Frontline Venetoclax-Ibrutinib for CLL Boosts Survival in Fit Patients
(MedPage Today) -- SAN DIEGO -- A time-limited, targeted combination significantly improved survival compared with chemoimmunotherapy in fit chronic lymphocytic leukemia (CLL) patients who met criteria for starting treatment, findings from the... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 10, 2023 Category: Hematology Source Type: news

'New Gold Standard' for Previously Untreated CLL
(MedPage Today) -- SAN DIEGO -- A time-limited, targeted combination significantly improved survival compared with chemoimmunotherapy in fit chronic lymphocytic leukemia (CLL) patients who met criteria for starting treatment, findings from the... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 10, 2023 Category: Hematology Source Type: news

Grappling With Our Deadliest Cancer
(MedPage Today) -- Each year, we lose 127,000 Americans to lung cancer. That's nearly the equivalent of a commercial airliner packed with passengers falling out of the sky every other day, making lung cancer "by far the leading cause of cancer... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 10, 2023 Category: Hematology Source Type: news

Emicizumab Safe, Effective, in Infants With Hemophilia A
(MedPage Today) -- SAN DIEGO -- Administering emicizumab (Hemlibra) to previously untreated or minimally treated infants with severe hemophilia A without factor VIII inhibitors is effective and safe, according to results from research presented... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 10, 2023 Category: Hematology Source Type: news

Add-On Inavolisib Ups PFS in PIK3CA-Mutated Breast Cancer
(MedPage Today) -- SAN ANTONIO -- The addition of inavolisib to palbociclib (Ibrance) plus fulvestrant (Faslodex) boosted progression-free survival (PFS) in patients with recurrent PIK3CA-mutated HR-positive, HER2-negative advanced breast cancer... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 10, 2023 Category: Hematology Source Type: news

Lovo-Cel 'Life-Changing, Transformative' in Sickle Cell Disease
(MedPage Today) -- SAN DIEGO -- A one-time treatment with lovotibeglogene autotemcel (Lyfgenia, lovo-cel) achieved near complete resolution of severe pain crises in patients with sickle cell disease (SCD) in an analysis presented here. Of 34... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 10, 2023 Category: Hematology Source Type: news

Completely Oral Regimen Effective, Feasible in APL
(MedPage Today) -- SAN DIEGO -- An all-oral regimen for newly diagnosed acute promyelocytic leukemia (APL) proved "highly effective and safe," with most patients avoiding chemotherapy altogether, a researcher reported here. In a multicenter... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 10, 2023 Category: Hematology Source Type: news

Bilateral Mastectomy Not Tied to Better Survival in BRCA1-Positive Breast Cancer
(MedPage Today) -- SAN ANTONIO -- Bilateral mastectomy as initial treatment for women with breast cancer and a pathogenic BRCA1 variant was not linked to better survival, according to an international analysis. Compared with breast-conserving... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 9, 2023 Category: Hematology Source Type: news

AI and Breast Cancer Screening; Cancer After Treatment for Sickle Cell
(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 9, 2023 Category: Hematology Source Type: news

Is Omitting Radiation Therapy in Low-Risk Breast Cancer a Good IDEA?
(MedPage Today) -- SAN ANTONIO -- Postmenopausal women with genomically low-risk early hormone receptor (HR)-positive breast cancer had a low risk of recurrence with endocrine therapy alone after lumpectomy, a randomized trial showed. The 5... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 8, 2023 Category: Hematology Source Type: news

Study Supports ADC as a New Option for Endocrine-Resistant Metastatic Breast Cancer
(MedPage Today) -- SAN ANTONIO -- The investigational Trop2-directed antibody-drug conjugate (ADC) datopotamab deruxtecan (Dato-DXd) continued to best chemotherapy in new results from the phase III randomized TROPION-Breast01 trial. Looking... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 8, 2023 Category: Hematology Source Type: news

Maintenance Pembrolizumab-Olaparib Fails to Boost Survival in TNBC
(MedPage Today) -- SAN ANTONIO -- A maintenance strategy involving checkpoint blockade and a PARP inhibitor after first-line therapy did not improve survival outcomes in unselected patients with triple-negative breast cancer (TNBC), though was... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 8, 2023 Category: Hematology Source Type: news

Detecting Ovarian Cancer Early; Allergy Med for NSCLC? Bad News for Anti-TIGIT Drug
(MedPage Today) -- It may be possible to detect ovarian cancer years in advance of actual symptom onset based on the molecular and genetic analysis of cells taken from routine Pap tests. (Science Translational Medicine) A six-patient clinical... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 7, 2023 Category: Hematology Source Type: news

Doing More With Less Blood
(MedPage Today) -- In 1988, I was a third-year anesthesia resident on a casual weekend bike ride with my fiancé and two friends, on the scenic Maryland back roads. The next thing I remember is waking up in the recovery room after a head-on... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 7, 2023 Category: Hematology Source Type: news

The Treatment Landscape for Cervical Cancer Has Changed
(MedPage Today) -- MedPage Today brought together three expert leaders in the field of gynecologic cancers -- moderator Susana Campos, MD, from the Dana-Farber Cancer Institute in Boston, is joined by Richard Penson, MBBS, of Mass General Cancer... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 7, 2023 Category: Hematology Source Type: news