Two T1D Patients Achieve Insulin Independence After Stem Cell Transplants
(MedPage Today) -- SAN DIEGO -- Stem cell-derived islet cell therapy continued to show promise for the management of type 1 diabetes (T1D) with severe hypoglycemia, according to results from a small phase I/II clinical trial. All six Part A... (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - June 27, 2023 Category: Primary Care Source Type: news

High-Dose Semaglutide Pill Just as Effective as Wegovy for Weight Loss
(MedPage Today) -- SAN DIEGO -- Once-daily oral semaglutide proved effective for weight loss in people with obesity, according to the phase III OASIS 1 trial. When added to lifestyle intervention over 68 weeks, patients taking 50 mg of oral... (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - June 27, 2023 Category: Primary Care Source Type: news

Novel Triple Agonist Nabs Biggest Weight Loss Yet in Obesity Trial
(MedPage Today) -- SAN DIEGO -- An investigational triple-hormone receptor agonist yielded major weight loss in people with obesity, a phase II trial showed. By 24 weeks, patients on any of the four doses of once-weekly injectable retatrutide... (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - June 26, 2023 Category: Primary Care Source Type: news

Bempedoic Acid Gets 'Huge' Win for Primary Prevention in the Statin-Intolerant
(MedPage Today) -- SAN DIEGO -- Bempedoic acid (Nexletol) prevented cardiovascular events in high-risk, statin-intolerant patients who had not yet had an event, a subgroup analysis from the CLEAR Outcomes trial confirmed. In these patients... (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - June 26, 2023 Category: Primary Care Source Type: news

Malaria Case in Texas; FDA Lays Path for Psychedelic Trials; Incels' Mental Health
(MedPage Today) -- Note that some links may require registration or subscription. Health officials in Texas have confirmed a locally acquired case of malaria. (CBS News) New York Gov. Kathy Hochul (D) signed into law a bill shielding physicians... (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - June 26, 2023 Category: Primary Care Source Type: news

Once-Weekly Insulin Icodec Bests Daily Insulin Options for Type 2 Diabetes
(MedPage Today) -- SAN DIEGO -- Investigational once-weekly insulin icodec outperformed once-daily insulin glargine U100 when it came to glycemic control in type 2 diabetes, the phase IIIa ONWARDS 1 trial found. Over the course of 52 weeks... (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - June 25, 2023 Category: Primary Care Source Type: news

Novel Agent Leads to Fibrosis Improvement in NASH
(MedPage Today) -- VIENNA – Treatment with an investigational FGF21 analogue improved fibrosis in patients with nonalcoholic steatohepatitis (NASH), according to a phase IIb trial. In the ENLIVEN study, patients with biopsy-confirmed NASH... (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - June 24, 2023 Category: Primary Care Source Type: news

What's Changed Since HCA's Takeover of Mission Health?
(MedPage Today) -- Medical professionals and local leaders discussed their views on the state of healthcare in western North Carolina and what may be done to improve it during a panel at the Take Medicine Back virtual summit last week. Specifically... (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - June 20, 2023 Category: Primary Care Source Type: news

No Increase in Major Cardiac Events With Testosterone-Replacement Therapy
(MedPage Today) -- CHICAGO -- Testosterone-replacement therapy was noninferior to placebo in the occurrence of major adverse cardiac events among men with hypogonadism and established or high risk for cardiovascular disease, the randomized TRAVERSE... (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - June 16, 2023 Category: Primary Care Source Type: news

AMA to Amp Up Hospital Consolidation Scrutiny
(MedPage Today) -- CHICAGO -- Physicians pressing for the American Medical Association (AMA) to do more on healthcare consolidation pushed through a resolution to produce in-depth annual reports on the topic that could be used to advocate for... (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - June 15, 2023 Category: Primary Care Source Type: news

Early Alzheimer's Linked to Gut Microbiome Changes
(MedPage Today) -- Changes in gut bacteria were linked with very early Alzheimer's disease, cross-sectional data showed. Gut microbial profiles of cognitively normal people with preclinical Alzheimer's disease -- defined as asymptomatic abnormal... (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - June 14, 2023 Category: Primary Care Source Type: news

FDA OKs Over-the-Counter Gel for Erectile Dysfunction
(MedPage Today) -- The FDA has granted over-the-counter marketing authorization to MED3000 (Eroxon), the first nonprescription topical gel for treating erectile dysfunction (ED), maker Futura Medical announced on Monday. According to the company... (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - June 12, 2023 Category: Primary Care Source Type: news

Decoding the Brain's Decision-Making
(MedPage Today) -- The interplay between the brain's fast and slow, deliberative decision-making systems is complex yet fascinating, shedding light on the cognitive underpinnings of different medical professions, such as emergency department (ED... (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - June 10, 2023 Category: Primary Care Source Type: news

Trial Shows RA Can Be Stopped at Preclinical Stage
(MedPage Today) -- MILAN -- One year of treatment with abatacept (Orencia) kept "preclinical" rheumatoid arthritis (RA) from becoming clinical in most patients showing signs of imminent onset, a researcher reported here. In a phase IIb randomized... (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - June 1, 2023 Category: Primary Care Source Type: news

Getting Inspired to Do More
(MedPage Today) -- Just a quick little column, a reminder that at times, it's nice to be inspired once again. Last week was our sixth annual Primary Care and Hospital Medicine Innovation Symposium, something we started here to provide support... (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - May 31, 2023 Category: Primary Care Source Type: news