HDL-Raising Drugs Probably Won't Work, But This Might
A new study offers important new insights into the protective role of HDL cholesterol (the "good" cholesterol) against cardiovascular disease. Earlier studies with drugs that increase HDL levels, including niacin and CETP inhibitors, have not shown benefit. The new study suggests that simply increasing HDL levels isn't the way to go. Instead, cholesterol efflux, the ability of HDL to remove cholesterol from cells, part of the process called reverse cholesterol transport, appears to be the key. The results were presented today by Anand Rohatgi at the American Heart Association meeting in Chicago and...
Source: Forbes.com Healthcare News - November 18, 2014 Category: Pharmaceuticals Authors: Larry Husten Source Type: news
Niacin With Statins? No Dice.Niacin With Statins? No Dice.
Wilbert Aronow comments on the trial that slammed the door on niacin for lipid-lowering. Faculty of 1000 (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 19, 2014 Category: Consumer Health News Tags: Family Medicine/Primary Care Commentary Source Type: news
Niacin can boost 'good' cholesterol
(Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - August 12, 2014 Category: Consumer Health News Source Type: news
HDL-Raising Drugs: No Value in the Statin Era?HDL-Raising Drugs: No Value in the Statin Era?
In the era of widespread statin use, investigators say studies testing fibrates, niacin, and CETP inhibitors do not support raising HDL pharmacologically to reduce clinical outcomes. Heartwire (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - July 24, 2014 Category: Cardiology Tags: Cardiology News Source Type: news
Niacin, Heart Disease And The Fallacy That All Older Drugs Are Safe And Effective
The bottom line is that no drug is perfect; all have side-effects. There is no guarantee that either the age or newness of a drug will confer better safety or efficacy. One thing you can be certain of, however, is that drugs approved today have been studied in greater depth than ever before. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - July 24, 2014 Category: Pharmaceuticals Authors: John LaMattina Source Type: news
Five Lessons From the Niacin FailureFive Lessons From the Niacin Failure
Dr Mandrola laments the failure of yet another surrogate marker. What should cardiologists learn from negative trials like this? theheart.org on Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - July 21, 2014 Category: Cardiology Tags: Cardiology Expert Column Source Type: news
Stressed women gain more pounds
Five studies you may have missed: niacin and your heart, stressed women get fat, a better HPV test, and why sitting may not be so bad if you do this. (Source: CNN.com - Health)
Source: CNN.com - Health - July 19, 2014 Category: Consumer Health News Source Type: news
PodMed: A Medical News Roundup From Johns Hopkins (with audio)
(MedPage Today) -- This week's topics include stroke and risk, pill color and compliance, telecare for pain management, and niacin for prevention of heart disease. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - July 18, 2014 Category: Cardiology Source Type: news
Stress = fat and fitter sitting, in 5 studies you may have missed
Five studies you may have missed: niacin and your heart, stressed women get fat, a better HPV test, and why sitting may not be so bad if you do this. (Source: CNN.com - Health)
Source: CNN.com - Health - July 18, 2014 Category: Consumer Health News Source Type: news
HPS2-THRIVE: Game (Mostly) Over for Niacin (CME/CE)
(MedPage Today) -- Publication of landmark trial results affirmed no benefit and worrisome adverse events from adding extended-release niacin to statin therapy, but many physicians weren't ready to concede failure of the purported HDL mechanism. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - July 18, 2014 Category: Cardiology Source Type: news
Heart drug niacin may pose serious health risks
Research has found a troubling rise in deaths among people who use popular drug to manage cholesterol (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - July 17, 2014 Category: Consumer Health News Source Type: news
Morning Break: The B.O. Talk, No Love for Niacin
(MedPage Today) -- Health news and commentary from around the Web, gathered by the MedPage Today staff. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - July 17, 2014 Category: Primary Care Source Type: news
HPS2-THRIVE: As Niacin Fails, HDL's Role Is Debated AnewHPS2-THRIVE: As Niacin Fails, HDL's Role Is Debated Anew
Given the negative results from AIM-HIGH and HPS2-THRIVE, as well as other negative studies, the cardiovascular research community is grappling with the future of managing HDL-cholesterol levels to reduce clinical risk. Heartwire (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - July 17, 2014 Category: Cardiology Tags: Cardiology News Source Type: news
Niacin Doesn't Reduce Heart Problems, May Create Some, Research Finds
Title: Niacin Doesn't Reduce Heart Problems, May Create Some, Research FindsCategory: Health NewsCreated: 7/17/2014 12:36:00 AMLast Editorial Review: 7/17/2014 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - July 17, 2014 Category: Cardiology Source Type: news
Niacin Doesn't Reduce Heart Problems, May Create Some, Research Finds
Talk with your doctor about whether or not you should keep taking it, expert advises (Source: WebMD Health)
Source: WebMD Health - July 17, 2014 Category: Consumer Health News Source Type: news
