: news

NIHR Alert: Frail older people and those living in deprived areas remain at risk from COVID-19, even after vaccination, NIHR Dissemination Centre
Commentaries provided on new research based on COVID-19 Symptom Study app (ZOE) that showed frail older people& those who live in deprived areas, are more at risk of infection after vaccination than other groups. They may be more affected by lifting of infection control measures (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - April 29, 2022 Category: Consumer Health News Source Type: news

Researchers create new tool to assess symptoms of long COVID, NIHR
Researchers have worked with patients to develop a comprehensive tool to assess the symptoms of long COVID and their impact on everyday life. Around 1.7 million people in the UK, and more than 100 million people worldwide, continue to experience symptoms more than four weeks after having COVID-19, a condition known as long COVID. Currently more than 200 symptoms affecting many organs in the body are associated with long COVID, including breathlessness, fatigue and brain fog. Healthcare providers and researchers need reliable ways of measuring these symptoms and how they are experienced by patients, to help them develop n...
Source: Current Awareness Service for Health (CASH) - April 28, 2022 Category: Consumer Health News Source Type: news

COVID-19 vaccine boosters give well-maintained immunity three months on, finds NIHR-supported COV-BOOST trial, NIHR
The latest results from the UK ' s COV-BOOST study, led by University Hospital Southampton, have shown prolonged immune responses following third doses of several COVID-19 vaccines. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - April 28, 2022 Category: Consumer Health News Source Type: news

NIHR Alert: Emergency care in hospitals is as good at the weekend as on weekdays, NIHR Dissemination Centre
Commentaries provided on study that disproves common belief hospital care of emergency admissions is poorer at weekends, providing reassurance people admitted then will not receive poorer care than during the week. ' Weekend effect ' was caused by lack of services in the community. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - April 19, 2022 Category: Consumer Health News Source Type: news

Antiviral treatment Paxlovid investigated through PANORAMIC study, NIHR
PANORAMIC is a nationwide platform trial, set up to rapidly investigate a range of new COVID-19 antiviral treatments that can be taken at home, in the early stages of infection, to help people recover more quickly and reduce the risk of serious illness from the virus. In just over three months, more than 23,000 patients have enrolled into the study for a chance to access molnupiravir, the first antiviral to be made available. The introduction of Paxlovid will allow a further 17,500 patients to enrol for a chance of accessing this groundbreaking treatment, which has been shown to reduce the risk of death or hospitalisation ...
Source: Current Awareness Service for Health (CASH) - April 14, 2022 Category: Consumer Health News Source Type: news

The perfect storm: How COVID-19 public health messages may not serve ethnic minority communities, NIHR
Research has uncovered how historical and contemporary injustice and institutional mistrust influenced how public health information was received by ethnic minority communities during the COVID-19 pandemic. Professor Tushna Vandrevala describes how important it is to get government messaging right and the advice from her research on creating inclusive and effective health behaviour communications. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 31, 2022 Category: Consumer Health News Source Type: news

Covid-19 mixed with flu increases risk of severe illness and death, NIHR
Patients in hospital with both COVID-19 and flu are at much greater risk of severe disease and death, new NIHR-funded and supported research shows. The findings, from a study carried out by the University of Edinburgh, University of Liverpool, Leiden University and Imperial College London, show patients who were infected with SARS-CoV-2 (the virus which causes COVID-19) and influenza at the same time were over four times more likely to require ventilation support and 2.4 times more likely to die than if they only had COVID-19. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 31, 2022 Category: Consumer Health News Source Type: news

RECOVERY Trial shows baricitinib reduces deaths in COVID-19 hospitalised patients, NIHR
The NIHR-supported RECOVERY trial has found that baricitinib, an anti-inflammatory rheumatoid arthritis drug, reduces deaths in patients hospitalised for COVID-19 by around one-fifth. The benefit was in addition to those of dexamethasone and tocilizumab, two other anti-inflammatory treatments which have previously been shown to reduce the risk of death in these patients. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 17, 2022 Category: Consumer Health News Source Type: news

NIHR Alert: Why don't children and young people engage with diabetes services?, NIHR Dissemination Centre (published 15th March 2022)
Expert commentaries are provided on a study of 22 young people with diabetes, which found stigma, faith-based identity,& support in schools were factors in engagement with diabetes services. A set of bespoke toolkits, to improve engagement for disadvantaged young people may help (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 17, 2022 Category: Consumer Health News Source Type: news

Genetic study gives further details into severe COVID-19, NIHR
The NIHR-supported GenOMICC study, the world ' s largest study of the genetics of critical COVID-19, has revealed details about some of the biological mechanisms behind the severe form of the disease Involving more than 57,000 people, the trial has discovered 16 new genetic variants associated with severe COVID-19, including some related to blood clotting, immune response and intensity of inflammation. These findings will act as a roadmap for future efforts, opening new fields of research focused on potential new therapies and diagnostics with pinpoint accuracy. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 10, 2022 Category: Consumer Health News Source Type: news

Cochrane-REWARD prize: winners announced
We are pleased to share the winners of the 2021 Cochrane-REWARD prize.The Cochrane-REWARD prize recognizes successful local or pilot initiatives that have potential to reduce research waste globally if scaled up. Cochrane has funded the prize since it began in 2017. For this iteration of the prize, submissions related to tackling research waste relevant to COVID-19 were encouraged.The prize ceremony took place on 1 March virtually (recordings are available below). Two representatives of the prize committee – Matt Westmore, Chief Executive of theUK Health Research Authority, and Lex Bouter, Professor of Methodology and In...
Source: Cochrane News and Events - March 2, 2022 Category: Information Technology Authors: Lydia Parsonson Source Type: news