Case 2: An Infant with Poor Weight Gain and Persistent Tachycardia
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - June 1, 2017 Category: Pediatrics Authors: Krasaelap, A., Kannikeswaran, N. Tags: Pediatric Drug Labeling Update Index of Suspicion in the Nursery Source Type: news

Case 1: The Inconsolable Infant in the NICU
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - June 1, 2017 Category: Pediatrics Authors: Kurada, S., Joseph, T. Tags: Pediatric Drug Labeling Update Index of Suspicion in the Nursery Source Type: news

Neonatal Urogenital Issues: Evaluation and Management
This article addresses renal, bladder, and genital abnormalities noted in newborns. Neonatal management of exstrophy/epispadias complex, prune belly syndrome, and myelomeningocele is discussed. The differential diagnoses of abdominal masses and introital masses are presented. (Source: NeoReviews recent issues)
Source: NeoReviews recent issues - June 1, 2017 Category: Pediatrics Authors: Vricella, G. J., Coplen, D. E. Tags: Pediatric Drug Labeling Update Articles Source Type: news

Neonatal Hypertension
This article reviews the parameters defining normal and elevated blood pressures in neonates using current available data, etiology and risk factors, approach to investigation, and management of neonatal hypertension. (Source: NeoReviews recent issues)
Source: NeoReviews recent issues - June 1, 2017 Category: Pediatrics Authors: Mistry, K., Gupta, C. Tags: Pediatric Drug Labeling Update Articles Source Type: news

Congenital Diseases of the Kidneys: Prognosis and Treatments
Chronic kidney disease (CKD) is a growing public health problem with a huge economic burden on society. In children, congenital anomalies of the kidneys and urinary tract (CAKUT) are the most common cause for CKD. Normal development of the kidneys and urinary tract progresses through a complex series of events and requires the expression of key transcription factors to occur with precision in the fetus. It is now known that many genetic defects can lead to CAKUT. Most CAKUT can be identified prenatally with antenatal ultrasonography, and in cases of severe oligohydramnios, prenatal options such as vesicoamniotic shunting a...
Source: NeoReviews recent issues - June 1, 2017 Category: Pediatrics Authors: Feldenberg, R., Beck, A. Tags: Pediatric Drug Labeling Update Articles Source Type: news

Recomendaciones del VI Consenso Clinico de SIBEN para la Hipertension Pulmonar Persistente del Recien Nacido
This article summarizes the recommendations of the 6th Clinical Consensus on Persistent Pulmonary Hypertension of the Newborn of the Ibero-American Society of Neonatology (SIBEN). It describes the etiology, pathophysiology, and treatment (including maintaining the optimal oxygenation, alveolar ventilation, optimal perfusion, and use of pulmonary vasodilators, such as inhaled nitric oxide and sildenafil, as well as emerging therapies). It ends with a summary of the SIBEN consensus clinical recommendations, as a practical way to keep improving the care of our newborns. Resumen La hipertensión pulmonar persistente del...
Source: NeoReviews recent issues - May 1, 2017 Category: Pediatrics Authors: Golombek, S., Sola, A., Lemus, L., y Miembros del Consenso de SIBEN Tags: Pediatric Drug Labeling Update Articles Source Type: news

Newborn with a Large Exophytic Mass on the Head
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - May 1, 2017 Category: Pediatrics Authors: Lau, S. S. M., Chandrasekaran, P. Tags: Pediatric Drug Labeling Update Visual Diagnosis Source Type: news

Legal Briefs: Was the Intracardiac Thrombus Secondary to an Unnecessary Umbilical Venous Catheter?
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - May 1, 2017 Category: Pediatrics Authors: Sims, M. E. Tags: Pediatric Drug Labeling Update Index of Suspicion in the Nursery Source Type: news

Strip of the Month: A Multiparous Patient with Twins Requiring Urgent Operative-assisted Vaginal Delivery
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - May 1, 2017 Category: Pediatrics Authors: Mulla, B. M., Young, B. C. Tags: Pediatric Drug Labeling Update Index of Suspicion in the Nursery Source Type: news

Case 2: Herpes Simplex Virus Infection in a Preterm Infant and Complications
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - May 1, 2017 Category: Pediatrics Authors: Kojima, K., Schein, R., Karna, P. Tags: Pediatric Drug Labeling Update Index of Suspicion in the Nursery Source Type: news

Case 1: A Term Infant with Respiratory Distress
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - May 1, 2017 Category: Pediatrics Authors: Shridhar, L. C. G., Kumar, L. C. R., Sodhi, C. K. Tags: Pediatric Drug Labeling Update Index of Suspicion in the Nursery Source Type: news

Neonatal Genomics: Part 2--Applications
The next-generation sequencing techniques described in Part 1 of this review can be used to sequence single genes, panels of genes, whole exomes, or whole genomes. These tests can be used for both diagnostic and screening purposes in the newborn nursery and NICU. As the cost and turnaround time for genetic testing decrease, the use of sequencing data will become more prevalent and can influence the diagnostic evaluation and care of the newborn. The use of genomic data for newborn screening is more controversial but also has potential usefulness in expanding the capabilities of current, predominantly analyte-based newborn s...
Source: NeoReviews recent issues - May 1, 2017 Category: Pediatrics Authors: Wojcik, M. H., Parad, R. B. Tags: Pediatric Drug Labeling Update Articles Source Type: news

Neonatal Genomics: Part 1--Basics and Definitions
As genomic medicine is increasingly incorporated into clinical practice across all disciplines, an understanding of basic genetic concepts is important for the neonatologist. There are many different ways in which variations in the human genetic sequence, which comprises the genome, can lead to disease. Gene sequencing through the use of Sanger sequencing or next-generation sequencing technology can detect disease-causing variants and can be performed across the entire human genome in whole genome sequencing or across only the coding regions of the human genome in whole exome sequencing. (Source: NeoReviews recent issues)
Source: NeoReviews recent issues - May 1, 2017 Category: Pediatrics Authors: Wojcik, M. H., Parad, R. B. Tags: Pediatric Drug Labeling Update Articles Source Type: news

Pumpless Extracorporeal Support of the Preterm Infant: Bridging Fetal and Postnatal Physiology
Preterm birth is a major cause of neonatal mortality and childhood morbidity and remains an unsolved clinical challenge despite advances in neonatal care. The preterm infant needs to be supported in an extracorporeal system physiologically analogous to the sterile fluid intrauterine environment. This would support ongoing growth and organ maturation with the potential to substantially improve survival and reduce morbidity. A physiologic system would require the ability to achieve gas exchange via the umbilical circulation, with the fetal heart acting as the pump that drives circuit flow. Previous efforts at developing such...
Source: NeoReviews recent issues - May 1, 2017 Category: Pediatrics Authors: Partridge, E. A., Davey, M. G., Hornick, M. A., Flake, A. W. Tags: Pediatric Drug Labeling Update Articles Source Type: news

Late Preterm and Early Term Birth: At-risk Populations and Targets for Reducing Such Early Births
The risks of late preterm (LPT) and early term (ET) birth have been recognized during the last decade. Increased awareness accompanied by efforts to reduce elective delivery before 39 weeks of gestation have led to a decline in LPT/ET births. Despite this success, strategies to identify and reduce preventable LPT/ET births using traditional and novel prevention methods are still needed. Because preterm birth is a common endpoint associated with many different preventable and nonpreventable causes, the efforts for reducing such early births must be multifaceted. For neonates born LPT/ET, there is an inverse relationship bet...
Source: NeoReviews recent issues - May 1, 2017 Category: Pediatrics Authors: Kardatzke, M. A., Rose, R. S., Engle, W. A. Tags: Pediatric Drug Labeling Update Articles Source Type: news