Plasma microRNA test boosts lung cancer screening
The ability to screen for lung cancer is improved by the development of a plasma 24-microRNA signature classifier, research suggests. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - February 28, 2014 Category: Cancer & Oncology Source Type: news

H4 receptor activation plays part in NSCLC progression
Histamine H4 receptor activation decreases epithelial-to-mesenchymal transmission in non-small-cell lung cancer, Chinese research shows. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - February 27, 2014 Category: Cancer & Oncology Source Type: news

Novel SCLC tumour suppressor gene discovered
Inactivation of the MYC-associated factor X gene, MAX, may play a significant role in the development of small-cell lung cancer, scientists believe. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - February 26, 2014 Category: Cancer & Oncology Source Type: news

Perioperative blood transfusion worsens kidney cancer patients’ survival
Patients who receive blood transfusions around the time of their surgery for nonmetastatic renal cell carcinoma have a worse chance of survival than those who do not, results of a large US study suggest. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - February 24, 2014 Category: Cancer & Oncology Source Type: news

Sedentary behaviour has unclear link with prostate cancer risk
Sedentary behaviour is not a clearcut risk factor for prostate cancer, analysis of a large population-based cohort indicates. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - February 24, 2014 Category: Cancer & Oncology Source Type: news

Partial nephrectomy may offer younger renal cancer patients survival advantage
Partial nephrectomy may offer younger patients with localized renal cancer a distinct survival advantage compared with the complete removal of the kidney, US research suggests. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - February 24, 2014 Category: Cancer & Oncology Source Type: news

Advanced age should not preclude sunitinib use for mRCC
Elderly kidney cancer patients benefit from sunitinib therapy just as much as their younger counterparts, a retrospective analysis of six clinical trials shows. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - February 21, 2014 Category: Cancer & Oncology Source Type: news

Altering sunitinib dosing schedule improves tolerability
Shortening the time that patients with advanced renal cell carcinoma are on and off treatment with sunitinib improves the drug’s overall tolerability without affecting its efficacy, say Japanese researchers. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - February 21, 2014 Category: Cancer & Oncology Source Type: news

EGFR–TKI tumour response predicts NSCLC survival
A partial or complete response to epidermal growth factor receptor tyrosine kinase inhibitor therapy is significantly associated with survival in patients with non-small-cell lung cancer, research suggests. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - February 20, 2014 Category: Cancer & Oncology Source Type: news

Nintedanib plus docetaxel shows second-line efficacy in recurrent NSCLC
Nintedanib plus docetaxel offers significant efficacy in patients with non-small-cell lung cancer who experience disease progression after first-line chemotherapy, phase III study results show. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - February 19, 2014 Category: Cancer & Oncology Source Type: news

Afatinib ‘first line’ for advanced mutation-positive lung cancer
Afatinib should be given as a first-line treatment for Asian patients with advanced, epidermal growth factor receptor mutation-positive, non-small-cell lung cancer, researchers recommend. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - February 17, 2014 Category: Cancer & Oncology Source Type: news

Splicing findings offer lung cancer clues
Researchers from Spain have identified several new splicing events regulated by the oncogenic splicing factor SRSF1 in lung cancer, suggesting that their dysregulation is involved in the pathogenesis of the disease. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - February 4, 2014 Category: Cancer & Oncology Source Type: news

Primary tumor, node location important in stage III NSCLC prognosis
Researchers from Japan say that classifying clinical mediastinal lymph node status based on the location of the primary tumor and the node involved could improve prognosis in stage III non-small-cell lung cancer compared with pathologic node status. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - February 3, 2014 Category: Cancer & Oncology Source Type: news

Mesothelin expression prognostic in lung adenocarcinoma
Mesothelin expression is a significant predictor for tumor aggression in patients with lung adenocarcinoma, suggest study findings published in Clinical Cancer Research. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - January 31, 2014 Category: Cancer & Oncology Source Type: news

RNAi-based screening offers MPM treatment hope
Research using RNA interference-based screening has identified several potential targets for the treatment of malignant pleural mesothelioma. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - January 31, 2014 Category: Cancer & Oncology Source Type: news