Low-Dose RT Boost Wins Support for Young Patients With Early Breast Cancer
(MedPage Today) -- A low-dose radiotherapy (RT) boost to the tumor bed provided adequate control of breast cancer recurrence in younger patients with better cosmetic results as compared with a high-dose boost, long-term follow-up from a randomized... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 21, 2024 Category: Hematology Source Type: news

Lenvatinib-Pembrolizumab Combo Misses on Survival in Endometrial Cancer Trial
(MedPage Today) -- SAN DIEGO -- A combination of lenvatinib (Lenvima) and pembrolizumab (Keytruda) failed to meet survival endpoints compared with chemotherapy as first-line therapy for patients with advanced or recurrent endometrial cancer... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 20, 2024 Category: Hematology Source Type: news

Mutation Linked to Increased Risk of Prostate Cancer Mortality
(MedPage Today) -- The risk of dying of prostate cancer doubled in the presence of a genetic mutation affecting testosterone production, a large prospective cohort study showed. The 5-year risk of prostate cancer-specific mortality (PCSM) increased... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 20, 2024 Category: Hematology Source Type: news

Long-Term Breast Cancer Risk in Hodgkin Lymphoma Survivors Treated With Doxorubicin
(MedPage Today) -- A common chemotherapy drug used to treat Hodgkin lymphoma conferred a significantly increased risk of breast cancer among women treated during adolescence and adulthood, a large retrospective study showed. Women who received... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 20, 2024 Category: Hematology Source Type: news

Rucaparib Maintenance Boosts PFS in Metastatic, Recurrent Endometrial Cancer
(MedPage Today) -- SAN DIEGO -- Rucaparib (Rubraca) maintenance after first- or second-line chemotherapy improved progression-free survival (PFS) in patients with metastatic or recurrent endometrial cancer, a small phase II randomized trial showed... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 19, 2024 Category: Hematology Source Type: news

Safety of Less-Radical Surgery for Early Cervical Cancer Gathers More Evidence
(MedPage Today) -- SAN DIEGO -- The safety of non-radical approaches to surgery in early, low-risk cervical cancer gained additional support from a new prospective study, though fertility preservation with cone biopsy also came with some cases... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 19, 2024 Category: Hematology Source Type: news

Laparoscopy Quickly Abandoned in Early Cervical Cancer After LACC Results
(MedPage Today) -- SAN DIEGO -- Oncologic surgeons rapidly abandoned minimally invasive surgery (MIS) for early-stage cervical cancer in the wake of a startling 2018 study that warned of the dangers of the approach for this patient population... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 18, 2024 Category: Hematology Source Type: news

Novel Drug-Device Shows Efficacy for High-Grade Cervical Lesions
(MedPage Today) -- SAN DIEGO -- A novel, noninvasive, photodynamic drug-device combination was efficacious and safe for patients with cervical histologic high-grade squamous intraepithelial lesions (HSIL), a randomized phase III trial showed... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 18, 2024 Category: Hematology Source Type: news

Immune Checkpoint Inhibitor-Chemo Combo Boosts OS in Advanced Endometrial Cancer
(MedPage Today) -- SAN DIEGO -- The addition of an immune checkpoint inhibitor (ICI) to chemotherapy up front improved overall survival (OS) in patients with advanced or recurrent endometrial cancer, regardless of mismatch repair (MMR) status... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 18, 2024 Category: Hematology Source Type: news

Raludotatug Deruxtecan Promising in Platinum-Resistant Advanced Ovarian Cancer
(MedPage Today) -- SAN DIEGO -- Treatment with raludotatug deruxtecan (R-DXd) led to an "exciting" response rate among patients with heavily pretreated, platinum-resistant advanced ovarian cancer, according to an early-phase trial. In a subgroup... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 17, 2024 Category: Hematology Source Type: news

Getting Prostate Cancer Drugs Sooner; Limiting Toxic Emissions; FTC Sues 'Charity'
(MedPage Today) -- Progression-free survival reasonably predicts overall survival in advanced prostate cancer and could bring new therapies to patients about 2 years faster if used as the primary endpoint in clinical studies. (University College... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 14, 2024 Category: Hematology Source Type: news

Rheumatologist Found Dead; How COVID Changed Lives; Olivia Munn's Breast Cancer
(MedPage Today) -- Note that some links may require registration or subscription. A Connecticut rheumatologist was found dead after his arrest in a child sex abuse investigation. (WTNH) Multiple class action lawsuits may join forces accusing... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 14, 2024 Category: Hematology Source Type: news

Novel CAR-T for Glioblastoma Induced 'Dramatic' Responses in Early Trial
(MedPage Today) -- A new approach to chimeric antigen receptor (CAR) T-cell therapy showed promise in treating recurrent glioblastoma, according to a small phase I study. In the first-in-human trial, three patients with recurrent glioblastoma... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 14, 2024 Category: Hematology Source Type: news

Sickle Cell Pain Hospitalizations Rose After CDC's Opioid Recs
(MedPage Today) -- A downward trend in opioid prescribing practices for patients with sickle cell disease (SCD) followed the CDC's 2016 opioid guidelines for chronic pain, an analysis of claims data showed, but so did a steady increase in pain... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 11, 2024 Category: Hematology Source Type: news

First-Line Nivolumab Plus Chemo Approved for Bladder Cancer
(MedPage Today) -- The FDA approved the PD-1 immune checkpoint inhibitor nivolumab (Opdivo) in combination with cisplatin and gemcitabine for the first-line treatment of adults with unresectable or metastatic urothelial carcinoma, the agency announced... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 7, 2024 Category: Hematology Source Type: news