Time to Recognize Cardiovascular-Kidney-Metabolic Syndrome, AHA Says
(MedPage Today) -- With the newly dubbed "cardiovascular-kidney-metabolic (CKM) syndrome," the American Heart Association (AHA) expands concepts of cardiovascular risk, prevention, and management in a framework that touches nearly every major organ... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - October 9, 2023 Category: Urology & Nephrology Source Type: news

Smoking-Related Metabolic Changes Partly Drive Type 2 Diabetes Risk
(MedPage Today) -- HAMBURG, Germany -- Smokers were more likely to have a specific metabolic signature that mediated their risk for developing type 2 diabetes, a researcher reported here. In a study of nearly 94,000 people in the U.K. Biobank... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - October 6, 2023 Category: Urology & Nephrology Source Type: news

Repeat Tests for Inflammation Aid Prognosis After Acute Heart Failure
(MedPage Today) -- Longitudinal high-sensitivity C-reactive protein (hsCRP) testing helped identify people with the worst outcomes following hospitalization for acute heart failure, researchers found from a Chinese cohort study. Long-term cumulative... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - October 2, 2023 Category: Urology & Nephrology Source Type: news

FDA Panel: All Thumbs Down for GLP-1 Agonist Implant for Diabetes
(MedPage Today) -- Not a single FDA advisory committee member said the benefits of an implant that delivers a GLP-1 receptor agonist for type 2 diabetes outweigh its risks. In a unanimous 19-0 vote on Thursday, the Endocrinologic and Metabolic... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - September 22, 2023 Category: Urology & Nephrology Source Type: news

FDA Panel Reluctantly Backs Patisiran for ATTR Cardiomyopathy
(MedPage Today) -- FDA advisors conceded on Wednesday that the benefit-risk balance of patisiran (Onpattro) technically checks out in wild-type or hereditary transthyretin amyloid cardiomyopathy (ATTR-CM, also known as cardiac ATTR amyloidosis... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - September 14, 2023 Category: Urology & Nephrology Source Type: news

Mask Attack Leaves Actor Blind; Diabetes Risk in Night Owls; U.S. Blood Shortage
(MedPage Today) -- Note that some links may require registration or subscription. Former actor Will Keenan said he was left potentially blind in one eye after being attacked for wearing a face mask, leaving him with a detached retina. (Newsweek... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - September 12, 2023 Category: Urology & Nephrology Source Type: news

'Big Win' for Anti-Obesity Medication in Heart Failure
(MedPage Today) -- In this video, Harlan Krumholz, MD, SM, of the Yale School of Medicine and Yale New Haven Hospital in Connecticut, discusses a randomized trial that showed semaglutide (Wegovy) led to improvements in symptoms and weight for heart... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - August 29, 2023 Category: Urology & Nephrology Source Type: news

Compound in Beetroot Juice Fends Off Contrast-Induced AKI
(MedPage Today) -- AMSTERDAM -- An oral nitrate pill reduced contrast-induced acute kidney injury (AKI) when given to heart attack patients before they underwent invasive coronary angiography, the single-center NITRATE-CIN trial showed. In people... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - August 29, 2023 Category: Urology & Nephrology Source Type: news

CRT-D Upgrade Suits Patients With Pacing-Related Heart Failure
(MedPage Today) -- AMSTERDAM -- A cardiac resynchronization therapy (CRT) upgrade produced solid clinical benefit for patients with pacing-induced heart failure with reduced ejection fraction (HFrEF), the small BUDAPEST CRT Upgrade randomized... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - August 27, 2023 Category: Urology & Nephrology Source Type: news

Iron Infusions Narrowly Miss the Mark for Clinical Benefit in Heart Failure
(MedPage Today) -- AMSTERDAM -- Ferric carboxymaltose (FCM) did not go so far as to improve hard outcomes in people with heart failure with reduced ejection fraction (HFrEF) and iron deficiency in the well-powered HEART-FID trial, and it is questionable... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - August 26, 2023 Category: Urology & Nephrology Source Type: news

SGLT2 Inhibitors, Rapid Titration, IV Iron Get a Boost in New European HF Guideline
(MedPage Today) -- AMSTERDAM -- SGLT2 inhibitor therapy and other innovations in heart failure (HF) treatment were among the highlights of the updated European guidelines presented here at the European Society of Cardiology Congress and published... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - August 25, 2023 Category: Urology & Nephrology Source Type: news

Wegovy Reduces Heavy Symptom Burden of Obesity-Related Heart Failure
(MedPage Today) -- AMSTERDAM -- Semaglutide 2.4 mg (Wegovy) led to clinically meaningful reductions in symptoms and weight among patients with obesity and heart failure with preserved ejection fraction (HFpEF), the STEP-HFpEF trial showed. While... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - August 25, 2023 Category: Urology & Nephrology Source Type: news

Medtronic's Renal Denervation System for Hypertension Splits FDA Panel
(MedPage Today) -- A radiofrequency-based renal denervation system for uncontrolled hypertension got a cool reception from FDA advisors who nevertheless left the door open for regulatory approval. On Wednesday, the FDA's Circulatory System Devices... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - August 24, 2023 Category: Urology & Nephrology Source Type: news

In a Pig's Eye: Xenograft Kidneys for the Dead
(MedPage Today) -- Doctors at NYU Langone recently revealed they had transplanted a genetically altered pig kidney into a brain-dead body, presumably to demonstrate that such a thing might be possible in a living body. The report of the story claims... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - August 23, 2023 Category: Urology & Nephrology Source Type: news

Unexpected Bonus Benefit With Lifestyle Intervention in Type 2 Diabetes
(MedPage Today) -- An intensive lifestyle intervention (ILI) designed to prevent the progression and complications of type 2 diabetes was associated with boosted employment rates, according to an ancillary study of the Look AHEAD (Action for Health... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - August 14, 2023 Category: Urology & Nephrology Source Type: news