Some infants predisposed to epidermal barrier breakdown, atopic dermatitis
Neonates with the highest transepidermal water loss at birth, likely mediated through an impaired epidermal barrier, show significantly elevated chymotrypsinlike protease activity and reduced levels of filaggrin-derived natural moisturizing factors, which may predispose them to the development of... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 11, 2016 Category: Dermatology Source Type: news
Colombia reports first Zika deaths, all in medically compromised patients
AMSTERDAM – Five people with confirmed Zika virus infections have died in Colombia, and all had medical comorbidities, including leukemia, diabetes, sickle cell anemia, and hypertension.
All of the deaths occurred last October in northern and central Colombia, Dr. Alfonso Rodriguez-Morales said at... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 10, 2016 Category: Dermatology Source Type: news
Guidelines highlight revolution in advanced melanoma therapies
HOLLYWOOD, FLA. –The remarkable changes that have occurred in the treatment of advanced malignant melanoma over the last several years are reflected in revised National Comprehensive Cancer Network guidelines.
“Gone are the days where our active agents were interferon and dacarbazine,” said Dr.... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 8, 2016 Category: Dermatology Source Type: news
SURVEY: Telemedicine high priority, but reimbursement remains challenging
Nearly two-thirds of health care providers rank telemedicine as a top priority in 2016, a 10% increase from last year, according to a survey.
Telemedicine software company REACH Health surveyed 390 U.S. health care professionals between November 2015 and December 2015, including physicians,... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 7, 2016 Category: Dermatology Source Type: news
Phase III dupilumab data show significant improvements in atopic dermatitis
Treatment with dupilumab resulted in significant clinical improvements in adults with inadequately controlled moderate to-severe atopic dermatitis, in two phase III studies evaluating the biologic agent, according to Regeneron and Sanofi.
The phase III results of the two 16-week studies, <a... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 6, 2016 Category: Dermatology Source Type: news
Inflectra becomes first FDA-approved biosimilar for inflammatory diseases
A biosimilar version of the anti–tumor necrosis factor–alpha agent Remicade has been approved by the Food and Drug Administration, making it the first biosimilar drug approved by the agency for inflammatory diseases and just the second biosimilar it has approved.
The agency said in its April 5 <a... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 5, 2016 Category: Dermatology Source Type: news
Could value-based care raise False Claims Act liability?
As you begin to consider the switch to value-based care systems, be sure to safeguard against risks that could fuel false claims scrutiny by the government, legal experts advise.
A primary consideration is arrangements that include shared savings through coordinated care, said <a... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 5, 2016 Category: Dermatology Source Type: news
Intralesional interferon excels for challenging basal cell carcinomas
WAIKOLOA, HAWAII – Intralesional injection of interferon alfa-2b is an excellent option for the treatment of large problematic basal cell carcinomas in patients who aren’t interested in the higher-morbidity options, Dr. David L. Swanson said at the Hawaii Dermatology Seminar provided by Global... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 5, 2016 Category: Dermatology Source Type: news
State board discipline of physicians varies widely by state
The rate at which medical boards discipline physicians varies widely by state, with Delaware doctors facing four times more disciplinary actions that Massachusetts physicians, according to a review of physicians in all 50 states.
Dr. John Alexander Harris of the University of Michigan, Ann Arbor,... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 4, 2016 Category: Dermatology Source Type: news
Topical allantoin cream speeds wound healing in epidermolysis bullosa
WASHINGTON – A 6% allantoin cream has shown good results in healing wounds caused by epidermolysis bullosa (EB), with 82% of patients getting a complete closure by 2 months, in a phase IIb study.
The results of the 3 month study were good enough to propel that dose into both an open label and a... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 4, 2016 Category: Dermatology Source Type: news
What are the best, worst states for physicians?
Should your future include a move to the South? A new report finds that Mississippi ranks as the best state to practice medicine, while the District of Columbia and New York are the least doctor-friendly areas in the United States. (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 4, 2016 Category: Dermatology Source Type: news
Staph aureus drives atopic dermatitis
LOS ANGELES – Evidence is building for the hypothesis that impairments in the skin’s microbiome promote Staphylococcus aureus colonization and drive atopic dermatitis, Dr. Donald Y.M. Leung said at the annual meeting of the American Academy of Allergy, Asthma, and Immunology.
The link... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 4, 2016 Category: Dermatology Source Type: news
Severe psoriasis, kidney disease linked
WASHINGTON – Another population-based study has found a link between severe psoriasis and kidney disease – this one discovering almost a fivefold increase in the risk of immunoglobulin A nephropathy (IgAN) and a doubling in the risk of glomerular disease.
The findings suggest yet again that... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 2, 2016 Category: Dermatology Source Type: news
New topical anticholinergic beats axillary sweat
WASHINGTON – Sofpironium bromide, a newly developed “soft” anticholinergic gel, improved clinical outcomes and quality of life in patients with severe hyperhidrosis.
The drug is designed to work as an effective anticholinergic, but is metabolized and excreted much more quickly. This limits the... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 1, 2016 Category: Dermatology Source Type: news
Cutaneous lupus may raise risk of stroke, TIA
The higher risk of cardiovascular morbidity and mortality that has been repeatedly observed among patients with systemic lupus erythematosus (SLE) may extend only to stroke and transient ischemic attack among patients with disease limited to the skin and not to ischemic heart disease, heart... (Source: Skin and Allergy News)
Source: Skin and Allergy News - March 31, 2016 Category: Dermatology Source Type: news
