Researchers Identify New Genetic And Epigenetic Contributors To Diabetes - 1/6/15
An analysis of the genomes and epigenomes of lean and obese mice and humans has turned up a wealth of clues about how genes and the environment conspire to trigger diabetes, Johns Hopkins researchers say. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - January 6, 2015 Category: Research Source Type: news

Johns Hopkins Medicine Charts Successful Path for Improving Patient Safety at Large Health Systems - 1/5/15
Clear goals, strong leadership and infrastructure, staff engagement, and transparent reporting methods are key for complex health care systems seeking to establish successful patient safety performance improvements, according to a Johns Hopkins study published in the journal Academic Medicine in December. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - January 5, 2015 Category: Research Source Type: news

‘Crispr’ Science: Newer Genome Editing Tool Shows Promise in Engineering Human Stem Cells - 1/5/15
A powerful “genome editing” technology known as CRISPR has been used by researchers since 2012 to trim, disrupt, replace or add to sequences of an organism’s DNA. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - January 5, 2015 Category: Research Source Type: news

James Segars Named Professor and Director of New Research Division of Gynecology and Obstetrics Department - 1/5/15
Johns Hopkins University School of Medicine has named James H. Segars, M.D., the inaugural professor and director of Reproductive Science and Women’s Health Research, a newly established division of the Department of Gynecology and Obstetrics. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - January 5, 2015 Category: Research Source Type: news

New Treatment Strategy Allows Lower Doses of Toxic Tuberculosis Drug Without Compromising Potency - 12/30/14
Already known to cut proteins, the enzyme SPPL3 turns out to have additional talents, according to a new study from Johns Hopkins. In its newly discovered role, SPPL3 works without cutting proteins to activate T cells, the immune system’s foot soldiers. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - December 30, 2014 Category: Research Source Type: news

Enzyme's Alter Ego Helps Activate the Immune System - 12/29/14
Already known to cut proteins, the enzyme SPPL3 turns out to have additional talents, according to a new study from Johns Hopkins. In its newly discovered role, SPPL3 works without cutting proteins to activate T cells, the immune system’s foot soldiers. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - December 29, 2014 Category: Research Source Type: news

Lack of Standards for Public Reports Can Misguide, Rather Than Inform, Patients and Health Care Providers - 12/24/14
A lack of standards for public performance reports can misinform patients and health care providers, say experts from the Johns Hopkins Armstrong Institute for Patient Safety and Quality and the Northeastern University’s Center for Health Policy and Healthcare Research. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - December 24, 2014 Category: Research Source Type: news

Locking Mechanism Found for 'Scissors' that Cut DNA - 12/24/14
Researchers at Johns Hopkins have discovered what keeps an enzyme from becoming overzealous in its clipping of DNA. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - December 24, 2014 Category: Research Source Type: news

Lightweight Skeletons Of Modern Humans Have Recent Origin - 12/22/14
New research shows that modern human skeletons evolved into their lightly built form only relatively recently — after the start of the Holocene about 12,000 years ago, and even more recently in some human populations. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - December 22, 2014 Category: Research Source Type: news

New Data: Risk for Leukemia After Treatment for Early Stage Breast Cancer Higher Than Reported - 12/22/14
The risk of developing leukemia after radiation therapy or chemotherapy for early stage breast cancer remains very small, but it is twice as high as previously reported, according to results of a new study led by researchers at the Johns Hopkins Kimmel Cancer Center. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - December 22, 2014 Category: Research Source Type: news

Allegheny Health Network, Highmark Health and Johns Hopkins Medicine Announce Collaboration - 12/22/14
Officials at Highmark Health, Allegheny Health Network, Highmark Inc. and Johns Hopkins Medicine today announced the signing of a new master collaboration agreement that will complement the formal oncology collaboration that began earlier this year. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - December 22, 2014 Category: Research Source Type: news

Use with Caution: High Doses of Vancomycin Fuel Risk of Kidney Damage in Children - 12/22/14
Results of a small Johns Hopkins Children’s Center study show that hospitalized children given high-dose IV infusions of the antibiotic vancomycin to treat drug-resistant bacterial infections face an increased risk for kidney damage — an often reversible but sometimes serious complication. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - December 22, 2014 Category: Research Source Type: news

Sugar Coated Microcapsule Eliminates Toxic Punch of Experimental Anti-Cancer Drug - 12/17/14
Johns Hopkins researchers have developed a sugar-based molecular microcapsule that eliminates the toxicity of an anticancer agent developed a decade ago at Johns Hopkins, called 3-bromopyruvate, or 3BrPA, in studies of mice with implants of human pancreatic cancer tissue. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - December 17, 2014 Category: Research Source Type: news

Mobilization of Recovered Ebola Patients Could Provide Desperately Needed Manpower in Fight to Curb Epidemic - 12/17/14
As foreign and domestic health care workers in West Africa fight to contain the deadliest Ebola virus disease outbreak in history, a group of disaster response and modeling experts from Johns Hopkins say a potential pool of manpower to help care for patients with Ebola is being overlooked and should be tapped quickly: people who have survived and recovered from Ebola virus infection. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - December 17, 2014 Category: Research Source Type: news

Multiple Allergic Reactions Traced To Single Protein - 12/17/14
Johns Hopkins and University of Alberta researchers have identified a single protein as the root of painful and dangerous allergic reactions to a range of medications and other substances. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - December 17, 2014 Category: Research Source Type: news