Substance abuse worsens course of first-episode psychosis
Patients with first-episode psychosis who also present with substance abuse have a higher rate of hospitalisation after 12 months than their peers who do not, an Italian study reports. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 25, 2014 Category: Psychiatry Source Type: news

Factors predicting disengagement from psychosis early intervention identified
A study of first-episode psychosis patients in Hong Kong has found that those with fewer negative symptoms at presentation and poor medication compliance were more likely than others to disengage from an early intervention program. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 21, 2014 Category: Psychiatry Source Type: news

Comorbid OCD and bipolar disorder should be treated as mood disorder
Most patients with both bipolar disorder and obsessive–compulsive disorder should be treated as having bipolar disorder, researchers suggest. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 21, 2014 Category: Psychiatry Source Type: news

Support for progranulin role in bipolar disorder
Researchers have found reduced levels of plasma progranulin in patients with bipolar disorder, strengthening evidence for its possible role as a biomarker for the condition. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 20, 2014 Category: Psychiatry Source Type: news

Psychotherapies have specific effects on psychosis symptoms
There are small but robust differences in the effects of different psychotherapies on psychosis symptoms, say the authors of a meta-analysis. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 20, 2014 Category: Psychiatry Source Type: news

Stereotype awareness impacts self-esteem in schizophrenia
Patients with psychosis with higher self-esteem have less awareness of the stereotypes associated with mental health patients and their families, research shows. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 19, 2014 Category: Psychiatry Source Type: news

Mixed state specifier in DSM-5 overlooks the core features
The replacement of “mixed episodes” with “mixed features” in DSM-5 in order to counter a lack of specificity overlooks two of the core features of mixed states, suggests research published in the Journal of Affective Disorders. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 19, 2014 Category: Psychiatry Source Type: news

Verbal memory may signal disease course in first-episode psychosis
Verbal memory appears to be a predictor of clinical remission in patients with first-episode psychosis, according to Canadian researchers writing in Schizophrenia Research. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 17, 2014 Category: Psychiatry Source Type: news

Interhemispheric disconnectivity highlighted in bipolar disorder
Research shows that patients with bipolar I disorder have reduced white matter integrity, including in the corpus callosum, which connects the brain’s hemispheres. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 17, 2014 Category: Psychiatry Source Type: news

Heritable bipolar phenotypes pinned down
A large study has pinpointed brain and behavioural traits that are genetically influenced and associated with bipolar I disorder. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 14, 2014 Category: Psychiatry Source Type: news

‘Healthy living’ programme fails to lower BMI in overweight psychosis patients
A “healthy living” intervention focused on exercise and diet has failed to impact body mass index in overweight people with psychosis when evaluated in the setting of a randomised controlled trial. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 14, 2014 Category: Psychiatry Source Type: news

Consistent mania monitoring during perinatal period warranted
Pregnant and postpartum women with bipolar disorder experience clinically severe symptoms, suggesting the need for continued monitoring of mania during this time, say researchers. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 13, 2014 Category: Psychiatry Source Type: news

Common mutations produce typical schizophrenia brain changes
Mutations in dopamine-related genes have a dose-response effect on prefrontal activation during emotional response inhibition in healthy adults, a study shows. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 13, 2014 Category: Psychiatry Source Type: news

Rhythmicity of activity linked to bipolar mania
Circadian rhythm disturbances are associated with bipolar disorder, and particularly with mania, indicate study findings. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 12, 2014 Category: Psychiatry Source Type: news

Urinary tract infections linked to acute psychosis relapse
Patients with an acute episode of psychosis have a high incidence of urinary tract infections, report researchers. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 12, 2014 Category: Psychiatry Source Type: news