Dermatitis and prolonged dysesthesia from the poisonous wood nettle, Dendrocnide meyeniana (Urticaceae)
Australas J Dermatol. 2024 Apr 14. doi: 10.1111/ajd.14252. Online ahead of print.NO ABSTRACTPMID:38616498 | DOI:10.1111/ajd.14252 (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - April 15, 2024 Category: Dermatology Authors: Johannes F Dayrit Bryan Edgar K Guevara Lunardi Bintanjoyo Scott A Norton Source Type: research
Molecules, Vol. 29, Pages 1765: Evaluation of Urtica dioica Phytochemicals against Therapeutic Targets of Allergic Rhinitis Using Computational Studies
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Allergic rhinitis (AR) is a prevalent inflammatory condition affecting millions globally, with current treatments often associated with significant side effects. To seek safer and more effective alternatives, natural sources like Urtica dioica (UD) are being explored. However, UD’s mechanism of action remains unknown. Therefore, to elucidate it, we conducted an in silico evaluation of UD phytochemicals’ effects on known therapeutic targets of allergic rhinitis: histamine receptor 1 (HR1), neurokinin 1 receptor (NK1R), cysteinyl leukotriene receptor 1 (CLR1), chemoattractant receptor-homo...
Source: Molecules - April 12, 2024 Category: Chemistry Authors: Erick Bahena Culhuac Martiniano Bello Tags: Article Source Type: research
Plant Soup Formulations Show Cholinesterase Inhibition Potential in the Prevention of Alzheimer's Disease
CONCLUSION: The outcomes of our study should serve as a catalyst for further exploration of this important research domain. Our current research focuses on deeper insights into the potential of comprehensive meal options. Furthermore, the synergy/antagonism/non-interaction between respective soup ingredients as well as elements of individual soups' chemical composition is a very interesting topic currently under our intensive scientific investigation.PMID:38523524 | DOI:10.2174/0115672050306101240321050146 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - March 25, 2024 Category: Neurology Authors: Dorota Gajowniczek-A łasa Dominik Szwajgier Ewa Baranowska-W ójcik Source Type: research
Effects of a proprietary mixture of extracts from Sabal serrulata fruits and Urtica dioica roots (WS ® 1541) on prostate hyperplasia and inflammation in rats and human cells
Conclusion: This data supports a beneficial effect of the clinically used WS® 1541 for the treatment of lower urinary tract symptoms associated with mild to moderate benign prostate syndrome and provides a scientific rationale for the combination of its components WS® 1473 and WS® 1031. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - March 15, 2024 Category: Drugs & Pharmacology Source Type: research
Phytotherapy Might Have a Role in Reducing Unnecessary Prostate Biopsies: Results from an Exploratory, Randomized Controlled Trial of Two Different Phytotherapeutic Agents
CONCLUSIONS: In conclusion, a three-month course of a combination of Curcuma Longa, Boswellia, Pinus pinaster and Urtica dioica seems to be an interesting tool to avoid unnecessary prostate biopsies among men with higher-than-normal PSA levels.PMID:38391402 | PMC:PMC10888467 | DOI:10.3390/clinpract14010016 (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - February 23, 2024 Category: Cancer & Oncology Authors: Tommaso Cai Irene Tamanini Marco Puglisi Leonardo Bizzotto Michele Rizzo Giovanni Liguori Luca Gallelli Alessandro Palmieri Truls E Bjerklund Johansen Source Type: research
Phytotherapy Might Have a Role in Reducing Unnecessary Prostate Biopsies: Results from an Exploratory, Randomized Controlled Trial of Two Different Phytotherapeutic Agents
CONCLUSIONS: In conclusion, a three-month course of a combination of Curcuma Longa, Boswellia, Pinus pinaster and Urtica dioica seems to be an interesting tool to avoid unnecessary prostate biopsies among men with higher-than-normal PSA levels.PMID:38391402 | DOI:10.3390/clinpract14010016 (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - February 23, 2024 Category: Cancer & Oncology Authors: Tommaso Cai Irene Tamanini Marco Puglisi Leonardo Bizzotto Michele Rizzo Giovanni Liguori Luca Gallelli Alessandro Palmieri Truls E Bjerklund Johansen Source Type: research
The role of stinging nettle (Urtica dioica L.) in the management of rotenone-induced Parkinson's disease in rats
Tissue Cell. 2024 Feb 15;87:102328. doi: 10.1016/j.tice.2024.102328. Online ahead of print.ABSTRACTParkinson's disease (PD) is one of the most common neurodegenerative conditions. Alpha-synuclein deposition, Lewy bodies (LBs) formation, disruption of the autophagic machinery, apoptosis of substantia nigra dopaminergic neurons, oxidative stress, and neuroinflammation are all pathologic hallmarks of PD. The leaves of the stinging Nettle (Urtica dioica L.) have a long history as an herbal cure with antioxidant, anti-inflammatory, anti-cancer, immunomodulatory, and neuroprotective properties. The current study aims for the fir...
Source: Tissue and Cell - February 22, 2024 Category: Cytology Authors: Emad Albadawi Ahmed El-Tokhy Muayad Albadrani Mohammed Adel Randa El-Gamal Wael Zaarina Mosaab Salah El-Din El-Agawy Hassan Reda Hassan Elsayed Source Type: research
The role of stinging nettle (Urtica dioica L.) in the management of rotenone-induced Parkinson's disease in rats
Tissue Cell. 2024 Feb 15;87:102328. doi: 10.1016/j.tice.2024.102328. Online ahead of print.ABSTRACTParkinson's disease (PD) is one of the most common neurodegenerative conditions. Alpha-synuclein deposition, Lewy bodies (LBs) formation, disruption of the autophagic machinery, apoptosis of substantia nigra dopaminergic neurons, oxidative stress, and neuroinflammation are all pathologic hallmarks of PD. The leaves of the stinging Nettle (Urtica dioica L.) have a long history as an herbal cure with antioxidant, anti-inflammatory, anti-cancer, immunomodulatory, and neuroprotective properties. The current study aims for the fir...
Source: Tissue and Cell - February 22, 2024 Category: Cytology Authors: Emad Albadawi Ahmed El-Tokhy Muayad Albadrani Mohammed Adel Randa El-Gamal Wael Zaarina Mosaab Salah El-Din El-Agawy Hassan Reda Hassan Elsayed Source Type: research
Urtica dioica extract mitigates doxorubicin-induced hepatotoxicity and nephrotoxicity by suppressing oxidative stress and modulating biochemical indices: In vivo and molecular docking study
This study evaluated the hepatoprotective and nephroprotective effects of ethanol extracts ofUrtica dioica (UD) leaves on doxorubicin-induced oxidative stress. This study comprised 5 groups: control, doxorubicin (DOX: 15 mg/kg), UD-treated group (DOX + 300 mg/kg), a second UD-treated group (DOX + 600 mg/kg), and UD-treated group (600 mg/kg alone). The in vitro antioxidant potential of UD was as sayed with FRAP and DPPH, and GCMS-identified UD phytoconstituents were docked against NADPH oxidase (2CDU) and nitric oxide synthase (2FLQ) using molecular docking tools such as Discovery Studio, Open Babel, and PyRX...
Source: Comparative Clinical Pathology - February 20, 2024 Category: Pathology Source Type: research
Molecules, Vol. 29, Pages 749: Combined Application of Fluorescence Spectroscopy and Principal Component Analysis in Characterisation of Selected Herbhoneys
This study reports the use of front-face fluorescence spectroscopy with principal component analysis (PCA) as a tool for the characterisation of selected Polish herbhoneys (raspberry, lemon balm, rose, mint, black current, instant coffee, pine, hawthorn, and nettle). Fluorimetric spectra registered in the ranges ascribed to fluorescence of amino acids, polyphenols, vitamins, and products of Maillard’s reaction enabled the comparison of herbhoney compositions. Obtained synchronous spectra combined with PCA were used to investigate potential differences between analysed samples and interactions between compound...
Source: Molecules - February 6, 2024 Category: Chemistry Authors: Joanna Bana ś Marian Bana ś Tags: Article Source Type: research
The Relationship Between Perceived Uncontrollable Mortality Risk and Health Effort: Replication, Secondary Analysis, and Mini Meta-analysis
CONCLUSIONS: Our findings offer support for the role of PUMR in mediating the relationship between subjective socioeconomic position and health effort. The results highlight the importance of measuring and understanding PUMR in studying socioeconomic inequalities in health behaviors. We discuss potential areas for future research, including determining the accuracy of PUMR, investigating influential cues, examining the role of media in shaping risk perceptions, and understanding individuals' awareness of their own perceptions of mortality risk.PMID:38190133 | PMC:PMC10858306 | DOI:10.1093/abm/kaad072 (Source: Annals of Behavioral Medicine)
Source: Annals of Behavioral Medicine - January 8, 2024 Category: Psychiatry & Psychology Authors: Richard Brown Gillian Pepper Source Type: research
The Relationship Between Perceived Uncontrollable Mortality Risk and Health Effort: Replication, Secondary Analysis, and Mini Meta-analysis
CONCLUSIONS: Our findings offer support for the role of PUMR in mediating the relationship between subjective socioeconomic position and health effort. The results highlight the importance of measuring and understanding PUMR in studying socioeconomic inequalities in health behaviors. We discuss potential areas for future research, including determining the accuracy of PUMR, investigating influential cues, examining the role of media in shaping risk perceptions, and understanding individuals' awareness of their own perceptions of mortality risk.PMID:38190133 | DOI:10.1093/abm/kaad072 (Source: Annals of Behavioral Medicine)
Source: Annals of Behavioral Medicine - January 8, 2024 Category: Psychiatry & Psychology Authors: Richard Brown Gillian Pepper Source Type: research
Sono-Microwave Assisted Chlorine free and Ionic Liquid (SMACIL) extraction of cellulose from Urtica dioica: A benign to green approach
This study investigated the impact of benign and green solvents on the extraction, thermal stability, mechanical properties, and crystallinity of cellulose extracted from Urtica dioica (Stinging nettle) using a Sono-Microwave Assisted Chlorine free and Ionic Liquid (SMACIL) extraction technique. In this regard, the stalks were undergone through pre chemical treatment before starting bleaching them with hydrogen peroxide (HPO) and 1-butyl-3-methylimidazolium acetate (BMIM-Ac) having different mole ratios (5, 7.5, and 10) to expose cellulose. The Urtica dioica cellulose (UDC) was characterized using FTIR, tensile testing, FE...
Source: International Journal of Biological Macromolecules - January 5, 2024 Category: Biochemistry Authors: Sobia Naseem Arjumand Iqbal Durrani Muhammad Rizwan Farhat Yasmeen Sofia Siddiqui Farzana Habib Source Type: research
Exploring the synergistic potential of wild nettle and olive oil: bioactive compounds, antioxidant capacity, and antibacterial properties
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Source: International Journal of Environmental Health Research - December 4, 2023 Category: Environmental Health Authors: Hedia Manai-DjebaliWalid YeddesMajdi HammamiSalma Nait-MohamedEmna HabachiKamel MsaadaNabil Ben Youssefa Laboratory of Olive Biotechnology, Biotechnology Center of Borj-Cedria, BP, Hammam-Lif, Tunisiab Laboratory of Aromatic and Medicinal Plants, Biotechn Source Type: research
