Use of Prophylactic Cranial Irradiation in Patients with Limited Stage SCLC
Researchers found that using prophylactic cranial irradiation after thoracic radiation in patients with limited-stage small cell lung cancer undergoing contemporary head imaging is not associated with a decrease in risk of developing new brain metastasis. (Source: CancerNetwork)
Source: CancerNetwork - April 23, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

FDA Grants Accelerated Approval to Sacituzumab Govitecan-hziy to Treat Metastatic TNBC
The FDA granted a breakthrough therapy designation and priority review under its Accelerated Approval Program to sacituzumab govitecan-hziy for the treatment of patients with metastatic triple-negative breast cancer. (Source: CancerNetwork)
Source: CancerNetwork - April 22, 2020 Category: Cancer & Oncology Authors: Matthew Fowler Source Type: news

FDA Approves Ibrutinib Combined with Rituximab for Patients with CLL/SLL
The FDA approved ibrutinib in combination with rituximab for the initial treatment of adult patients with chronic lymphocytic leukemia/small lymphocytic lymphoma. (Source: CancerNetwork)
Source: CancerNetwork - April 22, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

FDA Grants RMAT Designation to Tisagenlecleucel for Relapsed/Refractory Follicular Lymphoma
The FDA granted regenerative medicine advanced therapy designation to tisagenlecleucel for an investigational new indication to treat patients with relapsed or refractory follicular lymphoma. (Source: CancerNetwork)
Source: CancerNetwork - April 22, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

COVID-19 May Lead to Permanent Changes in Oncology Services
During the COVID-19 pandemic, oncology teams have had to begin adopting new ways of practicing while simultaneously optimizing treatment and care, potentially leading to permanent changes in oncology services. (Source: CancerNetwork)
Source: CancerNetwork - April 22, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Phase III CheckMate-9ER Trial Meets Primary Endpoint in Advanced RCC Trial
The trial evaluated nivolumab in combination with cabozantinib compared to sunitinib in previously untreated advanced or metastatic renal cell carcinoma, meeting its primary endpoint of progression-free survival at final analysis. (Source: CancerNetwork)
Source: CancerNetwork - April 21, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

ILROG Recommends Alternative Radiation Treatment Schemes in Blood Cancer During COVID-19 Pandemic
The International Lymphoma Radiation Oncology Group laid out a set of emergency recommendations for alternative radiation treatment schemes for treating patients with hematologic malignancies during the COVID-19 pandemic. (Source: CancerNetwork)
Source: CancerNetwork - April 21, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

CheckMate-743 Trial of Nivolumab, Ipilimumab Meets Primary Endpoint in Mesothelioma Trial
The trial evaluating nivolumab in combination with ipilimumab in previously untreated malignant pleural mesothelioma met its primary endpoint of overall survival. (Source: CancerNetwork)
Source: CancerNetwork - April 21, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

James L. Mulshine, MD, on Artificial Intelligence Tools for COVID-19
The lung cancer expert spoke about the possibility of using artificial intelligence techniques to help identify patients with COVID-19. (Source: CancerNetwork)
Source: CancerNetwork - April 21, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Prognostic Tool Accurately Predicts Cancer Survival Risk
A prognostic survival model, titled PROVIEW, was able to accurately predict changing cancer survival risk over time and may have the potential to be a useful prognostic tool that can be completed by patients. (Source: CancerNetwork)
Source: CancerNetwork - April 20, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Planned Clinical Trial of Allogeneic Stem Cell Therapy Remestemcel-L in Patients with COVID-19
Mount Sinai Health System announced that they will be using the allogeneic stem cell therapy remestemcel-L in patients with COVID-19, and have already tested the therapy in 10 patients. (Source: CancerNetwork)
Source: CancerNetwork - April 20, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Determining Quality of Life in Patients with Advanced Cancer
Identifying early predictors of poor quality of life could allow for the identification of patients who may benefit from early referral to palliative and supportive care according to the researchers. (Source: CancerNetwork)
Source: CancerNetwork - April 20, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Researchers Develop Long Noncoding RNA-Based Immune Classes and Scores for Immunotherapy
A recent study determined 4 distinct long noncoding RNA-based immune classes for patients with cancer and provided scores for integration into multiomic panels for precision immunotherapy. (Source: CancerNetwork)
Source: CancerNetwork - April 20, 2020 Category: Cancer & Oncology Authors: Matthew Fowler Source Type: news

Immunotherapy After Chemotherapy Could Slow Progression of Urothelial Cancer
A recent study found that switch maintenance therapy after first-line platinum-based chemotherapy led to higher objective response rates and longer progression-free survival for patients of urothelial cancer. (Source: CancerNetwork)
Source: CancerNetwork - April 19, 2020 Category: Cancer & Oncology Authors: Matthew Fowler Source Type: news

Adjuvant Chemoendocrine Therapy May Be Associated With Cognitive Impairment
Results from a subgroup of the TAILORx trial suggested that adjuvant chemoendocrine therapy is associated with significantly greater cancer-related cognitive impairment compared with endocrine therapy alone. (Source: CancerNetwork)
Source: CancerNetwork - April 19, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news