Changing the Surgical Paradigm in Oligometastatic NSCLC
(MedPage Today) -- Patients with single-site synchronous oligometastatic non-small cell lung cancer (NSCLC) had better overall survival (OS) when they received surgery for their primary tumor, a retrospective review of nationwide data showed.... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - February 23, 2024 Category: Hematology Source Type: news

Transforming Shots Into Pills; 'Tip of the Iceberg' for TILs? Food Additives Warning
(MedPage Today) -- A California startup has the lofty goal of transforming blockbuster injectable and infusional drugs into pills. (Endpoints News) Johnson & Johnson announced FDA approval of a less frequent dosing regimen for teclistamab... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - February 23, 2024 Category: Hematology Source Type: news

Cabozantinib Plus Atezolizumab Improves PFS in Metastatic CRPC
(MedPage Today) -- In patients with metastatic castration-resistant prostate cancer (mCRPC) whose disease progressed on a novel hormonal therapy, the combination of cabozantinib (Cabometyx) plus atezolizumab (Tecentriq) improved radiographic progression... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - February 22, 2024 Category: Hematology Source Type: news

Elotuzumab Misses Mark Again as Frontline Treatment for Multiple Myeloma
(MedPage Today) -- Elotuzumab (Empliciti) failed for a third time to improve progression-free survival (PFS) in newly diagnosed multiple myeloma when added to standard therapy, a large randomized trial showed. After 4 years of follow-up, neither... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - February 21, 2024 Category: Hematology Source Type: news

Annual Breast Cancer Screening Starting at Age 40 Best, Modeling Study Says
(MedPage Today) -- Annual breast cancer screening at ages 40 to 79 resulted in the greatest reduction in mortality, according to a study comparing various screening scenarios. Using Cancer Intervention and Surveillance Modeling Network (CISNET... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - February 20, 2024 Category: Hematology Source Type: news

Radioligand Therapy Continues to Show Promise for Metastatic CRPC
(MedPage Today) -- Radioligand therapy (RLT) with actinium-225 targeting prostate-specific membrane antigen (225Ac-PSMA) had a "substantial antitumor effect" in heavily pretreated metastatic castration-resistant prostate cancer (mCRPC), a large... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - February 17, 2024 Category: Hematology Source Type: news

Arginine Starvation Boosts OS in Mesothelioma
(MedPage Today) -- First-line chemotherapy plus an investigational arginine-depleting agent improved survival in nonepithelioid pleural mesothelioma compared with chemotherapy alone, a randomized trial showed. For the study's primary endpoint... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - February 16, 2024 Category: Hematology Source Type: news

Cancer Patients Caught in the Crosshairs of Hospital Consolidation
(MedPage Today) -- With patient access and affordability at stake, lawmakers are turning their attention to alleged hospital monopolies and the increasingly alarming rate of hospital consolidation -- and not a moment too soon. As hospitals and... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - February 16, 2024 Category: Hematology Source Type: news

Perioperative Tislelizumab Demonstrates Survival Benefit in NSCLC
(MedPage Today) -- Adding tislelizumab to neoadjuvant chemotherapy followed by adjuvant use of the investigational PD-1 inhibitor improved event-free survival (EFS) in resectable non-small cell lung cancer (NSCLC), a phase III trial from China... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - February 16, 2024 Category: Hematology Source Type: news

Rush to Publish? Medicare Drug Plan Lawsuit Quashed; Activity Curbs Cancer Pain
(MedPage Today) -- The quiet retraction of a journal article on stomach cancer with "suspicious data" has shone a light on publishers' desire "to put out huge volumes of studies while avoiding the reputational damage of retracting them publicly... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - February 16, 2024 Category: Hematology Source Type: news

More Data Support Olaparib-Abiraterone in BRCA-Mutant Prostate Cancer
(MedPage Today) -- Combining olaparib (Lynparza) with abiraterone acetate (Zytiga) as first-line therapy for biomarker-selected patients with metastatic castration-resistant prostate cancer significantly improved progression-free survival (PFS... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - February 15, 2024 Category: Hematology Source Type: news

Oldest Patient 'Cured' of HIV Still in Remission 5 Years After Transplant for AML
(MedPage Today) -- A 68-year-old man with HIV-1 who underwent hematopoietic cell transplant (HCT) for acute myelogenous leukemia 5 years ago has been free of HIV infection for 35 months after stopping antiretroviral treatment (ART), according to... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - February 15, 2024 Category: Hematology Source Type: news

FLT3 Inhibitor Highly Active in Newly Diagnosed Acute Myeloid Leukemia
(MedPage Today) -- Patients with newly diagnosed FLT3-mutated acute myeloid leukemia (AML) had a high response rate and prolonged event-free survival (EFS) following treatment with an investigational FLT3 inhibitor and chemotherapy, a preliminary... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - February 13, 2024 Category: Hematology Source Type: news

Oncologists Risk Self-Referral Violations Over Medicare Mail-Order Drug Rule
(MedPage Today) -- A new interpretation of a decades-old law could put community oncology practices in the crosshairs of regulators who monitor and enforce provisions against self-referral and add a barrier to patient access. Enacted by Congress... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - February 13, 2024 Category: Hematology Source Type: news

No Relief From Drug Shortages; New Lymphedema Guideline; A 'Good' Patient No More
(MedPage Today) -- Drug shortages persist, as the FDA faces multiple challenges in its oversight of COVID-19-related production disruptions at foreign manufacturing facilities. (BioSpace) A wrongful death lawsuit filed in Florida alleges that... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - February 10, 2024 Category: Hematology Source Type: news