The shape of nanoparticles in body fluids may help identify the type of cancer
(Nagoya University) A recent study has shown that the shape of cell-derived nanoparticles, known as " extracellular vesicles " (EVs), in body fluids could be a biomarker for identifying types of cancer. In the study, scientists successfully measured the shape distributions of EVs derived from liver, breast, and colorectal cancer cells, showing that the shape distributions differ from one another. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 7, 2021 Category: Cancer & Oncology Source Type: news

Aging-related conditions increase treatment burden in older cancer patients
(Geisinger Health System) Having multiple chronic health conditions and living in a rural area were the top two factors affecting increased healthcare system contact among older patients with bladder cancer, a research team has found. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 7, 2021 Category: Cancer & Oncology Source Type: news

Study explores opioid prescribing preferences and practices among residents and faculty
(University of Colorado Anschutz Medical Campus) Opioid prescribing preferences and practices among surgical residents and faculty differ, according to a new study published in the journal Surgery by CU Department of Surgery researchers. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 7, 2021 Category: Cancer & Oncology Source Type: news

CNIO researchers help to decipher the structure of the large molecular machine that activates mTOR
(Centro Nacional de Investigaciones Oncol ó gicas (CNIO)) Every organism is a universe that lives thanks to the activities of tens of thousands of nanomachines, whose functions depend on their forms. Now, a group at the Spanish National Cancer Research Centre (CNIO) has helped determine the structure of a nanomachine essential for the functioning of another, mTOR, which plays fundamental roles in cancer and nutrition, ageing and other vital processes in the body. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 7, 2021 Category: Cancer & Oncology Source Type: news

Cancer screenings rebounded in 2020 after COVID but racial disparities remain
(Dana-Farber Cancer Institute) Testing returned to pre-pandemic levels in late 2020 except with colonoscopies for colorectal cancer screening, which continued to lag. Rates of mammography for breast cancer screening were lower among Black and Hispanic patients during the pandemic. Long term effects of " missed " diagnoses on cancer outcomes not yet clear. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 7, 2021 Category: Cancer & Oncology Source Type: news

Next generation cytogenetics is on its way
(Radboud University Medical Center) Dutch-French research shows that Optical Genome Mapping (OGM) detects abnormalities in chromosomes and DNA very quickly, effectively and accurately. Sometimes even better than all existing techniques together, as they describe in two proof-of-concept studies published in the American Journal of Human Genetics. This new technique could radically change the existing workflow within cytogenetic laboratories. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 7, 2021 Category: Cancer & Oncology Source Type: news

New computational technique, software identifies cell types within a tumor and its microenvironment
(Boston University School of Medicine) The discovery of novel groups or categories within diseases, organisms and biological processes and their organization into hierarchical relationships are important and recurrent pursuits in biology and medicine, which may help elucidate group-specific vulnerabilities and ultimately novel therapeutic interventions. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 7, 2021 Category: Cancer & Oncology Source Type: news

Molecular imaging improves staging and treatment of pancreatic ductal adenocarcinomas
(Society of Nuclear Medicine and Molecular Imaging) For patients with pancreatic ductal adenocarcinomas (PDAC), molecular imaging can improve staging and clinical management of the disease, according to research published in the June issue of The Journal of Nuclear Medicine. In a retrospective study of PDAC patients, the addition of PET/CT imaging with 68Ga-FAPI led to restaging of disease in more than half of the patients, most notably in those with local recurrence. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 7, 2021 Category: Cancer & Oncology Source Type: news

New AI tech for early detection of prostate cancer
(RMIT University) Researchers have developed a diagnostic tool that can spot prostate cancer before patients have any symptoms, using artificial intelligence to analyse CT scans in just seconds. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 7, 2021 Category: Cancer & Oncology Source Type: news

Biochemical pathway to skin darkening holds implications for prevention of skin cancers
(Massachusetts General Hospital) A skin pigmentation mechanism that can darken the color of human skin as a natural defense against ultraviolet (UV)-associated cancers has been discovered by scientists at Massachusetts General Hospital (MGH). (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 6, 2021 Category: Cancer & Oncology Source Type: news

Significant increase in impact factor ratings for Bentham Science journals
(Bentham Science Publishers) Bentham Science journals get appreciable increase in JCR Impact Factors, especially for Neuroscience, Cancer and Medicinal Chemistry journals. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 6, 2021 Category: Cancer & Oncology Source Type: news

New cancer findings can give wider access to immunotherapy
(Karolinska Institutet) Researchers at Karolinska Institutet in Sweden publish new findings in the journal Cancer Discovery showing how pharmacological activation of the protein p53 boosts the immune response against tumours. The results can be of significance to the development of new combination therapies that will give more cancer patients access to immunotherapy. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 6, 2021 Category: Cancer & Oncology Source Type: news

Innovation massively expands view into workings of single cells
(Oregon Health& Science University) Researchers have devised a way to multiply by more than ten-fold the accessible details of gene activity in individual cells. It's a big leap in the effort to understand cancer development, brain function, immunity and other biological processes driven by the complex interactions of multitudes of different cell types. Study publishes in Nature Biotechnology. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 6, 2021 Category: Cancer & Oncology Source Type: news

Dutch and German childhood cancer centers embark on unique research collaboration
(Princess M á xima Center for Pediatric Oncology) The Princess M á xima Center for pediatric oncology in the Netherlands is to embark on a close collaboration with German top centers in the field of childhood cancer research. With this strategic collaboration, the Princess M á xima Center and the Hopp-KiTZ childhood cancer center aim to accelerate development towards even better treatment options for children with cancer. With this 'Twinning Program', the organizations are joining forces as European centers of excellence in the field of pediatric cancer research. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 5, 2021 Category: Cancer & Oncology Source Type: news

MasSpec Pen shows promise in pancreatic cancer surgery
(University of Texas at Austin) A diagnostic tool called the MasSpec Pen has been tested for the first time in pancreatic cancer patients during surgery. The device is shown to accurately identify tissues and surgical margins directly in patients and differentiate healthy and cancerous tissue from banked pancreas samples. At about 15 seconds per analysis, the method is more than 100 times as fast as the current gold standard diagnostic. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 5, 2021 Category: Cancer & Oncology Source Type: news