Synodos does it again: Breaking barriers to solve the 'impossible' problems
(Children's Tumor Foundation) Treatment for low-grade gliomas in patients living with neurofibromatosis type 1 are now one step closer thanks to recent research discoveries initiated and funded by the Children's Tumor Foundation. The Foundation's SYNODOS consortium has just recently been published in Nature Medicine, showing that immunotherapy has the potential to impact gliomas. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 27, 2018 Category: Cancer & Oncology Source Type: news
What Causes Hyperpigmentation?
Discussion
Skin color is primarily due to genetic factors. Melanocytes are usually found in skin in the basal layer of the epidermis which is also where the melanin usually lies. There are a range of normal skin phenotypes that have been described by Fitzpatrick and range from I-VI:
I – pale white skin, blond hair, blue eyed, does not tan, always burns
II – fair skin, blue eyed, tans poorly, burns easily
III – darker white skin, burns initially then tans
IV – light brown skin, tans easily, burns minimally
V – brown skin, tans darkly easily, burns rarely
VI – dark brown skin, alway...
Source: PediatricEducation.org - December 17, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Open science and data initiative announced for neurofibromatosis
(Children's Tumor Foundation) The Children's Tumor Foundation, together with the Neurofibromatosis Therapeutic Acceleration Program and Sage Bionetworks, has announced the first-ever open data portal for scientific research results in the field of neurofibromatosis (NF). The NF Data Portal marks the major first milestone in all three organizations' commitment to the development of the larger NF Open Science Initiative (NF-OSI), which draws experts from across research disciplines and disease areas in order to develop treatments for NF. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 14, 2018 Category: International Medicine & Public Health Source Type: news
Some brain tumors may respond to immunotherapy, new study suggests
(Columbia University Irving Medical Center) A new study suggests that a slow-growing brain tumor arising in patients affected by neurofibromatosis type 1 (NF1) may be vulnerable to immunotherapy, which gives the immune system a boost in fighting cancer. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 10, 2018 Category: International Medicine & Public Health Source Type: news
Mother who is covered in tumours has accepted her looks after her son was born with the disorder
Vanessa Cornelio, 25, from Glendale, Arizona, was born with neurofibromatosis, which causes tumours to grow on nerve tissue. Her two-year-old son Daniel Jr. inherited the condition. (Source: the Mail online | Health)
Source: the Mail online | Health - November 6, 2018 Category: Consumer Health News Source Type: news
Pakistani man covered in hundreds of bubble-like tumours
Ameer Ali, from Sehwan Sharif in Pakistan's Sindh province, has had small tumours on his abdomen and back since his childhood. Doctors believe he has a severe case of neurofibromatosis. (Source: the Mail online | Health)
Source: the Mail online | Health - October 8, 2018 Category: Consumer Health News Source Type: news
Pakistani man, 32, covered in hundreds of bubble-like tumours
Ameer Ali, from Sehwan Sharif in Pakistan's Sindh province, has had small tumours on his abdomen and back since his childhood. Doctors believe he has a severe case of neurofibromatosis. (Source: the Mail online | Health)
Source: the Mail online | Health - October 8, 2018 Category: Consumer Health News Source Type: news
Social worker who is covered from head to toe in tiny tumours has been refused into swimming pools
Gail Appelgren, 57, from Edmonton in Alberta, Canada, has battled with neurofibromatosis her whole life, which she believes makes her 'special' despite cruel comments from strangers. (Source: the Mail online | Health)
Source: the Mail online | Health - September 6, 2018 Category: Consumer Health News Source Type: news
Social worker who is covered from head to toe in tiny tumours has been refused into swimming pools
Gail Applegren, 57, from Edmonton in Alberta, Canada, has battled with neurofibromatosis her whole life, which she believes makes her 'special' despite cruel comments from strangers. (Source: the Mail online | Health)
Source: the Mail online | Health - September 5, 2018 Category: Consumer Health News Source Type: news
Screening for Neuroendocrine Tumors Is Recommended for NF1 Patients
A study on pheochromocytoma and paraganglioma associated with neurofibromatosis type 1 highlights how screening for these malignancies is important. (Source: CancerNetwork)
Source: CancerNetwork - August 28, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news
Selumetinib granted orphan designation in Europe for neurofibromatosis type 1
AstraZeneca and Merck & Co., Inc., Kenilworth, NJ, US (known as MSD outside the US and Canada) announced that the European Medicines Agency (EMA) has granted orphan designation to selumetinib, a MEK 1/2 inhibitor, for the treatment of neurofibromatosis type 1 (NF1). (Source: World Pharma News)
Source: World Pharma News - August 9, 2018 Category: Pharmaceuticals Tags: Featured AstraZeneca Business and Industry Source Type: news
Indian teen is unable to walk due to her 'defunct' claw-like fist
Mita Sabar, 18, from a remote village in Odisha, east India, is thought to be suffering from plexiform neurofibromatosis, which means her hand is so heavy she is unable to lift it. (Source: the Mail online | Health)
Source: the Mail online | Health - August 8, 2018 Category: Consumer Health News Source Type: news
The teenager with a 22lb hand: 18-year-old is unable to walk due to her 'defunct', claw-like fist
Mita Sabar, 18, from a remote village in Odisha, east India, is thought to be suffering from plexiform neurofibromatosis, which means her hand is so heavy she is unable to lift it. (Source: the Mail online | Health)
Source: the Mail online | Health - August 8, 2018 Category: Consumer Health News Source Type: news
Children's Tumor Foundation Drug Discovery Awards announced
(Children's Tumor Foundation) The Children's Tumor Foundation (CTF), the largest non-governmental funder of neurofibromatosis (NF) research, and PLOS ONE, a leading peer-reviewed scientific journal, are pleased to announce the successful completion of the first funding cycle of the Drug Discovery Initiative Registered Report (DDIRR) 2017 Awards, a funder-publisher partnership integrating the Registered Reports model into the grant application process. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 11, 2018 Category: International Medicine & Public Health Source Type: news
Indian grandfather's tumours left him unable to eat, talk or speak
Subhash Chand, 54, from Uttar Pradesh state in India, suffers from a condition known as Neurofibromatosis or Von Recklinghausen's Disease. He developed the disorder at just 20 years old. (Source: the Mail online | Health)
Source: the Mail online | Health - May 15, 2018 Category: Consumer Health News Source Type: news
