High Response Rate in R/R Multiple Myeloma With Bispecific Antibody
(MedPage Today) -- SAN DIEGO -- More than 70% of patients with heavily pretreated multiple myeloma responded to an investigational bispecific antibody targeting B-cell maturation antigen (BCMA) and CD3, results from a prospective trial showed... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - April 8, 2024 Category: Hematology Source Type: news

Most Cancer Drugs Granted Accelerated Approval Fail Confirmatory Trials
(MedPage Today) -- SAN DIEGO -- Most cancer drugs granted accelerated approval by the FDA have not demonstrated a benefit in overall survival (OS) or quality of life within 5 years, according to a cohort study presented here. Of 46 cancer drug... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - April 8, 2024 Category: Hematology Source Type: news

PSA and Biomarker Testing Plus MRI Appears to Improve Prostate Cancer Screening
(MedPage Today) -- A single round of prostate cancer screening that included a prostate-specific antigen (PSA) test, a kallikrein panel, and an MRI detected one additional high-grade cancer per 196 men and one low-grade cancer per 909 men, according... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - April 6, 2024 Category: Hematology Source Type: news

Cancer 'Tidal Wave' Forecast; Not Decaf, Too! Cautionary Tales of Cancer, Cannabis
(MedPage Today) -- If projected changes in population growth and aging hold, a "tidal wave" of cancer cases could increase the worldwide prevalence by 77% over the next 25 years. (CA: A Cancer Journal for Clinicians) A cancer "previvor" clinic... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - April 5, 2024 Category: Hematology Source Type: news

Factor D Inhibitor Wins Approval for PNH With Extravascular Hemolysis
(MedPage Today) -- The FDA approved the oral factor D inhibitor danicopan (Voydeya) as an add-on therapy to treat extravascular hemolysis in adults with paroxysmal nocturnal hemoglobinuria (PNH), AstraZeneca announced. The approval specifies use... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - April 4, 2024 Category: Hematology Source Type: news

Evidence Strengthens for De-Escalating Axillary Surgery in Breast Cancer
(MedPage Today) -- The concept of skipping axillary lymph node dissection (ALND) in some patients with breast cancer was supported by a European noninferiority trial. Among patients with early-stage, node-negative breast cancer and one or two... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - April 3, 2024 Category: Hematology Source Type: news

Some Cancer Patients Can Find It Hard to Tell Family and Friends
(MedPage Today) -- Ever since Anthony Bridges found out he had prostate cancer 6 years ago, he hasn't stopped talking about it. He told his Facebook friends immediately. Now, the 68-year-old man from Georgia spends time working with others to... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 31, 2024 Category: Hematology Source Type: news

The Cancer Journey Is Not Unique to the Royals
(MedPage Today) -- The royal family in the U.K. has had a rough start to 2024. The culprit is cancer. In January, news broke that Sarah Ferguson, the Duchess of York, had been diagnosed with malignant skin cancer during her breast cancer treatment... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 30, 2024 Category: Hematology Source Type: news

Chemo and Heart Disease; Flawed Lung Cancer Screening; New Vax Recommendations
(MedPage Today) -- An author shares his own story about the "pay me now or pay me later" relationship between cancer chemotherapy and heart disease. (Washington Post) Three pending cases before the U.S. Supreme Court have the potential to reshape... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 29, 2024 Category: Hematology Source Type: news

PD-1 Inhibitor Plus Chemotherapy Shows Promising Activity in Rare Lymphoma
(MedPage Today) -- An investigational PD-1 inhibitor combined with chemotherapy showed impressive activity in treatment-naive patients with advanced extranodal natural killer/T-cell lymphoma (ENKTL), according to results from a small Chinese single... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 28, 2024 Category: Hematology Source Type: news

Once-Rejected Drug Now FDA Approved for CKD-Related Anemia
(MedPage Today) -- The FDA approved vadadustat (Vafseo) for chronic kidney disease (CKD)-related anemia in adults who have been on dialysis for at least 3 months, developer Akebia Therapeutics announced on Wednesday. "Patients receiving maintenance... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 28, 2024 Category: Hematology Source Type: news

'Excellent' Outcomes After Complete Response in Lymph Node-Positive Breast Cancer
(MedPage Today) -- Patients with early lymph node-positive breast cancer and pathologic complete response (pCR) after neoadjuvant therapy had similar long-term recurrence rates and survival regardless of the type of adjuvant therapy they received... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 27, 2024 Category: Hematology Source Type: news

Breastfeeding Tied to Reduced Childhood Leukemia Risk
(MedPage Today) -- Longer duration of exclusive breastfeeding was associated with a reduced risk of childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL), according to results from a Danish population-based cohort study. Compared with... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 27, 2024 Category: Hematology Source Type: news

Overdosing on Chemo: A Common Gene Test Could Save Hundreds of Lives Each Year
(MedPage Today) -- One January morning in 2021, Carol Rosen took a standard treatment for metastatic breast cancer. Three gruesome weeks later, she died in excruciating pain from the very drug meant to prolong her life. Rosen, a 70-year-old retired... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 26, 2024 Category: Hematology Source Type: news

Big Drop in Rate of Ipsilateral Breast Cancer After DCIS
(MedPage Today) -- The incidence of invasive breast cancer after conservative treatment for ductal carcinoma in situ (DCIS) decreased by more than 50% over the past 30 years, data from a Dutch cancer registry showed. Among 19,000 patients who... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 26, 2024 Category: Hematology Source Type: news