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Scientists engineer human-germ hybrid molecules to attack drug-resistant bacteria
Taking a cue from viruses that infect and kill bacteria, the researchers engineered molecules capable of targeting the bugs in a way the human immune system cannot—an approach that could be particularly valuable against antibiotic-resistant bacteria. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - April 17, 2017 Category: Biomedical Science Authors: Tashian Myers Tags: Science News antibiotic resistance Assaf Raz immunology Laboratory of Bacterial Pathogenesis and Immunology lysibodies lysins microbiology Vincent A. Fischetti Virology Source Type: news

Viral fossils reveal how our ancestors may have eliminated an ancient infection
Some viruses can insert their genetic material into the genome of their host, creating a genetic fossil record. Researchers have uncovered how our ancestors may have wiped out one such virus around 11 million years ago. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - April 13, 2017 Category: Biomedical Science Authors: Katie Fenz Tags: Science News ancient infections Laboratory of Retrovirology Paul Bieniasz retroviruses viral fossils Source Type: news

Shooting the messenger: how one protein allows germ cells to develop
Researchers have identified a molecule that guides the formation of eggs and sperm by preventing a host of factors related to cell death and inflammation from killing the precursors to these cells. Their findings reveal new knowledge about how a mutation in this molecule leads to male sterility. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - April 13, 2017 Category: Biomedical Science Authors: Katie Fenz Tags: Science News germ cells Laboratory of RNA Molecular Biology RNA binding protein stem cells sterility Thomas Tuschl Source Type: news

Researchers track fish migration by testing DNA in seawater
For the first time, researchers have successfully recorded fish migration by conducting DNA tests on water samples. Using this method to estimate the abundance and distribution of fish species could help scientists more easily understand the impact certain environmental factors are having on local fish populations. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - April 12, 2017 Category: Biomedical Science Authors: Katie Fenz Tags: Science News eDNA fish migration Jesse Ausubel Mark Stoeckle Program for the Human Environment Source Type: news

Scientists discover how crucial DNA sequences endure
The centromere region of chromosomes retains the same DNA from one generation to the next. Scientists have gained new insights into how it avoids being scrambled in normal cells, and how it becomes unstable in cancer. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - April 10, 2017 Category: Biomedical Science Authors: Katie Fenz Tags: Science News cancer centromere DNA recombination Hironori Funabiki Laboratory of Chromosome and Cell Biology Source Type: news

Rockefeller tops ranking of 1,300 universities in measures of scientific impact and productivity
Released by the European Commission–funded U-Multirank, the survey placed Rockefeller first in categories related to scientific impact and research productivity. The results incorporate data on more than 1,300 institutions in over 90 countries. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - April 10, 2017 Category: Biomedical Science Authors: Tashian Myers Tags: Science News U-Multirank Source Type: news

In the News – NBC News – Young
This Night Owl Gene Mutation Turns People Into Sleep Martians “‘It’s as if these people have perpetual jet lag, moving eastward every day,’ said Michael Young, who oversaw the study. ‘In the morning, they’re not ready for the next day … More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - April 7, 2017 Category: Biomedical Science Authors: Katie Fenz Tags: In the News genetics Michael W. Young sleep Source Type: news

Rockefeller president Richard P. Lifton releases statement on proposed federal budget cuts to science
Responding to a White House budget proposal that calls for an 18 percent decrease in funding for the National Institutes of Health, Rockefeller President Richard P. Lifton today released a statement outlining the detrimental impact such cuts would have on health, national security, and the economy. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - April 6, 2017 Category: Biomedical Science Authors: Zach Veilleux Tags: Campus News Source Type: news

Study identifies “night owl” gene variant
Scientists have discovered a common mutation that might explain why some people have trouble going to sleep at night and getting up early. The gene alteration slows the internal biological clock that regulates our sleeping patterns. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - April 6, 2017 Category: Biomedical Science Authors: Tashian Myers Tags: Science News Alina Patke circadian clock circadian rhythm CRY1 DSPD insomnia Laboratory of Genetics Michael W. Young molecular and cell biology sleep Source Type: news

For microbes fighting viruses, a fast response means a better defense
Researchers have found that the bacterial immune system targets an invading virus as soon as it enters the cell. This discovery answers a long-standing question about how microbes defend themselves. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - March 29, 2017 Category: Biomedical Science Authors: Wynne Perry Tags: Science News CRISPR CRISPR-Cas9 immunology Joshua W. Modell Laboratory of Bacteriology Luciano Marraffini microbiology spacer acquisition Virology Source Type: news

Bridge Medicines appoints William J. Polvino as Chief Executive Officer
As Chief Executive Officer of the newly formed drug discovery company, founded by Rockefeller University and its two neighboring institutions, Polvino will be responsible for building a portfolio of early-stage drug discovery projects and advancing each program from animal proof of principle to clinical trials. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - March 27, 2017 Category: Biomedical Science Authors: Katie Fenz Tags: Campus News Bridge Medicines drug discovery Tri-I TDI William J. Polvino Source Type: news

New study resolves the structure of the human protein that causes cystic fibrosis
In order to better understand how genetic mutations give rise to cystic fibrosis, researchers need to map the protein responsible for the disorder. The new structure has led to new insights on how this molecular channel functions. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - March 23, 2017 Category: Biomedical Science Authors: Wynne Perry Tags: Science News CFTR cystic fibrosis David C. Gadsby Jue Chen Laboratory of Cardiac and Membrane Physiology Laboratory of Membrane Biology and Biophysics structural and chemical biology Source Type: news

Changes in the vascular system may trigger Alzheimer ’s disease
In some people whose cognitive functions are weakened due to Alzheimer’s, the disease can be traced back to changes in the brain’s blood vasculature. Scientists have found that a protein involved in blood clotting and inflammation might offer a potential path to new drugs. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - March 21, 2017 Category: Biomedical Science Authors: Tashian Myers Tags: Science News Alzheimer’s disease beta-amyloid neuroscience and behavior patricia and john rosenwald laboratory of neurobiology and genetics Sidney Strickland Zu-Lin Chen Source Type: news

In the News – Wall Street Journal – Brivanlou
Researchers Seek Guidelines for Embryo-Like Entities Created in Labs   “Some researchers say the concern is premature. Scientists in the lab of Ali Brivanlou at the Rockefeller University in 2014 published work describing how they reprogrammed cells taken from human … More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - March 21, 2017 Category: Biomedical Science Authors: Katie Fenz Tags: In the News 14-day rule Ali Brivanlou bioethics embryo development Source Type: news

David Rockefeller, university benefactor for 76 years, dies at 101
The entire Rockefeller University community deeply mourns the loss of David Rockefeller, our beloved friend and benefactor, Honorary Chairman, and Life Trustee. During its long and storied history, no single individual had a more profound influence on the University than David. His inspired leadership, extraordinary vision, and immense generosity have been essential factors in the University’s success. His values—especially his unequivocal commitment to excellence—shaped the University and made it the powerhouse of biomedical discovery it is today. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - March 20, 2017 Category: Biomedical Science Authors: Zach Veilleux Tags: Campus News Source Type: news