Trialing treatments for Long Covid, and a new organelle appears on the scene
]Researchers are testing HIV drugs and monoclonal antibodies against long-lasting COVID-19, and what it takes to turn a symbiotic friend into an organelle First up on the show this week, clinical trials of new and old treatments for Long Covid. Producer Meagan Cantwell is joined by Staff Writer Jennifer Couzin-Frankel and some of her sources to discuss the difficulties of studying and treating this debilitating disease. People in this segment:·      Michael Peluso·      Sara Cherry·      Shelley Hayden Next: Move over mitochondria, a new organelle called the nitroplast is here. Host Sarah Crespi tal...
Source: Science Magazine Podcast - April 11, 2024 Category: Science Authors: Science Magazine Source Type: podcasts

Why are we nice? Altruism's origins are put to the test
In this episode:00:45 Why are humans so helpful?Humans are notable for their cooperation and display far more altruistic behaviour than other animals, but exactly why this behaviour evolved has been a puzzle. But in a new paper, the two leading theories have been put the test with a model and a real-life experiment. They find that actually neither theory on its own leads to cooperation but a combination is required for humans to help one another.Research article: Efferson et al.News and Views: Why reciprocity is common in humans but rare in other animals10:55 Research HighlightsThe discovery of an ancient stone wall hidden...
Source: Nature Podcast - February 21, 2024 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 1049: Long COVID's book of homeostatic cats
TWiV explains how immune profiling was used to identify distinguishing features of Long COVID, and how a co-opted feline endogenous retroviral envelope promotes cell survival by controlling copper transport and homeostasis in cats. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Spike shirts at vaccinated.us (promo code Microbetv) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) Features of Long COVID (Nature) ERV ...
Source: This Week in Virology - MP3 Edition - October 1, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1029: David Tuller on Long COVID and ME/CFS
David Tuller returns to TWiV to provide an update on ME/CFS, the PACE trial, developments related to the NICE guidelines, and how similar practices and ideologies are being applied to long COVID. Host: Vincent Racaniello Guest: David Tuller Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server David Tuller at virology blog CFS, a long tangled tale (virology blog) Request for Correction of Prevalence Rates Cited in FND Paper (virology blog) Estimates of long COVID prevalence (virology blog) Timestamps by Jolene. Thanks! Intro musi...
Source: This Week in Virology - MP3 Edition - July 27, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 750: To err is viral
The TWiVmeisters discuss how copy-back defective viral genomes might modulate the clinical outcome of respiratory syncytial virus infection, and detection of antibodies to henipa- and filo-like viruses in Trinidad bats. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Vaccine education town halls (ASV) RSV cpDVG may influence clinical outcome (Nat Micro) Henipa- and filo-like viruses in Trinidad bats (J Inf Dis) Nice image of cpDVG generation Letters read on TWiV 750 Timesta...
Source: This Week in Virology - MP3 Edition - May 2, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

The Deep Breath talking wellbeing evidence round-up of the year.
In this end-of-year podcast from Deep Breath In, we're bringing you a light hearted look back at 2020, and trying to remember some of the non-covid-19 medicine that has crossed our desks. This festive quiz features the deep breath in gang, as well as Cat Chatfield from the Wellbeing podcast, and Helen Macdonald from our Talk Evidence podcasts. Reading list; Thyroid disease assessment and management: summary of NICE guidance https://www.bmj.com/content/368/bmj.m41 Thyroid hormones treatment for subclinical hypothyroidism: a clinical practice guideline https://www.bmj.com/content/365/bmj.l2006 Judd Brewer's advice for c...
Source: The BMJ Podcast - January 1, 2021 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts

The Deep Breath talking wellbeing evidence round-up of the year.
In this end-of-year podcast from Deep Breath In, we're bringing you a light hearted look back at 2020, and trying to remember some of the non-covid-19 medicine that has crossed our desks. This festive quiz features the deep breath in gang, as well as Cat Chatfield from the Wellbeing podcast, and Helen Macdonald from our Talk Evidence podcasts. Reading list; Thyroid disease assessment and management: summary of NICE guidance https://www.bmj.com/content/368/bmj.m41 Thyroid hormones treatment for subclinical hypothyroidism: a clinical practice guideline https://www.bmj.com/content/365/bmj.l2006 Judd Brewer's advice for co...
Source: The BMJ Podcast - January 1, 2021 Category: General Medicine Authors: BMJ Group Source Type: podcasts

TWiV 680: Long-term COVID and ME/CFS
Mady, Fiona, and David join TWiV to discuss patients with long-term COVID and similarities and differences with ME/CFS. Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker Guests: Mady Hornig, Fiona Lowenstein, and David Tuller Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Body Politic Survivor Corps Long-haulers redefining COVID-19 (Ed Yong) I’m 26. Coronavirus sent me to the hospital (Fiona Lowenstein) We need to talk about what coronavirus recoveries look like (Fiona Lowenstein) COVID-19 long term disability (Mady Hornig, David Tuller) At 12, sheâ€...
Source: This Week in Virology - MP3 Edition - November 12, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss
For the next few months Talk Evidence is going to focus on the new corona virus pandemic. There is an enormous amount of uncertainty about the disease, what the symptoms are, fatality rate, treatment options, things we shouldn't be doing. We're going to try to get away from the headlines and talk about what we need to know - to hopefully give you some insight into these issues. This week: (2.24) - Hydroxychloroquinine/chloroquinine - Robin Ferner, honorary professor of clinical pharmacology at the University of Birmingham explains why is it a potential therapeutic for covid-19, and why is it being hyped. (12.45) - W...
Source: The BMJ Podcast - April 13, 2020 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts

Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss
For the next few months Talk Evidence is going to focus on the new corona virus pandemic. There is an enormous amount of uncertainty about the disease, what the symptoms are, fatality rate, treatment options, things we shouldn't be doing. We're going to try to get away from the headlines and talk about what we need to know - to hopefully give you some insight into these issues. This week: (2.24) - Hydroxychloroquinine/chloroquinine - Robin Ferner, honorary professor of clinical pharmacology at the University of Birmingham explains why is it a potential therapeutic for covid-19, and why is it being hyped. (12.45) - W...
Source: The BMJ Podcast - April 13, 2020 Category: General Medicine Authors: BMJ Group Source Type: podcasts

Sustainable health
The UK has just seen it ’s hottest July on record, including the highest ever temperature recorded. With climate change in the forefront of our minds, it’s timely that we have two editorials on the sustainability and health. Michael Depledge, emeritus professor of environment and human health at University of Exeter Medical School, and author of the editorial Time and Tide, explains how closely the oceans and seas are linked to human health. Also Gillian Leng, deputy chief executive and director of health and social care at NICE has ideas about what the NHS can do to become more sustainable, and how we could e valuat...
Source: The BMJ Podcast - August 2, 2019 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts

Sustainable health
The UK has just seen it’s hottest July on record, including the highest ever temperature recorded. With climate change in the forefront of our minds, it’s timely that we have two editorials on the sustainability and health. Michael Depledge, emeritus professor of environment and human health at University of Exeter Medical School, and author of the editorial Time and Tide, explains how closely the oceans and seas are linked to human health. Also Gillian Leng, deputy chief executive and director of health and social care at NICE has ideas about what the NHS can do to become more sustainable, and how we could evaluate ...
Source: The BMJ Podcast - August 2, 2019 Category: General Medicine Authors: BMJ Group Source Type: podcasts

What's it like to live with a vaginal mesh?
What can we learn from the shameful story of vaginal mesh? That thousands of women have been irreversibly harmed; that implants were approved on the flimsiest of evidence; that surgeons weren ’t adequately trained and patients weren’t properly informed; that the dash for mesh, fuelled by its manufacturers, stopped the development of alternatives; that surgeons failed to set up mesh registries that would have identified complications sooner; and that the National Institute for Health and Clinical Excellence and the UK regulators let them off the hook. The BMJ has a published an investigation into vaginal mesh, which ch...
Source: The BMJ Podcast - October 12, 2018 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts