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NEWS2 evaluated for prediction of severe COVID-19 outcome in large international study
(NIHR Maudsley Biomedical Research Centre) In the first systematic large-scale evaluation of the UK National Early Warning Risk Score (NEWS) 2 as a scoring system for predicting severe COVID-19 outcomes in patients, researchers at King's College London have found poor-to-moderate accuracy for identifying patients at risk of being transferred to intensive care units (ICUs) or dying after 14 days of hospitalisation. Accuracy of predictions in short term (three days) showed moderate success. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 20, 2021 Category: International Medicine & Public Health Source Type: news

Successive governments' approach to obesity policies has destined them to fail
(University of Cambridge) Government obesity policies in England over the past three decades have largely failed because of problems with implementation, lack of learning from past successes or failures, and a reliance on trying to persuade individuals to change their behaviour rather than tackling unhealthy environments. This is the conclusion of new research by a team at the University of Cambridge funded by the NIHR School for Public Health Research. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 18, 2021 Category: International Medicine & Public Health Source Type: news

Arthritis drugs effective in improving survival in sickest COVID-19 patients, NIHR
Results from the REMAP-CAP clinical trial evaluated the effect of treatments on a combination of survival and length of time patients need support in an intensive care unit (ICU). Patients receiving tocilizumab and a second drug called sarilumab - both types of immune modulators - have a significant impact on patient survival and can reduce the relative risk of death by 24% when administered to patients within 24 hours of entering intensive care. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 14, 2021 Category: Consumer Health News Source Type: news

Lockdown raised anxiety in people with anorexia and their carers, but online resources helped, NIHR Evidence
The lockdowns and restrictions during the COVID-19 pandemic disrupted eating disorder services. People with anorexia nervosa experienced a loss of routine, heightened anxieties, and increased symptoms. Carers felt more concern and greater responsibility for their loved ones. Despite these difficulties, some patients and carers benefitted from digital self-management resources. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 14, 2021 Category: Consumer Health News Source Type: news

Informal dementia carers had to make difficult decisions about paid care during COVID-19, NIHR Evidence
People living with dementia in the community typically rely on unpaid care from friends and family members, combined with some paid care. This helps them remain in their own homes. Researchers wanted to find out how the first nationwide COVID-19 lockdown affected unpaid carers, and how they made decisions about accessing paid care. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 14, 2021 Category: Consumer Health News Source Type: news

How sure would you want to be that you have coeliac disease before starting a gluten-free diet?
A new survey from researchers at NIHR ARC West and the University of Bristol has been launched to understand how sure people want to be that they ’ ve got coeliac disease before starting a gluten-free diet. (Source: University of Bristol news)
Source: University of Bristol news - January 14, 2021 Category: Universities & Medical Training Tags: Health, Research; Faculty of Health Sciences, Faculty of Health Sciences, Population Health Sciences; Press Release Source Type: news

Concerning drop in the number of people with mental health problems seeking help revealed
(NIHR Greater Manchester Patient Safety Translational Research Centre) During April 2020, while the UK was in full lockdown, there was a drop of more than a third in the number of people seeking help for mental illness or self-harm according to research involving 14 million people registered at general practices across the four nations of the UK which was published today in The Lancet Public Health. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - January 11, 2021 Category: International Medicine & Public Health Source Type: news

Cochrane ENT seeks full-time Systematic Reviewer - Oxford, UK or UK remote
Closing date: 19 April 2021 Location: Oxford, UK or remote working from UKCochrane ENT is looking for an experienced Systematic Reviewer to work with the Cochrane ENT team, based atCochrane UK in Oxford. The main purpose of the role is to facilitate the completion of high-priority systematic reviews being undertaken as parts of suites of reviews on priority topics, funded by a NIHR Programme Grant. The post-holder will also assist Cochrane ENT with other discrete systematic review tasks for a range of projects, as required. You will be working closely with the Cochrane ENT editorial team and the main duties of the post...
Source: Cochrane News and Events - December 16, 2020 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Vertical integration of GP practices with acute hospitals in England and Wales: rapid evaluation
This report, commissioned by the National Institute for Health Research and undertaken together with the Health Services Management Centre at the University of Birmingham and the Health Services Research Group at the University of Cambridge, evaluates what has led to this kind of vertical integration in England and Wales, how it has been implemented, and with what consequences. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - December 4, 2020 Category: Consumer Health News Source Type: news

NIHR alert: The WHELD programme for people with dementia helps care home staff deliver person-centred care
Expert commentary is provided on a UK study that found the WHELD programme, which supports care home staff to deliver patient-centred interventions for residents with dementia and reduce reliance on antipsychotics, was effective and cost less to deliver than usual care. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - November 27, 2020 Category: Consumer Health News Source Type: news

Johnson & Johnson Initiates Second Global Phase 3 Clinical Trial of its Janssen COVID-19 Vaccine Candidate
November 15, 2020 -- The Phase 3 ENSEMBLE study of the single-dose regimen of JNJ-78436735, the investigational vaccine candidate for the prevention of COVID-19 being developed by the Janssen Pharmaceutical Companies of Johnson & Johnson, continues to enroll and vaccinate study participants. ENSEMBLE is proceeding to enroll up to 60,000 participants worldwide.In addition to the single-dose regimen ENSEMBLE study, Janssen has now initiated the two-dose regimen ENSEMBLE 2 trial. ENSEMBLE 2 is a complementary, planned, pivotal, large-scale, multi-country Phase 3 trial that will study the safety and efficacy of a two-dose ...
Source: Johnson and Johnson - November 16, 2020 Category: Pharmaceuticals Tags: Our Company Source Type: news

Rural practices struggling to deliver 'urban-focused' PCN targets, NIHR report warns
GPs in rural areas are struggling to deliver primary care network (PCN) targets because national policy is built around 'leading light' networks in urban areas, a study has found. (Source: GP Online News)
Source: GP Online News - November 13, 2020 Category: Primary Care Tags: Primary care networks Source Type: news

New National Patient Recruitment Centres for late phase commercial clinical research
(NIHR Clinical Research Network Eastern) The National Institute for Health Research has launched five new Patient Recruitment Centres to enable more late phase commercial clinical research to be delivered within the NHS. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 12, 2020 Category: Infectious Diseases Source Type: news

People of Black and Asian ethnicity up to twice as likely to be infected with COVID-19 as those of White ethnicity
(National Institute for Health Research) People of Black ethnicity are twice as likely to be infected with COVID-19 compared to those of White ethnicity. People from Asian backgrounds are 1.5 times more likely to become infected with the virus compared to White individuals. Those of Asian ethnicities may be at higher risk of admission to an intensive therapy unit (ITU) and death. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 12, 2020 Category: Infectious Diseases Source Type: news

#8Investments to enable everyone, everywhere, to be physically active
Researchers from the University of Bristol and NIHR ARC West have contributed to the International Society for Physical Activity and Health (ISPAH) ‘ Eight Investments That Work for Physical Activity ‘ , released today [10 November]. (Source: University of Bristol news)
Source: University of Bristol news - November 10, 2020 Category: Universities & Medical Training Tags: Health, International, Research; Faculty of Health Sciences, Faculty of Health Sciences, Population Health Sciences, Faculty of Social Sciences and Law, Faculty of Social Sciences and Law, School for Policy Studies; Press Release Source Type: news