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Wayne State receives NSF award to study how airborne viruses navigate through mucus
(Wayne State University - Office of the Vice President for Research) A research team at Wayne State University led by Ashis Mukhopadhyay, Ph.D., associate professor of physics and astronomy in the College of Liberal Arts and Sciences, received a three-year, $326,226 grant from the National Science Foundation to investigate fundamental issues related to the passage of viruses through the mucus barrier. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 28, 2021 Category: Infectious Diseases Source Type: news

Escape room simulation promotes infection control adherence at the temple VA
(Association for Professionals in Infection Control) Designed initially for entertainment purposes, escape rooms are proving their value as medical training tools as demonstrated by the Central Texas Veterans Health Care System. Staff there have used the concept for a flu pandemic escape room and is reporting increased staff handwashing and acceptance of flu vaccines as a result. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 28, 2021 Category: Infectious Diseases Source Type: news

Edible Cholera vaccine made of powdered rice proves safe in phase 1 human trials
(University of Tokyo) Vaccine manufacturing made enormous strides in 2020, but the complexity of SARS-CoV-2 vaccines has highlighted the value of inoculations that can be made cheaply and transported and stored without refrigeration. A new needle-free cholera vaccine has been made by grinding up genetically modified grains of rice and can be stored long-term at room temperature. This made-in-Japan innovation has shown no obvious side effects and a good immune response in its Phase 1 clinical trial. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 25, 2021 Category: Infectious Diseases Source Type: news

Changes in COVID-19-related hospitalizations, deaths after states reopened
This study evaluated changes in hospitalization and death rates related to COVID-19 before and after U.S. states reopened their economies in 2020. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 25, 2021 Category: Infectious Diseases Source Type: news

Association of childcare closures, employment of women vs men during COVID-19
(JAMA Network) What The Study Did: Researchers examined the association of closures of childcare facilities with the employment status of women and men with children in the United States during the COVID-19 pandemic. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 25, 2021 Category: Infectious Diseases Source Type: news

Assessing COVID-19 control plan on University Campus during second wave of pandemic
(JAMA Network)What The Study Did: This analysis describes the use of a multifaceted COVID-19 control plan to reduce spread of SARS-CoV-2 at a large urban university during the second wave of the pandemic. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 25, 2021 Category: Infectious Diseases Source Type: news

Making house calls when everyone's staying home: COVID-19 pandemic in Tokyo
(University of Tsukuba) Researchers from University of Tsukuba have found that the share of calls to after-hours house call medical services for fever or cold symptoms decreased during the COVID-19 pandemic in Tokyo, but that the severity of symptoms in those patients was significantly increased. Use of such services could reduce the burden on hospitals and early detection could improve patient outcomes if hesitancy to seek treatment in a pandemic can be addressed. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 25, 2021 Category: Infectious Diseases Source Type: news

Scientists discover how dengue vaccine fails to protect against disease
(University of North Carolina Health Care) Researchers discovered that a small subpopulation of antibodies binding to unique sites on each serotype are linked to protection. The research, published in the Journal of Clinical Investigation, provides important information for vaccine developers to consider when creating a dengue vaccine, which has long eluded scientists. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 25, 2021 Category: Infectious Diseases Source Type: news

Structural biology reveals new opportunities to combat tuberculosis
(European Molecular Biology Laboratory) EMBL Hamburg's Wilmanns and Kosinski groups have determined the detailed structure of a bacterial protein complex critical for tuberculosis infection. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 25, 2021 Category: Infectious Diseases Source Type: news

Study finds structural changes in the SARS-CoV-2 Alpha and Beta variants
(Boston Children's Hospital) The latest in a series of structural studies of the SARS-CoV-2 variants' " spike " protein, led by Bing Chen, PhD, at Boston Children's Hospital, reveals new properties of the Alpha (formerly U.K.) and Beta (formerly South Africa) variants. The findings suggest that the Beta variant may not be neutralized by antibodies elicited by current vaccines or by exposure to the original virus. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 25, 2021 Category: Infectious Diseases Source Type: news

Study confirms the low likelihood that SARS-CoV-2 on hospital surfaces is infectious
(University of California - Davis Health) A new study confirms the low likelihood that coronavirus contamination on hospital surfaces is infectious. The study is the original report on recovering near-complete SARS-CoV-2 genome sequences directly from surface swabs. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 25, 2021 Category: Infectious Diseases Source Type: news

COVID-linked multi-system inflammatory syndrome in children diagnosed more in Black and Latino child
(Children's National Hospital) Multisystem Inflammatory Syndrome in Children (MIS-C) significantly affected more Black and Latino children than white children, with Black children at the highest risk, according to a new observational study of 124 pediatric patients treated at Children's National Hospital in Washington, D.C. Researchers also found cardiac complications, including systolic myocardial dysfunction and valvular regurgitation, were more common in MIS-C patients who were critically ill. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 25, 2021 Category: Infectious Diseases Source Type: news

When did the first COVID-19 case arise?
(PLOS) Using methods from conservation science, a new analysis suggests that the first case of COVID-19 arose between early October and mid-November, 2019 in China, with the most likely date of origin being November 17. David Roberts of the University of Kent, U.K., and colleagues present these findings in the open-access journal PLOS Pathogens. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 24, 2021 Category: Infectious Diseases Source Type: news

Uncovered: Crucial insight into how Ebola virus evades our immune defenses
(Monash University) Monash University, Australia, researchers have discovered a key way that one of the world's deadliest pathogens, Ebola virus, evades the immune system. Understanding this process provides new potential targets for the future development of anti-viral therapies for a disease that killed over 11,000 people in an outbreak in West Africa between 2014 and 2016, with mortality rates in past outbreaks of 25% to 90%. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 24, 2021 Category: Infectious Diseases Source Type: news

Genome study reveals East Asian coronavirus epidemic 20,000 years ago
(Queensland University of Technology) An international study has discovered a coronavirus epidemic broke out in the East Asia region more than 20,000 years ago, with traces of the outbreak evident in the genetic makeup of people from that area. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 24, 2021 Category: Infectious Diseases Source Type: news