The early recognition and diagnosis of neoplastic meningitis
Expert Rev Neurother. 2023 Dec 25:1-12. doi: 10.1080/14737175.2023.2295999. Online ahead of print.ABSTRACTINTRODUCTION: The diagnosis and monitoring of leptomeningeal metastases (LM) from solid tumors are challenging, and the combination of neurological symptoms, MRI findings, and cerebrospinal fluid (CSF) cytology does not always allow to achieve a definitive diagnosis.AREAS COVERED: This review summarizes the studies that have investigated CSF liquid biopsy to improve the initial diagnosis of LM in case the CSF cytology is negative or only suspicious for tumor cells, and monitoring of tumor response following targeted th...
Source: Expert Review of Neurotherapeutics - December 25, 2023 Category: Neurology Authors: Alessia Pellerino Luca Bertero Edoardo Pronello Roberta Rud à Riccardo Soffietti Source Type: research
An overview of the therapeutic strategies for neoplastic meningitis due to breast cancer: when and why?
Expert Rev Neurother. 2023 Dec 25:1-27. doi: 10.1080/14737175.2023.2293223. Online ahead of print.ABSTRACTINTRODUCTION: Neoplastic meningitis (NM), also known as leptomeningeal carcinomatosis, is characterized by the infiltration of tumor cells into the meninges, and poses a significant therapeutic challenge owing to its aggressive nature and limited treatment options. Breast cancer is a common cause of NM among solid tumors, further highlighting the urgent need to explore effective therapeutic strategies. This review aims to provide insights into the evolving landscape of NM therapy in breast cancer by collating existing ...
Source: Expert Review of Neurotherapeutics - December 25, 2023 Category: Neurology Authors: Mainak Bardhan Debankur Dey Vinay Suresh Binish Javed Vyshak Alva Venur Neha Joe Ritvika Kalidindi Ahmad Ozair Marium Khan Reshma Mahtani Simon Lo Yazmin Odia Manmeet S Ahluwalia Source Type: research
The early recognition and diagnosis of neoplastic meningitis
Expert Rev Neurother. 2023 Dec 25:1-12. doi: 10.1080/14737175.2023.2295999. Online ahead of print.ABSTRACTINTRODUCTION: The diagnosis and monitoring of leptomeningeal metastases (LM) from solid tumors are challenging, and the combination of neurological symptoms, MRI findings, and cerebrospinal fluid (CSF) cytology does not always allow to achieve a definitive diagnosis.AREAS COVERED: This review summarizes the studies that have investigated CSF liquid biopsy to improve the initial diagnosis of LM in case the CSF cytology is negative or only suspicious for tumor cells, and monitoring of tumor response following targeted th...
Source: Expert Review of Neurotherapeutics - December 25, 2023 Category: Neurology Authors: Alessia Pellerino Luca Bertero Edoardo Pronello Roberta Rud à Riccardo Soffietti Source Type: research
An overview of the therapeutic strategies for neoplastic meningitis due to breast cancer: when and why?
Expert Rev Neurother. 2023 Dec 25:1-27. doi: 10.1080/14737175.2023.2293223. Online ahead of print.ABSTRACTINTRODUCTION: Neoplastic meningitis (NM), also known as leptomeningeal carcinomatosis, is characterized by the infiltration of tumor cells into the meninges, and poses a significant therapeutic challenge owing to its aggressive nature and limited treatment options. Breast cancer is a common cause of NM among solid tumors, further highlighting the urgent need to explore effective therapeutic strategies. This review aims to provide insights into the evolving landscape of NM therapy in breast cancer by collating existing ...
Source: Expert Review of Neurotherapeutics - December 25, 2023 Category: Neurology Authors: Mainak Bardhan Debankur Dey Vinay Suresh Binish Javed Vyshak Alva Venur Neha Joe Ritvika Kalidindi Ahmad Ozair Marium Khan Reshma Mahtani Simon Lo Yazmin Odia Manmeet S Ahluwalia Source Type: research
The early recognition and diagnosis of neoplastic meningitis
Expert Rev Neurother. 2023 Dec 25:1-12. doi: 10.1080/14737175.2023.2295999. Online ahead of print.ABSTRACTINTRODUCTION: The diagnosis and monitoring of leptomeningeal metastases (LM) from solid tumors are challenging, and the combination of neurological symptoms, MRI findings, and cerebrospinal fluid (CSF) cytology does not always allow to achieve a definitive diagnosis.AREAS COVERED: This review summarizes the studies that have investigated CSF liquid biopsy to improve the initial diagnosis of LM in case the CSF cytology is negative or only suspicious for tumor cells, and monitoring of tumor response following targeted th...
Source: Expert Review of Neurotherapeutics - December 25, 2023 Category: Neurology Authors: Alessia Pellerino Luca Bertero Edoardo Pronello Roberta Rud à Riccardo Soffietti Source Type: research
An overview of the therapeutic strategies for neoplastic meningitis due to breast cancer: when and why?
Expert Rev Neurother. 2024 Jan-Jun;24(1):77-103. doi: 10.1080/14737175.2023.2293223. Epub 2024 Jan 8.ABSTRACTINTRODUCTION: Neoplastic meningitis (NM), also known as leptomeningeal carcinomatosis, is characterized by the infiltration of tumor cells into the meninges, and poses a significant therapeutic challenge owing to its aggressive nature and limited treatment options. Breast cancer is a common cause of NM among solid tumors, further highlighting the urgent need to explore effective therapeutic strategies. This review aims to provide insights into the evolving landscape of NM therapy in breast cancer by collating existi...
Source: Expert Review of Neurotherapeutics - December 25, 2023 Category: Neurology Authors: Mainak Bardhan Debankur Dey Vinay Suresh Binish Javed Vyshak Alva Venur Neha Joe Ritvika Kalidindi Ahmad Ozair Marium Khan Reshma Mahtani Simon Lo Yazmin Odia Manmeet S Ahluwalia Source Type: research
The early recognition and diagnosis of neoplastic meningitis
Expert Rev Neurother. 2024 Jan-Jun;24(1):105-116. doi: 10.1080/14737175.2023.2295999. Epub 2024 Jan 8.ABSTRACTINTRODUCTION: The diagnosis and monitoring of leptomeningeal metastases (LM) from solid tumors are challenging, and the combination of neurological symptoms, MRI findings, and cerebrospinal fluid (CSF) cytology does not always allow to achieve a definitive diagnosis.AREAS COVERED: This review summarizes the studies that have investigated CSF liquid biopsy to improve the initial diagnosis of LM in case the CSF cytology is negative or only suspicious for tumor cells, and monitoring of tumor response following targete...
Source: Expert Review of Neurotherapeutics - December 25, 2023 Category: Neurology Authors: Alessia Pellerino Luca Bertero Edoardo Pronello Roberta Rud à Riccardo Soffietti Source Type: research
An overview of the therapeutic strategies for neoplastic meningitis due to breast cancer: when and why?
Expert Rev Neurother. 2024 Jan-Jun;24(1):77-103. doi: 10.1080/14737175.2023.2293223. Epub 2024 Jan 8.ABSTRACTINTRODUCTION: Neoplastic meningitis (NM), also known as leptomeningeal carcinomatosis, is characterized by the infiltration of tumor cells into the meninges, and poses a significant therapeutic challenge owing to its aggressive nature and limited treatment options. Breast cancer is a common cause of NM among solid tumors, further highlighting the urgent need to explore effective therapeutic strategies. This review aims to provide insights into the evolving landscape of NM therapy in breast cancer by collating existi...
Source: Expert Review of Neurotherapeutics - December 25, 2023 Category: Neurology Authors: Mainak Bardhan Debankur Dey Vinay Suresh Binish Javed Vyshak Alva Venur Neha Joe Ritvika Kalidindi Ahmad Ozair Marium Khan Reshma Mahtani Simon Lo Yazmin Odia Manmeet S Ahluwalia Source Type: research
The early recognition and diagnosis of neoplastic meningitis
Expert Rev Neurother. 2024 Jan-Jun;24(1):105-116. doi: 10.1080/14737175.2023.2295999. Epub 2024 Jan 8.ABSTRACTINTRODUCTION: The diagnosis and monitoring of leptomeningeal metastases (LM) from solid tumors are challenging, and the combination of neurological symptoms, MRI findings, and cerebrospinal fluid (CSF) cytology does not always allow to achieve a definitive diagnosis.AREAS COVERED: This review summarizes the studies that have investigated CSF liquid biopsy to improve the initial diagnosis of LM in case the CSF cytology is negative or only suspicious for tumor cells, and monitoring of tumor response following targete...
Source: Expert Review of Neurotherapeutics - December 25, 2023 Category: Neurology Authors: Alessia Pellerino Luca Bertero Edoardo Pronello Roberta Rud à Riccardo Soffietti Source Type: research
An overview of the therapeutic strategies for neoplastic meningitis due to breast cancer: when and why?
Expert Rev Neurother. 2024 Jan-Jun;24(1):77-103. doi: 10.1080/14737175.2023.2293223. Epub 2024 Jan 8.ABSTRACTINTRODUCTION: Neoplastic meningitis (NM), also known as leptomeningeal carcinomatosis, is characterized by the infiltration of tumor cells into the meninges, and poses a significant therapeutic challenge owing to its aggressive nature and limited treatment options. Breast cancer is a common cause of NM among solid tumors, further highlighting the urgent need to explore effective therapeutic strategies. This review aims to provide insights into the evolving landscape of NM therapy in breast cancer by collating existi...
Source: Expert Review of Neurotherapeutics - December 25, 2023 Category: Neurology Authors: Mainak Bardhan Debankur Dey Vinay Suresh Binish Javed Vyshak Alva Venur Neha Joe Ritvika Kalidindi Ahmad Ozair Marium Khan Reshma Mahtani Simon Lo Yazmin Odia Manmeet S Ahluwalia Source Type: research
The early recognition and diagnosis of neoplastic meningitis
Expert Rev Neurother. 2024 Jan-Jun;24(1):105-116. doi: 10.1080/14737175.2023.2295999. Epub 2024 Jan 8.ABSTRACTINTRODUCTION: The diagnosis and monitoring of leptomeningeal metastases (LM) from solid tumors are challenging, and the combination of neurological symptoms, MRI findings, and cerebrospinal fluid (CSF) cytology does not always allow to achieve a definitive diagnosis.AREAS COVERED: This review summarizes the studies that have investigated CSF liquid biopsy to improve the initial diagnosis of LM in case the CSF cytology is negative or only suspicious for tumor cells, and monitoring of tumor response following targete...
Source: Expert Review of Neurotherapeutics - December 25, 2023 Category: Neurology Authors: Alessia Pellerino Luca Bertero Edoardo Pronello Roberta Rud à Riccardo Soffietti Source Type: research
An overview of the therapeutic strategies for neoplastic meningitis due to breast cancer: when and why?
Expert Rev Neurother. 2024 Jan-Jun;24(1):77-103. doi: 10.1080/14737175.2023.2293223. Epub 2024 Jan 8.ABSTRACTINTRODUCTION: Neoplastic meningitis (NM), also known as leptomeningeal carcinomatosis, is characterized by the infiltration of tumor cells into the meninges, and poses a significant therapeutic challenge owing to its aggressive nature and limited treatment options. Breast cancer is a common cause of NM among solid tumors, further highlighting the urgent need to explore effective therapeutic strategies. This review aims to provide insights into the evolving landscape of NM therapy in breast cancer by collating existi...
Source: Expert Review of Neurotherapeutics - December 25, 2023 Category: Neurology Authors: Mainak Bardhan Debankur Dey Vinay Suresh Binish Javed Vyshak Alva Venur Neha Joe Ritvika Kalidindi Ahmad Ozair Marium Khan Reshma Mahtani Simon Lo Yazmin Odia Manmeet S Ahluwalia Source Type: research
The early recognition and diagnosis of neoplastic meningitis
Expert Rev Neurother. 2024 Jan-Jun;24(1):105-116. doi: 10.1080/14737175.2023.2295999. Epub 2024 Jan 8.ABSTRACTINTRODUCTION: The diagnosis and monitoring of leptomeningeal metastases (LM) from solid tumors are challenging, and the combination of neurological symptoms, MRI findings, and cerebrospinal fluid (CSF) cytology does not always allow to achieve a definitive diagnosis.AREAS COVERED: This review summarizes the studies that have investigated CSF liquid biopsy to improve the initial diagnosis of LM in case the CSF cytology is negative or only suspicious for tumor cells, and monitoring of tumor response following targete...
Source: Expert Review of Neurotherapeutics - December 25, 2023 Category: Neurology Authors: Alessia Pellerino Luca Bertero Edoardo Pronello Roberta Rud à Riccardo Soffietti Source Type: research
An overview of the therapeutic strategies for neoplastic meningitis due to breast cancer: when and why?
Expert Rev Neurother. 2024 Jan-Jun;24(1):77-103. doi: 10.1080/14737175.2023.2293223. Epub 2024 Jan 8.ABSTRACTINTRODUCTION: Neoplastic meningitis (NM), also known as leptomeningeal carcinomatosis, is characterized by the infiltration of tumor cells into the meninges, and poses a significant therapeutic challenge owing to its aggressive nature and limited treatment options. Breast cancer is a common cause of NM among solid tumors, further highlighting the urgent need to explore effective therapeutic strategies. This review aims to provide insights into the evolving landscape of NM therapy in breast cancer by collating existi...
Source: Expert Review of Neurotherapeutics - December 25, 2023 Category: Neurology Authors: Mainak Bardhan Debankur Dey Vinay Suresh Binish Javed Vyshak Alva Venur Neha Joe Ritvika Kalidindi Ahmad Ozair Marium Khan Reshma Mahtani Simon Lo Yazmin Odia Manmeet S Ahluwalia Source Type: research
The early recognition and diagnosis of neoplastic meningitis
Expert Rev Neurother. 2024 Jan-Jun;24(1):105-116. doi: 10.1080/14737175.2023.2295999. Epub 2024 Jan 8.ABSTRACTINTRODUCTION: The diagnosis and monitoring of leptomeningeal metastases (LM) from solid tumors are challenging, and the combination of neurological symptoms, MRI findings, and cerebrospinal fluid (CSF) cytology does not always allow to achieve a definitive diagnosis.AREAS COVERED: This review summarizes the studies that have investigated CSF liquid biopsy to improve the initial diagnosis of LM in case the CSF cytology is negative or only suspicious for tumor cells, and monitoring of tumor response following targete...
Source: Expert Review of Neurotherapeutics - December 25, 2023 Category: Neurology Authors: Alessia Pellerino Luca Bertero Edoardo Pronello Roberta Rud à Riccardo Soffietti Source Type: research
