Scientists find new pain-suppression center in the brain
Scientists identified a group of neurons in mice that blunt pain within the brain. Such neurons could be promising targets for new non-addictive therapies for chronic pain. (Source: NIH Research Matters)
Source: NIH Research Matters - June 2, 2020 Category: Research Source Type: news

Beneficial bacteria prevent recurring bacterial vaginosis
An experimental treatment for a common infection called bacterial vaginosis significantly reduced the rates of recurrence. (Source: NIH Research Matters)
Source: NIH Research Matters - June 2, 2020 Category: Research Source Type: news

Early results show benefit of remdesivir for COVID-19
Early clinical trial results support the use of remdesivir for patients with severe COVID-19 who require supplemental oxygen, but more research is needed to improve outcomes for people with COVID-19. (Source: NIH Research Matters)
Source: NIH Research Matters - June 1, 2020 Category: Research Source Type: news

How the nose decodes complex odors
Researchers showed how receptors in the nose help decode the smell of complex odor mixtures. (Source: NIH Research Matters)
Source: NIH Research Matters - May 12, 2020 Category: Research Source Type: news

New insight into regenerating prostate tissue
Progress in understanding how the prostate regenerates after hormone therapy may one day lead to improved therapies for prostate cancer. (Source: NIH Research Matters)
Source: NIH Research Matters - May 12, 2020 Category: Research Source Type: news

Alzheimer ’s gene contributes to blood-brain barrier breakdown
Damage to the blood-brain barrier may contribute to the development of Alzheimer ’s dementia in people carrying a high-risk gene variation. (Source: NIH Research Matters)
Source: NIH Research Matters - May 11, 2020 Category: Research Source Type: news

Novel coronavirus structure reveals targets for vaccines and treatments
Researchers produced a detailed picture of the part of SARS-CoV-2 —the novel coronavirus that causes COVID-19—that allows it to infect human cells. (Source: NIH Research Matters)
Source: NIH Research Matters - March 3, 2020 Category: Research Source Type: news

How a marine animal makes unlimited eggs and sperm
Findings in a marine animal called Hydractinia symbiolongicarpus could provide insight into the human reproductive system and the causes of reproductive conditions and diseases. (Source: NIH Research Matters)
Source: NIH Research Matters - March 3, 2020 Category: Research Source Type: news

When more information may not lead to better decisions
Researchers found that more information doesn ’t always help lead those who have personal experience in a subject to make better decisions. (Source: NIH Research Matters)
Source: NIH Research Matters - March 3, 2020 Category: Research Source Type: news

Immune cell metabolism altered in ME/CFS
Scientists found that some immune cells in people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) show disruptions in the way they produce and use energy. (Source: NIH Research Matters)
Source: NIH Research Matters - January 7, 2020 Category: Research Source Type: news

Scientists design device for oral delivery of injections
Scientists designed a capsule that, when taken by mouth, can deliver drugs through microneedle injections to the small intestine. (Source: NIH Research Matters)
Source: NIH Research Matters - October 29, 2019 Category: Research Source Type: news

Tiny bleeds associated with disability after brain injury
People who had traumatic microbleeds that could be seen on MRI scans were twice as likely to experience disability after a traumatic brain injury. (Source: NIH Research Matters)
Source: NIH Research Matters - October 29, 2019 Category: Research Source Type: news

Artificial pancreas improves type 1 diabetes management
An artificial pancreas system improved blood glucose control throughout the day and overnight for people with type 1 diabetes. (Source: NIH Research Matters)
Source: NIH Research Matters - October 28, 2019 Category: Research Source Type: news

ALS-related mutations prevent RNA transport in nerves
Researchers discovered that ALS-related mutations prevent RNA transport from the nucleus to other areas of nerve cells. The results suggest an avenue to investigate new treatments for diseases linked to problems with this process. (Source: NIH Research Matters)
Source: NIH Research Matters - October 15, 2019 Category: Research Source Type: news

Gut microbes affect harmful compound in red meat
Researchers identified an enzyme in gut bacteria that releases an inflammation-causing carbohydrate from meat. The findings suggest strategies to reduce the risk of certain diseases associated with eating red meat. (Source: NIH Research Matters)
Source: NIH Research Matters - October 15, 2019 Category: Research Source Type: news

African American children may need different asthma treatments
Results from a study of African American children with poorly controlled asthma contrast with those seen in other populations in previous studies. The findings highlight the importance of including people of diverse ages and races. (Source: NIH Research Matters)
Source: NIH Research Matters - October 11, 2019 Category: Research Source Type: news

Gut microbe provokes release of inflammatory substance
Researchers discovered how a gut microbe linked to Crohn ’s disease may stimulate immune cells to trigger inflammation. (Source: NIH Research Matters)
Source: NIH Research Matters - June 25, 2019 Category: Research Source Type: news

Language patterns may predict psychosis
In a proof-of-concept study, spoken language patterns predicted which people at risk for psychosis would progress to full psychosis within two years with 93% accuracy. (Source: NIH Research Matters)
Source: NIH Research Matters - June 25, 2019 Category: Research Source Type: news

Social acceptance helps mental health after war trauma
Researchers found that acceptance and support from community and family may lessen the toll of mental health conditions experienced by former child soldiers. (Source: NIH Research Matters)
Source: NIH Research Matters - June 24, 2019 Category: Research Source Type: news

Blood-brain barrier test may predict dementia
A new study suggests that measuring the breakdown of the blood-brain barrier could be an early way to test for cognitive impairment from Alzheimer ’s disease and other causes. (Source: NIH Research Matters)
Source: NIH Research Matters - January 29, 2019 Category: Research Source Type: news

Patch replaces damaged retinal cells
Researchers developed a biodegradable patch for replacing diseased cells in the eye with healthy ones. The findings provide the basis for preliminary safety tests of the method in people. (Source: NIH Research Matters)
Source: NIH Research Matters - January 29, 2019 Category: Research Source Type: news

Printed scaffolds promote spinal cord repair in rats
Researchers used 3D printing technology to create a scaffold that helped promote the growth of new nerve cells in rats and restore some limb movement after spinal cord injury. (Source: NIH Research Matters)
Source: NIH Research Matters - January 29, 2019 Category: Research Source Type: news

Biodegradable, implantable pressure sensors
Researchers engineered a biodegradable pressure sensor from materials used in FDA-approved medical implants and successfully implanted it into mice. (Source: NIH Research Matters)
Source: NIH Research Matters - January 30, 2018 Category: Research Source Type: news

Blood test detects several cancer types
Researchers developed a blood test that can detect signs of eight common solid tumors. With further development, the test could allow for earlier cancer detection. (Source: NIH Research Matters)
Source: NIH Research Matters - January 29, 2018 Category: Research Source Type: news

Enzyme drives middle-age weight and fitness changes
Scientists identified an enzyme in animal studies whose activity promotes weight gain and the loss of fitness starting in mid-life. The findings could lead to improved weight-loss drugs. (Source: NIH Research Matters)
Source: NIH Research Matters - May 9, 2017 Category: Research Source Type: news

Protein involved in hearing loss recovery
A study with mice found that a protein called FOXO3 is involved in recovery from noise-induced hearing loss. The results suggest new potential treatments approaches. (Source: NIH Research Matters)
Source: NIH Research Matters - May 8, 2017 Category: Research Source Type: news

Novel insecticide blocks mosquitoes ’ ability to urinate
Researchers identified a new insecticide for mosquitoes that blocks kidney function. Further research will be needed to assess its impact on humans and beneficial insects. (Source: NIH Research Matters)
Source: NIH Research Matters - December 13, 2016 Category: Research Source Type: news

Social status alters immune response in monkeys
A study in rhesus monkeys found that social status can cause changes in the immune system that may affect overall health, and that these changes can be reversed. (Source: NIH Research Matters)
Source: NIH Research Matters - December 13, 2016 Category: Research Source Type: news

Recalling temporary memories
Researchers were able to restore recently “set aside” memories. The study provides insight into how the brain may temporarily store information for later recall. (Source: NIH Research Matters)
Source: NIH Research Matters - December 12, 2016 Category: Research Source Type: news

Novel gene-editing method improves vision in blind rats
A targeted gene-replacement technique partially restored vision in blind rats and holds promise as a potential tool for gene therapy. (Source: NIH Research Matters)
Source: NIH Research Matters - December 6, 2016 Category: Research Source Type: news

Exploring the genome of the river blindness parasite
Researchers decoded the genome of the parasite that causes the skin and eye infection known as river blindness. The findings could lead to improved ways to treat and prevent the disease. (Source: NIH Research Matters)
Source: NIH Research Matters - December 6, 2016 Category: Research Source Type: news

Palliative care improves quality of life in cancer patients
Patients who received palliative care during a bone marrow transplant reported a better quality of life and reduced symptoms during hospitalization. (Source: NIH Research Matters)
Source: NIH Research Matters - December 5, 2016 Category: Research Source Type: news

Visualizing a cancer drug target at atomic resolution
Using cryo-electron microscopy, researchers viewed the binding of a potential drug to a key protein in cancer cells. The study shows how the technique can help in drug development. (Source: NIH Research Matters)
Source: NIH Research Matters - February 9, 2016 Category: Research Source Type: news

How cystic fibrosis promotes lung infections
Scientists discovered how cystic fibrosis raises the risk for lung infections. The findings also identify a novel potential therapeutic target. (Source: NIH Research Matters)
Source: NIH Research Matters - February 9, 2016 Category: Research Source Type: news

Restoring microbes in infants born by cesarean section
In a pilot study, researchers enriched the microbes of babies delivered by C-section to levels more typical of babies born vaginally. The health impacts remain to be studied. (Source: NIH Research Matters)
Source: NIH Research Matters - February 8, 2016 Category: Research Source Type: news

Encapsulated cells treat diabetes in mice
Researchers developed a way to encase insulin-producing cells and successfully treat diabetic mice. The findings are a step forward for developing type 1 diabetes treatments. (Source: NIH Research Matters)
Source: NIH Research Matters - February 2, 2016 Category: Research Source Type: news

Dizziness and balance problems common in U.S. kids
More than 1 in 20 U.S. children have a dizziness or balance problem, and only one-third of them had received treatment in the previous year, scientists report. (Source: NIH Research Matters)
Source: NIH Research Matters - February 2, 2016 Category: Research Source Type: news

A biological mechanism for schizophrenia
Scientists identified the mechanism behind genetic variations that had been linked to schizophrenia in previous studies. The findings might lead to new clinical approaches. (Source: NIH Research Matters)
Source: NIH Research Matters - February 1, 2016 Category: Research Source Type: news

Circuit tweak enhances social memory in mice
By stimulating a specific brain circuit in male mice, researchers boosted the animal’s ability to remember unfamiliar female mice days later. (Source: NIH Research Matters)
Source: NIH Research Matters - January 26, 2016 Category: Research Source Type: news

Glaucoma-related genes revealed
A genomic analysis gives insights into the underlying disease mechanisms for most common type of glaucoma and suggests new targets for potential therapies. (Source: NIH Research Matters)
Source: NIH Research Matters - January 26, 2016 Category: Research Source Type: news

Trying to conceive after a pregnancy loss
Researchers found no evidence to support the common idea that couples should wait for 3 months after an uncomplicated early pregnancy loss before trying to conceive again. (Source: NIH Research Matters)
Source: NIH Research Matters - January 25, 2016 Category: Research Source Type: news

Gene editing improves muscle in mice with muscular dystrophy
Researchers demonstrated how the CRISPR/Cas9 gene-editing system could potentially be used to correct mutations responsible for muscular dystrophy and other genetic disorders. (Source: NIH Research Matters)
Source: NIH Research Matters - January 12, 2016 Category: Research Source Type: news

Boosting brain’s waste disposal system may slow neurodegenerative diseases
A mouse study suggests that activating the cell’s waste disposal system during early stages of neurodegenerative diseases may help lessen brain damage and dementia. (Source: NIH Research Matters)
Source: NIH Research Matters - January 12, 2016 Category: Research Source Type: news

Infertility treatments don’t appear to affect children’s development
Children conceived using infertility treatments were no more likely to have a developmental delay by age 3 than those conceived without such treatments. (Source: NIH Research Matters)
Source: NIH Research Matters - January 11, 2016 Category: Research Source Type: news

2015 Research Highlights — Insights from the Lab
Noteworthy NIH advances in basic research include charting human genetic variation across the globe, the discovery of lymphatic vessels in the central nervous system, and insights into energy-burning fat cells. (Source: NIH Research Matters)
Source: NIH Research Matters - December 21, 2015 Category: Research Source Type: news

2015 Research Highlights — Promising Medical Advances
NIH findings with potential for enhancing human health include advances in Ebola research, progress in fighting HIV, and the development of custom 3-D printed nerve scaffolds to aid tissue regeneration. (Source: NIH Research Matters)
Source: NIH Research Matters - December 21, 2015 Category: Research Source Type: news

2015 Research Highlights — Clinical Breakthroughs
NIH accomplishments in the prevention, diagnosis, and treatment of human disease. These include a test to tailor breast cancer tumor treatments, a noninvasive treatment to help paralyzed men gain movement, and a tool that may predict suicide risk. (Source: NIH Research Matters)
Source: NIH Research Matters - December 18, 2015 Category: Research Source Type: news

How taste is perceived in the brain
By manipulating areas of the mouse brain that represent sweet and bitter taste, researchers showed that responses to sweet and bitter tastes are hardwired into the brain. (Source: NIH Research Matters)
Source: NIH Research Matters - December 7, 2015 Category: Research Source Type: news

Engineering functional vocal cord tissue
Researchers grew human cells into functional vocal cord tissue in the laboratory—an important preliminary step toward restoring voice function to people with injured vocal cords. (Source: NIH Research Matters)
Source: NIH Research Matters - December 7, 2015 Category: Research Source Type: news

Breastfeeding may help prevent type 2 diabetes after gestational diabetes
A study suggests that breastfeeding may help women with a history of gestational diabetes from later developing type 2 diabetes. (Source: NIH Research Matters)
Source: NIH Research Matters - December 4, 2015 Category: Research Source Type: news