Appropriate Management of the Nonvigorous Meconium-Stained Newborn Meconium
Before 2015, major changes in Neonatal Resuscitation Program (NRP) recommendations not supporting previously endorsed antepartum, intrapartum and postpartum interventions to prevent meconium aspiration syndrome were based on adequately powered multicenter randomized controlled trials. The 2015 and 2020 American Heart Association guidelines and 7th and 8th edition of NRP suggest not performing routine intubation and tracheal suctioning of nonvigorous meconium-stained newborns. However, this was given as a weak recommendation with low-certainty evidence. The purpose of this review is to summarize the evidence and explore the...
Source: NeoReviews recent issues - April 1, 2022 Category: Pediatrics Source Type: news

Term Male Infant with Abdominal Mass
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - April 1, 2022 Category: Pediatrics Source Type: news

A Case of Dropped Beats: Management of a Common Fetal Arrhythmia
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - April 1, 2022 Category: Pediatrics Source Type: news

Newborn with Microcephaly
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - April 1, 2022 Category: Pediatrics Source Type: news

A Nonimmune Hydrops Case
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - April 1, 2022 Category: Pediatrics Source Type: news

Updates for the Neonatal Resuscitation Program and Resuscitation Guidelines
Although most newborns require no assistance to successfully transition to extrauterine life, the large number of births each year and limited ability to predict which newborns will need assistance means that skilled clinicians must be prepared to respond quickly and efficiently for every birth. A successful outcome is dependent on a rapid response from skilled staff who have mastered the cognitive, technical, and behavioral skills of neonatal resuscitation. Since its release in 1987, over 4.5 million clinicians have been trained by the American Heart Association and American Academy of Pediatrics Neonatal Resuscitation Pr...
Source: NeoReviews recent issues - April 1, 2022 Category: Pediatrics Source Type: news

Ethical Considerations in Neonatal Research
Children are considered a vulnerable population and have traditionally been excluded from research studies. This exclusion of children in general, and neonates in particular, from clinical research hampers the development of safe and effective therapies in this population. However, research involving children (including infants) is essential to guide therapy and optimize care. Neonatal research is complex, time intensive, difficult and expensive to conduct, and raises some unique ethical considerations. The complexity of research in this population is highlighted by the fear of causing harm to fragile sick infants which ha...
Source: NeoReviews recent issues - March 1, 2022 Category: Pediatrics Source Type: news

Abnormal Newborn Screen During a Pandemic
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - March 1, 2022 Category: Pediatrics Source Type: news

A Term Infant with a Murmur and Dysmorphic Features
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - March 1, 2022 Category: Pediatrics Source Type: news

A Newborn with an Incidental Finding on Cranial Ultrasonography
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - March 1, 2022 Category: Pediatrics Source Type: news

Urinary Tract Dilation in the Fetus and Neonate
Urinary tract dilation (UTD), previously known as hydronephrosis, is the most common congenital condition identified on prenatal ultrasonography. UTD can be physiologic and resolve spontaneously or can be caused by various congenital anomalies of the urinary tract, which can lead to renal failure if not treated properly. In 2014, a multidisciplinary consensus group established UTD definitions, a classification system, and a standardized scheme for perinatal evaluation. Various imaging modalities are available to help diagnose the cause of UTD in fetuses and neonates and to help identify those patients who may benefit from ...
Source: NeoReviews recent issues - March 1, 2022 Category: Pediatrics Source Type: news

Fluid Homeostasis and Diuretic Therapy in the Neonate
Understanding physiologic water balance and homeostasis mechanisms in the neonate is critical for clinicians in the NICU as pathologic fluid accumulation increases the risk for morbidity and mortality. In addition, once this process occurs, treatment is limited. In this review, we will cover fluid homeostasis in the neonate, explain the implications of prematurity on this process, discuss the complexity of fluid accumulation and the development of fluid overload, identify mitigation strategies, and review treatment options. (Source: NeoReviews recent issues)
Source: NeoReviews recent issues - March 1, 2022 Category: Pediatrics Source Type: news

Genetic Etiologies, Diagnosis, and Management of Neonatal Cystic Kidney Disease
Fetal kidney development is a complex and carefully orchestrated process. The proper formation of kidney tissue involves many transcription factors and signaling pathways. Pathogenic variants in the genes that encodethese factors and proteins can result in neonatal cystic kidney disease. Advancements in genomic sequencing have allowed us to identify many of these variants and better understand the genetic underpinnings for an increasing number of presentations of childhood kidney disorders. This review discusses the genes essential in kidney development, particularly those involved in the structure and function of primary ...
Source: NeoReviews recent issues - March 1, 2022 Category: Pediatrics Source Type: news

Umbilical Cord Entanglement
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - March 1, 2022 Category: Pediatrics Source Type: news

Preterm Infant with Craniofacial Dysmorphic Features and Posture
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - March 1, 2022 Category: Pediatrics Source Type: news