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Author interview: Suite of reviews on pressure ulcers
Pressure ulcers, also known as pressure sores or bed sores, are wounds to the skin and underlying tissue caused by prolonged pressure or rubbing. People who have mobility problems or who lie in bed for long periods are at risk of developing pressure ulcers.Cochrane Wounds has recently published a suite of reviews on this topic, lead author Chunhu Shi tells us about these reviews.How did this suite of reviews come about?The relative effectiveness of different types of beds and mattresses (support surfaces) for preventing pressure ulcers prevention came out as a “top uncertainty” in a priory setting exercise involving pa...
Source: Cochrane News and Events - May 13, 2021 Category: Information Technology Authors: Lydia Parsonson Source Type: news

Gene therapy offers potential cure to children born without an immune system
An experimental form of gene therapy developed by a team of researchers from UCLA and Great Ormond Street Hospital in London has successfully treated 48 of 50 children born with a rare and deadly inherited disorder that leaves them without an immune system.Severe combined immunodeficiency due to adenosine deaminase deficiency, or ADA-SCID, is caused by mutations in theADA gene that creates the enzyme adenosine deaminase, which is essential to a functioning immune system.For children with the condition, even day-to-day activities like going to school or playing with friends can lead to dangerous, life-threatening infections...
Source: UCLA Newsroom: Health Sciences - May 11, 2021 Category: Universities & Medical Training Source Type: news

Future-proofing mental health -- Experts set out research roadmap to prioritise key areas
(Taylor& Francis Group) In a commentary, backed by Professor Chris Whitty, Chief Medical Officer and co-lead of the National Institute for Health Research, experts are calling for targets for mental health in order to meet the healthcare challenges of the next decade. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 9, 2021 Category: International Medicine & Public Health Source Type: news

Exercise can help support recovery of patients with lasting COVID symptoms, study finds
(National Institute for Health Research) Patients with lasting symptoms of COVID-19 who completed a six week, supervised rehabilitation programme demonstrated significant improvements in exercise capacity, respiratory symptoms, fatigue and cognition. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - May 7, 2021 Category: Infectious Diseases Source Type: news

Effects of BNT162b2 mRNA vaccine on Covid-19 infection and hospitalisation among older people: matched case control study for England, NIHR
Receipt of the BNT162b2 mRNA vaccine is effective at reducing Covid-19 hospitalisations and infections. The nationwide vaccination of older adults in England with the BNT162b2 mRNA vaccine reduced the burden of Covid-19. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 5, 2021 Category: Consumer Health News Source Type: news

New prognostic review: Predicting relapse or recurrence of depression
In this author interview, lead authors Nick Meader and Andrew Moriarity tell us about thisrecently published Cochrane review, how they worked with a patient advisory group, and how they rose to the challenge of this being their first prognostic review, and the first of this type for Cochrane Common Mental Disorders.Nick Meader: According to the World Health Organization (WHO), depression is the leading cause of disability worldwide and, during the pandemic, depression symptoms have increased in many countries.We have effective treatments for depression (like antidepressants and cognitive behavioural therapy). So, a substan...
Source: Cochrane News and Events - May 5, 2021 Category: Information Technology Authors: Katie Abbotts Source Type: news

Bristol study to improve success of IVF treatment resumes
A major study into the factors affecting IVF treatment success, led by NIHR Bristol Biomedical Research Centre (BRC) researchers at the University of Bristol, is restarting after a year-long pause due to COVID-19. (Source: University of Bristol news)
Source: University of Bristol news - April 29, 2021 Category: Universities & Medical Training Tags: Health, International, Research; Faculty of Health Sciences, Faculty of Health Sciences, Bristol Medical School, Faculty of Health Sciences, Population Health Sciences, Institutes, Institutes, Bristol Population Health Science Institute; Press Release Source Type: news

NIHR Bristol BRC to benefit from internship programme to tackle underrepresentation of Black people in science
The National Institute for Health Research Bristol Biomedical Research Centre (NIHR Bristol BRC), a partnership between the University of Bristol and University Hospitals Bristol and Weston NHS Foundation Trust (UHBW), will host intern Angel Obierozie this summer as part of the Health Data Research UK (HDR UK) programme to tackle the underrepresentation of Black people in science. (Source: University of Bristol news)
Source: University of Bristol news - April 20, 2021 Category: Universities & Medical Training Tags: Research, Health; Faculty of Health Sciences, Faculty of Health Sciences, Bristol Medical School, Faculty of Health Sciences, Population Health Sciences, Faculty of Health Sciences, Translational Health Sciences; Press Release Source Type: news

Cochrane PaPaS seeks full-time Systematic Reviewer - remote
Closing date: 28 April 2021Location: remote (home-working)The Cochrane Pain, Palliative and Supportive Care (Cochrane PaPaS) Review Group is looking for an experienced Systematic Reviewer to undertake high quality, priority Cochrane systematic reviews for publication in the Cochrane Library.The focus of PaPaS is studies of interventions for acute pain, chronic pain, headache and migraine, palliative care for those with life-limiting disease or illness, and supportive care of patients and significant others living with serious illness.The candidate will work with a multidisciplinary team to undertake new priority reviews, o...
Source: Cochrane News and Events - April 19, 2021 Category: Information Technology Authors: Lydia Parsonson Source Type: news

Autism in the Somali community – myth-busting short films offer advice and top tips for parents
A series of five evidence-based short films and factsheets about autism for the Somali community have been launched by National Institute for Health Research (NIHR) funded researchers at the University of Bristol and community organisation Autism Independence. (Source: University of Bristol news)
Source: University of Bristol news - March 29, 2021 Category: Universities & Medical Training Tags: Health, Research; Faculty of Health Sciences, Bristol Medical School; Press Release Source Type: news

Homelessness and unstable housing are associated with increased HIV and HCV risk among people who inject drugs
Homelessness and unstable housing are associated with a substantial increase in HIV and hepatitis C virus (HCV) acquisition risk among people who inject drugs, according to research led by the NIHR Health Protection Research Unit in Behavioural Science and Evaluation at the University of Bristol. (Source: University of Bristol news)
Source: University of Bristol news - March 26, 2021 Category: Universities & Medical Training Tags: Health, Research; Faculty of Health Sciences, Bristol Medical School, Faculty of Health Sciences; Press Release Source Type: news

Cochrane Dementia and Cognitive Improvement Group dispels myths on podcast
Latest episode of the DementiaResearcher podcastchats about the work of Cochrane, how we support evidence-informed decision making in healthcare, our work on undertaking systematic reviews, and how you could become involved.TheCochrane Dementia and Cognitive Improvement Group create reviews and methods guidance on all aspects of dementia, delirium and other cognitive disorders. Recent outputs have included a focus on diagnosis of dementia,which have been curated in to a Cochrane Library Special Collection, and reviews on prognosis and complex interventions.The group Coordinating Editors are Dr Jenny McCleery and ...
Source: Cochrane News and Events - March 26, 2021 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Volunteers needed for study looking into whether COVID-19 and flu vaccines can be administered at the same time
Researchers at the Bristol Trials Centre (CTEU) at the University of Bristol and University Hospitals Bristol and Weston NHS Foundation Trust (UHBW) are leading a new study which could set the foundations for how booster COVID-19 vaccinations are delivered in the future. The study, supported by the National Institute for Health Research (NIHR), will determine whether booster COVID-19 vaccines should be given at the same time as flu vaccines. (Source: University of Bristol news)
Source: University of Bristol news - March 26, 2021 Category: Universities & Medical Training Tags: Research, Health; Faculty of Health Sciences, Bristol Medical School, Faculty of Health Sciences; Press Release Source Type: news

Modelling of hypothetical SARS-CoV-2 point-of-care tests on admission to hospital from A & E: rapid cost-effectiveness analysis, NIHR
Thirty-two strategies involving different hypothetical SARS-CoV-2 tests were modelled as were recently published desirable and acceptable target product profiles for SARS-CoV-2 point-of-care tests. Given the heterogeneity of hospitals, no blanket solution can be provided. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 26, 2021 Category: Consumer Health News Source Type: news

Patients should receive COVID-19 vaccine before surgery to reduce risk of death
(University of Birmingham) Patients waiting for elective surgery should get COVID-19 vaccines ahead of the general population - potentially helping to avoid thousands of post-operative deaths linked to the virus, according to a new study funded by the NIHR. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 24, 2021 Category: Infectious Diseases Source Type: news