Primarily home-based cognitive behavior therapy as effective as standard therapy for treatment of irritable bowel syndrome
New research has shown that a mainly home-based behavior therapy regimen to treat irritable bowel syndrome (IBS) is just as effective as a similar, more expensive, strictly clinic-based therapy, and is more effective than an education-only approach.  (Source: NIDDK News)
Source: NIDDK News - March 18, 2019 Category: Endocrinology Source Type: news

Finding a new home —how good (and bad) bacteria colonize the gut
Three studies have revealed details of what happens when a community of bacteria inhabiting the gut is disrupted and then rebuilt by a change in diet or by adding bacteria from a healthy donor, providing valuable insights that could help with the design of microbe-based therapies for the treatment of gastrointestinal infections and other digestive diseases. (Source: NIDDK News)
Source: NIDDK News - March 18, 2019 Category: Endocrinology Source Type: news

Kidney protein could expand the window for developmental nephron production
A study in mice showed that a partial reduction of the protein hamartin in the developing kidney leads to larger numbers of nephrons —the basic functional unit of the kidney.  (Source: NIDDK News)
Source: NIDDK News - March 18, 2019 Category: Endocrinology Source Type: news

Understanding calorie burning in early pregnancy —moving toward improving health for mothers and children
New research is shedding light on calorie consumption and calorie burning in early pregnancy in women with obesity, which could inform strategies to promote healthy gestational weight gain and reduce racial disparities in pregnancy outcomes.  (Source: NIDDK News)
Source: NIDDK News - March 18, 2019 Category: Endocrinology Source Type: news

Zebrafish employ cellular shield to protect blood stem cells from damaging ultraviolet light
While studying the blood stem cells that reside in the kidney of the zebrafish embryo, researchers observed that cells called melanocytes were positioned above the stem cells in an umbrella pattern, and subsequently showed this umbrella served as a shield protecting stem cells from damaging ultraviolet (UV) light.  (Source: NIDDK News)
Source: NIDDK News - March 18, 2019 Category: Endocrinology Source Type: news

Studies show difficulty in treating type 2 diabetes in youth and highlight unique aspects of the disease in young people
New research reveals that the only two medications approved for pediatric type 2 diabetes do not prevent rapid progression of prediabetes or recent onset type 2 diabetes in young people with the disease; however, analyses comparing metabolic tests of adults in a companion study and the youth study participants are helping scientists understand how the disease differs with age, which may one day lead to better treatment approaches. (Source: NIDDK News)
Source: NIDDK News - March 18, 2019 Category: Endocrinology Source Type: news

Preserving insulin production in people with newly diagnosed type 1 diabetes
Researchers have discovered that treatment with a medicine that suppresses the immune system, called anti-thymocyte globulin (ATG), preserved insulin production and improved blood glucose (sugar) control for at least a year in people with newly diagnosed type 1 diabetes, as compared to placebo (no medicine).  (Source: NIDDK News)
Source: NIDDK News - March 18, 2019 Category: Endocrinology Source Type: news

Treatment for common urinary ailment no longer carved in stone
Newly published results from a large clinical trial indicate that a drug frequently used in the emergency room to treat people with urinary stone disease has no benefit if the stones are below a certain size.  (Source: NIDDK News)
Source: NIDDK News - March 18, 2019 Category: Endocrinology Source Type: news

Story of discovery: newborn screening for lysosomal storage diseases
Newborn screening for lysosomal storage diseases (Source: NIDDK News)
Source: NIDDK News - March 18, 2019 Category: Endocrinology Source Type: news

Story of discovery: getting a Notch up on cord blood cell transplantation
Researchers supported by NIDDK have discovered key factors that promote blood stem cell growth and maturation, and, with these insights, have developed ways to expand the numbers of cells from cord blood for use in transplants. (Source: NIDDK News)
Source: NIDDK News - March 18, 2019 Category: Endocrinology Source Type: news

Story of discovery: discoveries moving towards understanding and personalized treatment of inflammatory bowel disease
Researchers have discovered ways in which the bacteria and other microbes that reside in the gut —the gut microbial community or microbiome—can affect risk of IBD, and efforts such as NIDDK’s IBD Genetics Consortium are shedding new light on the genetic foundations of the disease. (Source: NIDDK News)
Source: NIDDK News - March 18, 2019 Category: Endocrinology Source Type: news

Treatment of depression for people with end-stage kidney disease undergoing hemodialysis
(Source: NIDDK News)
Source: NIDDK News - February 26, 2019 Category: Endocrinology Source Type: news

Metabolism, memory, and the role of insulin in the brain
(Source: NIDDK News)
Source: NIDDK News - February 14, 2019 Category: Endocrinology Source Type: news

Streaming fluid across kidney organoids —mini kidney-like structures—grown on a chip drives their maturation
(Source: NIDDK News)
Source: NIDDK News - February 11, 2019 Category: Endocrinology Source Type: news

Novel imaging technology sheds light on how type 1 diabetes progresses
(Source: NIDDK News)
Source: NIDDK News - January 31, 2019 Category: Endocrinology Source Type: news