Icotinib matches gefitinib in NSCLC second or third line
Icotinib has been found to be noninferior to gefitinib in patients with non-small-cell lung cancer, according to reports from the phase III Chinese double-blind ICOGEN study. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - September 26, 2013 Category: Cancer & Oncology Source Type: news

Dental caries show ‘unexpected’ relationship with head and neck cancer
People with dental caries have a reduced risk for developing head and neck squamous cell carcinoma, a large case-control study has found. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - September 25, 2013 Category: Cancer & Oncology Source Type: news

Immune marker prognostic after non-clear cell RCC surgery
The preoperative neutrophil-to-lymphocyte ratio is associated with disease-free survival in patients undergoing resection of localized non-clear cell renal cell carcinoma, research shows. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - September 24, 2013 Category: Cancer & Oncology Source Type: news

Amendment to renal cancer TNM staging proposed
Patients with pT3a renal cell carcinoma have markedly worse survival rates if they have both fat invasion and renal vein thrombosis, rather than just one of these factors, a study shows. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - September 24, 2013 Category: Cancer & Oncology Source Type: news

Inflammatory marker may highlight aggressive RCC treatment need
Patients with metastatic renal cell carcinoma who have high preoperative levels of the inflammatory marker C-reactive protein may need intensive multimodal treatment to optimize their survival, say researchers. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - September 24, 2013 Category: Cancer & Oncology Source Type: news

Metastatic site impacts survival in targeted RCC treatment
Bone and liver metastases may have the heaviest impact on the survival of patients receiving targeted therapy for metastatic renal cell carcinoma, suggest data from the International Metastatic Renal Cell Carcinoma Database Consortium. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - September 24, 2013 Category: Cancer & Oncology Source Type: news

Swallow therapy combats post-radiotherapy dysphagia
Swallowing exercises can help to minimize the risk for dysphagia in patients undergoing radiotherapy for head and neck cancer, a case study suggests. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - September 20, 2013 Category: Cancer & Oncology Source Type: news

Gene variations predict breast cancer sleep disturbance
Researchers have identified cytokine gene variations in women with breast cancer that may help to identify those at increased risk for sleep disturbance following surgery. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - September 16, 2013 Category: Cancer & Oncology Source Type: news

GGO-dominant lung tumors have excellent prognosis
Ground glass opacity-dominant clinical stage IA lung adenocarcinoma is a low-grade malignancy with an “excellent” prognosis, Japanese researchers believe. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - September 11, 2013 Category: Cancer & Oncology Source Type: news

Pemetrexed-erlotinib shows second-line efficacy in advanced NSCLC
Combination therapy with pemetrexed and erlotinib significantly improves progression-free survival as compared with either drug alone in patients with advanced non-squamous non-small-cell lung cancer, a phase II study has found. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - September 9, 2013 Category: Cancer & Oncology Source Type: news

Assay aids ALK fusion detection in lung adenonocarcinoma
A fully automated immunochemistry assay is highly sensitive and specific for detecting anaplastic lymphoma kinase fusion in primary lung adenocarcinomas, Chinese researchers report. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - September 7, 2013 Category: Cancer & Oncology Source Type: news

Prophylactic cranial irradiation beneficial in elderly SCLC patients
Prophylactic cranial irradiation improves survival in elderly patients with limited-stage small-cell lung cancer, analysis of US epidemiologic data indicates. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - September 6, 2013 Category: Cancer & Oncology Source Type: news

Albumin-bound paclitaxel has favorable risk–benefit profile in NSCLC
Albumin-bound paclitaxel plus carboplatin is an effective and well-tolerated first-line treatment in patients with advanced non-small-cell lung cancer, irrespective of histology, study results show. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - August 29, 2013 Category: Cancer & Oncology Source Type: news

Tumor vessel density linked to mRCC treatment response
Changes in tumor vessel density correlate with response and resistance to anti-angiogenic therapy in patients with metastatic renal cell carcinoma, study findings suggest. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - August 28, 2013 Category: Cancer & Oncology Source Type: news

Muscle density improves mRCC prognosis prediction
Patients with metastatic renal cell carcinoma treated with targeted therapies have a better prognosis if they also have a high quality of muscle, study findings indicate. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - August 28, 2013 Category: Cancer & Oncology Source Type: news