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For biologists studying tiny worms, new technologies make big improvements
Two new technologies are helping scientists understand new aspects of organ and nervous system development in C. elegans. One allows them to image worms developing in a natural environment, while the other makes it possible to track single neurons as the worms grow. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - March 16, 2017 Category: Biomedical Science Authors: Katie Fenz Tags: Science News biotechnology c. elegans development Eric Siggia Laboratory of Developmental Genetics Laboratory of Theoretical Condensed Matter Physics Shai Shaham Source Type: news

Early intervention with new treatment provides durable control of HIV-like virus in monkeys
Researchers have found that a new approach to HIV treatment can suppress an HIV-like virus for an extended period in monkeys. The therapy employs antibodies and takes advantage of the immune system’s natural defenses. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - March 13, 2017 Category: Biomedical Science Authors: Katie Fenz Tags: Science News 10-1074 3BNC117 broadly neutralizing antibodies controllers HIV immunotherapy Laboratory of Molecular Immunology Michel C. Nussenzweig Michel Nussenzweig Source Type: news

Study tests the “three-hit” theory of autism
Could a genetic predisposition to autism together with early stress have a more detrimental effect on boys than on girls? In experiments with mice, researchers found evidence that three factors—genes, environment, and sex—work together to produce problems with social interaction, a hallmark of autism. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - March 7, 2017 Category: Biomedical Science Authors: Wynne Perry Tags: Science News Source Type: news

A new way to reset gene expression in cancer cells shows promise for leukemia treatment
Scientists have discovered a potential new target for the treatment of leukemia that potentially could augment the activity of BET inhibitors, drugs currently in clinical trials. These therapies act on histones, DNA’s packaging proteins, to reset gene regulatory programs that go awry in cancer. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - March 6, 2017 Category: Biomedical Science Authors: Tashian Myers Tags: Science News C. David Allis cancer chemical and structural biology ENL epigenetics epigenome genetics and genomics histones Leukemia Liling Wan molecular and cell biology Source Type: news

In the News – NPR – Brivanlou
Embryo Experiments Reveal Earliest Human Development, But Stir Ethical Debate   “‘The amazing thing is that it’s doing its thing without any information from mom,’ Brivanlou says. ‘It just has all the information already in it. That was mind-blowing to … More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - March 2, 2017 Category: Biomedical Science Authors: Katie Fenz Tags: In the News Ali Brivanlou embryo development human development infertility Laboratory of Stem Cell Biology and Molecular Embryology self-organization Source Type: news

Raphael Cohn wins 2017 Weintraub Graduate Student Award
Cohn, a member of Vanessa Ruta’s Laboratory of Neurophysiology and Behavior, is one of 13 recipients of this prestigious prize, which is given to graduate students at or near the completion of their studies in the biological sciences. Winners are selected for the originality and significance of their thesis research. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - March 1, 2017 Category: Biomedical Science Authors: Tashian Myers Tags: Awards and Honors Raphael Cohn Vanessa Ruta Weintraub Award Weintraub Graduate Student Award Source Type: news

New structural studies reveal workings of a molecular pump that ejects cancer drugs
Sometimes cells spit out things we don’t want them to—like medications. Researchers have determined the three-dimensional structure of a tiny pump that expels, among other things, chemotherapy agents. This new knowledge could lead to the design of more effective drugs. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - February 24, 2017 Category: Biomedical Science Authors: Wynne Perry Tags: Science News ABC transporters cancer biology chemical and structural biology drug resistance Jue Chen Laboratory of Membrane Biology and Biophysics molecular pumps MRP1 Zachary Johnson Source Type: news

New research explains why a common bacterium can produce severe illness
How can the same infection result in dramatically different levels of illness in two different people? A new study identifies two conditions—a genetic immunodeficiency and delayed acquired immunity—that explain why a patient developed a life-threatening disease in response to a common strain of bacterium. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - February 23, 2017 Category: Biomedical Science Authors: Katie Fenz Tags: Science News case study immune system Jean-Laurent Casanova St. Giles Laboratory of Human Genetics of Infectious Diseases Staphylococcus aureus Source Type: news

Oceanographer and explorer Sylvia Earle will receive the 2017 Lewis Thomas Prize
Oceanographer and explorer Sylvia Earle has been named the recipient of Rockefeller’s prestigious science writing prize. The award recognizes Earle’s body of work, which includes memoirs, atlases, and children’s books, as well as advocacy for global marine conservation. Earle will be honored at an award ceremony on March 6. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - February 22, 2017 Category: Biomedical Science Authors: Alexandra MacWade Tags: Awards and Honors Jesse Ausubel Jesse H. Ausubel Lewis Thomas Prize Lewis Thomas Prize for Writing about Science Sylvia Earle Source Type: news

Jeffrey V. Ravetch receives 2017 Ross Prize in Molecular Medicine
Ravetch, who studies the role of antibodies in the immune system, has won the 2017 Ross Prize in Molecular Medicine. Given by The Feinstein Institute for Medical Research and its journal Molecular Medicine, the award recognizes scientists who have made a significant impact on the understanding of human disease pathogenesis. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - February 21, 2017 Category: Biomedical Science Authors: Alexandra MacWade Tags: Awards and Honors Jeffrey Ravetch Jeffrey V. Ravetch Laboratory of Molecular Genetics and Immunology Ross Prize Ross Prize in Molecular Medicine Source Type: news

Crowdsourcing effort helps researchers predict how a molecule will smell
While it’s possible to anticipate the color of light or the pitch of sound, odor defies prediction. New research has taken an important step toward decoding smell, by linking a scent back to a molecule’s chemistry. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - February 20, 2017 Category: Biomedical Science Authors: Wynne Perry Tags: Science News Source Type: news

Mouse studies offer new insights about cocaine ’s effect on the brain
Researchers have determined how a specific protein regulates the brain’s response to cocaine. Their findings provide fresh insights into the neurobiology of addiction, and could lead to the development of better interventions and treatments. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - February 15, 2017 Category: Biomedical Science Authors: Tashian Myers Tags: Science News addiction cocaine dopamine Laboratory of Molecular and Cellular Neuroscience molecular and cell biology Paul Greengard WAVE1 Yong Kim Source Type: news

Newly discovered beetle species named after Rockefeller ’s Daniel Kronauer
A former Rockefeller postdoctoral associate has named a new species of beetle Nymphister kronaueri, after his mentor, Daniel Kronauer. Discovered in the Costa Rican rainforest, the beetle anchors itself tightly to backside of nomadic ants, hitchhiking a ride to new nesting sites. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - February 13, 2017 Category: Biomedical Science Authors: Katie Fenz Tags: Science News ants beetles Daniel Kronauer nomenclature Nymphister kronaueri Source Type: news

Scientists discover an unexpected influence on dividing stem cells ’ fate
When it divides, a stem cell has a choice: produce more stem cells or turn into the specific types of cells that compose skin, muscle, brain, or other tissue. New experiments in skin show this decision can be altered if tiny organs within cells aren’t positioned and divvied up properly. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - February 10, 2017 Category: Biomedical Science Authors: Wynne Perry Tags: Science News Amma Asare cell division Elaine Fuchs Laboratory of Mammalian Cell Biology mitosis organelle inheritance peroxisomes pex11b stem cells Source Type: news

Howard C. Hang receives 2017 Eli Lilly Award in Biological Chemistry
Hang, who develops chemical tools to study microbe–host interactions, has won the 2017 Eli Lilly Award in Biological Chemistry. The prize, given by the American Chemical Society, recognizes outstanding research in biological chemistry of unusual merit and independence of thought and originality. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - February 7, 2017 Category: Biomedical Science Authors: Tashian Myers Tags: Awards and Honors Eli Lilly Award Eli Lilly Award in Biological Chemistry Howard C. Hang Howard Hang Laboratory of Chemical Biology and Microbial Pathogenesis Source Type: news