NIHR Signal: Patients, in theory, might prefer GP-led care to self-management for high blood pressure
Expert commentary is provided for a survey (n=167) which found GP management was preferred to self-care, but there was little difference between GP care, telehealth and pharmacist care. This preference suggests limitations on the uptake of self-management strategies. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - November 21, 2019 Category: Consumer Health News Source Type: news

NIHR Signal: A workplace voucher reward scheme failed to boost physical activity
Cluster RCT (n=853) found that although steps per day increased with an incentive scheme (vouchers redeemable at local businesses), there was no significant difference in physical activity by 12 months. New approaches to reduce prolonged sitting are needed. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - November 21, 2019 Category: Consumer Health News Source Type: news

NIHR Signal: Planned earlier delivery for late pre-eclampsia may be better for mothers
Expert commentary is provided for an RCT (n=448) which found that babies born in the planned delivery arm were born on average 5 days earlier, but that death, or neonatal unit admission was higher in planned delivery vs expectant management (RR 1.26, 95% CI 1.08-1.47). (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - November 21, 2019 Category: Consumer Health News Source Type: news

Herpes zoster vaccine reduces chances of shingles after stem cell transplants
This NIHR Signal says that the risk of shingles is about 10% per year in adults after autologous stem cell transplant. The evidence summary indicates that two doses of deactivated herpes zoster vaccine could be a safe and effective way to reduce that risk by about two thirds.This effect is similar to another, heat-treated, non-live vaccine. Either vaccine could reduce the pain and need for medical treatment associated with shingles, and long-lasting complications such as post-herpetic neuralgia. It ' s not yet known if people need to continue taking acyclovir as well. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - November 20, 2019 Category: Consumer Health News Source Type: news

Better strategies are needed to reduce preventable patient harm in healthcare
This NIHR-funded review pooled data from observational studies carried out around the world. It was not possible to identify completely accurate rates of incidents and harm, due to differences in healthcare systems, and the methods and timeframes for reporting and analysing data. However, this well-conducted review provides the best evidence so far about the proportion of overall patient harm that could be prevented. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 30, 2019 Category: Consumer Health News Source Type: news

MRC and NIHR join forces to support GACD projects
MRC and NIHR have joined forces to invest over£6m in five implementation science projects focused on tackling diabetes and hypertension in low- and middle-income countries, under the Global Alliance for Chronic Diseases. (Source: Medical Research Council General News)
Source: Medical Research Council General News - October 23, 2019 Category: Research Source Type: news

2019 Cochrane-REWARD Prize winners announced
We are pleased to announce the winners – one first place and two runners-up – of this year’s Cochrane-REWARD Prize. The Cochrane-REWARD Prize recognizes successful local or pilot initiatives that have potential to reduce research waste globally if scaled up. Cochrane has funded the prize annually since it began in 2017.The prize ceremony took place on Wednesday 9 October at the International Clinical Trials Methodology Conference in Brighton, UK. Dr Joan Marsh, Deputy Editor of The Lancet Psychiatry and member of the prize committee, was there to hand out the prizes. During the conference, each recipient also had the...
Source: Cochrane News and Events - October 18, 2019 Category: Information Technology Authors: Lydia Parsonson Source Type: news

NIHR Signal: C-reactive protein testing in general practice safely reduces antibiotic use for COPD flare-ups
Expert opinion is provided of a study which concludes rapid point-of-care CRP testing for patients presenting with an exacerbation of COPD may help with antibiotic stewardship, without compromising patient outcomes/safety, and the findings are likely to influence future guidance. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 26, 2019 Category: Consumer Health News Source Type: news

NIHR Signal: Packages of care interventions'not effective' to reduce repeat admissions for COPD
An expert commentary on this study suggests that care bundles are only likely to work if they are actually implemented, though this is likely to require additional resources and additional prioritisation of care for this group of patients. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 3, 2019 Category: Consumer Health News Source Type: news

NIHR Signal: closer links between police and health services can improve experiences for people in mental health crisis
An expert commentary is provided of this rapid evidence synthesis; which found tighter working partnerships between health professionals& police services are likely to improve the care of people who come into contact with police during mental health crises. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 3, 2019 Category: Consumer Health News Source Type: news

£ 1.8 million for trial to evaluate treatment for chronic severe low back pain
Researchers at the University of Bristol, in collaboration with North Bristol NHS Trust, the Universities of Keele and Southampton have been awarded £ 1.8 million from the National Institute of Health Research (NIHR) to evaluate a treatment for chronic severe low back pain. Led by Dr Vikki Wylde, the RADICAL study will be a randomised controlled trial to find out if radiofrequency denervation, a procedure commonly used in the NHS, can provide pain relief. (Source: University of Bristol news)
Source: University of Bristol news - September 2, 2019 Category: Universities & Medical Training Tags: Health; Faculty of Health Sciences, Faculty of Health Sciences, Bristol Medical School Source Type: news

NIHR Signal: Adding behavioural support to drug treatment helps more people quit smoking
Expert commentary is provided of updated Cochrane review which found that among people using drug treatment to stop smoking, adding telephone or face-to-face behavioural support boosts their chances of success (17 to 20%) after ≥ 6 months. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - August 27, 2019 Category: Consumer Health News Source Type: news

An Open Letter in Response to the FDA ’s Public Comment Request on the Clinical Data Summary Report Pilot
This post was originally posted on the Cochrane Methods websiteIn January 2018, the FDAannounced a pilot aimed at enhancing the transparency of the Agency ' s drug approval process and decisions. As part of the pilot, sponsors of up to nine drug applications to the FDA were asked, on a voluntary basis, if they would approve the public release of portions of the CSRs, which would be posted within an Action Package for the drug that also includes FDA application review files and letters. The parts of the CSRs made publicly available included information from the study report body, the protocol and amendments, and the statist...
Source: Cochrane News and Events - August 22, 2019 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Antibiotics reduce complications after assisted vaginal delivery
Antibiotics are not routinely recommended for women undergoing assisted delivery as there hasn ' t been enough evidence that they reduce maternal infection rates. This large NIHR-funded trial, including almost 3,500 women from across the UK, provides compelling evidence that they do. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - August 19, 2019 Category: Consumer Health News Source Type: news