Is Omitting Radiation Therapy in Low-Risk Breast Cancer a Good IDEA?
(MedPage Today) -- SAN ANTONIO -- Postmenopausal women with genomically low-risk early hormone receptor (HR)-positive breast cancer had a low risk of recurrence with endocrine therapy alone after lumpectomy, a randomized trial showed.
The 5... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 8, 2023 Category: Hematology Source Type: news
Study Supports ADC as a New Option for Endocrine-Resistant Metastatic Breast Cancer
(MedPage Today) -- SAN ANTONIO -- The investigational Trop2-directed antibody-drug conjugate (ADC) datopotamab deruxtecan (Dato-DXd) continued to best chemotherapy in new results from the phase III randomized TROPION-Breast01 trial.
Looking... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 8, 2023 Category: Hematology Source Type: news
Maintenance Pembrolizumab-Olaparib Fails to Boost Survival in TNBC
(MedPage Today) -- SAN ANTONIO -- A maintenance strategy involving checkpoint blockade and a PARP inhibitor after first-line therapy did not improve survival outcomes in unselected patients with triple-negative breast cancer (TNBC), though was... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 8, 2023 Category: Hematology Source Type: news
Detecting Ovarian Cancer Early; Allergy Med for NSCLC? Bad News for Anti-TIGIT Drug
(MedPage Today) -- It may be possible to detect ovarian cancer years in advance of actual symptom onset based on the molecular and genetic analysis of cells taken from routine Pap tests. (Science Translational Medicine)
A six-patient clinical... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 7, 2023 Category: Hematology Source Type: news
Doing More With Less Blood
(MedPage Today) -- In 1988, I was a third-year anesthesia resident on a casual weekend bike ride with my fiancé and two friends, on the scenic Maryland back roads. The next thing I remember is waking up in the recovery room after a head-on... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 7, 2023 Category: Hematology Source Type: news
The Treatment Landscape for Cervical Cancer Has Changed
(MedPage Today) -- MedPage Today brought together three expert leaders in the field of gynecologic cancers -- moderator Susana Campos, MD, from the Dana-Farber Cancer Institute in Boston, is joined by Richard Penson, MBBS, of Mass General Cancer... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 7, 2023 Category: Hematology Source Type: news
No Benefit to Adjuvant-Only Immunotherapy in Early TNBC
(MedPage Today) -- SAN ANTONIO -- Adjuvant-only immunotherapy with atezolizumab (Tecentriq) added to a standard chemotherapy backbone failed to improve invasive disease-free survival (iDFS) compared with chemotherapy alone in patients with early... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 7, 2023 Category: Hematology Source Type: news
De-Escalating Breast Cancer Treatment Feasible After Response to Neoadjuvant Chemo
(MedPage Today) -- SAN ANTONIO -- Omitting regional nodal irradiation (RNI) did not increase the risk of disease progression or death in patients whose breast cancer changed from lymph node-positive to lymph node-negative after neoadjuvant chemotherapy... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 7, 2023 Category: Hematology Source Type: news
Tucatinib Regimen Boosts PFS in Advanced HER2-Positive Breast Cancer
(MedPage Today) -- SAN ANTONIO -- Adding tucatinib (Tukysa) to trastuzumab emtansine (T-DM1; Kadcyla) reduced the risk of disease progression or death by 24% in previously treated HER2-positive breast cancer patients with locally advanced unresectable... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 7, 2023 Category: Hematology Source Type: news
Rituximab Maintenance Boosts Survival for Older Adults With MRD-Negative MCL
(MedPage Today) -- Maintenance therapy with rituximab yielded better survival outcomes for older patients with minimal residual disease (MRD) negativity after induction therapy for mantle cell lymphoma (MCL), results from the European Mantle Cell... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 5, 2023 Category: Hematology Source Type: news
First Gene Therapy for Non-Muscle-Invasive Bladder Cancer Offers Durable Response
(MedPage Today) -- WASHINGTON -- The gene therapy nadofaragene firadenovec (Adstiladrin) continued to demonstrate clinical activity in patients with high-risk bladder cancer, researchers reported.
The long-term follow-up data came from a phase... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 4, 2023 Category: Hematology Source Type: news
Novel Therapy Reduced Transfusion Dependence in Lower-Risk MDS
(MedPage Today) -- Patients with lower-risk myelodysplastic syndromes (MDS) who relapsed or were refractory to standard treatment achieved improved rates of red blood cell (RBC) transfusion independence with an investigational, first-in-class telomerase... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 4, 2023 Category: Hematology Source Type: news
Non-Covalent BTK Inhibitor Approved for CLL
(MedPage Today) -- The FDA expanded the label of pirtobrutinib (Jaypirca) to include the treatment of chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL) following two prior lines of therapy, the agency announced on Friday.
An... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 4, 2023 Category: Hematology Source Type: news
Charting the Course: From Young Adult Leukemia Patient to Oncologist
(MedPage Today) -- "Would you like to have a bone marrow biopsy today or tomorrow?" These are the only words I remember coming from the oncologist who I had just met in the emergency department (ED).
I was in my second year of medical school and... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 3, 2023 Category: Hematology Source Type: news
Let's Talk Drug Prices; Restoring the Sense of Touch; Learning From Tumors in a Dish
(MedPage Today) -- Sen. Bernie Sanders (I-Vt.) has invited CEOs of Johnson & Johnson, Merck, and Bristol Myers Squibb to testify next month at a hearing on drug pricing, specifically to discuss why the U.S. pays so much more than other countries... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 2, 2023 Category: Hematology Source Type: news
