Experts present first recommendations for treating acne fulminans
SCOTTSDALE, ARIZ. – Patients with acne fulminans should first begin corticosteroid monotherapy before adding isotretinoin, according to the first evidence-based consensus recommendations on this disease.
Antibiotics should not be used as first line treatment or monotherapy for acne fulminans,... (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 3, 2016 Category: Dermatology Source Type: news
FDA is investigating Zecuity sumatriptan patch for reports of serious burns
The Food and Drug Administration is evaluating patient reports of serious burns and potential permanent scarring that have occurred with the use of the Zecuity patch (sumatriptan iontophoretic transdermal system) to relieve migraine headaches.
Since September 2015, a large number of patients using... (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 2, 2016 Category: Dermatology Source Type: news
Fill rates: E-prescriptions beat paper for dermatology inpatients
SCOTTSDALE, ARIZ. – Dermatology patients who received new electronic prescriptions were significantly more likely to fill them than patients given paper prescriptions at a major urban hospital, a study showed.
This is the largest study to directly measure primary nonadherence to dermatologic... (Source: Skin and Allergy News)
Source: Skin and Allergy News - May 31, 2016 Category: Dermatology Source Type: news
HPV vaccine doesn’t provide herd immunity or crossprotection
WASHINGTON – The prevalence of human papillomavirus (HPV) types 16 and 18 has significantly decreased, but only among vaccinated women; national data show no evidence that the vaccine targeting them has conferred herd immunity or encouraged a shift toward lower-risk types.
From 2003, before the... (Source: Skin and Allergy News)
Source: Skin and Allergy News - May 26, 2016 Category: Dermatology Source Type: news
Gene expression test predicts melanoma metastasis
ORLANDO – A commercially available melanoma gene expression test had a negative predictive value of 98% for metastasis, but also correctly identified patients at very high risk of disease spread.
In a retrospective study, the DecisionDx-Melanoma test, which examines 28 risk genes, showed that... (Source: Skin and Allergy News)
Source: Skin and Allergy News - May 25, 2016 Category: Dermatology Source Type: news
Oxandrolone, propranolol combo increases growth in severely burned children
CHICAGO – Combination therapy with oxandrolone and propranolol can attenuate burn-induced growth arrest and increase growth rate in severely burned children, according to findings from a prospective, randomized clinical trial.
Of 612 children with burns over at least 30% of their total body... (Source: Skin and Allergy News)
Source: Skin and Allergy News - May 24, 2016 Category: Dermatology Source Type: news
TBI prior to adoptive cell transfer added harm, no benefit
The addition of total body irradiation to nonmyeloablative chemotherapy prior to adoptive cell transfer does not provide any response or survival benefits but increases the risk of developing thrombotic microangiopathy (TMA), investigators reported.
Sequential clinical studies in the Surgery... (Source: Skin and Allergy News)
Source: Skin and Allergy News - May 23, 2016 Category: Dermatology Source Type: news
Judge says feds overstepped on ACA cost-sharing subsidies
The Obama administration suffered another legal judgment against the Affordable Care Act when a district court judge ruled that the government has wrongly spent billions of dollars to repay insurers for health insurance provided to certain low-income patients
Congress never appropriated the money... (Source: Skin and Allergy News)
Source: Skin and Allergy News - May 23, 2016 Category: Dermatology Source Type: news
Sentinel node biopsies may be useful in head and neck squamous cell carcinoma
ORLANDO – Sentinel node biopsies may be a useful staging tool for patients with cutaneous squamous cell carcinomas of the head and neck.
These patients – especially those with compromised immune systems – appear to be at sufficiently high risk of metastasis to justify the procedure, Dr. Jonathan... (Source: Skin and Allergy News)
Source: Skin and Allergy News - May 23, 2016 Category: Dermatology Source Type: news
Matrilin-2 protein distinguished BCCs from benign tumors in study
ORLANDO – Matrilin-2 – a matrix protein found in peritumoral stroma – reliably distinguished invasive basal cell carcinoma from the often difficult-to-distinguish basaloid follicular hamartoma (BFH), in a study that evaluated the protein as a marker in this setting.
The protein marked 41 of 42... (Source: Skin and Allergy News)
Source: Skin and Allergy News - May 23, 2016 Category: Dermatology Source Type: news
Stevens-Johnson syndrome, TEN not as rare as thought
SCOTTSDALE – Stevens-Johnson syndrome and toxic epidermal necrolysis are not quite as rare as previously thought, according to one of the first population-based epidemiologic studies of the disorders.
“The incidence of Stevens-Johnson syndrome appears to be higher than previously reported,... (Source: Skin and Allergy News)
Source: Skin and Allergy News - May 21, 2016 Category: Dermatology Source Type: news
For preventing AKs, 5-FU beats placebo for up to 3 years
SCOTTSDALE – A single course of topical 5-fluorouracil (5-FU) prevented 62% more actinic keratoses than placebo, and this chemopreventive effect persisted for up to 3 years, according to an analysis of the Veterans Affairs Keratinocyte Carcinoma Chemoprevention Trial (VAKCCT) trial.
Other studies... (Source: Skin and Allergy News)
Source: Skin and Allergy News - May 20, 2016 Category: Dermatology Source Type: news
FDA: No oral ketoconazole for skin, nail fungus
The Food and Drug Administration is warning health care professionals not to prescribe oral ketoconazole for patients with fungal infections of the skin and nails, because of "the risks of serious liver damage, adrenal gland problems, and harmful interactions with other medicines that... (Source: Skin and Allergy News)
Source: Skin and Allergy News - May 19, 2016 Category: Dermatology Source Type: news
Diabetic foot ulcers linked to cognitive decline
Among patients with type 2 diabetes, those with foot ulcers show cognitive impairment across all domains when compared with those without, according to a report published in Diabetes Care.
In what they described as one of the first studies to examine cognitive function in people with diabetic... (Source: Skin and Allergy News)
Source: Skin and Allergy News - May 19, 2016 Category: Dermatology Source Type: news
Pembrolizumab benefit holds long-term for some melanoma patients
The anti–PD-1 immunotherapy pembrolizumab increases long-term survival in some patients with advanced melanoma, according to updated results of KEYNOTE-001.
Among the 655 patients studied in the phase 1b trial, the 3-year overall survival rate for advanced melanoma patients treated with <a... (Source: Skin and Allergy News)
Source: Skin and Allergy News - May 18, 2016 Category: Dermatology Source Type: news
