The Year SGLT2 Inhibitors Became Full-Fledged Heart Failure Drugs
(MedPage Today) -- Earlier this year, empagliflozin (Jardiance) won FDA approval for a broader indication in heart failure across the spectrum of ejection fraction. As part of our review of the year's top stories, we follow up on what has happened... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - December 27, 2022 Category: Urology & Nephrology Source Type: news
Can Biomarkers Give Early Heads-Up on Immune Checkpoint Inhibitor Myocarditis?
(MedPage Today) -- In the quest to catch myocarditis earlier during immune checkpoint inhibitor (ICI) therapy for cancer, researchers have found a potential role for routinely measured biomarkers.
Of 2,606 consecutive ICI recipients at Michigan... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - December 20, 2022 Category: Urology & Nephrology Source Type: news
Glycemic Control With Insulin Barely Budged Over the Past 30 Years
(MedPage Today) -- Rates of insulin-treated adults achieving glycemic control in the U.S. were stagnant over the past 3 decades, according to National Health and Nutrition Examination Survey data.
Of 2,482 adults ages 20 and older using insulin... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - December 20, 2022 Category: Urology & Nephrology Source Type: news
Metformin Protective Against Joint Replacement in Type 2 Diabetes
(MedPage Today) -- Among people with type 2 diabetes, use of metformin might help to stave off total joint replacement, a population-based cohort study showed.
Among over 40,000 patients, daily metformin was associated with a 30% lower risk for... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - December 19, 2022 Category: Urology & Nephrology Source Type: news
Fecal Transplant Failed to Boost Effects of Bariatric Surgery
(MedPage Today) -- Fecal microbiota transplantation (FMT) had no effect on weight loss, body composition, or metabolic markers in obese individuals who underwent bariatric surgery, said authors of a small clinical trial.
In 41 adults with severe... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - December 16, 2022 Category: Urology & Nephrology Source Type: news
Obesity Absent in One-Fourth of Kids With Type 2 Diabetes
(MedPage Today) -- Among kids with type 2 diabetes (T2D), obesity was common but far from universal in a look at the condition worldwide.
In fact, only 75% of pediatric cases were found to also have obesity, with a rate of 77% at the time of diagnosis... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - December 15, 2022 Category: Urology & Nephrology Source Type: news
No Blaming Common Antihypertensives for Pancreatic Cancer, Study Suggests
(MedPage Today) -- Long-time users of dihydropyridine calcium channel blockers (CCBs) were not at disproportionately high risk of pancreatic cancer, according to a large observational cohort study.
Based on primary care records from the U.K. in... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - December 15, 2022 Category: Urology & Nephrology Source Type: news
Skipping Antiplatelets Altogether Not Such a Bad Idea for Select TAVR Patients
(MedPage Today) -- Following transcatheter aortic valve replacement (TAVR), the optimal antithrombotic regimen for some people may be no antithrombotics at all, according to provocative registry data from Japan.
Compared with the single antiplatelet... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - December 14, 2022 Category: Urology & Nephrology Source Type: news
Omecamtiv Mecarbil Not Ready for Prime Time, FDA Advisors Say
(MedPage Today) -- Omecamtiv mecarbil received a thumbs-down from FDA advisors who complained of its inadequate evidence base during a Cardiovascular and Renal Drugs Advisory Committee meeting on Tuesday.
Members voted 8-3 (with no abstentions... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - December 13, 2022 Category: Urology & Nephrology Source Type: news
Cardiac Contractility Drug Faces Headwinds at FDA Adcomm
(MedPage Today) -- If omecamtiv mecarbil is to gain a heart failure indication, sponsor Cytokinetics has a lot of convincing to do when the FDA Cardiovascular and Renal Drugs Advisory Committee convenes on Tuesday.
FDA advisors will spend the... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - December 12, 2022 Category: Urology & Nephrology Source Type: news
Innovation Is Critical to Stop Disparities in Diabetes Care
(MedPage Today) -- Having spent over 30 years of my career in diabetes, first as a practicing diabetologist and later as a diabetes researcher, I've met many people with diabetes. And while diabetes care has evolved significantly over that time... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - December 10, 2022 Category: Urology & Nephrology Source Type: news
Yoga Flexes Muscle for Those With High Blood Pressure
(MedPage Today) -- Yoga provided extra blood pressure (BP) lowering and other benefits when added to a regular exercise routine, a small pilot trial showed.
At one exercise rehabilitation center, hypertensive patients who were randomized to an... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - December 9, 2022 Category: Urology & Nephrology Source Type: news
Do Kidney Transplant Medications Supplant IBD Drugs?
(MedPage Today) -- ORLANDO -- Many patients who undergo successful renal transplantation and also have Crohn's disease were able to avoid immunomodulating or biologic agents to control their gut disease, researchers found.
Of 37 patients with... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - December 8, 2022 Category: Urology & Nephrology Source Type: news
TAVR at 20: How Much Longer Will Medicare Mandate a Registry?
(MedPage Today) -- As transcatheter aortic valve replacement (TAVR) marked the 20th anniversary this year of the first-in-man use, it also reached its 10th anniversary of coverage by CMS.
But despite the randomized trials proving utility in individuals... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - December 8, 2022 Category: Urology & Nephrology Source Type: news
Type 2 Diabetes Cases Rising in Young Adults Globally
(MedPage Today) -- The global burden of type 2 diabetes among young people significantly rose since 1990, researchers reported.
Drawing on data from 204 countries and territories, the age-standardized incidence of type 2 diabetes from 1990 to... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - December 7, 2022 Category: Urology & Nephrology Source Type: news
