niacin and lovastatin, Advicor
Title: niacin and lovastatin, AdvicorCategory: MedicationsCreated: 10/13/2004 12:00:00 AMLast Editorial Review: 8/29/2019 12:00:00 AM (Source: MedicineNet Cholesterol General)
Source: MedicineNet Cholesterol General - August 29, 2019 Category: Cardiology Source Type: news
Prescription omega-3s can help some heart patients
For people with very high triglycerides, doctors generally recommend exercise and dietary changes, and if that doesn't work, statins, fibrates or niacin. But a new advisory from the American Heart Association says that prescription omega-3 fatty acids can help reduce very high trigylceride levels by 20 to 30%, and the medications can be used safely in conjunction with statins. (Source: CNN.com - Health)
Source: CNN.com - Health - August 19, 2019 Category: Consumer Health News Source Type: news
Lipitor (atorvastatin) vs. Niacin (nicotinic acid, vitamin B3)
Title: Lipitor (atorvastatin) vs. Niacin (nicotinic acid, vitamin B3)Category: MedicationsCreated: 5/17/2019 12:00:00 AMLast Editorial Review: 5/17/2019 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - May 17, 2019 Category: Cardiology Source Type: news
May 3 2019 This Week in Cardiology May 3 2019 This Week in Cardiology
Bike commuting and obesity, CMR for NSTEMI, Niacin in secondary prevention, cardiologists ’ pay, and end-of-life conversations are in this week ’ s podcast.theheart.org on Medscape (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 3, 2019 Category: Consumer Health News Tags: Cardiology Commentary Source Type: news
The Shaky Role for Niacin in Secondary Prevention The Shaky Role for Niacin in Secondary Prevention
A meta-analysis suggests evidence of clinical benefit is insufficient and not generalizable to contemporary practice, but others say some subgroups may still derive benefit.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - April 29, 2019 Category: Cardiology Tags: Cardiology News Source Type: news
niacin (Niacor, Niaspan)
Title: niacin (Niacor, Niaspan)Category: MedicationsCreated: 10/13/2004 12:00:00 AMLast Editorial Review: 3/21/2019 12:00:00 AM (Source: MedicineNet Cholesterol General)
Source: MedicineNet Cholesterol General - March 21, 2019 Category: Cardiology Source Type: news
ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation
The earliest intracellular signals that occur after T cell activation are local, subsecond Ca2+ microdomains. Here, we identified a Ca2+ entry component involved in Ca2+ microdomain formation in both unstimulated and stimulated T cells. In unstimulated T cells, spontaneously generated small Ca2+ microdomains required ORAI1, STIM1, and STIM2. Super-resolution microscopy of unstimulated T cells identified a circular subplasmalemmal region with a diameter of about 300 nm with preformed patches of colocalized ORAI1, ryanodine receptors (RYRs), and STIM1. Preformed complexes of STIM1 and ORAI1 in unstimulated cells were confirm...
Source: Signal Transduction Knowledge Environment - December 18, 2018 Category: Science Authors: Diercks, B.-P., Werner, R., Weidemüller, P., Czarniak, F., Hernandez, L., Lehmann, C., Rosche, A., Krüger, A., Kaufmann, U., Vaeth, M., Failla, A. V., Zobiak, B., Kandil, F. I., Schetelig, D., Ruthenbeck, A., Meier, C., Lodygin, D., Flu&#x Tags: STKE Research Articles Source Type: news
Hippocampal mGluR1-dependent long-term potentiation requires NAADP-mediated acidic store Ca2+ signaling
Acidic organelles, such as endosomes and lysosomes, store Ca2+ that is released in response to intracellular increases in the second messenger nicotinic acid adenine dinucleotide phosphate (NAADP). In neurons, NAADP and Ca2+ signaling contribute to synaptic plasticity, a process of activity-dependent long-term potentiation (LTP) [or, alternatively, long-term depression (LTD)] of synaptic strength and neuronal transmission that is critical for neuronal function and memory formation. We explored the function of and mechanisms regulating acidic Ca2+ store signaling in murine hippocampal neurons. We found that metabotropic glu...
Source: Signal Transduction Knowledge Environment - November 27, 2018 Category: Science Authors: Foster, W. J., Taylor, H. B. C., Padamsey, Z., Jeans, A. F., Galione, A., Emptage, N. J. Tags: STKE Research Articles Source Type: news
Niacin to boost your HDL, 'good,' cholesterol
Niacin is a B vitamin that may raise your HDL, 'good,' cholesterol. Find out if you should take niacin to boost your HDL cholesterol. (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - May 16, 2018 Category: Consumer Health News Source Type: news
Preventing Cardiovascular, Cerebrovascular Events With Niacin Preventing Cardiovascular, Cerebrovascular Events With Niacin
Should niacin be used either as monotherapy or in addition to statin therapy for primary or secondary prevention of cardiovascular or cerebrovascular events?American Family Physician (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 3, 2018 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news
mTORC1 controls lysosomal Ca2+ release through the two-pore channel TPC2
Two-pore segment channel 2 (TPC2) is a ubiquitously expressed, lysosomally targeted ion channel that aids in terminating autophagy and is inhibited upon its association with mechanistic target of rapamycin (mTOR). It is controversial whether TPC2 mediates lysosomal Ca2+ release or selectively conducts Na+ and whether the binding of nicotinic acid adenine dinucleotide phosphate (NAADP) or phosphatidylinositol 3,5-bisphosphate [PI(3,5)P2] is required for the activity of this ion channel. We show that TPC2 is required for intracellular Ca2+ signaling in response to NAADP or to mTOR inhibition by rapamycin. In pulmonary arteri...
Source: Signal Transduction Knowledge Environment - April 10, 2018 Category: Science Authors: Ogunbayo, O. A., Duan, J., Xiong, J., Wang, Q., Feng, X., Ma, J., Zhu, M. X., Evans, A. M. Tags: STKE Research Articles Source Type: news
A Heart Risk Factor Even Doctors Know Little About
Up to one in five Americans have high levels of lipoprotein(a) in their blood, putting them at risk of heart attacks and strokes. (Source: NYT Health)
Source: NYT Health - January 9, 2018 Category: Consumer Health News Authors: ANAHAD O ’ CONNOR Tags: Tests (Medical) Heart Cholesterol Exercise Weight Stroke Lipoproteins Diet and Nutrition Drugs (Pharmaceuticals) Niacin Doctors Source Type: news
U.S. drugmaker raises price of vitamins by more than 800%
Cost of a bottle of 100 tablets of Avondale ’s Niacor increased from $32.46 to $295. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - December 11, 2017 Category: Biotechnology Authors: By David Crow in New York Source Type: news
U.S. drugmaker raises price of vitamins by more than 800%
Cost of a bottle of 100 tablets of Avondale ’s Niacor increased from $32.46 to $295. (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - December 11, 2017 Category: American Health Authors: By David Crow in New York Source Type: news
US drugmaker raises price of vitamins by more than 800%
Cost of a bottle of 100 tablets of Avondale’s Niacor increased from $32.46 to $295 (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - December 10, 2017 Category: Pharmaceuticals Source Type: news
